Model term selection for spatio-temporal system identification using mutual information

A new mutual information based algorithm is introduced for term selection in spatio-temporal models. A generalised cross validation procedure is also introduced for model length determination and examples based on cellular automata, coupled map lattice and partial differential equations are described

Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epithelia

<p>Background Comparative analysis of tissue-specific transcriptomes is a powerful technique to uncover tissue functions. Our FlyAtlas.org provides authoritative gene expression levels for multiple tissues of Drosophila melanogaster (1). Although the main use of such resources is single gene lookup, there is the potential for powerful meta-analysis to address questions that could not easily be framed otherwise. Here, we illustrate the power of data-mining of FlyAtlas data by comparing epithelial transcriptomes to identify a core set of highly-expressed genes, across the four major epithelial tissues (salivary glands, Malpighian tubules, midgut and hindgut) of both adults and larvae.</p> <p>Method Parallel hypothesis-led and hypothesis-free approaches were adopted to identify core genes that underpin insect epithelial function. In the former, gene lists were created from transport processes identified in the literature, and their expression profiles mapped from the flyatlas.org online dataset. In the latter, gene enrichment lists were prepared for each epithelium, and genes (both transport related and unrelated) consistently enriched in transporting epithelia identified.</p> <p>Results: A key set of transport genes, comprising V-ATPases, cation exchangers, aquaporins, potassium and chloride channels, and carbonic anhydrase, was found to be highly enriched across the epithelial tissues, compared with the whole fly. Additionally, a further set of genes that had not been predicted to have epithelial roles, were co-expressed with the core transporters, extending our view of what makes a transporting epithelium work. Further insights were obtained by studying the genes uniquely overexpressed in each epithelium; for example, the salivary gland expresses lipases, the midgut organic solute transporters, the tubules specialize for purine metabolism and the hindgut overexpresses still unknown genes.</p> <p>Conclusion Taken together, these data provide a unique insight into epithelial function in this key model insect, and a framework for comparison with other species. They also provide a methodology for function-led datamining of FlyAtlas.org and other multi-tissue expression datasets.</p&gt

Functional correlates of positional and gender-specific renal asymmetry in drosophila

Accordingly, the physical asymmetry of the tubules in the body cavity is directly adaptive. Now that the detailed machinery underlying internal asymmetry is starting to be delineated, our work invites the investigation, not just of tissues in isolation, but in the context of their unique physical locations and milieux

Simulation of multi-deck medium temperature display cabinets with the integration of CFD and cooling coil models

This is the post-print version of the final paper published in Applied Energy. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2010 Elsevier B.V.In this paper, the model for the multi-deck medium temperature display cabinets is developed with the integration of CFD and cooling coil sub-models. The distributed method is used to develop the cooling coil model with the airside inputs from the outputs of the CFD model. Inversely, the airside outputs from the cooling coil model are used to update the boundary conditions of the CFD model. To validate this cabinet model, a multi-deck medium temperature display cabinet refrigerated with a secondary refrigerant cooling coil was selected as a prototype and mounted in an air conditioned chamber. Extensive tests were conducted at constant space air temperature and varied relative humilities. The cabinet model has been validated by comparing with the test results for the parameters of air at different locations of the flow path, and temperatures of refrigerant and food product, etc. The validated model is therefore used to explore and analyse the cabinet performance and control strategies at various operating and design conditions.DEFR

Precipitation and latent heating distributions from satellite passive microwave radiometry. Part I: improved method and uncertainties

A revised Bayesian algorithm for estimating surface rain rate, convective rain proportion, and latent heating profiles from satellite-borne passive microwave radiometer observations over ocean backgrounds is described. The algorithm searches a large database of cloud-radiative model simulations to find cloud profiles that are radiatively consistent with a given set of microwave radiance measurements. The properties of these radiatively consistent profiles are then composited to obtain best estimates of the observed properties. The revised algorithm is supported by an expanded and more physically consistent database of cloud-radiative model simulations. The algorithm also features a better quantification of the convective and nonconvective contributions to total rainfall, a new geographic database, and an improved representation of background radiances in rain-free regions. Bias and random error estimates are derived from applications of the algorithm to synthetic radiance data, based upon a subset of cloud-resolving model simulations, and from the Bayesian formulation itself. Synthetic rain-rate and latent heating estimates exhibit a trend of high (low) bias for low (high) retrieved values. The Bayesian estimates of random error are propagated to represent errors at coarser time and space resolutions, based upon applications of the algorithm to TRMM Microwave Imager (TMI) data. Errors in TMI instantaneous rain-rate estimates at 0.5°-resolution range from approximately 50% at 1 mm h−1 to 20% at 14 mm h−1. Errors in collocated spaceborne radar rain-rate estimates are roughly 50%–80% of the TMI errors at this resolution. The estimated algorithm random error in TMI rain rates at monthly, 2.5° resolution is relatively small (less than 6% at 5 mm day−1) in comparison with the random error resulting from infrequent satellite temporal sampling (8%–35% at the same rain rate). Percentage errors resulting from sampling decrease with increasing rain rate, and sampling errors in latent heating rates follow the same trend. Averaging over 3 months reduces sampling errors in rain rates to 6%–15% at 5 mm day−1, with proportionate reductions in latent heating sampling errors

Formation of an Edge Striped Phase in Fractional Quantum Hall Systems

We have performed an exact diagonalization study of up to N=12 interacting electrons on a disk at filling $\nu={1/3}$ for both Coulomb and $V_1$ short-range interaction for which Laughlin wave function is the exact solution. For Coulomb interaction and $N\geq 10$ we find persistent radial oscillations in electron density, which are not captured by the Laughlin wave function. Our results srongly suggest formation of a chiral edge striped phase in quantum Hall systems. The amplitude of the charge density oscillations decays slowly, perhaps as a square root of the distance from the edge; thus the spectrum of edge excitations is likely to be affected.Comment: 4 pages, 3 Figs. include

Rotational and Vibrational Dynamics of Interstitial Molecular Hydrogen

The calculation of the hindered roton-phonon energy levels of a hydrogen molecule in a confining potential with different symmetries is systematized for the case when the rotational angular momentum $J$ is a good quantum number. One goal of this program is to interpret the energy-resolved neutron time of flight spectrum previously obtained for H$_{2}$C$_{60}$. This spectrum gives direct information on the energy level spectrum of H$_2$ molecules confined to the octahedral interstitial sites of solid C$_{60}$. We treat this problem of coupled translational and orientational degrees of freedom a) by construction of an effective Hamiltonian to describe the splitting of the manifold of states characterized by a given value of $J$ and having a fixed total number of phonon excitations, b) by numerical solutions of the coupled translation-rotation problem on a discrete mesh of points in position space, and c) by a group theoretical symmetry analysis. Results obtained from these three different approaches are mutually consistent. The results of our calculations explain several hitherto uninterpreted aspects of the experimental observations, but show that a truly satisfactory orientational potential for the interaction of an H$_2$ molecule with a surrounding array of C atoms has not yet been developed.Comment: 53 pages, 9 figures, to appear in Phys. Rev B (in press). Phys. Rev. B (in press

A spectroscopic and thermal investigation into the relationship between composition, secondary structure and physical characteristics of electrospun zein nanofibers

Electrospun zein nanofibers have attracted interest as drug delivery systems due to their propensity for controlled drug release, flexible structure and low toxicity. However, comparatively little is known regarding the relationship between production method and fiber characteristics, both in terms of fiber architecture and protein structure. Here we use a range of imaging and spectroscopic techniques to elucidate the effects of solvent composition on zein secondary structure, fiber diameter and fiber integrity, plus we utilize the new technique of transition temperature microscopy to examine the thermal properties of the fibers. Zein nanofibers were prepared using ethanol, acetic acid and water mixes as solvents, alone and with plasticizers (polyethylene glycol, glycerol) and casein. Electrospinning was performed under controlled conditions and the products characterized using scanning electron microscopy (SEM), attenuated total reflection Fourier Transform infrared spectrometry (ATR - FTIR) and transition temperature microscopy (TTM). The choice of solvent, concentration and voltage, alongside the presence of additives (plasticizers and casein) were noted to influence both the diameter of the fibers and the tendency for bead formation. A relationship was noted between protein secondary structure and fiber architecture, with an enhanced β-sheet content, enhanced by the inclusion of casein, being associated with higher beading. In addition, thermal imaging of electrospun zein fiber mats was successfully achieved using TTM via two dimensional mapping of the softening temperatures across the spun samples, in particular demonstrating the plasticizing effects of the polyethylene glycol and glycerol

The thermodynamic evolution of the cosmological event horizon

By manipulating the integral expression for the proper radius $R_e$ of the cosmological event horizon (CEH) in a Friedmann-Robertson-Walker (FRW) universe, we obtain an analytical expression for the change \dd R_e in response to a uniform fluctuation \dd\rho in the average cosmic background density $\rho$. We stipulate that the fluctuation arises within a vanishing interval of proper time, during which the CEH is approximately stationary, and evolves subsequently such that \dd\rho/\rho is constant. The respective variations 2\pi R_e \dd R_e and \dd E_e in the horizon entropy $S_e$ and enclosed energy $E_e$ should be therefore related through the cosmological Clausius relation. In that manner we find that the temperature $T_e$ of the CEH at an arbitrary time in a flat FRW universe is $E_e/S_e$, which recovers asymptotically the usual static de Sitter temperature. Furthermore, it is proven that during radiation-dominance and in late times the CEH conforms to the fully dynamical First Law T_e \drv S_e = P\drv V_e - \drv E_e, where $V_e$ is the enclosed volume and $P$ is the average cosmic pressure.Comment: 6 page

Annual crop rooting depth: what do we really know?

Non-Peer Reviewe