Self-archiving and DSpace@Cambridge

Presentation held at Unilever Centre for Molecular Science Informatics, November 12th 200

Contemporary Issues of Enterprise Content Management: The Case of Statoil

The concept of Enterprise Content Management (ECM) represents integrated enterprise-wide management of the life cycles of all forms of recorded information content and their metadata, organized according to corporate taxonomies, and supported by appropriate technological and administrative infrastructures. Based on a case study of a Norwegian oil company (Statoil) we identify a wide range of issues related to management of content, infrastructure and change. The ECM perspective is found to integrate and extend the existing research areas of information resource management and document management, as well as “the repository model” of knowledge management. ECM may thus deserve further attention beyond the current market hype as a potential area of IS research

DSpace Under the Hood: The development process and YOUR role in it

DSpace development in undertaken by the DSpace community. No one, or no organisation is in charge, and without contributions from the DSpace community the platform would not continue to develop and evolve. Sometimes it can appear that there are people in charge, or that unless you are a technical developer then there is no way or need to contribute. This presentation will explain how DSpace development usually takes place, where and who has input at different stages, and will equip you to contribute further, or to help you contribute for the first time

DSpace Under the Hood: How DSpace works

Whilst you don't need to be a mechanic to drive a car, it is helpful if you have a basic understanding of how a car works, what bits do different jobs, and how to top up your oil and pump up your tyres / tires. This presentation will give an overview of the DSpace architecture, and will give you enough knowledge to understand how DSpace works. By knowing this, you will also learn about ways DSpace could be used, and ways in which it can't be used

DSpace Under the Hood: The development process and YOUR role in it

DSpace development in undertaken by the DSpace community. No one, or no organisation is in charge, and without contributions from the DSpace community the platform would not continue to develop and evolve. Sometimes it can appear that there are people in charge, or that unless you are a technical developer then there is no way or need to contribute. This presentation will explain how DSpace development usually takes place, where and who has input at different stages, and will equip you to contribute further, or to help you contribute for the first time

DSpace Under the Hood: How DSpace works

Whilst you don't need to be a mechanic to drive a car, it is helpful if you have a basic understanding of how a car works, what bits do different jobs, and how to top up your oil and pump up your tyres / tires. This presentation will give an overview of the DSpace architecture, and will give you enough knowledge to understand how DSpace works. By knowing this, you will also learn about ways DSpace could be used, and ways in which it can't be used

Differential Expression of miRNAs in Colorectal Cancer: Comparison of Paired Tumor Tissue and Adjacent Normal Mucosa Using High-Throughput Sequencing

We present the results of a global study of dysregulated miRNAs in paired samples of normal mucosa and tumor from eight patients with colorectal cancer. Although there is existing data of miRNA contribution to colorectal tumorigenesis, these studies are typically small to medium scale studies of cell lines or non-paired tumor samples. The present study is to our knowledge unique in two respects. Firstly, the normal and adjacent tumor tissue samples are paired, thus taking into account the baseline differences between individuals when testing for differential expression. Secondly, we use high-throughput sequencing, thus enabling a comprehensive survey of all miRNAs expressed in the tissues. We use Illumina sequencing technology to perform sequencing and two different tools to statistically test for differences in read counts per gene between samples: edgeR when using the pair information and DESeq when ignoring this information, i.e., treating tumor and normal samples as independent groups. We identify 37 miRNAs that are significantly dysregulated in both statistical approaches, 19 down-regulated and 18 up-regulated. Some of these miRNAs are previously published as potential regulators in colorectal adenocarcinomas such as miR-1, miR-96 and miR-145. Our comprehensive survey of differentially expressed miRNAs thus confirms some existing findings. We have also discovered 16 dysregulated miRNAs, which to our knowledge have not previously been associated with colorectal carcinogenesis: the following significantly down-regulated miR-490-3p, -628-3p/-5p, -1297, -3151, -3163, -3622a-5p, -3656 and the up-regulated miR-105, -549, -1269, -1827, -3144-3p, -3177, -3180-3p, -4326. Although the study is preliminary with only eight patients included, we believe the results add to the present knowledge on miRNA dysregulation in colorectal carcinogenesis. As such the results would serve as a robust training set for validation of potential biomarkers in a larger cohort study. Finally, we also present data supporting the hypothesis that there are differences in miRNA expression between adenocarcinomas and neuroendocrine tumors of the colon

E-books and their future in academic libraries

Part of the book "Aspects of the Digital Library" - http://hdl.handle.net/1956/182

University of Bergen: Data exchange between national Norwegian research reporting systems and DSpace

BORA is the institutional repository of the University of Bergen. In it researchers from the University self-archive research publications such as journal articles, reports, PhD-theses and masters theses. Researchers at four of the Universities in Norway are currently reporting their research to a reporting system called FRIDA, built on the recommendations of the Ministry of Education and Research. IR project groups from the same four universities are collaborating with the FRIDA development group in Oslo to harvest data from parts of FRIDA (by using the OAI-PMH) and import these into the local IRs. They are also planning to create a solution where the researcher can upload the full-text documents (files) as well, transmitting these to the local IRs. For the Bergen Open Research Archive this means that we need to adapt DSpace to handle the imported data. They should be injected into a specialised workflow, which pools the data until staff have time to follow them up. There must also be a way to "submit" the data from the "temporary pool" into their final destination, the collections of BORA, creating traditional DSpace items

Ensuring Access to Cultural Heritage Resources

DSpace@Cambridge is the institutional repository for the University of Cambridge. It was established to facilitate both dissemination and preservation of digital materials created by members of the University. The first part of the presentation will focus on how the DSpace@Cambridge service can support the management of cultural heritage resources generated by University projects. Available approaches will be discussed, and case studies from various departments in the University will be presented. As repository services such as DSpace@Cambridge are still in their infancy, we expect to see considerable changes in the coming years. The second part of the presentation will focus on the challenges faced by DSpace@Cambridge, and will include a discussion of possible future directions for the repository