Innovación educativa en España: Un estudio descriptivo a partir de los datos contenidos en REDINED

Educative innovation goes beyond changes in methodology and teaching. It suggests an ideological reflection that is always within a particular context. This is the reason for the great difficulty in applying resources or materials into a particular context derived from the educative innovation without a thorough debate. In this paper, we propose a research that combines the active process of the information found in the records of educational innovation within the REDINED Data Base, and to examine it within a quantitative and qualitative framework. Introducing the technical side of the study, we have included a brief description of the used software: CDS/ISIS is a system of document management developed by UNESCO. It permits storage and a recovery of great volumes of information, as well as offering a combination of different types of searches. Hence, we have used the program WinISIS, which is a version for Windows of CDS/ISIS keeping REDINED´s database. WinISIS allows searches in Inverted file and in free text searches based on a reading in accordance with the Master file, combining the terms of search with logical operators (Boolean expressions). These searches permit us to achieve the statistics contained by the percentage of success of the requests, which were formulated from the starting point. La innovación educativa va más allá del cambio metodológico y didáctico ya que implica una reflexión ideológica que nunca tiene lugar fuera de un contexto. Esta es la razón que explica la dificultad de aplicar el recurso o los materiales generados en los procesos innovadores de un contexto a otro sin el necesario debate. En este artículo nos proponemos realizar un estudio descriptivo que combine la explotación de la información contenida en los registros de innovación de la Base de Datos REDINED, tratados cuantitativa y cualitativamente. Para presentar el proceso técnico de la investigación hemos realizado una breve descripción del software utilizado: CDS/ISIS, que es un sistema de gestión documental desarrollado por la UNESCO que permite almacenar y recuperar grandes volúmenes de datos, así como la combinación de distintos tipos de búsquedas para las que hemos utilizado el programa WinISIS, que es una versión para Windows de CDS/ISIS en la que está disponible la base de datos REDINED. WinISIS permite realizar búsquedas a través del archivo invertido o búsquedas en texto libre basadas en la lectura secuencial del archivo Maestro, combinando los términos de búsqueda con operadores booleanos. Estas búsquedas nos facilitan obtener las estadísticas porcentuales de los éxitos de las peticiones formuladas a la base

Atherosclerotic Pre-Conditioning Affects the Paracrine Role of Circulating Angiogenic Cells Ex-Vivo

In atherosclerosis, circulating angiogenic cells (CAC), also known as early endothelial progenitor cells (eEPC), are thought to participate mainly in a paracrine fashion by promoting the recruitment of other cell populations such as late EPC, or endothelial colony-forming cells (ECFC), to the injured areas. There, ECFC replace the damaged endothelium, promoting neovascularization. However, despite their regenerative role, the number and function of EPC are severely affected under pathological conditions, being essential to further understand how these cells react to such environments in order to implement their use in regenerative cell therapies. Herein, we evaluated the effect of direct incubation ex vivo of healthy CAC with the secretome of atherosclerotic arteries. By using a quantitative proteomics approach, 194 altered proteins were identified in the secretome of pre-conditioned CAC, many of them related to inhibition of angiogenesis (e.g., endostatin, thrombospondin-1, fibulins) and cell migration. Functional assays corroborated that healthy CAC released factors enhanced ECFC angiogenesis, but, after atherosclerotic pre-conditioning, the secretome of pre-stimulated CAC negatively affected ECFC migration, as well as their ability to form tubules on a basement membrane matrix assay. Overall, we have shown here, for the first time, the effect of atherosclerotic factors over the paracrine role of CAC ex vivo. The increased release of angiogenic inhibitors by CAC in response to atherosclerotic factors induced an angiogenic switch, by blocking ECFC ability to form tubules in response to pre-conditioned CAC. Thus, we confirmed here that the angiogenic role of CAC is highly affected by the atherosclerotic environment

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

¿Qué queda de mí?

Este libro es una reclamación a quienes hemos sido, somos o seremos docentes. A quienes no hemos respetado a las personas que se han puesto junto a nosotros y nosotras, confiando su bien más preciado: la libertad. Estas páginas denuncian cada vez que convertimos una visión en la visión, una emoción en la emoción, un saber en el saber, un comportamiento en el comportamiento. Es un grito contra la imposición, la normalización, la neutralización y la universalización de una perspectiva particular. Una pugna contra cada proceso que no se ha conectado con las vidas de los aprendices. Un texto colaborativo realizado por alumnado de Educación y Cambio Social en el Grado en Educación Infantil de la Universidad de Málaga y coordinado por Ignacio Calderón Almendros

Innovación educativa en España: Un estudio descriptivo a partir de los datos contenidos en REDINED

La innovación educativa va más allá del cambio metodológico y didáctico ya que implica una reflexión ideológica que nunca tiene lugar fuera de un contexto. Esta es la razón que explica la dificultad de aplicar el recurso o los materiales generados en los procesos innovadores de un contexto a otro sin el necesario debate. En este artículo nos proponemos realizar un estudio descriptivo que combine la explotación de la información contenida en los registros de innovación de la Base de Datos REDINED, tratados cuantitativa y cualitativamente. Para presentar el proceso técnico de la investigación hemos realizado una breve descripción del software utilizado: CDS /ISIS, que es un sistema de gestión documental desarrollado por la UNESCO que permite almacenar y recuperar grandes volúmenes de datos, así como la combinación de distintos tipos de búsquedas para las que hemos utilizado el programa WinISIS, que es una versión para Windows de CDS /ISIS en la que está disponible la base de datos REDINED. WinISIS permite realizar búsquedas a través del archivo invertido o búsquedas en texto libre basadas en la lectura secuencial del archivo Maestro, combinando los términos de búsqueda con operadores booleanos. Estas búsquedas nos facilitan obtener las estadísicas porcentuales de los éxitos de las peticiones formuladas a la base

Down syndrome as risk factor for respiratory syncytial virus hospitalization : A prospective multicenter epidemiological study

Respiratory syncytial virus (RSV) infection in childhood, particularly in premature infants, is associated with significant morbidity and mortality. To compare the hospitalization rates due to RSV infection and severity of disease between infants with and without Down syndrome (DS) born at term and without other associated risk factors for severe RSV infection. In a prospective multicentre epidemiological study, 93 infants were included in the DS cohort and 68 matched by sex and data of birth (±1 week) and were followed up to 1 year of age and during a complete RSV season. The hospitalization rate for all acute respiratory infection was significantly higher in the DS cohort than in the non-DS cohort (44.1% vs 7.7%, P<.0001). Hospitalizations due to RSV were significantly more frequent in the DH cohort than in the non-DS cohort (9.7% vs 1.5%, P=.03). RSV prophylaxis was recorded in 33 (35.5%) infants with DS. The rate of hospitalization according to presence or absence of RSV immunoprophylaxis was 3.0% vs 15%, respectively. Infants with DS showed a higher rate of hospitalization due to acute lower respiratory tract infection and RSV infection compared to non-DS infants. Including DS infants in recommendations for immunoprophylaxis of RSV disease should be considered

Role of age and comorbidities in mortality of patients with infective endocarditis.

The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups: A total of 3120 patients with IE (1327  There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in th

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective