Utilizing Self-Determination Theory in Teaching the Research and Evaluation Course

Research is an important component in counselor preparation. However, students often are not motivated in taking the research course. The author explores and applies the Self-Determination Theory (SDT; Ryan & Deci, 2000) to teaching the research and evaluation course. Self-Determination Theory posits that student will be autonomously motivated to learn when basic needs of autonomy, relatedness, and competence are present in the classroom. Strategies to increase all three basic needs are discussed in this paper

Analysis of Toxic Amyloid Fibril Interactions at Natively Derived Membranes by Ellipsometry

There is an ongoing debate regarding the culprits of cytotoxicity associated with amyloid disorders. Although small pre-fibrillar amyloid oligomers have been implicated as the primary toxic species, the fibrillar amyloid material itself can also induce cytotoxicity. To investigate membrane disruption and cytotoxic effects associated with intact and fragmented fibrils, the novel in situ spectroscopic technique of Total Internal Reflection Ellipsometry (TIRE) was used. Fibril lipid interactions were monitored using natively derived whole cell membranes as a model of the in vivo environment. We show that fragmented fibrils have an increased ability to disrupt these natively derived membranes by causing a loss of material from the deposited surface when compared with unfragmented fibrils. This effect was corroborated by observations of membrane disruption in live cells, and by dye release assay using synthetic liposomes. Through these studies we demonstrate the use of TIRE for the analysis of protein-lipid interactions on natively derived lipid surfaces, and provide an explanation on how amyloid fibrils can cause a toxic gain of function, while entangled amyloid plaques exert minimal biological activity

The Effects of Shoulder and Knee Angular Velocity on the Performance of a Volleyball Forearm Pass

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Taking into account the quality of the relationship in HIV disclosure

Despite growing interest in HIV disclosure, most theoretical frameworks and empirical studies focus on individual and social factors affecting the process, leaving the contribution of interpersonal factors relatively unexplored. HIV transmission and disclosure often occur within a couple however, and this is where disclosure has the most scope as a HIV transmission intervention. With this in mind, this study explores whether perceived relationship quality influences HIV disclosure outcomes. Ninety-five UK individuals with HIV participated in a cross-sectional survey. Retrospective data were collected on their perceived relationship quality prior to disclosing their HIV positive status, and on disclosure outcomes. Perceived relationship quality was found to significantly affect disclosure outcomes. Positive qualities in the relationship were associated with positive outcomes, whereas negative qualities were associated with negative outcomes. Results further confirmed that this association was not merely correlational, but demonstrated predictive power. Relationship quality might act as either a risk or a resilience factor in the disclosure process, and thus warrants greater attention in future research

Drosophila OBP LUSH Is Required for Activity of Pheromone-Sensitive Neurons

AbstractOdorant binding proteins (OBPs) are extracellular proteins localized to the chemosensory systems of most terrestrial species. OBPs are expressed by nonneuronal cells and secreted into the fluid bathing olfactory neuron dendrites. Several members have been shown to interact directly with odorants, but the significance of this is not clear. We show that the Drosophila OBP lush is completely devoid of evoked activity to the pheromone 11-cis vaccenyl acetate (VA), revealing that this binding protein is absolutely required for activation of pheromone-sensitive chemosensory neurons. lush mutants are also defective for pheromone-evoked behavior. Importantly, we identify a genetic interaction between lush and spontaneous activity in VA-sensitive neurons in the absence of pheromone. The defects in spontaneous activity and VA sensitivity are reversed by germline transformation with a lush transgene or by introducing recombinant LUSH protein into mutant sensilla. These studies directly link pheromone-induced behavior with OBP-dependent activation of a subset of olfactory neurons

Combined effects of fatigue indicators on the health and wellbeing of workers in the offshore oil industry

Offshore workers are exposed to a unique combination of factors that may impact negatively on well-being. This paper describes results from a survey of fatigue, health and injury amongst seafarers and installation personnel working in the UK sector of the offshore oil industry. Potential stressors and fatigue­ related variables (e.g. noise, working hours, and shift) were considered in terms of their combined effects on subjective outcome measures. Median splits of these variables were summed to create a 'total fatigue indicators' score. A quartile split of this variable was entered into a series of analyses of covariance (ANCOVA), co-varying age, education and socio-economic status (SES) and stratifying for occupational group (i.e. seafarers or installation personnel). Total fatigue indicators demonstrated a linear effect on depression, cognitive failures, social functioning, lack of/poor quality sleep, fatigue, and the home-work interface. Effects were more pronounced amongst installation personnel than seafarers. This is possibly due to fundamental differences in shift systems between the two groups of offshore workers. No significant effects were observed for injury frequency, prescribed medication or smoking and alcohol consumption. Results suggest that exposure to a combination of stressors has a significantly greater negative effect on health than any of these factors in isolation

An algorithm for the direct reconstruction of the dark matter correlation function from weak lensing and galaxy clustering

The clustering of matter on cosmological scales is an essential probe for studying the physical origin and composition of our Universe. To date, most of the direct studies have focused on shear-shear weak lensing correlations, but it is also possible to extract the dark matter clustering by combining galaxy-clustering and galaxy-galaxy-lensing measurements. In this study we develop a method that can constrain the dark matter correlation function from galaxy clustering and galaxy-galaxy-lensing measurements, by focusing on the correlation coefficient between the galaxy and matter overdensity fields. To generate a mock galaxy catalogue for testing purposes, we use the Halo Occupation Distribution approach applied to a large ensemble of N-body simulations to model pre-existing SDSS Luminous Red Galaxy sample observations. Using this mock catalogue, we show that a direct comparison between the excess surface mass density measured by lensing and its corresponding galaxy clustering quantity is not optimal. We develop a new statistic that suppresses the small-scale contributions to these observations and show that this new statistic leads to a cross-correlation coefficient that is within a few percent of unity down to 5 Mpc/h. Furthermore, the residual incoherence between the galaxy and matter fields can be explained using a theoretical model for scale-dependent bias, giving us a final estimator that is unbiased to within 1%. We also perform a comprehensive study of other physical effects that can affect the analysis, such as redshift space distortions and differences in radial windows between galaxy clustering and weak lensing observations. We apply the method to a range of cosmological models and show the viability of our new statistic to distinguish between cosmological models.Comment: 23 pages, 14 figures, accepted by PRD; minor changes to V1, 1 new figure, more detailed discussion of the covariance of the new ADSD statisti

Parents' perceived obstacles to pediatric clinical trial participation: Findings from the clinical trials transformation initiative.

Enrollment of children into pediatric clinical trials remains challenging. More effective strategies to improve recruitment of children into trials are needed. This study used in-depth qualitative interviews with parents who were approached to enroll their children in a clinical trial in order to gain an understanding of the barriers to pediatric clinical trial participation. Twenty-four parents whose children had been offered the opportunity to participate in a clinical trial were interviewed: 19 whose children had participated in at least 1 clinical trial and 5 who had declined participation in any trial. Each study aspect, from the initial explanation of the study to the end of the study, can affect the willingness of parents to consent to the proposed study and future studies. Establishing trust, appropriate timing, a transparent discussion of risks and benefits oriented to the layperson, and providing motivation for children to participate were key factors that impacted parents' decisions. In order for clinical trial accrual to be successful, parents' priorities and considerations must be a central focus, beginning with initial trial design. The recommendations from the parents who participated in this study can be used to support budget allocations that ensure adequate training of study staff and improved staffing on nights and weekends. Studies of parent responses in outpatient settings and additional inpatient settings will provide valuable information on the consent process from the child's and parent's perspectives. Further studies are needed to explore whether implementation of such strategies will result in improved recruitment for pediatric clinical trials

The COBE DIRBE Point Source Catalog

We present the COBE DIRBE Point Source Catalog, an all-sky catalog containing infrared photometry in 10 bands from 1.25 microns to 240 microns for 11,788 of the brightest near and mid-infrared point sources in the sky. Since DIRBE had excellent temporal coverage (100 - 1900 independent measurements per object during the 10 month cryogenic mission), the Catalog also contains information about variability at each wavelength, including amplitudes of variation observed during the mission. Since the DIRBE spatial resolution is relatively poor (0.7 degrees), we have carefully investigated the question of confusion, and have flagged sources with infrared-bright companions within the DIRBE beam. In addition, we filtered the DIRBE light curves for data points affected by companions outside of the main DIRBE beam but within the `sky' portion of the scan. At high Galactic latitudes (|b| > 5 degrees), the Catalog contains essentially all of the unconfused sources with flux densities greater than 90, 60, 60, 50, 90, and 165 Jy at 1.25, 2.2, 3.5, 4.9, 12, and 25 microns, respectively, corresponding to magnitude limits of approximately 3.1, 2.6, 1.7, 1.3, -1.3, and -3.5. At longer wavelengths and in the Galactic Plane, the completeness is less certain because of the large DIRBE beam and possible contributions from extended emission. The Catalog also contains the names of the sources in other catalogs, their spectral types, variability types, and whether or not the sources are known OH/IR stars. We discuss a few remarkable objects in the Catalog. [abridged]Comment: Accepted for publication in the Astrophysical Journal Supplement. The full tables are available at http://www.etsu.edu/physics/bsmith/dirbe

Dipole-Dipole Interaction Between Rubidium Rydberg Atoms

Ultracold Rydberg atoms in a static electric field can exchange energy via the dipole-dipole interaction. The Stark effect shifts the energy levels of the atoms which tunes the energy exchange into resonance at specific values of the electric field (F¨orster resonances). We excite rubidium atoms to Rydberg states by focusing either a 480 nm beam from a tunable dye laser or a pair of diode lasers into a magneto-optical trap. The trap lies at the center of a configuration of electrodes. We scan the electric field by controlling the voltage on the electrodes while measuring the fraction of atoms that interact. Dipole-dipole interaction spectra are presented for initially excited rubidium nd states for n = 31 to 46 and for four different pairs of initially excited rubidium ns states. We also present the dipole-dipole interaction spectra for individual rubidium 32d (j,mj ) fine structure levels that have been selectively excited. The data are compared to calculated spectra