227 research outputs found
Two qubits of a W state violate Bell's inequality beyond Cirel'son's bound
It is shown that the correlations between two qubits selected from a trio
prepared in a W state violate the Clauser-Horne-Shimony-Holt inequality more
than the correlations between two qubits in any quantum state. Such a violation
beyond Cirel'son's bound is smaller than the one achieved by two qubits
selected from a trio in a Greenberger-Horne-Zeilinger state [A. Cabello, Phys.
Rev. Lett. 88, 060403 (2002)]. However, it has the advantage that all local
observers can know from their own measurements whether their qubits belongs or
not to the selected pair.Comment: REVTeX4, 5 page
About entanglement properties of kaons and tests of hidden variables models
In this letter we discuss entanglement properties of neutral kaons systems
and their use for testing local realism. In particular we show that, as
previous proposals, also a scheme recently suggested for performing a test of
hidden variable theories against standard quantum mechanics cannot be
conclusive
Quantum entanglement with acousto-optic modulators: 2-photon beatings and Bell experiments with moving beamsplitters
We present an experiment testing quantum correlations with frequency shifted
photons. We test Bell inequality with 2-photon interferometry where we replace
the beamsplitters by acousto-optic modulators, which are equivalent to moving
beamsplitters. We measure the 2-photon beatings induced by the frequency
shifts, and we propose a cryptographic scheme in relation. Finally, setting the
experiment in a relativistic configuration, we demonstrate that the quantum
correlations are not only independent of the distance but also of the time
ordering between the two single-photon measurements.Comment: 14 pages, 16 figure
New York: the animated city
The urban landscape of New York City is one that is familiar to many, but, through the medium of animation, this familiarity has been consistently challenged. Often metamorphic, and always meticulously constructed, animated imagery encourages reflective thinking. Focusing on the themes of construction, destruction, and interactivity, this article seeks to cast critical light upon the animated double life that New York City has lived through the following moving image texts: Disney’s Fantasia 2000 (1999), Patrick Jean’s computer-generated short Pixels (2009), and Rockstar Games’ open-world blockbuster Grand Theft Auto IV (2008)
Robust generation of entanglement between two cavities mediated by short interactions with an atom
Published versio
A Framework for Organizational Compliance Management Tactics
Abstract. Organizational compliance with laws, industrial standards, procedures and enterprise architectures has become a highly relevant topic for both practitio-ners and academics. However, both the fundamental insights into compliance as a concept and the tactics for bringing an organization into a compliant state have been described in a fragmented manner. Using literature from various disciplines, this paper presents two contributions. First, it describes the fundamental concepts regarding compliance. Second, it presents a framework in which the various tactics for achieving organizational compliance can be positioned
Nonlinear interactions in the thalamocortical loop in essential tremor: A model-based frequency domain analysis.
There is increasing evidence to suggest that essential tremor has a central origin. Different structures appear to be part of the central tremorogenic network, including the motor cortex, the thalamus and the cerebellum. Some studies using electroencephalogram (EEG) and magnetoencephalography (MEG) show linear association in the tremor frequency between the motor cortex and the contralateral tremor electromyography (EMG). Additionally, high thalamomuscular coherence is found with the use of thalamic local field potential (LFP) recordings and tremulous EMG in patients undergoing surgery for deep brain stimulation (DBS). Despite a well-established reciprocal anatomical connection between the thalamus and cortex, the functional association between the two structures during "tremor-on" periods remains elusive. Thalamic (Vim) LFPs, ipsilateral scalp EEG from the sensorimotor cortex and contralateral tremor arm EMG recordings were obtained from two patients with essential tremor who had undergone successful surgery for DBS. Coherence analysis shows a strong linear association between thalamic LFPs and contralateral tremor EMG, but the relationship between the EEG and the thalamus is much less clear. These measurements were then analyzed by constructing a novel parametric nonlinear autoregressive with exogenous input (NARX) model. This new approach uncovered two distinct and not overlapping frequency "channels" of communication between Vim thalamus and the ipsilateral motor cortex, defining robustly "tremor-on" versus "tremor-off" states. The associated estimated nonlinear time lags also showed non-overlapping values between the two states, with longer corticothalamic lags (exceeding 50ms) in the tremor active state, suggesting involvement of an indirect multisynaptic loop. The results reveal the importance of the nonlinear interactions between cortical and subcortical areas in the central motor network of essential tremor. This work is important because it demonstrates for the first time that in essential tremor the functional interrelationships between the cortex and thalamus should not be sought exclusively within individual frequencies but more importantly between cross-frequency nonlinear interactions. Should our results be successfully reproduced on a bigger cohort of patients with essential tremor, our approach could be used to create an on-demand closed-loop DBS device, able to automatically activate when the tremor is on
Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma
Although the over-expression of angiogenic factors is reported in diffuse large B-cell lymphoma (DLBCL), the poor response to anti-VEGF drugs observed in clinical trials suggests that angiogenesis in these tumours might be driven by VEGF-independent pathways. We show that sphingosine kinase-1 (SPHK1), which generates the potent bioactive sphingolipid sphingosine-1-phosphate (S1P), is over-expressed in DLBCL. A meta-analysis of over 2000 cases revealed that genes correlated with SPHK1 mRNA expression in DLBCL were significantly enriched for tumour angiogenesis meta-signature genes; an effect evident in both major cell of origin (COO) and stromal subtypes. Moreover, we found that S1P induces angiogenic signalling and a gene expression programme that is present within the tumour vasculature of SPHK1-expressing DLBCL. Importantly, S1PR1 functional antagonists, including Siponimod, and the S1P neutralising antibody, Sphingomab, inhibited S1P signalling in DLBCL cells in vitro. Furthermore, Siponimod, also reduced angiogenesis and tumour growth in an S1P-producing mouse model of angiogenic DLBCL. Our data define a potential role for S1P signalling in driving an angiogenic gene expression programme in the tumour vasculature of DLBCL and suggest novel opportunities to target S1P-mediated angiogenesis in patients with DLBCL
Powder Compaction: Compression Properties of Cellulose Ethers
Effective development of matrix tablets requires a comprehensive understanding of different raw material attributes and their impact on process parameters. Cellulose ethers (CE) are the most commonly used pharmaceutical excipients in the fabrication of hydrophilic matrices. The innate good compression and binding properties of CE enable matrices to be prepared using economical direct compression (DC) techniques. However, DC is sensitive to raw material attributes, thus, impacting the compaction process. This article critically reviews prior knowledge on the mechanism of powder compaction and the compression properties of cellulose ethers, giving timely insight into new developments in this field
Absorption and diffusion of hydrogen in palladium-silver alloys by density functional theory
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