Agen Crosslink dalam Pembuatan Biomimetic Scaffold Sebagai Material Rekayasa Jaringan Tulang

Case of bone destruction such as socket of post-tooth extraction and periodontitis can cause pain and disrupt the function of mastication, so it takes a tissue engineering material in the form of biomimetic scaffold by mimicking the structure and the original function of bone. Material for bone tissue engineering that has grown widely include the use of collagen, gelatin, chitosan, and hydroxyapatite. These materials can be mutually combined using crosslink agents in the scaffold fabrication process. Determine the role of crosslink agents in the manufacture of biomimetic scaffolds as bone tissue engineering materials in the field of dentistry. Material in the scaffold fabrication is a polymer which can be modified by the incorporation of other polymers. Additionally, polysaccharides have abundant functional groups such as hydroxyl groups, amino groups and/or carboxylic acid groups, amenable to various types of chemical modifications. Modification with other polymers can be done by adding crosslink agents by irradiation or through chemical reactions. The role of a crosslink agent in a material modification can increase the material resistance to heat, light, other physical properties, and can increase the degree of dimensional stability and mechanical strength so these values are important to consider for the survival of cells in scaffolds at early time points. Different forms of crosslink agents can be utilized to obtain good biomimetic scaffold so that optimize the osteoconductivity properties of bone tissue engineering

Harmonisasi Undang-undang Nomor 11 Tahun 2010 Tentang Cagar Budaya dan Undang-undang Nomor 19 Tahun 2002 Tentang Hak Cipta dalam Pelindungan Arsitektural Bangunan Cagar Budaya

Indonesia memiliki banyak bangunan cagar budaya bergaya arsitektur kolonial yang dibangun pada masa penjajahan Belanda. Periode masa Hindia Belanda itulah yang membedakan antara gaya bangunan masa kolonial dengan bangunan yang lain. Dimulai dari Bangunan Cagar Budaya yang bergaya arsitektur Hindis, bahkan yang merupakan perpaduan dari gaya bangunan Hindis dan tradisional. Dalam pelaksanaan pelindungan maupun pengembangan Bangunan Cagar Budaya (penelitian, revitalisasi, adaptasi) harus sesuai dengan peraturan perundang-undangan yang berlaku diantaranya adalah Undang-undang Nomor 11 Tahun 2010 tentang Cagar Budaya dan Undang-undang Nomor 19 Tahun 2002 tentang Hak Cipta maupun peraturan perundang-undangan lainnya. Sekarang ini telah banyak kegiatan pengembangan yang tidak berdasarkan peraturan perundang-undangan sehingga dalam pelaksanaannya dilakukan secara sembarangan sehingga menghilangkan nilai keaslian (orisinalitas) karya cipta arsitektur Bangunan Cagar Budaya. Dalam rangka mempertahankan gaya kearsitekturan Bangunan Cagar Budaya dan keasliannya maka selama kegiatan pelindungan dan pengembangan tidak terlepas dari pengawasan dan pemantauan oleh pemerintah agar sesuai dengan peraturan perundang-undangan yang berlaku. Dengan peran serta pemerintah dan masyarakat dalam “mengawal” kegiatan tersebut, maka keaslian Bangunan Cagar Budaya telah dijaga dan dipertahankan sesuai dengan Undang-undang Nomor 19 Tahun 2002 tentang Hak Cipta dan Undang-undang Nomor 11 Tahun 2010 tentang Cagar Budaya

PERATV MOTIVASI KERIA SEBAGAI VARIABEL PEMEDIASI DAI.AM PENGARUFT INSENTIF DENGAN PRESTASI KERIA

The purpose of this research is to f,ind correlation between insentive with work achievement and the role of insentive toward work motivation in mediating correlation between incentive with urorl< achievement. Based on the result of the research, it was found that the incentive giverr to the employees with great work achievement was in the form of money, goods, and others. Tire incentive given once a month according to the worl< achievement, which was for every unit of engine vechicle sold, the firm would give incentive as many as Rp.100.000/unit,and a reward in the form of goods or recreation. The employees' work hievements of PT. F.l.F Branch Bengkulu were influenced by incentive program given by the firm, which caused the improvement of work motivation of the employees. Incentive given by the firm is able to improve work motivation which finaly resulting the improvement of work achievement

Perbandingan Jumlah Sel Osteoblas pada Penyembuhan Luka Antara Penggunaan Kitosan Gel 1% dan 2%

The use of chitosan in medical fields known as biomaterial nowdays can be used in dental clinical application. Chitosan is obtained by N-acetylating chitin and it is a biodegradable natural biopolymer that can enhance bone healing. The aim of this study was to compare account the rate of osteoblast cells on bone healing process of dental extraction in Rattus norvegicus for 7 and 14 days. Rattus nornegicus strain wistar male, aged 8-16 weeks, divided into 3 treatment groups namely group 1 which given chitosan gel 1%, group II which given chitosan gel 2 % and group III as control which were not given chitosan gel. Chitosan were applied into the socket of dental extraction. Rat was decaputated 7 and 14 days after chitosan application and the jaw in the treated regions and control group were cut for histopatological to observe the number of osteoblast cells. Data were analyzed using t test. The result showed no significant differences in osteoblast cells number between the use chitosan gel 1 and 2 % in 7 and 14 days observation (p&lt;0,05). There was not different number of osteoblast cells with application between chitosan gel 1 % and 2 %. It can be concluded that chitosan gel 1 and 2 % has ability to enhance the bone healing process in post extraction socket of Rattus norvegicus

Moralitas dan kesadaran terhadap kepatuhan wajib pajak UMKM dengan memanfaatkan fasilitas perpajakan dimasa pandemi Covid-19

This research aims to determine the effect of morality and awareness on MSME taxpayer compliance. Based on the data obtained in Gempol District, there are 400 MSMEs. The sample is a collection of subjects that represent the population. The sampling technique used was the purposive sampling method with several criteria: 1) The business is engaged in manufacturing. 2) A business that has been around for more than 5 years. 3) MSMEs that have NPWP. Based on the criteria in determining the number of samples of 255 MSMEs that meet the criteria. So that in this case, the number of samples in the study amounted to 255 MSMEs. Multiple regression analysis tests using SPSS. The results of the study state that significantly the morality variable has a positive effect on MSME taxpayer compliance and awareness variables also affect the compliance of MSME taxpayers.

Upaya Pengembangan Kemampuan Berhitung Melalui Permainan Tradisional Dakon Kelompok B Di TK Aisyiyah Kaliwuluh Kebakkramat Karanganyar Tahun Ajaran 2012/2013

Tujuan penelitian ini adalah tujuan umum adalah untuk mengembangkan kemampuan berhitung pada anak kelompok B di TK Aisyiyah Kaliwuluh, Kebakkramat, Karanganyar Tahun ajaran 2012/2013 dan tujuan khusus adalah untuk mengetahui pengembangan kemampuan berhitung melalui permainan tradisional dakon pada anak kelompok B di TK Aisyiyah Kaliwuluh, Kebakkramat, Karanganyar Tahun ajaran 2012/2013. Jenis penelitian yang digunakan adalah penelitian tindakan (action ressearch) dengan bentuk penelitian PTK. Subjek penelitian adalah seluruh anak yang berada di Taman Kanak-Kanak Aisyiyah Kaliwuluh Kebakkramat Karanganyar tahun pelajaran 2012/2013yang berjumlah 22 siswa. Metode pengumpulan data yang dipergunakan adalah observasi partisipan, dokumentasi. Sedangkan teknik analisis data menggunakan model induktif interaktif, komponen pokok analisis induksi interaktif yaitu reduksi data, sajian data dan penarikan kesimpulan aktivitasnya dilakukan dalam bentuk interaktif dengan proses pengumpulan data sebagai suatu siklus. Berdasarkan hasil penelitian dan pembahasan dapat diketahui bahwa kemampuan berhitung anak Taman Kanak-kanak Aisyiyah Kaliwuluh Karanganyar pada siklus I dinyatakan tuntas ada 9 anak dari 22 anak (40,9 %), sedangkan yang belum tuntas ada 13 anak dari 22 anak (59,1 %). Kemampuan berhitung anak anak Taman Kanak-kanak Aisyiyah Kaliwuluh Karanganyar pada siklus II dinyatakan tuntas ada 16 anak dari 22 anak (72,7 %), sedangkan yang belum tuntas ada 6 anak dari 22 anak (27,3 %) Kemampuan berhitung pada siklus III yang dinyatakan tuntas ada 22 anak dari 22 anak (100 %), sedangkan yang belum tuntas ada 0 anak dari 22 anak (0 %). Berdasarkan keterangan di atas maka dapat dibuat suatu kesimpulan sebagai berikut: Melalui pembelajaran dengan metode bermain permainan tradisional dakon dapat mengengbangkan kemampuan berhitung anak sejak dini di Taman Kanak-kanak Aisyiyah Kaliwuluh Kebakkramat Karanganyar tahun pelajaran 2012/ 2013

Profitabilitas, likuiditas dan leverage terhadap corporate social responbility (CSR) pada perusahaan terdaftar di BEI Tahun 2017-2020

This study aims to determine the effect of profitability, liquidity and leverage on corporate social responsibility (CSR) in consumer goods industrial sector companies listed on the IDX in 2017-2020. The research data uses data on consumer goods industrial companies listed on the IDX for the 2017-2020 period. The data analysis technique of this research used multiple linear regression with statistical product and service solutions (SPSS) analysis tool. Profitability research results have no significant positive effect on the disclosure of corporate social responsibility as measured using return on assets (ROA), liquidity has a positive effect on the disclosure of corporate social responsibility (CSR) which is measured using the current ratio (CR) while when measured using the quick ratio (QR) Liquidity has a negative effect on the disclosure of corporate social responsibility. Leverage has no significant positive effect on the disclosure of corporate social responsibility as measured using the debt to asset ratio (DAR)

Strategi UMKM dalam meningkatkan pendapatan dimasa pandemi Covid-19 guna mempertahankan kelangsungan usaha di era revolusi industri 4.0 (studi pada UMKM makanan dan minuman di Kabupaten Pasuruan)

The purpose of this research is to find a strategy to increase MSME income during the COVID-19 pandemic to maintain business continuity in the era of the Industrial Revolution 4.0. The general goal is to increase the knowledge of MSME actors during the COVID-19 pandemic and increase the income of small and medium enterprises (MSMEs) for business continuity in Pasuruan Regency in the era of the Industrial Revolution 4.0. The method used in this study is a qualitative method using descriptive techniques, such as data reduction, data presentation, and concluding SWOT analysis. Informants in this survey are the Office of Cooperatives and Micro Enterprises and SMEs in Pasuruan Regency. The results showed that the Matrix Internal Factors (IFAS) and External Factors (EFAS) showed that MSMEs in the food and beverage business were located in cell V in identification, segment growth, investment choice, and specialization. The strategy that micro food and beverage businesses must be carried out in Pasuruan Regency to increase income to maintain their business in the face of the 4.0 industrial revolution. During the covid 19 pandemic, namely, on Strength Opportunity (SO), strategies used strength to take advantage of external opportunities were created.

Pengaruh Viskositas Kitosan Gel Terhadap Penggunaannya di Proses Penyembuhan Luka

Chitosan powder when dissolved with acetat acid solution gives viscous solution. The accessibility of chitosan depends on viscosity of its solution. The viscosity determines the extent of penetration of chitosan. The aim of this study was to account the proliferation cells on wound healing process of dental extraction using different viscosity of chitosan gel. Rattus nornegicus strain wistar male, aged 8-16 weeks, divided into 2 treatment groups namely group 1 which given chitosan gel with high viscosity and group II which given chitosan with low viscosity. Chitosan were applied into the socket of dental extraction. Rat was decaputated 7 and 14 days after chitosan application and the jaw in the treated regions and control group were cut for histopatological to observe the proliferation cells. Data were analyzed using t test. The result showed significant differences of proliferation cells between groups with high and low viscosity of chitosan. The group with high viscosity of chitosan have more higher of proliferation cells.(p&lt;0,05). The viscosity can influence the absorbtion of chitosan that accessibility to its application on proliferation cells of wound healing process