3,188 research outputs found
How equal is equality? Discussions about same-sex marriage in Portugal
In Portugal, public and political discussions about same-sex marriage have been going on since the 1990s. In 2010, same-sex marriage was legalized under intense dispute since it excludes same-sex couples from adoption and reproductive rights. During parliamentary debates, political parties and civil organizations linked to the Catholic Church resorted to conflicting ideas of ‘equality’ and ‘difference’ to advance their claims. In this article, we analyse the contents of petitions, bills and parliamentary proceedings concerning the legal recognition of same-sex unions, highlighting the presence of conflicting notions of equality linked to pervasive beliefs about the inadequacy of homo-erotic desire and practices
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Evolução na utilização e nos gastos de uma operadora de saúde
Brazil’s aging population and the rising number of people reliant upon the country’s supplementary healthcare system have elicited the concern of public and private managers regarding the increase in healthcare costs. In this paper, the costs per gender, per type of medical expenses and per age group of a major Brazilian self-managed healthcare provider between 2007 and 2013 were analyzed. This healthcare provider is of interest because, besides portraying a single condition of revenue growth restricted to the existing contributors, it also replicates the demographic profile expected for Brazil in 2050, when approximately one-third of its population will be over 60 years of age. The analyses confirm the current literature as they show an increase in healthcare plan usage by the elderly and the difference between admission rates by gender. They also reveal an increase in average length of stay in hospital and the increase in medical costs far above inflation, especially for materials and medicines. It is hoped that this study will help scholars and others interested in comparisons of medical expense trends, especially by age and sex, and that it encourages further collaboration on the sustainability of health insurance providers in Brazil
Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus
Postmilking teat disinfection is one of the main measures used to prevent mastitis caused by contagious pathogens, such as Staphylococcus aureus. The present study evaluated the antimicrobial activity of polyhexamethylene biguanide (PHMB) and PHMB nanoparticles (NP) against mastitis-causing Staph. aureus using a microdilution assay methodology. A total of 20 mastitis-causing Staph. aureus isolates were used to determine the minimum inhibitory concentrations (MIC) of PHMB and PHMB NP compared with 3 disinfectants commonly used for teat disinfection (chlorhexidine digluconate, povidone-iodine, and sodium dichloroisocyanurate). The MIC90 was defined at the concentrations required to inhibit the growth of 90% of Staph. aureus. Our results indicated that PHMB NP presented the lowest MIC value (<0.03 µg/mL) to inhibit 90% of Staph. aureus, followed by chlorhexidine digluconate (≥0.25 µg/mL) and PHMB (≥0.5 µg/mL). On the other hand, sodium dichloroisocyanurate (≥500 µg/mL) and povidone-iodine (≥8,000 µg/mL) presented the highest concentrations to inhibit the growth of most Staph. aureus. Our preliminary results suggested that both PHMB and PHMB NP have antimicrobial activity against mastitis-causing Staph. aureus, which indicates the potential for both to be used as a teat-dip disinfectant to prevent bovine mastitis
Motion-Guided Masking for Spatiotemporal Representation Learning
Several recent works have directly extended the image masked autoencoder
(MAE) with random masking into video domain, achieving promising results.
However, unlike images, both spatial and temporal information are important for
video understanding. This suggests that the random masking strategy that is
inherited from the image MAE is less effective for video MAE. This motivates
the design of a novel masking algorithm that can more efficiently make use of
video saliency. Specifically, we propose a motion-guided masking algorithm
(MGM) which leverages motion vectors to guide the position of each mask over
time. Crucially, these motion-based correspondences can be directly obtained
from information stored in the compressed format of the video, which makes our
method efficient and scalable. On two challenging large-scale video benchmarks
(Kinetics-400 and Something-Something V2), we equip video MAE with our MGM and
achieve up to + improvement compared to previous state-of-the-art
methods. Additionally, our MGM achieves equivalent performance to previous
video MAE using up to fewer training epochs. Lastly, we show that MGM
generalizes better to downstream transfer learning and domain adaptation tasks
on the UCF101, HMDB51, and Diving48 datasets, achieving up to +
improvement compared to baseline methods.Comment: Accepted to ICCV 202
MEGA: Multimodal Alignment Aggregation and Distillation For Cinematic Video Segmentation
Previous research has studied the task of segmenting cinematic videos into
scenes and into narrative acts. However, these studies have overlooked the
essential task of multimodal alignment and fusion for effectively and
efficiently processing long-form videos (>60min). In this paper, we introduce
Multimodal alignmEnt aGgregation and distillAtion (MEGA) for cinematic
long-video segmentation. MEGA tackles the challenge by leveraging multiple
media modalities. The method coarsely aligns inputs of variable lengths and
different modalities with alignment positional encoding. To maintain temporal
synchronization while reducing computation, we further introduce an enhanced
bottleneck fusion layer which uses temporal alignment. Additionally, MEGA
employs a novel contrastive loss to synchronize and transfer labels across
modalities, enabling act segmentation from labeled synopsis sentences on video
shots. Our experimental results show that MEGA outperforms state-of-the-art
methods on MovieNet dataset for scene segmentation (with an Average Precision
improvement of +1.19%) and on TRIPOD dataset for act segmentation (with a Total
Agreement improvement of +5.51%)Comment: ICCV 2023 accepte
Effect of somatic cell count on Prato cheese composition
The objective of this research was to evaluate the effect of 2 levels of somatic cell counts (SCC) in raw milk on Prato cheese composition, protein and fat recovery, cheese yield, and ripening. A 2 x 6 factorial design with 3 replications was performed in this study: 2 levels of SCC and 6 levels of storage time. Initially, 2 groups of dairy cows were selected to obtain low ( 600,000 cells/mL) SCC in milks that were used to manufacture 2 vats of cheese: 1) low SCC and 2) high SCC. Milk, whey, and cheese compositions were evaluated; clotting time was measured; and cheese yield, protein recovery, and fat recovery were calculated. The cheeses were evaluated after 5, 12, 19, 26, 33, and 40 d of ripening according to pH, moisture, pH 4.6 soluble nitrogen, 12% trichloroacetic acid soluble nitrogen as a percentage of total nitrogen, and firmness. High-SCC milk presented significantly higher total protein and nonprotein nitrogen and lower true protein and casein concentrations than did low-SCC milk, indicating an increased whey protein content and a higher level of proteolysis. Although the pH of the milk was not affected by the somatic cell level, the cheese obtained from high-SCC milk presented significantly higher pH values during manufacture and a higher clotting time. No significant differences in cheese yield and protein recovery were observed for these levels of milk somatic cells. The cheese from high-SCC milk was higher in moisture and had a higher level of proteolysis during ripening, which could compromise the typical sensory quality of the product.90263063
A Comprehensive Societal Energy Return on Investment Study of Portugal Reveals a Low but Stable Value
Energy return on investment (EROI) is a ratio of the energy obtained in relation to the energy used to extract/produce it. The EROI of fossil fuels is globally decreasing. What do the declining EROIs of energy sources imply for society as a whole? We answer this question by proposing a novel EROI measure that describes, through one parameter, the efficiency of a society in managing energy resources over time. Our comprehensive societal EROI measure was developed by (1) expanding the boundaries of the analysis up to the useful stage; (2) estimating the amount of energy embodied in the energy-converting capital; (3) considering non-conventional sources such as the muscle work of humans and draught animals; and (4) considering the influence of imported and exported energy. We computed the new EROI for Portugal as a case study. We find a considerably lower EROI value, at around 3, compared to those currently available, which is stable over a long-time range (1960–2014). This suggests an independence of EROI from economic growth. When estimated at the final stage, using conventional methods (i.e., without applying the four novelties here introduced), we find a declining societal EROI. Therefore, our results imply that the production of new and more efficient final-to-useful energy converting capital has historically kept societal EROI around a stable value by offsetting the effects of the changing returns of energy sources at the primary and final stages. This will be crucial in the successful transition to renewables
Exploiting Term Hiding to Reduce Run-time Checking Overhead
One of the most attractive features of untyped languages is the flexibility
in term creation and manipulation. However, with such power comes the
responsibility of ensuring the correctness of these operations. A solution is
adding run-time checks to the program via assertions, but this can introduce
overheads that are in many cases impractical. While static analysis can greatly
reduce such overheads, the gains depend strongly on the quality of the
information inferred. Reusable libraries, i.e., library modules that are
pre-compiled independently of the client, pose special challenges in this
context. We propose a technique which takes advantage of module systems which
can hide a selected set of functor symbols to significantly enrich the shape
information that can be inferred for reusable libraries, as well as an improved
run-time checking approach that leverages the proposed mechanisms to achieve
large reductions in overhead, closer to those of static languages, even in the
reusable-library context. While the approach is general and system-independent,
we present it for concreteness in the context of the Ciao assertion language
and combined static/dynamic checking framework. Our method maintains the full
expressiveness of the assertion language in this context. In contrast to other
approaches it does not introduce the need to switch the language to a (static)
type system, which is known to change the semantics in languages like Prolog.
We also study the approach experimentally and evaluate the overhead reduction
achieved in the run-time checks.Comment: 26 pages, 10 figures, 2 tables; an extension of the paper version
accepted to PADL'18 (includes proofs, extra figures and examples omitted due
to space reasons
Widespread environmental contamination with Mycobacterium tuberculosis complex revealed by a molecular detection protocol
Environmental contamination with Mycobacterium tuberculosis complex (MTC) has been considered crucial for bovine tuberculosis persistence in multi-host-pathogen systems. However, MTC contamination has been difficult to detect due to methodological issues. In an attempt to overcome this limitation we developed an improved protocol for the detection of MTC DNA. MTC DNA concentration was estimated by the Most Probable Number (MPN) method. Making use of this protocol we showed that MTC contamination is widespread in different types of environmental samples from the Iberian Peninsula, which supports indirect transmission as a contributing mechanism for the maintenance of bovine tuberculosis in this multi-host-pathogen system. The proportion of MTC DNA positive samples was higher in the bovine tuberculosis-infected than in presumed negative area (0.32 and 0.18, respectively). Detection varied with the type of environmental sample and was more frequent in sediment from dams and less frequent in water also from dams (0.22 and 0.05, respectively). The proportion of MTC-positive samples was significantly higher in spring (p<0.001), but MTC DNA concentration per sample was higher in autumn and lower in summer. The average MTC DNA concentration in positive samples was 0.82 MPN/g (CI95 0.70-0.98 MPN/g). We were further able to amplify a DNA sequence specific of Mycobacterium bovis/caprae in 4 environmental samples from the bTB-infected area
The application of Bonelike® Poro as a synthetic bone substitute for the management of critical-sized bone defects - A comparative approach to the autograft technique - A preliminary study
The effective treatment of non-unions and critical-sized defects remains a challenge in the orthopedic field. From a tissue engineering perspective, this issue can be addressed through the application bioactive matrixes to support bone regeneration, such as Bonelike®, as opposed to the widespread autologous grafting technique. An improved formulation of Bonelike® Poro, was assessed as a synthetic bone substitute in an ovine model for critical-sized bone defects. Bone regeneration was assessed after 5 months of recovery through macro and microscopic analysis of the healing features of the defect sites. Both the application of natural bone graft or Bonelike® Poro resulted in bridging of the defects margins. Untreated defect remained as fibrous non-unions at the end of the study period. The characteristics of the newly formed bone and its integration with the host tissue were assessed through histomorphometric and histological analysis, which demonstrated Bonelike® Poro to result in improved healing of the defects. The group treated with synthetic biomaterial presented bone bridges of increased thickness and bone features that more closely resembled the native spongeous and cortical bone. The application of Bonelike® Poro enabled the regeneration of critical-sized lesions and performed comparably to the autograph technique, validating its octeoconductive and osteointegrative potential for clinical application as a therapeutic strategy in human and veterinary orthopedics.This research was supported by Projects PEst-OE/AGR/UI0211/2011 from FCT , and COMPETE 2020 , from ANI – Projetos ID&T Empresas em Copromoção , by the project “insitu.Biomas – Reinvent biomanufacturing systems by using an usability approach for in situ clinic temporary implants fabrication” with the reference POCI-01-0247-FEDER-017771 , by the project “Print-on-Organs – Engineering bioinks and processes for direct printing on organs” with the reference POCI-01-0247-FEDER-033877 , and by the project “Bone2Move - Development of ‘in vivo’ experimental techniques and modelling methodologies for the evaluation of 4D scaffolds for bone defect in sheep model: an integrative research approach” with the reference POCI-01-0145-FEDER-031146 . Mariana Vieira Branquinho ( SFRH/BD/146172/2019 ), Ana Catarina Sousa ( SFRH/BD/146689/2019 ), and Rui Damásio Alvites ( SFRH/BD/116118/2016 ), acknowledge FCT , for financial support.
This research was supported by Projects PEst-OE/AGR/UI0211/2011 from FCT, and COMPETE 2020, from ANI ? Projetos ID&T Empresas em Copromo??o, by the project ?insitu.Biomas ? Reinvent biomanufacturing systems by using an usability approach for in situ clinic temporary implants fabrication? with the reference POCI-01-0247-FEDER-017771, by the project ?Print-on-Organs ? Engineering bioinks and processes for direct printing on organs? with the reference POCI-01-0247-FEDER-033877, and by the project ?Bone2Move - Development of ?in vivo? experimental techniques and modelling methodologies for the evaluation of 4D scaffolds for bone defect in sheep model: an integrative research approach? with the reference POCI-01-0145-FEDER-031146. Mariana Vieira Branquinho (SFRH/BD/146172/2019), Ana Catarina Sousa (SFRH/BD/146689/2019), and Rui Dam?sio Alvites (SFRH/BD/116118/2016), acknowledge FCT, for financial support
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