8 research outputs found
El juego como principal herramienta para la motricidad gruesa en el grupo de preescolar
Zambrano (2013) nos comenta que la motricidad gruesa se describe como la capacidad de los niños para dominar los movimientos de su cuerpo y expresarse a través de diferentes habilidades, según la etapa en que se encuentren. El presente documento está encauzado a favorecer la motricidad gruesa de los niños de tercero de preescolar, mediante juegos y actividades que se aplicaron en el grupo para impactar directamente en la motricidad gruesa, en el cual se estuvo a cargo durante este ciclo escolar. López (2001) explica que las habilidades motrices de los niños a desarrollar son las que se refieren al conocimiento y dominio de su propio cuerpo, como el esquema corporal, control y ajuste postural, respiración y relajación; las relacionadas con locomoción son saltos y desplazamientos; la manipulación como: lanzamientos y recepciones; las referidas a los giros, habilidades genéricas (botes, conducciones y golpeteos), a la progresiva conquista del medio espacial y temporal. La actividad lúdica es innata en los pequeños, pues es lo que más les gusta hacer, se considera necesaria para los seres humanos teniendo suma importancia en la sociedad, pues permite experimentar ciertas conductas sociales; siendo, a su vez, una herramienta útil para desarrollar capacidades intelectuales, motoras o afectivas (Bello,1990)
Perfil de índice de masa corporal (imc) en un grupo de niños de edades escolares
Durante los últimos veinticinco años, la obesidad pasa a ser un problema de proporciones epidemiológica tanta en adultos como en niños...
Consumo de ácido grasos en universitarios y su relación con su porcentaje de masa grasa
La alimentación es uno de los factores que más condiciona la salud de los individuos, ejerciendo un papel primordial sobre el desarrollo físico y el crecimiento, la reproducción y el rendimiento físico e intelectual ..
Time to Switch to Second-line Antiretroviral Therapy in Children With Human Immunodeficiency Virus in Europe and Thailand.
Background: Data on durability of first-line antiretroviral therapy (ART) in children with human immunodeficiency virus (HIV) are limited. We assessed time to switch to second-line therapy in 16 European countries and Thailand. Methods: Children aged <18 years initiating combination ART (≥2 nucleoside reverse transcriptase inhibitors [NRTIs] plus nonnucleoside reverse transcriptase inhibitor [NNRTI] or boosted protease inhibitor [PI]) were included. Switch to second-line was defined as (i) change across drug class (PI to NNRTI or vice versa) or within PI class plus change of ≥1 NRTI; (ii) change from single to dual PI; or (iii) addition of a new drug class. Cumulative incidence of switch was calculated with death and loss to follow-up as competing risks. Results: Of 3668 children included, median age at ART initiation was 6.1 (interquartile range (IQR), 1.7-10.5) years. Initial regimens were 32% PI based, 34% nevirapine (NVP) based, and 33% efavirenz based. Median duration of follow-up was 5.4 (IQR, 2.9-8.3) years. Cumulative incidence of switch at 5 years was 21% (95% confidence interval, 20%-23%), with significant regional variations. Median time to switch was 30 (IQR, 16-58) months; two-thirds of switches were related to treatment failure. In multivariable analysis, older age, severe immunosuppression and higher viral load (VL) at ART start, and NVP-based initial regimens were associated with increased risk of switch. Conclusions: One in 5 children switched to a second-line regimen by 5 years of ART, with two-thirds failure related. Advanced HIV, older age, and NVP-based regimens were associated with increased risk of switch
Factors associated with the severity of COVID-19 outcomes in people with neuromuscular diseases: Data from the International Neuromuscular COVID-19 Registry.
Prevalence and Clinical Outcomes of Poor Immune Response Despite Virologically Suppressive Antiretroviral Therapy Among Children and Adolescents With Human Immunodeficiency Virus in Europe and Thailand: Cohort Study
International audienceIn human immunodeficiency virus (HIV)-positive adults, low CD4 cell counts despite fully suppressed HIV-1 RNA on antiretroviral therapy (ART) have been associated with increased risk of morbidity and mortality. We assessed the prevalence and outcomes of poor immune response (PIR) in children receiving suppressive ART
Prevalence and Clinical Outcomes of Poor Immune Response Despite Virologically Suppressive Antiretroviral Therapy Among Children and Adolescents With Human Immunodeficiency Virus in Europe and Thailand: Cohort Study
BACKGROUND: In human immunodeficiency virus (HIV)-positive adults, low CD4 cell counts despite fully suppressed HIV-1 RNA on antiretroviral therapy (ART) have been associated with increased risk of morbidity and mortality. We assessed the prevalence and outcomes of poor immune response (PIR) in children receiving suppressive ART. METHODS: Sixteen cohorts from the European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) contributed data. Children <18 years at ART initiation, with sustained viral suppression (VS) (≤400 copies/mL) for ≥1 year were included. The prevalence of PIR (defined as World Health Organization advanced/severe immunosuppression for age) at 1 year of VS was described. Factors associated with PIR were assessed using logistic regression. Rates of acquired immunodeficiency syndrome (AIDS) or death on suppressive ART were calculated by PIR status. RESULTS: Of 2318 children included, median age was 6.4 years and 68% had advanced/severe immunosuppression at ART initiation. At 1 year of VS, 12% had PIR. In multivariable analysis, PIR was associated with older age and worse immunological stage at ART start, hepatitis B coinfection, and residing in Thailand (all P ≤ .03). Rates of AIDS/death (95% confidence interval) per 100 000 person-years were 1052 (547, 2022) among PIR versus 261 (166, 409) among immune responders; rate ratio of 4.04 (1.83, 8.92; P < .001). CONCLUSIONS: One in eight children in our cohort experienced PIR despite sustained VS. While the overall rate of AIDS/death was low, children with PIR had a 4-fold increase in risk of event as compared with immune responders