Assessment of water quality in Canaanland, Ota, Southwest Nigeria

In this study, water points in Canaanland, Ota, and nearby Iju River were analyzed for biological and physicochemical properties including heavy metal content. Water quality parameters examined were pH, alkalinity, salinity, conductivity, turbidity, total hardness, total solids (TS), total dissolved solids (TDS), total suspended solids (TSS), dissolved oxygen (Do), biochemical oxygen demand (BOD), iron (Fe), lead (Pb), zinc (Zn) and chromium (Cr). All the water samples were slightly acidic (5.96 – 6.54) except the bottled/ sachet Hebron water and Iju River water. The results were compared against drinking water quality standards laid by World Health Organization (WHO) and Nigerian Standard for Drinking Water (NSDW). The potable water samples were within the standards for consumable water and so are considered safe for human consumption. The surface waters, on the other hand, have high levels of total dissolved solids, conductivity and salinity. The BOD of the effluent water showed that the water was contaminated and the use of the water for domestic purposes by the inhabitants could lead to hazardous side effects

Use Of Informatıon And Communıcatıon Technology (Ict) Devıces For Instructıonal Delıvery In Secondary Schools In Ebonyı State Of Nıgerıa

The study examined teachers perceptions on the use of information and communication technology (ICT) devices for instructional delivery in secondary schools in Ebonyi State, Nigeria. Four research questions guided the study. The population of the study comprised of all the three thousand two hundred and eighty-five (3,285) teacher in the two hundred and twenty-one (221) public secondary schools in Ebonyi State. Simple random sampling technique was used to select (8) teachers each from ninety schools used for the study to give a sample of seven hundred and twenty (720) respondents. The instrument used for data collection was structured questionnaire. Pearson’s Moment Correlation Co-efficient was used to calculate the reliability co-efficient of the pilot tests to get established reliability value of 0.79. The data collected were analysed using mean scores. It was found among other things that ICT devices are not adequately available, most available ICT devices are not in good working condition in schools studied, hence they are not adequately used and above all trained personnel are not also adequately available to operate the functional ones. Government through her appropriate agencies should as a matter of urgency procure and distribute the necessary ICT devices to secondary schools, more trained personnel should be recruited but for the interim the available ones could be retrained through short term holiday programmes, workshops and conferences to ensure adequate use and maintenance of these ICT devices as this will go a long way in improving instructional delivery in Ebonyi State Secondary Schools

Postnatal probiotic supplementation can prevent and optimize treatment of childhood asthma and atopic disorders: a systematic review of randomized controlled trials

Background: Although several randomized controlled trials (RCTs) published over the past 5 years show that prenatal or postnatal probiotics may prevent or optimize the treatment of childhood asthma and atopic disorders, findings from the systematic reviews and meta-analyses of these studies appear inconsistent. More recent RCTs have focused on postnatal probiotics, and linked specific probiotic strains to better disease outcomes. Objective: This systematic review aimed to determine if postnatal probiotics are as effective as prenatal probiotics in preventing or treating childhood asthma and atopic disorders. Methods: We searched the PubMed, Medline, Google Scholar, and EMBASE databases for RCTs published within the past 5 years (from 2017 to 2022). We included only full-text RCTs on human subjects published in or translated into the English language. We retrieved relevant data items with a preconceived data-extraction form and assessed the methodological quality of the selected RCTs using the Cochrane Collaboration's tool for assessing the risk of bias in randomized trials. We qualitatively synthesized the retrieved data to determine any significant differences in study endpoints of the probiotic and placebo groups. Results: A total of 1,320 participants (688 and 632 in the probiotic and placebo groups) from six RCTs were investigated. One RCT showed that early Lactobacillus rhamnosus GG (LGG) led to a reduction in the cumulative incidence rate of asthma. Another study demonstrated that mixed strains of Lactobacillus paracasei and Lactobacillus fermentum could support clinical improvement in children with asthma while one trial reported a significant reduction in the frequency of asthma exacerbations using a mixture of Ligilactobacillus salivarius and Bifidobacterium breve. Three trials showed that a combination of LGG and Bifidobacterium animalis subsp lactis, Lactobacillus rhamnosus alone, and a probiotic mixture of Lactobacillus LOCK strains improved clinical outcomes in children with atopic dermatitis and cow-milk protein allergy. Conclusions: Postnatal strain-specific probiotics (in single or mixed forms) are beneficial in preventing and treating atopic dermatitis and other allergies. Similarly, specific strains are more effective in preventing asthma or improving asthma outcomes. We recommend more interventional studies to establish the most useful probiotic strain in these allergic diseases

Geological and Geotechnical Evaluation of Gully Erosion at Nguzu Edda, Afikpo Sub-Basin, Southeastern Nigeria

A detailed geological field mapping of Nguzu Edda has revealed that gully erosion and landslides have remained active over the years, posing serious threats to human life, agricultural land, infrastructure and socio-economic activities within the area. Consequently, twelve true representative soil samples from different locations within gully sites have been analyzed based on ASTM and British Standards, to evaluate geologic conditions and geotechnical parameters that influence the gullies problems. The results of the laboratory tests revealed that the soil at the gully sites are predominantly sands (57~99.5 % with mean of 69.7%) with low amount of fines (silt; 0.3~ 22% with average value of 14.6% and clay: 0.2 ~ 21% with average value of 13.9%). The liquid limit (LL) ranged from 15 ~ 31.50 % with mean of 23.32% and the plasticity index (PI) ranged from 2.92~14.42% with mean of 8.95%. The moisture content, permeability, bulk density, porosity, organic matter and pH have average values of 25.31%, 6.04×10-4 cm/sec, 1.55 kg/m3, 40.40, 1.26% and 5.12, respectively. The cation exchange capacity (CEC) is low, which could be attributed to low organic matter, pH and non active clay minerals. With regard to the aforementioned characteristics, the soils at gully sites are loose sands with low amount of fines fraction, hence cohesionless, and are easily exposed to agents/factors of gully erosion. Thus, provides insights about the vulnerable causes of gully erosion and landslides problems that are prevalent in the area. This research addresses, to a great extent the effects of local geology, geotechnical properties of the underlying soil and associated human activities on the formation of gully erosion, in-turn results to landslides within in the study area. Engineering-geologic aspects of soil erosion control were also recommended. Keywords: Afikpo Sub-basin, Geologic conditions, Geotechnical analysis, Gully erosion and Erosion control measures

A profile of wound infections in National Hospital Abuja

Background: Wound Infections cause prolonged hospital stay, increased costs and also can result in increased patient morbidity and mortality.The current spread of multi -drug resistant bacteria has further heightened the need for regular bacteriological review of infected wounds and regular antibiotics surveillance studies so as to avoid the unguided empirical treatment of wound infections which is quite common in this environmentAim: To determine the distribution of the isolates from wound specimens submitted to the medical microbiology laboratory of National Hospital Abuja for processing.Method: A review and analysis of 380 woundspecimens results from various wards in the hospital over a period of 10 months (1st Marto Dec 31st 2010) was conducted.Result: A total of 314 isolates were recovered from the 380 wound specimens giving a yield of 83%. 240(76%) yielded single isolates of various pathogens, while 74(24%) were poly-microbial. Gram negative bacilli constituted 66% of all the pathogens with Pseudomonas aeruginosa (19%) and Proteus species (18%) as the most frequent, while gram positive isolates made up 33% with S aureus (27%) as most predominant and most frequently isolated bacteria from all the wound specimens. Two candida species comprised about 1% of the isolates. Frequency of infection was highest in surgical wards (27%), gynaecology ward (14%) and accident and emergency unit (12%). The fluoroquinolones, aminoglycosides, and Beta-lactam antibiotics were the most effective drugs for most of the isolates. Staphylococcus aureus was most sensitive to amikacin (83%) and erythromycin (79%); Pseudomonas aeruginosa to imipenem (96%) and amikacin (83%) and Proteus species to amikacin (100%) and imipenem (78%).Conclusion: S aureus, Pseudomonas aeruginosa and Proteus species were the predominant bacteria from wounds, with surgery and gynaecology wards having the highest prevalence. Resistance to commonly used antibiotics is high. There is need to institute antibiotic stewardship and effective and efficient infection control measures in the hospitalKeywords: Wound infections, National Hospital , Abuj

Compressive shock resulting from gastric distension after arterial switch operation: a case report

Compressive shock is an important cause of reversible cardiovascular compromise. Abdominal causes of compressive shock have been known to be difficult to diagnose. We report our experience in the management of compressive shock resulting from gastric distension. We consider gastric distension to be an unusual cause of compressive shock. Immediate relief of intra-abdominal tension is key in the management

Common Errors in Proposals and Dissertations and How to Avoid them: A Resident’s Guide

Background: The dissertation is now a necessary part of the fellowship examinations of both the West African college of surgeons and physiciansand the national postgraduate medical college of Nigeria. Many resident doctors are confused about how to get on with their proposals and thedissertations. This confusion often leads to frustrations, and in extreme cases to unnecessary delay in attempting the examinations when due. Aim: This study aims to identify the common errors made by resident doctors in the proposal and dissertations and to recommend the solutionsto such problems. Methods: This survey is based on a direct interview with experienced examiners in both colleges. The examiners were asked to list what they observed as the common problems they identified concerning the proposal and dissertation of residents. The answers were collated and categorized according to the frequencies of problems identified. Based on the response of the examiners, a questionnaire was designed and administered to the senior residents who are at various stages of writing their dissertations. Results: Some of the findings include starting the proposal too late, difficulty in choosing a topic, mediocre and tedious literature search, difficulty in finding appropriate supervisors, poor appreciation of basic research design and necessary statistical tests, improper presentation of results and  wrong referencing. Others are editorial mistakes, pagination errors, and the lack of knowledge on proper attitude and skill during the defense.  Conclusion: Starting too late is the most common error made by the resident doctor in the dissertation. Residents should choose a topic within 6  months of passing the membership examination. Keywords: Dissertations, errors, proposals, resident doctor

Moringa oleifera Improves Skeletal Muscle Metabolism and Running Performance in Mice

Background: Recent estimates suggest that 7% of Americans use plant-derived nutritional supplements to treat a variety of complications and/or to improve athletic performance and skeletal muscle health. Unfortunately, these supplements are largely unregulated and understudied. For example, Moringa oleifera (M. oleifera) is a subtropical plant and is routinely used to treat inflammation, diabetes, obesity, cancer and HIV. However, the mechanism of action of M. oleifera has not been fully elucidated, thus the purpose of this study is to evaluate the role of M. oleifera as a novel ergogenic aid to improve exercise performance by driving peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α)-dependent signaling pathways implicated in mitochondrial biogenesis and oxidative metabolism in skeletal muscle tissue. Methods: Adult male C57BL/6 mice were treated with 1.0 g of M. oleifera (N = 20) per day or vehicle control (N = 20) for a total of 5 weeks. Following 3 weeks of supplementation, half of each group (RUN) was given access to running wheels every night for 2 weeks (Remaining half = SED), distances ran were recorded daily. After treatment protocols were complete, the gastrocnemius muscles were excised and assayed for known markers of mitochondrial biogenesis, angiogenesis, endurance capacity, and capillary density using immunohistochemistry and RT-PCR. Results: Our results showed a significant increase in average distance run in the M. oleifera + SED and M. oleifera + RUN groups. This physiological trend was consistent with the molecular profile of key metabolic markers, i.e., there was an increase in levels of PGC-1α, PPARγ, SDHB, SUCLG1, VEGF, PGAM-2, PGK1, and MYLPF in the M. oleifera treated groups compared to vehicle + SED. Moreover, M. oleifera also increased CSA and decreased markers of protein degradation. Conclusions: This data suggests that M. oleifera has the potential to be an ergogenic aid via enhancing energy metabolism in adult skeletal muscle by increasing the expression of key metabolic markers, including those involved in glycolysis, oxidative phosphorylation, mitochondrial biogenesis and angiogenesis

Physical and Mechanical Properties of Pressed Palm Oil Fruit Fiber Reinforced Epoxy Composite for Building Partition Panels

The density, water absorption, and mechanical properties of the pressed palm oil fruit fiber (PPOFF) epoxy composite were investigated. The fibers were matted randomly and laminated with epoxy resin and hardener using hand-lay-up method. The result of the analysis of the developed composite indicated that mass fraction of the PPOFF used in this study was less than the threshold to effect increase in the tensile properties of the resin. However, the properties increased with increase in the fiber content. Also, the density of the composite decreased while the water absorption increased as the fiber content increases. The XRD result indicated that the fibers has high crystallinity index indicating rich cellulose content but the scanning electron microscope (SEM) micrograph revealed weakly bonded fibers to the matrix due to the poor dispersion and wet-ability between the two phases. The developed composite can be useful in building partition panels

PREVALENCE AND RISK FACTORS FOR HEPATITIS C AND HUMAN IMMUNODEFICIENCY VIRUS CO-INFECTION AMONG CHILDREN IN ENUGU, NIGERIA

Background: Hepatitis C virus (HCV) and Human Immunodeficiency virus (HIV), are major public health challenges in the developing world especially sub-Saharan Africa. The aim of this study was to determine the prevalence and risk factors of Hepatitis C virus infection among children infected with HIV. Methods: This was a cross-sectional study conducted at the Paediatric HIV Clinic, UNTH, Enugu between July and December 2009. Antibodies to HCV were analyzed by newer generation rapid chromatographic immunoassay method using the Chromatest one step HCV test kit. The data was analysed using the Statistical Package for Social Sciences (SPSS) version 15 statistical software. The chi squared test was used to test for significant association of categorical variables. A p-value o