Scanning Electron Microscope Study of Wohlfahrtia magnifica (Schiner, 1862) (Diptera: Sarcophagidae) I. Structures with Parasitic and Possible Taxonomic Meaning

The larval development of Wohlfahrtia magnifica (the most important dipteran causing sheep myiasis in the Palearctic region) has been studied by means of scanning electron microscopy. The ultrastructure of mouth-hooks, oral ridges, labial lobes, body spines and anterior and posterior peritremes is described for the first time. Their possible adaptations to a parasitic lifeway are also discussed. Thus, the use of new structures in the Sarcophagidae taxonomy is proposed from the point of view of their ultrastructure and adaptative morphology

Lifetime psychotic symptoms, subthreshold depression and cognitive impairment as barriers to functional recovery in patients with bipolar disorder

Background: bipolar disorder (BD) is a chronic disease that often leads to functional impairment. The objective of this study is to elucidate which variables are associated with better functional outcomes in a sample of euthymic patients with BD. (2) Methods: patients were recruited at the Hospital Clinic of Barcelona and they underwent a clinical interview, a functional assessment, and a comprehensive neuropsychological evaluation. After that, patients were divided into two groups according to the Functioning Assessment Short Test total score: functionally remitted vs. functionally impaired. Following this, a multivariate logistic regression was run in order to identify clinical, demographic and cognitive factors associated with functional remission. (3) Results: a total of 420 euthymic patients with BD were assessed for this study, distributed as follows: functionally remitted (n = 221) and functionally impaired (n = 199). Finally, the multivariate logistic regression revealed that only five variables significantly contributed to the model, including: lifetime history of psychotic symptoms (the variable that contributed the most to the model), followed by the Hamilton Depression total score, and cognitive performance (executive functions and verbal memory). (4) Conclusions: treatments to ensure a good functional outcome in BD should specially prevent psychosis, target subthreshold depressive symptoms and enhance cognition, more specifically executive functions and verbal memory

Association between an oxidative balance score and mortality: a prospective analysis in the SUN cohort

We aimed to prospectively investigate the association of an overall oxidative balance score (OBS) with all-cause death and cause-specifc mortality among participants in the Seguimiento Universidad de Navarra (SUN) Study, a Mediterranean cohort of Spanish graduates. Methods Using baseline information on 12 a priori selected dietary and non-dietary lifestyle pro- and antioxidants exposures—vitamins C and E, β-carotenes, selenium, zinc, heme iron, polyphenols, total antioxidant capacity, body mass index, alcohol, smoking, and physical activity—we constructed an equally weighted OBS categorized into quartiles, with higher scores representing greater antioxidant balance. Cox proportional hazards models were ftted to evaluate the association between the OBS and mortality. Results A total of 18,561 participants (mean [SD] age, 38.5 [12.4] years; 40.8% males) were included in the analysis. During a median follow-up of 12.2 years (interquartile range 8.3–14.9), 421 deaths were identifed, including 80 deaths from cardiovascular disease (CVD), 215 from cancer, and 126 from other causes. After adjustment for potential confounders, the hazard ratios and 95% confdence interval (CIs) between the highest quartile (predominance of antioxidants) vs. the lowest quartile (reference category) were 0.35 (95% CI 0.22–0.54, P-trend<0.001) for all-cause mortality, 0.18 (95% CI 0.06–0.51, P-trend=0.001) for CVD mortality, 0.35 (95% CI 0.19–0.65, P-trend=0.002) for cancer mortality, and 0.45 (95% CI 0.20–1.02, P-trend=0.054) for other-cause mortality. Conclusion Our fndings suggest a strong inverse association between the OBS and all-cause, CVD, and cancer mortality. Individuals exposed to both antioxidant dietary and lifestyle factors may potentially experience the lowest mortality riskOpen Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. The SUN Project has received funding from the Spanish Government-Instituto de Salud Carlos III, and the European Regional Development Fund (FEDER) (RD 06/0045, CIBER-OBN, Grants PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, PI17/01795, and G03/140), the Navarra Regional Government (27/2011, 45/2011, 122/2014), the Government Delegation for the National Drug Plan (2020/ 021) and the University of Navarra. Maria Soledad Hershey receives ERC traininggrant support (T42 OH008416

Estudio del desarrollo corporal de bovinos cruzados Wagyu-Brahman en el trópico húmedo, Panamá: Study of body development of Wagyu-Brahman crossbred cattle in the humid tropics, Panama

El objetivo principal fue estudiar el desarrollo corporal de bovinos cruzados Wagyu-Brahman bajo condiciones del trópico húmedo. Los datos provienen de la EEG-CMO-IDIAP (2008-2014). Las variables dependientes fueron: peso al nacimiento (PN), peso vivo (PVKG), cambio de peso vivo (CPV), tasa relativa de crecimiento (TRC), largo corporal (LC), altura a la cadera (AC) y perímetro torácico (PT). Los grupos raciales del padre (GRP) fueron: BRH y WG. Los grupos raciales de la madre (GRM) fueron: BRH, CRUCE, WG50 y WGF1. Los grupos raciales de la progenie (GRANI) fueron; WG25, WG50, WG75 y WGF1. Los datos se analizaron mediante un modelo lineal mixto donde año (YR) y época dentro del año [EP(YR)] fueron efectos aleatorios. El GRP y GRM(GRP) fueron efectos fijos. Además, PVKG, LC, AC y PT de cada GRANI fueron regresados con un modelo no lineal de Brody con la edad. Progenies de BRH tuvieron mayor PN (7,6 %), CPV (20,4 %) y TRC (10,8 %). El GRP como WG, y GRM como WGF1, BRH y CRUCE tuvieron mayor PN (31,5 kg), CPV (0,535 kg/d) y TRC (0,42 %), respectivamente. El modelo de Brody ajustó bien (P&lt;0,01) a los datos de cada GRANI. Se concluye que las variables del desarrollo corporal de los animales fueron afectadas por GRP y GRM(GRP) y que los efectos aleatorios de YR y EP(YR) permitieron reducir sesgos. El modelo no lineal de Brody ajustó bien a los datos de las variables de desarrollo corporal.El objetivo principal fue estudiar el desarrollo corporal de bovinos cruzados Wagyu-Brahman bajo condiciones del trópico húmedo. Los datos provienen de la EEG-CMO-IDIAP (2008-2014). Las variables dependientes fueron: peso al nacimiento (PN), peso vivo (PVKG), cambio de peso vivo (CPV), tasa relativa de crecimiento (TRC), largo corporal (LC), altura a la cadera (AC) y perímetro torácico (PT). Los grupos raciales del padre (GRP) fueron: BRH y WG. Los grupos raciales de la madre (GRM) fueron: BRH, CRUCE, WG50 y WGF1. Los grupos raciales de la progenie (GRANI) fueron; WG25, WG50, WG75 y WGF1. Los datos se analizaron mediante un modelo lineal mixto donde año (YR) y época dentro del año [EP(YR)] fueron efectos aleatorios. El GRP y GRM(GRP) fueron efectos fijos. Además, PVKG, LC, AC y PT de cada GRANI fueron regresados con un modelo no lineal de Brody con la edad. Progenies de BRH tuvieron mayor PN (7,6 %), CPV (20,4 %) y TRC (10,8 %). El GRP como WG, y GRM como WGF1, BRH y CRUCE tuvieron mayor PN (31,5 kg), CPV (0,535 kg/d) y TRC (0,42 %), respectivamente. El modelo de Brody ajustó bien (P<0,01) a los datos de cada GRANI. Se concluye que las variables del desarrollo corporal de los animales fueron afectadas por GRP y GRM(GRP) y que los efectos aleatorios de YR y EP(YR) permitieron reducir sesgos. El modelo no lineal de Brody ajustó bien a los datos de las variables de desarrollo corporal.The main objective was to study the body development of crossbred Wagyu-Brahman bovines under humid tropical conditions. Data came from EEG-CMO-IDIAP (2008-2024). Dependent variables were birth weight (PN), live weight (PVKG), live weight change (CPV), relative growth rate (TRC), body length (LC), hip height (AC), and thorax perimeter (PT). Sire breed group (GRP) were BRH and WG. Dam breed group (GRM) were BRH, CRUCE, WG50, and WGF1. Progeny breed group (GRANI) were WG25, WG50, WG75, and WGF1. Data were analyzed by a mixed linear model where year (YR) and season within year [EP(YR)] were randoms and GRP and GRM(GRP) were fixed. Besides, PVKG, LC, AC, and PT for each GRANI were regressed with a Brody non-linear model on age. Brahman progenies had higher PN (7,6 %), CPV (20,4 %) and TRC (10,8 %). The GRP like WG, and GRM like WGF1, BRH, and CRUCE had higher PN (31,5 kg), CPV (0,535 kg/d), and TRC (0,42 %), respectively. Brody non-linear model adjusted well (P<0,01) to data of each GRANI. It was concluded that body development variables of the animals were affected by GRP and GRM(GRP) and random effects of YR and EP(YR) allowed to reduce bias. The Brody non-linear model adjusted well to the body development data

Family factors associated to eating disorders: A review / Factores familiares asociados a los trastornos alimentarios: Una revisión

AbstractFrom a multifactorial perspective this study present a review about the family factors associated to eating disorders, considering theoretical and empirical contributions in national and international journals articles . The find of the research about the Eating Disordersand Family, indicate that the principal topics investigated are: family functioning, daughters and fathers relationships, stressful experiences, family psychopathology, attitudes and behaviors about weigh, eating and body image in the affected families. We conclude recognizing the heterogeneity of the families with Eating Disorders and the complex combination of family factors associated to eating psychopathology. More research is suggested about: family functioning in EDNOS patients, the father´s role, protective factors, coping stress, body image and family food.Key words: Eating disorders, family, functioning, psychopathology. Resumen Desde una perspectiva multifactorial el presente trabajo es una revisión sobre los factores familiares asociados a los TCA, considerando las aportaciones teóricas y empíricas propuestas en artículos nacionales e internacionales. Los resultados de la búsqueda sobre TCA y familia, indican que los principales tópicos investigados son: funcionamiento familiar, relaciones hija-padres, experiencias estresantes, psicopatología familiar, actitudes y conductas hacia el peso, alimentación e imagen corporal en las familias afectadas. Se concluye reconociendo la heterogeneidad de las familias con TCA y la compleja combinación de factores familiares asociados a la psicopatología alimentaria. Se sugiere mayor investigación sobre: funcionamiento familiar de las personas con TCANE, el papel del padre, factores de protección, afrontamiento al estrés, imagen corporal y alimentación familiar. Palabras clave: Trastornos alimentario, familia, funcionamiento, psicopatología.

A new method to quantify and compare the multiple components of fitness-A study case with kelp niche partition by divergent microstage adaptations to Temperature

Point 1 Management of crops, commercialized or protected species, plagues or life-cycle evolution are subjects requiring comparisons among different demographic strategies. The simpler methods fail in relating changes in vital rates with changes in population viability whereas more complex methods lack accuracy by neglecting interactions among vital rates. Point 2 The difference between the fitness (evaluated by the population growth rate.) of two alternative demographies is decomposed into the contributions of the differences between the pair-wised vital rates and their interactions. This is achieved through a full Taylor expansion (i.e. remainder = 0) of the demographic model. The significance of each term is determined by permutation tests under the null hypothesis that all demographies come from the same pool. Point 3 An example is given with periodic demographic matrices of the microscopic haploid phase of two kelp cryptic species observed to partition their niche occupation along the Chilean coast. The method provided clear and synthetic results showing conditional differentiation of reproduction is an important driver for their differences in fitness along the latitudinal temperature gradient. But it also demonstrated that interactions among vital rates cannot be neglected as they compose a significant part of the differences between demographies. Point 4 This method allows researchers to access the effects of multiple effective changes in a life-cycle from only two experiments. Evolutionists can determine with confidence the effective causes for changes in fitness whereas population managers can determine best strategies from simpler experimental designs.CONICYT-FRENCH EMBASSADY Ph.D. gran

Identification and Quantification of Urinary Microbial Phenolic Metabolites by HPLC-ESI-LTQ-Orbitrap-HRMS and Their Relationship with Dietary Polyphenols in Adolescents

This study aimed to develop and validate a liquid chromatography/electrospray ionization-linear ion trap quadrupole-Orbitrap-high-resolution mass spectrometry (HPLC/ESI-LTQ-Orbitrap-HRMS) method to identify and quantify urinary microbial phenolic metabolites (MPM), as well as to explore the relationship between MPM and dietary (poly)phenols in Spanish adolescents. A total of 601 spot urine samples of adolescents aged 12.02 ± 0.41 years were analyzed. The quantitative method was validated for linearity, limit of detection, limit of quantification, recovery, intra-and inter-day accuracy and precision, as well as postpreparative stability according to the criteria established by the Association of Official Agricultural Chemists International. A total of 17 aglycones and 37 phase II MPM were identified and quantified in 601 spot urine samples. Phenolic acids were the most abundant urinary MPM, whereas stilbenes, hydroxytyrosol, and enterodiol were the least abundant. Urinary hydroxycoumarin acids (urolithins) were positively correlated with flavonoid and total (poly)phenol intake. An HPLC-ESI-LTQ-Orbitrap-HRMS method was developed and fully validated to quantify MPM. The new method was performed accurately and is suitable for MPM quantification in large epidemiological studies. Urinary lignans and urolithins are proposed as potential biomarkers of grain and nut intake in an adolescent population

Problems of code of products that affect the inventory management: cuban companies case study

Numerous code systems and classification of products and services exist globally, being tendency the standardization of them in the supply chains to achieve higher integration. The correct use of these systems is considered essential in the effectiveness in the inventory management, given its direct relationship with the registration of the primary information and tracing of the products. However, the scientific literature and the academic programs concentrate mostly on the Auto-ID technologies more than in the code structure and the consequences of an incorrect use of the code. The present article reflects the main deficiencies possible to detect in the systems of code of products, using a sample of companies in Cuba. The consequences of these deficiencies are discussed and it is also included a proposal of organization of the code for the Cuban companies

Metabolic syndrome, adiposity, diet, and emotional eating are associated with oxidative stress in adolescents

Background: Metabolic syndrome (MS), a condition related to adiposity and oxidative stress, can develop in adolescence, a critical stage in life that impacts health in adulthood. However, there is scarce scientific research about the relationship between lifestyle factors, emotion management, and oxidative stress in this phase of life.Aim: To analyze whether nutritional parameters, lifestyle factors, emotion management, and MS in adolescents are associated with oxidative stress measured by the biomarker 8-isoprostane.Methods: A cross-sectional study was carried out in 132 adolescents (48.5% girls, aged 12 ± 0.48 years) and data were collected on nutritional parameters (anthropometric measurements, biochemical analyzes, and blood pressure), lifestyle factors (physical activity, sleep, and diet), and emotion management (self-esteem, emotional eating, and mood). 8-isoprostane was analyzed in spot urine samples. The study population was categorized in three groups (healthy, at-risk, and with MS) using the International Diabetes Federation definition of MS in adolescents. To capture more complex interactions, a multiple linear regression was used to analyze the association between 8-isoprostane and the aforementioned variables.Results: Urinary 8-isoprostane levels were significantly higher in the MS group compared to the healthy group (1,280 ± 543 pg./mg vs. 950 ± 416 pg./mg respectively). In addition, univariable analysis revealed positive significant associations between 8-isoprostane and body mass index, waist circumference, waist-to-height ratio, body fat percentage, blood lipid profile and glucose, emotional eating, and refined cereal intake. Conversely, a negative significant association was found between 8-isoprostane and sleep duration and fish intake. The multiple linear regression analysis revealed associations between 8-isoprostane and LDL-c (β = 0.173 value of p = 0.049), emotional eating (low β = 0.443, value of p = 0.036; high β = 0.152, value of p = 0.470), refined cereal intake (β =0.191, value of p = 0.024), and fish intake (β = -0.187, value of p = 0.050).Conclusion: The MS group, LDL-c, emotional eating, and high refined cereals and low fish intakes were associated with higher levels of oxidative stress in an adolescent population.</p