65 research outputs found

    Long-Term Improvement in Precautions for Flood Risk Mitigation: A Case Study in the Low-Lying Area of Central Vietnam

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    Local actors appear as inseparable components of the integrated flood risk mitigation strategy in Vietnam. Recognizing this fact, this study examined the long-term improvement in precautions taken by commune authorities and households between two major floods in 1999 and 2017 by applying both quantitative and qualitative methods. Two flood-prone villages were selected for a survey; one in a rural area and the other in a suburban area of Thua Thien Hue Province, central Vietnam. The findings indicate that most villagers doubted the structural works' efficacy and were dissatisfied with the current efforts of local authorities. Households' self-preparation thus became the decisive factor in mitigating risk. While most households have paid greater attention to flood precautions in 2017, others seem to be lagging. Poverty-related barriers were the root causes restraining households in both rural and suburban villages. The suburban riverine residents were further identified as vulnerable by their limitations in upgrading structural measures, which was ascribed to the inconsistency in the ancient town's preservation policy. This multidimensional comparison, in terms of vulnerability, emphasized the importance of space-function links in the suburb and the contradictions of different policy initiatives, such as landscape rehabilitation, disaster prevention, and livelihood maintenance

    Giant compound odontoma of the mandible in an adolescent

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    Abstract Odontomas are one type of benign odontogenic hamartoma that includes the compound and complex odontoma. They are generally reported not to exceed 3 cm in diameter. Odontomas with a diameter exceeding 3 cm are considered giant odontomas. An accurate diagnosis of odontomas cannot be made during the clinical examination. The majority of compound odontoma is diagnosed most commonly during radiographic screening. It should be done in coordination with a histological examination after surgical treatment. We report a case of giant compound odontoma of the mandible in a young boy. The tumor is treated by surgical excision under general anesthesia

    Design of Mobile Manipulator for Fire Extinguisher Testing. Part I Key Specifications and Conceptual Design

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    All flames are extinguished as early as possible, or fire services have to deal with major conflagrations. This leads to the fact that the quality of fire extinguishers has become a very sensitive and important issue in firefighting. Inspired by the development of automatic fire fighting systems, this paper proposes key specifications based on the standard of fire extinguishers that is ISO 7165:2009 and ISO 11601:2008, and feasible solutions to design a mobile manipulator for automatically evaluating the quality or, more specifically, power of fire extinguishers. In addition, a part of the mechanical design is also discussed.Comment: 10 pages, 8 figures, the 7th International Conference on Advanced Engineering, Theory and Application

    Preoperative magnetic resonance imaging of anal fistulas with scrotal extension: a retrospective study

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    IntroductionThis study aimed to elucidate the magnetic resonance (MR) characteristics of anal fistulas extending to the scrotum, and the applicable rules, and to correlate MR features with surgical findings.MethodsWe conducted a retrospective study in 150 consecutive patients with anal fistulas extending into the scrotum, who were diagnosed and underwent surgery at University Medical Center Ho Chi Minh City between January 2017 and April 2022. MR findings were evaluated and compared with surgical findings using Cohens kappa coefficient (k) with a 95% confidence interval.Results150 patients (mean age 37.6 ± 10.9 years) with 166 fistulas, including 150 anal fistulas with scrotal extension. Most fistulas were low transsphincteric (80.0%, 120/150 patients). There was a strong agreement for primary tract classification and detecting the location of internal openings between MRI and surgical findings with k = 0.83 (0.780.87) and k = 0.89 (0.85 0.93) (p<0.001), respectively. There is a significant correlation between the location of internal openings and the type of fistula (p<0.05). Low transsphincteric fistulas were predominant in the anterior group (103/122 patients vs. 10/19 patients), while in the posterior group, it was more common in the high transsphincteric fistulas (7/19 patients vs. 14/122 patients), and the intersphincteric fistulas (1/19 patients vs. 5/122 patients); and the suprasphincteric fistulas were only seen in the posterior group (1 patient).ConclusionAnal fistulas with scrotal extension are exceptions to Goodsalls rule. Albeit long-tract fistulas, most are low transsphincteric and have anterior internal openings

    A Multi-Center Randomised Controlled Trial of Gatifloxacin versus Azithromycin for the Treatment of Uncomplicated Typhoid Fever in Children and Adults in Vietnam

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    BACKGROUND: Drug resistant typhoid fever is a major clinical problem globally. Many of the first line antibiotics, including the older generation fluoroquinolones, ciprofloxacin and ofloxacin, are failing. OBJECTIVES: We performed a randomised controlled trial to compare the efficacy and safety of gatifloxacin (10 mg/kg/day) versus azithromycin (20 mg/kg/day) as a once daily oral dose for 7 days for the treatment of uncomplicated typhoid fever in children and adults in Vietnam. METHODS: An open-label multi-centre randomised trial with pre-specified per protocol analysis and intention to treat analysis was conducted. The primary outcome was fever clearance time, the secondary outcome was overall treatment failure (clinical or microbiological failure, development of typhoid fever-related complications, relapse or faecal carriage of S. typhi). PRINCIPAL FINDINGS: We enrolled 358 children and adults with suspected typhoid fever. There was no death in the study. 287 patients had blood culture confirmed typhoid fever, 145 patients received gatifloxacin and 142 patients received azithromycin. The median FCT was 106 hours in both treatment arms (95% Confidence Interval [CI]; 94-118 hours for gatifloxacin versus 88-112 hours for azithromycin), (logrank test p = 0.984, HR [95% CI] = 1.0 [0.80-1.26]). Overall treatment failure occurred in 13/145 (9%) patients in the gatifloxacin group and 13/140 (9.3%) patients in the azithromycin group, (logrank test p = 0.854, HR [95% CI] = 0.93 [0.43-2.0]). 96% (254/263) of the Salmonella enterica serovar Typhi isolates were resistant to nalidixic acid and 58% (153/263) were multidrug resistant. CONCLUSIONS: Both antibiotics showed an excellent efficacy and safety profile. Both gatifloxacin and azithromycin can be recommended for the treatment of typhoid fever particularly in regions with high rates of multidrug and nalidixic acid resistance. The cost of a 7-day treatment course of gatifloxacin is approximately one third of the cost of azithromycin in Vietnam. TRIAL REGISTRATION: Controlled-Trials.com ISRCTN67946944

    Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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    Funding: F Carvalho and E Fernandes acknowledge support from Fundação para a Ciência e a Tecnologia, I.P. (FCT), in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy i4HB; FCT/MCTES through the project UIDB/50006/2020. J Conde acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325). V M Costa acknowledges the grant SFRH/BHD/110001/2015, received by Portuguese national funds through Fundação para a Ciência e Tecnologia (FCT), IP, under the Norma Transitória DL57/2016/CP1334/CT0006.proofepub_ahead_of_prin
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