Experiencia y trabajo en grupo para la cooperación y el aprendizaje en estudios de grado. Propuesta de un caso

[SPA]Esta investigación presenta un estudio sobre la importancia de la implantación del trabajo cooperativo en los estudios de grado. Partiendo del grupo como lugar de aprendizaje, de algunas aplicaciones de la psicología de los grupos y del trabajo cooperativo, se elabora la programación y el seguimiento tutorial de una asignatura de grado. Mediante la elaboración de esta asignatura, incluida dentro del marco de las Ciencias Sociales, mostramos la importancia de utilizar herramientas de trabajo donde el alumnado adquiera el conocimiento de forma activa, reflexione sobre la información recibida y aprenda a actuar en relación. Esta educación genera competencias que facilitan a las alumnas y a los alumnos su crecimiento y desarrollo vital. [ENG]The research shows an analysis about the importance of introducing cooperative working in Bachelor’s degrees. A program and monitoring of a bachelor’s degree subjects have been developed based on the concept of group and the theoretical postulates which analyse some of the main issues of working group or cooperative working. The interest of using tools where the student could achieve knowledge as an active way, reflect on the information received and learn to act as a group has been presented by means of preparation of this subject included within the Social Sciences. Active education generates instrumental and individual competencies that help student’s growth and education’s vital development.Campus Mare Nostrum, Universidad Politécnica de Cartagena, Universidad de Murcia, Región de Murci

Using Interpretable Machine Learning to Identify Baseline Predictive Factors of Remission and Drug Durability in Crohn’s Disease Patients on Ustekinumab

Ustekinumab has shown efficacy in Crohn's Disease (CD) patients. To identify patient profiles of those who benefit the most from this treatment would help to position this drug in the therapeutic paradigm of CD and generate hypotheses for future trials. The objective of this analysis was to determine whether baseline patient characteristics are predictive of remission and the drug durability of ustekinumab, and whether its positioning with respect to prior use of biologics has a significant effect after correcting for disease severity and phenotype at baseline using interpretable machine learning. Patients' data from SUSTAIN, a retrospective multicenter single-arm cohort study, were used. Disease phenotype, baseline laboratory data, and prior treatment characteristics were documented. Clinical remission was defined as the Harvey Bradshaw Index <= 4 and was tracked longitudinally. Drug durability was defined as the time until a patient discontinued treatment. A total of 439 participants from 60 centers were included and a total of 20 baseline covariates considered. Less exposure to previous biologics had a positive effect on remission, even after controlling for baseline disease severity using a non-linear, additive, multivariable model. Additionally, age, body mass index, and fecal calprotectin at baseline were found to be statistically significant as independent negative risk factors for both remission and drug survival, with further risk factors identified for remission

Long-Term Real-World Effectiveness and Safety of Ustekinumab in Crohn’s Disease Patients: The SUSTAIN Study

Background Large real-world-evidence studies are required to confirm the durability of response, effectiveness, and safety of ustekinumab in Crohn’s disease (CD) patients in real-world clinical practice. Methods A retrospective, multicentre study was conducted in Spain in patients with active CD who had received ≥1 intravenous dose of ustekinumab for ≥6 months. Primary outcome was ustekinumab retention rate; secondary outcomes were to identify predictive factors for drug retention, short-term remission (week 16), loss of response and predictive factors for short-term efficacy and loss of response, and ustekinumab safety. Results A total of 463 patients were included. Mean baseline Harvey-Bradshaw Index was 8.4. A total of 447 (96.5%) patients had received prior biologic therapy, 141 (30.5%) of whom had received ≥3 agents. In addition, 35.2% received concomitant immunosuppressants, and 47.1% had ≥1 abdominal surgery. At week 16, 56% had remission, 70% had response, and 26.1% required dose escalation or intensification; of these, 24.8% did not subsequently reduce dose. After a median follow-up of 15 months, 356 (77%) patients continued treatment. The incidence rate of ustekinumab discontinuation was 18% per patient-year of follow-up. Previous intestinal surgery and concomitant steroid treatment were associated with higher risk of ustekinumab discontinuation, while a maintenance schedule every 12 weeks had a lower risk; neither concomitant immunosuppressants nor the number of previous biologics were associated with ustekinumab discontinuation risk. Fifty adverse events were reported in 39 (8.4%) patients; 4 of them were severe (2 infections, 1 malignancy, and 1 fever). Conclusions Ustekinumab is effective and safe as short- and long-term treatment in a refractory cohort of CD patients in real-world clinical practice

Palabras femeninas que nombran la injusticia en los cuidados familiares

Esta tesis se inscribe en una trayectoria de pensamiento libre de la diferencia sexual para nombrar en femenino la injusticia. Estudia específicamente lo negativo que encierra la creación y la gestión de la casa, el trabajo, el matrimonio y la maternidad. Teniendo en cuenta la teoría psicosocial sobre la percepción de injusticia y siguiendo la necesidad de ampliar el conocimiento de la justicia, la investigación profundiza en la representación de la injusticia en lengua materna. Participan 95 mujeres de la Región de Murcia narrando el trabajo y los cuidados en el ámbito doméstico y familiar. Se han utilizado varias metodologías y teorías de investigación: teoría feminista, teoría basada en los datos y psicología discursiva. La hipótesis de trabajo principal es que las palabras de las mujeres trascienden el sentido corriente de la injusticia de un modo inaudito. Los resultados re-significan los denominados paradigmas populares de la justicia. The present study focuses on the meaning of injustice for women from the thinking of sexual difference. The negative about household labor is studied. In response to psychosocial theory on the perception of injustice and to continue with justice knowledge, this research explores the representation of injustice for 95 women from Region of Murcia. These female participants were invited to narrate work and care in their families. It have been used several research methodologies and theories: feminist theory, Grounded theory and discursive psychology. The strongest support is for the hypothesis that suggests that women's words transcend the ordinary sense of injustice in a way unheard of. Findings give a new meaning of justice for social science

The implications of feminism for women’s social identity

La investigación psicosocial que vincula las actitudes de género y la identificación social feminista con la identidad de género es reciente. Este artículo se centra en la revisión crítica de los estudios sobre la relación entre las actitudes y la identidad social feminista. Partiendo de la teoría de la autoestima colectiva, se revisan los estudios, la metodología y las hipótesis que relacionan la identidad social de género con la identidad feminista. La representación social del feminismo aparece como un factor relevante en el proceso de identificación social. Finalmente se indican las limitaciones de estos estudios y se proponen hipótesis sobre la investigación y la relación entre la defensa del feminismo y la identificación social como feminista.Psychosocial research has only recently linked gender attitudes and the feminist social identification with gender identity. This article is a critical review of studies on feminist social identity and attitudes. Starting with the theory of collective self-esteem, the studies, the methodologies and the hypotheses that relate the social identity of gender with feminist identity are reviewed. The social representation of feminism emerges as a relevant factor in the process of social identification. Finally, certain limitations in these studies are identified and hypotheses proposed for research and the relationship between the defence of feminist ideology and the social identification as a feminist

Informe sobre la evolución y seguimiento de todos los aspectos de las soluciones basadas en la naturaleza aplicadas en Argales y Cantarias: relatório do Projeto POCTEP INDNATUR

O relatório apresentado tem o objetivo de relatar a evolução dos vários aspectos monitorizados ou analisados no início do trabalho, a fim de verificar cientificamente os efeitos das SbN implementadas nas áreas intervencionadas nas zonas industriais de Argales (Valladolid) e Cantarias (Bragança). Para alcançar o objetivo mencionado, foram realizados os seguintes estudos sobre a situação atual, tanto em Argales (Valladolid) quanto nas Cantarias (Bragança): - Medição da qualidade do ar (CO2, NOX, O3 e micropartículas) - Medição das temperaturas em espaços abertos - Avaliação da infiltração de água da chuva no subsolo - Avaliação da variação da biodiversidade Além disso, após a implementação dos corredores, foi feita uma avaliação do impacto econômico e social por meio de pesquisas específicas elaboradas a partir de documentos de referência da UE.POCTEP 0599_INDNATUR_2_Einfo:eu-repo/semantics/publishedVersio