Pemberian Motivasi Berwirausaha Online Kepada Siswa-siswi SMA Perguruan Advent Bogor

Toko online adalah suatu tempat kita bisa menjual, memajang, dan memperlihatkan barang dagangan diinternet. Konsep Toko online ini memungkinkan kita selaku konsumen membeli barang sesuai dengankebutuhan tanpa perlu datang ke tempat penjualnya langsung, disamping itu para pelajar diharuskan untuk dapatmengikuti perkembangan zaman dimana segala sesuatu yang rumit sudah berubah menjadi instan. Tokopediamerupakan salah satu bentuk toko online yang berhasil menarik banyak penjual dan pembeli untuk bertransaksiTujuan dari pelatihan ini adalah untuk memotivasi para pelajar untuk memahami peluang berjualan online danmampu mengimplementasikan dalam dunia nyata. Metode dilakukan dengan ceramah terhadap peserta di kelasatau ruangan tertentu dan menyampaikan materi serta tindakan nyata yang telah dilaksanakan sebelumnya dalamdunia/bisnis toko online

Pemberian Pengetahuan Sadar Pajak terhadap Siswa-siswi SMA

Pajak merupakan kontribusi wajib kepada negara yang sifatnya dapat dipaksakan dan fungsinya untukmemenuhi kebutuhan negara demi sebesar-besarnya untuk kesejahteraan masyarakat. Tanpa adanya pajakyang dipungut oleh negara, kita mungkin tidak bisa mendapatkan fasilitas umum secara mudah dantentunya murah. Untuk meningkatkan Anggaran Pendapatan Belanja Negara mulai dari usia dini diberikanpendidikan pengetahuan mengenai pajak, agar pada saat usia sudah berpenghasilan danmemiliki NomorPokok Wajib Pajak sadar untuk membayar pajak terutangnya. Untuk memotivasi para siswa-siswi,dilakukan dengan cara memberikan pelatihan di Sekolah Menengah Atas Perguruan Advent Bogor.Mempresentasikan di depan para siswa dan mengajak siswa untuk saling aktif berkomunikasi dan beranibertanya membuat semangat para siswa menjadi tinggi untuk mengetahui apa itu pajak dan kemana sajapajak itu digunakan. Dengan demikian diharapkan para siswa-siswi dapat memperoleh pengetahuan ini dantermotivasi untuk selalu sadar dan taat akan pentingnya membayar pajak dan berkontribusi untuk negara

Kajian Normatif: Pengelolaan Perbataan dan Kelembagaan Pusat-daerah Berdasarkan Rencana Induk Pengelolaan Perbatasan Negara

Penulis ingin menelaah bagaimana rentang kendali kelembagaan dari pusat ke daerah dalam mengelolawilayah perbatasan berdasarkan rencana induk pengelolaan perbatasan negara. Rencana induk pengelolaanbatas wilayah negara dan kawasan perbatasan atau Rinduk adalah rencana pembangunan nasional jangkamenengah 5 (lima) tahun yang memberikan arah kebijakan, strategi, dan program pengelolaan batas wilayahnegara dan pembangunan kawasan perbatasan yang berpedoman pada Rencana Pembangunan Jangka PanjangNasional atau RPJPN dan Rencana Pembangunan Jangka Menengah Nasional atau RPJMN. Metode penelitianpada paper ini menggunakan metode normatif, dimana secara kualitatif ditelaah berbagai regulasi yang terkaitdengan lembaga dan kelembagaan pengelola perbatasan Negara Kesatuan Republik Indonesia. Regulasimengenai kelembagaan (Badan Nasional Pengelola Perbatasan (BNPP) yang mengatur tata kelola wilayahperbatasan negara sudah ada, namun perlu penguatan kelembagaan yang lebih lagi, pelatihan sumber dayamanusia dan penyediaan dana yang dibutuhkan sesuai dengan prioritas penanganan perbatasan Negara

Pemberian Motivasi Cinta Lingkungan Kepada Siswasiswi SMA

Kerusakan kualitas lingkungan disebabkan juga oleh sistem pendidikan yang tidak memperhatikanpendidikan lingkungan terhadap anak didik sejak dini. Tujuan pengabdian kepada masyarakat ini adalahmemberikan motivasi kepada siswa-siswa SMA dalam memelihara lingkungan sejak dini. Metodologi penulisanlaporan ini adalah dengan metode deskriptif. Metode pelaksanaan diawali dengan rapat perencanaan, persiapanbahan, pelaksanaan dan evaluasi. Kegiatan pelaksanaan dilakukan dengan mengumpulkan siswa-siswi SMA dariPerguruan Advent Bogor dalam suatu kelas, lalu diberikan paparan mengapa mereka perlu mencintailingkungan demi generasi mereka sendiri. Perhatian utama yang menjadi acuan adalah lingkungan sungai,karena semua sampah pada akhirnya akan hanyut ke aliran sungai menuju laut. Pemaparan juga mengenaiSungai Citarum yang menjadi perhatian dunia karena sangat kotor dan sampai saat ini belum dapat dibersihkansecara baik. Para peserta, siswa-siswi dan guru-guru, memperhatikan dengan seksama dan banyak bertanyamengenai siapa yang bertanggung jawab mengenai kelestarian lingkungan apakah pemesrintah atau pihaklainnya. Pihak yang terutama menjaga lingkungan adalah diri sendiri agar lingkungan yang bersih dapatdinikmati secara baik sampai dengan generasi yang akan datang

Pelatihan Beriventasi Sejak Dini di Pasar Modal

Pasar Modal di Bursa Efek Indonesia (BEI) memudahkan para masyarakat untuk mengelola dananya dipasar modal. Aktivitas di BEI merupakan tempat bertemunya antara Perusahaan yang membutuhkan danadan para investor yang mempunyai dana untuk di investasikan dengan menabung saham. Pelatihan yangdilakukan di Perguruan Advent Bogor merupakan bentuk untuk mengajak Siswa-Siswi, Guru, dan WargaPerguruan Advent Bogor untuk berinvestasi sejak dini yang diprogramkan pemerintah yaitu Yuk NabungSaham. Tujuan khusus dari Pelatihan Kepada Masayarakat adalah Penyampain materi, diskusi dan simulasi.Perguruan Advent Bogor, yang terus berkelanjutan untuk ikut berperan aktif menjadi investor di BursaEfek Jakart

An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients

Background: Whilst timely clinical characterisation of infections caused by novel SARS-CoV-2 variants is necessary for evidence-based policy response, individual-level data on infecting variants are typically only available for a minority of patients and settings. Methods: Here, we propose an innovative approach to study changes in COVID-19 hospital presentation and outcomes after the Omicron variant emergence using publicly available population-level data on variant relative frequency to infer SARS-CoV-2 variants likely responsible for clinical cases. We apply this method to data collected by a large international clinical consortium before and after the emergence of the Omicron variant in different countries. Results: Our analysis, that includes more than 100,000 patients from 28 countries, suggests that in many settings patients hospitalised with Omicron variant infection less often presented with commonly reported symptoms compared to patients infected with pre-Omicron variants. Patients with COVID-19 admitted to hospital after Omicron variant emergence had lower mortality compared to patients admitted during the period when Omicron variant was responsible for only a minority of infections (odds ratio in a mixed-effects logistic regression adjusted for likely confounders, 0.67 [95% confidence interval 0.61-0.75]). Qualitatively similar findings were observed in sensitivity analyses with different assumptions on population-level Omicron variant relative frequencies, and in analyses using available individual-level data on infecting variant for a subset of the study population. Conclusions: Although clinical studies with matching viral genomic information should remain a priority, our approach combining publicly available data on variant frequency and a multi-country clinical characterisation dataset with more than 100,000 records allowed analysis of data from a wide range of settings and novel insights on real-world heterogeneity of COVID-19 presentation and clinical outcome

Liver injury in hospitalized patients with COVID-19: An International observational cohort study

Background: Using a large dataset, we evaluated prevalence and severity of alterations in liver enzymes in COVID-19 and association with patient-centred outcomes.MethodsWe included hospitalized patients with confirmed or suspected SARS-CoV-2 infection from the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) database. Key exposure was baseline liver enzymes (AST, ALT, bilirubin). Patients were assigned Liver Injury Classification score based on 3 components of enzymes at admission: Normal; Stage I) Liver injury: any component between 1-3x upper limit of normal (ULN); Stage II) Severe liver injury: any component & GE;3x ULN. Outcomes were hospital mortality, utilization of selected resources, complications, and durations of hospital and ICU stay. Analyses used logistic regression with associations expressed as adjusted odds ratios (OR) with 95% confidence intervals (CI).ResultsOf 17,531 included patients, 46.2% (8099) and 8.2% (1430) of patients had stage 1 and 2 liver injury respectively. Compared to normal, stages 1 and 2 were associated with higher odds of mortality (OR 1.53 [1.37-1.71]; OR 2.50 [2.10-2.96]), ICU admission (OR 1.63 [1.48-1.79]; OR 1.90 [1.62-2.23]), and invasive mechanical ventilation (OR 1.43 [1.27-1.70]; OR 1.95 (1.55-2.45). Stages 1 and 2 were also associated with higher odds of developing sepsis (OR 1.38 [1.27-1.50]; OR 1.46 [1.25-1.70]), acute kidney injury (OR 1.13 [1.00-1.27]; OR 1.59 [1.32-1.91]), and acute respiratory distress syndrome (OR 1.38 [1.22-1.55]; OR 1.80 [1.49-2.17]).ConclusionsLiver enzyme abnormalities are common among COVID-19 patients and associated with worse outcomes

Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study

Background: Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs). Methods: This is a multinational, multicentre, prospective cohort study embedded in the ISARIC-WHO COVID-19 Clinical Characterisation Protocol. Patients with laboratory-confirmed SARS-CoV-2 infection who required hospital admission were recruited prospectively. Patients treated with HFNC, NIV, or IMV within the first 24 h of hospital admission were included in this study. Descriptive statistics, random forest, and logistic regression analyses were used to describe clinical characteristics and compare clinical outcomes among patients treated with the different types of advanced respiratory support. Results: A total of 66,565 patients were included in this study. Overall, 82.6% of patients were treated in HIC, and 40.6% were admitted to the hospital during the first pandemic wave. During the first 24 h after hospital admission, patients in HICs were more frequently treated with HFNC (48.0%), followed by NIV (38.6%) and IMV (13.4%). In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority received IMV (59.1%). The failure rate of non-invasive respiratory support (i.e. HFNC or NIV) was 15.5%, of which 71.2% were from HIC and 28.8% from LMIC. The variables most strongly associated with non-invasive ventilation failure, defined as progression to IMV, were high leukocyte counts at hospital admission (OR [95%CI]; 5.86 [4.83-7.10]), treatment in an LMIC (OR [95%CI]; 2.04 [1.97-2.11]), and tachypnoea at hospital admission (OR [95%CI]; 1.16 [1.14-1.18]). Patients who failed HFNC/NIV had a higher 28-day fatality ratio (OR [95%CI]; 1.27 [1.25-1.30]). Conclusions: In the present international cohort, the most frequently used advanced respiratory support was the HFNC. However, IMV was used more often in LMIC. Higher leucocyte count, tachypnoea, and treatment in LMIC were risk factors for HFNC/NIV failure. HFNC/NIV failure was related to worse clinical outcomes, such as 28-day mortality. Trial registration This is a prospective observational study; therefore, no health care interventions were applied to participants, and trial registration is not applicable

Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry

Background: COVID-19 has been associated with a broad range of thromboembolic, ischemic, and hemorrhagic complications (coagulopathy complications). Most studies have focused on patients with severe disease from high-income countries (HICs). Objectives: The main aims were to compare the frequency of coagulopathy complications in developing countries (low- and middle-income countries [LMICs]) with those in HICs, delineate the frequency across a range of treatment levels, and determine associations with in-hospital mortality. Methods: Adult patients enrolled in an observational, multinational registry, the International Severe Acute Respiratory and Emerging Infections COVID-19 study, between January 1, 2020, and September 15, 2021, met inclusion criteria, including admission to a hospital for laboratory-confirmed, acute COVID-19 and data on complications and survival. The advanced-treatment cohort received care, such as admission to the intensive care unit, mechanical ventilation, or inotropes or vasopressors; the basic-treatment cohort did not receive any of these interventions. Results: The study population included 495,682 patients from 52 countries, with 63% from LMICs and 85% in the basic treatment cohort. The frequency of coagulopathy complications was higher in HICs (0.76%-3.4%) than in LMICs (0.09%-1.22%). Complications were more frequent in the advanced-treatment cohort than in the basic-treatment cohort. Coagulopathy complications were associated with increased in-hospital mortality (odds ratio, 1.58; 95% CI, 1.52-1.64). The increased mortality associated with these complications was higher in LMICs (58.5%) than in HICs (35.4%). After controlling for coagulopathy complications, treatment intensity, and multiple other factors, the mortality was higher among patients in LMICs than among patients in HICs (odds ratio, 1.45; 95% CI, 1.39-1.51). Conclusion: In a large, international registry of patients hospitalized for COVID-19, coagulopathy complications were more frequent in HICs than in LMICs (developing countries). Increased mortality associated with coagulopathy complications was of a greater magnitude among patients in LMICs. Additional research is needed regarding timely diagnosis of and intervention for coagulation derangements associated with COVID-19, particularly for limited-resource settings

Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study

Background: Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs). Methods: This is a multinational, multicentre, prospective cohort study embedded in the ISARIC-WHO COVID-19 Clinical Characterisation Protocol. Patients with laboratory-confirmed SARS-CoV-2 infection who required hospital admission were recruited prospectively. Patients treated with HFNC, NIV, or IMV within the first 24 h of hospital admission were included in this study. Descriptive statistics, random forest, and logistic regression analyses were used to describe clinical characteristics and compare clinical outcomes among patients treated with the different types of advanced respiratory support. Results: A total of 66,565 patients were included in this study. Overall, 82.6% of patients were treated in HIC, and 40.6% were admitted to the hospital during the first pandemic wave. During the first 24 h after hospital admission, patients in HICs were more frequently treated with HFNC (48.0%), followed by NIV (38.6%) and IMV (13.4%). In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority received IMV (59.1%). The failure rate of non-invasive respiratory support (i.e. HFNC or NIV) was 15.5%, of which 71.2% were from HIC and 28.8% from LMIC. The variables most strongly associated with non-invasive ventilation failure, defined as progression to IMV, were high leukocyte counts at hospital admission (OR [95%CI]; 5.86 [4.83–7.10]), treatment in an LMIC (OR [95%CI]; 2.04 [1.97–2.11]), and tachypnoea at hospital admission (OR [95%CI]; 1.16 [1.14–1.18]). Patients who failed HFNC/NIV had a higher 28-day fatality ratio (OR [95%CI]; 1.27 [1.25–1.30]). Conclusions: In the present international cohort, the most frequently used advanced respiratory support was the HFNC. However, IMV was used more often in LMIC. Higher leucocyte count, tachypnoea, and treatment in LMIC were risk factors for HFNC/NIV failure. HFNC/NIV failure was related to worse clinical outcomes, such as 28-day mortality. Trial registration This is a prospective observational study; therefore, no health care interventions were applied to participants, and trial registration is not applicable