Anti-inflammatory activity of a new dipharmacophore derivative of propionic acid

This experimental laboratory animals research aimed at the anti-inflammatory activity of a new dipharmacophore derivative dexibuprofen and nebracetam when modeling an acute and chronic inflammatory reactio

Bayesian inference supports the host selection hypothesis in explaining adaptive host specificity by European bitterling

Generalist parasites have the capacity to infect multiple hosts. The temporal pattern of host specificity by generalist parasites is rarely studied, but is critical to understanding what variables underpin infection and thereby the impact of parasites on host species and the way they impose selection on hosts. Here, the temporal dynamics of infection of four species of freshwater mussel by European bitterling fish (Rhodeus amarus) was investigated over three spawning seasons. Bitterling lay their eggs in the gills of freshwater mussels, which suffer reduced growth, oxygen stress, gill damage and elevated mortality as a result of parasitism. The temporal pattern of infection of mussels by European bitterling in multiple populations was examined. Using a Bernoulli Generalized Additive Mixed Model with Bayesian inference it was demonstrated that one mussel species, Unio pictorum, was exploited over the entire bitterling spawning season. As the season progressed, bitterling showed a preference for other mussel species, which were inferior hosts. Temporal changes in host use reflected elevated density-dependent mortality in preferred hosts that were already infected. Plasticity in host specificity by bitterling conformed with the predictions of the host selection hypothesis. The relationship between bitterling and their host mussels differs qualitatively from that of avian brood parasites

"Zatesi" by V. P. Astafiev: lyrical-philosophical miniatures in the system of small forms of the "First notebook"

The article analyzes the lyrical nature of the miniature by V.P. Astafiev "The Fall of the Leaf", which is included in the Notebook under the same title of his book "Zatesi". The study is based on the works of the researchers (E.V. Kapinos, E.Y. Kulikova, A. Hansen-Loewe, etc.) of small forms of the twentieth century absorbing the properties of verse forms. The method of motif analysis used by the authors of the article allows them to reveal the features of the Sophian tradition and to show how change and correlation of various facets of the eternal feminine becomes a force organizing the lyrical plot. The authors figure out the main technique of likening man's retiring from the world to the fall of a birch leaf from the tree. Multiplicity of the shades of this state lying at the basis of the lyrical plot is revealed in the course of analysis. It is shown how Astafiev creates an image as long as eternity via reiteration, strings of homogeneous members, anaphora, and associations. The authors describe a specific character of the lyrical subject: the lyrical narrator close to the writer is depicted as able to, firstly, engulf in his inner world outer space, which allows him "to see the essential properties of existence in the bearings of the Eternity", and, secondly, be a translator of the "natural consciousness", i.e. demonstrate the features of super vision

"Zatesi" by V. P. Astafiev: lyrical-philosophical miniatures in the system of small forms of the "First notebook"

The article analyzes the lyrical nature of the miniature by V.P. Astafiev "The Fall of the Leaf", which is included in the Notebook under the same title of his book "Zatesi". The study is based on the works of the researchers (E.V. Kapinos, E.Y. Kulikova, A. Hansen-Loewe, etc.) of small forms of the twentieth century absorbing the properties of verse forms. The method of motif analysis used by the authors of the article allows them to reveal the features of the Sophian tradition and to show how change and correlation of various facets of the eternal feminine becomes a force organizing the lyrical plot. The authors figure out the main technique of likening man's retiring from the world to the fall of a birch leaf from the tree. Multiplicity of the shades of this state lying at the basis of the lyrical plot is revealed in the course of analysis. It is shown how Astafiev creates an image as long as eternity via reiteration, strings of homogeneous members, anaphora, and associations. The authors describe a specific character of the lyrical subject: the lyrical narrator close to the writer is depicted as able to, firstly, engulf in his inner world outer space, which allows him "to see the essential properties of existence in the bearings of the Eternity", and, secondly, be a translator of the "natural consciousness", i.e. demonstrate the features of super vision

When and why formation of large bodies in circumstellar discs could take place?

We outlined the scenario of the planetary system formation, where large bodies are formed on the stage of massive discs. On this stage the whole of factors: chemical composition, chemical catalytic reactions, the disc self- gravitation, the increased ratio of solids to gas surface density, adiabatic gas cooling provides favorable conditions for gravitational instabilities development. Gravitational instabilities in multiphase medium can lead to planetesimal and planetary embryo formation

Вплив активності мастильного середовища на трибохімічну зносостійкість композиційних покриттів

Проаналізовано вплив активності мастильного середовища на трибохімічну зносостійкість композиційних покриттів під час зміни швидкості ковзання та питомого навантаження вузлів тертя авіаційної технік

A study of Pt/al2O3 nanocomposites obtained by pulsed laser ablation to be used as catalysts of oxidation reactions

Pulsed laser ablation (PLA) in liquids is an effective high-energy method for the synthesis of functional nanomaterials. In the present work, a nanocomposite catalyst Pt/Al2O3(PLA) is prepared by mixing solutions of platinum and aluminium nanodispersions obtained by the PLA method in alcohol and water, respectively. After being dried out, the obtained nanocomposite is thermally treated in air at 400 °C and 550 °C. It is shown by X-ray photoelectron spectroscopy (XPS) and X-ray diffraction that platinum in the composition of the calcined samples stabilizes on the Al2O3 surface in the form of metal nanoparticles. The main crystal structure of η-Al2O3 is determined and impurity phases of Al(OH)3 hydroxide and metallic aluminium are revealed using X-ray powder diffraction (XRPD). The Pt/Al2O3 nanocomposite samples obtained by the PLA method are found to be highly prospective for the use in reactions of catalytic oxidation of CO and NH3. The Pt/Al2O3(PLA) nanocomposites are compared with the Pt/Al2O3 (IMP) catalyst synthesized by the method of solution chemistry. The Pt/Al2O3(IMP) sample containing highly dispersed platinum nanoparticles (1–2 nm) on the γ-Al2O3 surface has a lower T50 value (188 °C) in the reaction of CO oxidation that the PLA catalyst (T50 = 198 °C). At the same time, in the reaction of NH3 oxidation, the PLA catalyst is more active (T50 = 167 °C) than the IMP sample (T50 = 180 °C). The observed regularities are discussed in terms of the dispersion and the oxidation depth of platinum particles in the composition of Pt/Al2O3 catalysts