773 research outputs found
UV Imaging Polarimetry of the peculiar Seyfert 2 galaxy Mrk 477
We present the results of UV imaging polarimetry of the Seyfert 2 galaxy Mrk
477 taken by the Faint Object Camera onboard the Hubble Space Telescope (HST).
From a previous HST UV image (lambda ~ 2180A), Mrk 477 has been known to have
a pointlike bright UV hotspot in the central region, peculiar among nearby
Seyfert 2 galaxies. There are also claims of UV/optical variability, unusual
for a Seyfert 2 galaxy. Our data show that there is an off-nuclear scattering
region ~ 0."6 (~ 500 pc) NE from the hotspot. The data, after the subtraction
of the instrumental effect due to this bright hotspot region, might indicate
that the scattered light is also detected in the central 0."2 radius region and
is extended to a very wide angle. The hotspot location is consistent with the
symmetry center of the PA pattern, which represents the location of the hidden
nucleus, but our data do not provide a strong upper limit to the distance
between the symmetry center and the hotspot. We have obtained high spatial
resolution color map of the continuum which shows that the nuclear spiral arm
of 0."4 scale (~ 300pc) is significantly bluer than the off-nuclear mirror and
the hotspot region. The nature of the hotspot is briefly discussed.Comment: To appear in Ap
UV Imaging Polarimetry of the Seyfert 2 Galaxy Mrk 3
We present UV imaging polarimetry data of the Seyfert 2 galaxy Mrk 3 taken by
the Hubble Space Telescope. The polarized flux is found to be extended to ~1
kpc from the nucleus, and the position angles of polarization are
centrosymmetric, confirming that the polarization is caused by scattering. We
determine the location of the hidden nucleus as the center of this
centrosymmetric pattern. From the polarization images taken in two broad bands,
we have obtained the color distribution of the polarized flux. Some regions
have blue polarized flux, consistent with optically-thin dust scattering, but
some bright knots have a color similar to that of Seyfert 1 nucleus. Also, the
recent Chandra X-ray observation suggests that the ratio of scattered UV flux
to scattered X-ray flux is rather similar to the intrinsic UV/X-ray ratio in a
Seyfert 1 nucleus, if the observed extended X-ray continuum is scattered light.
While the scattered X-ray would be essentially from electron scattering, the UV
slope and UV/X-ray ratio both being similar to Seyfert 1's would lead to two
possibilities as to the nature of the UV scatterers. One is that the UV may
also be scattered by electrons, in which case the scattering gas is somehow
dust-free. The other is that the UV is scattered by dust grains, but the
wavelength-independent UV scattering with low efficiency indicated by the UV
slope and UV/X-ray ratio would suggest that the grains reside in UV-opaque
clouds, or the dust might be mainly composed of large grains and lacks
small-grain population.Comment: 15 pages, 8 figures (plus 2 color versions of grayscale figures), To
appear in ApJ; minor corrections for the proofs of the manuscrip
Avoiding abelian squares in partial words
AbstractErdős raised the question whether there exist infinite abelian square-free words over a given alphabet, that is, words in which no two adjacent subwords are permutations of each other. It can easily be checked that no such word exists over a three-letter alphabet. However, infinite abelian square-free words have been constructed over alphabets of sizes as small as four. In this paper, we investigate the problem of avoiding abelian squares in partial words, or sequences that may contain some holes. In particular, we give lower and upper bounds for the number of letters needed to construct infinite abelian square-free partial words with finitely or infinitely many holes. Several of our constructions are based on iterating morphisms. In the case of one hole, we prove that the minimal alphabet size is four, while in the case of more than one hole, we prove that it is five. We also investigate the number of partial words of length n with a fixed number of holes over a five-letter alphabet that avoid abelian squares and show that this number grows exponentially with n
Below the Lyman Edge: UV Polarimetry of Quasars
The Lyman edge at 912 \AA is an important diagnostic region for studying
quasi-stellar objects (QSOs). In particular, it reveals a great deal about the
physical conditions within the atmospheres of accretion disks, a ubiquitous
component of QSO theories. A robust prediction of accretion disk models is a
significant polarization due to electron scattering just longward (in
wavelength) of the Lyman edge because of the wavelength dependence of the
Hydrogen absorption opacity. Observations of the Lyman edge regions of QSOs
have shown scant evidence for the predicted features-few QSOs show the broad,
partial Lyman edges expected to be common according to most theories, and none
show the high polarizations expected longward of the Lyman edge. Still,
polarization spectra of a small number of QSOs have shown a rising polarization
(up to 20%) at wavelengths shortward of the Lyman edge. We have now doubled our
sample of intermediate-redshift QSOs observed with the HST/FOS
spectropolarimeter to determine the amount of polarization on both sides of the
Lyman limit. For this new sample of six objects, polarizations are low and
mostly consistent with zero below the Lyman edge.
Another important result of the new data is that it strengthens the
conclusion that quasars are generally not polarized significantly just longward
of the Lyman edge at $\sim 1000 \AA. There is no significant statistical
wavelength dependence to the polarization longward of the Lyman edge indicating
that simple plane-parallel atmospheres with scattering-dominated opacity are
not significant sources of UV flux in quasars.Comment: Accepted to Ap.J., 30 pages, 8 figure
Triggered Star Formation in a Massive Galaxy at z=3.8: 4C41.17
Spectropolarimetric observations obtained with the W. M. Keck Telescope of
the z=3.8 radio galaxy 4C41.17 show that the UV continuum emission from this
galaxy, which is aligned with the radio axis, is unpolarized (P[2sigma] <
2.4%). This implies that scattered AGN light, which is generally the dominant
contributor to the rest-frame UV emission in z~1 radio galaxies, is unlikely to
be a major component of the UV flux from 4C41.17. The spectrum shows absorption
lines that are similar to those detected in the spectra of the recently
discovered population of star forming galaxies at z~2-3. A galaxian outflow may
contribute partially to the low ionization absorption lines; however, the high
velocity wings of the high ionization lines are unlikely to be dominated by a
galaxian wind since the implied outflow mass is very large. The detection of
stellar absorption lines, the shape of the SiIV profile, the unpolarized
continuum, the inability of any AGN-related processes to account for the UV
flux, and the similarity of the UV continuum spectra of 4C41.17 and the nearby
starburst region NGC 1741B1 suggest that the UV light in 4C41.17 is dominated
by young stars. If so, the implied star-formation rate is roughly
140-1100Msun/yr. We discuss the possibility that star formation in 4C41.17 was
triggered by the radio source. Our data are consistent with the hypothesis that
4C41.17 is undergoing its major epoch of star formation at z~4, and that by z~1
it will have evolved to have spectral and morphological properties similar to
those observed in known z~1 powerful radio galaxies.Comment: 28 pages (Latex text + figures); Accepted for publication in The
Astrophysical Journal (Dec 1, 1997 issue
Increased dolutegravir peak concentrations in people living with HIV aged 60 and over and analysis of sleep quality and cognition
Background
Demographic data show an increasingly aging HIV population worldwide. Recent concerns over dolutegravir-related neuropsychiatric toxicity have emerged, particularly amongst older HIV patients. We describe the pharmacokinetics (PK) of dolutegravir (DTG) 50mg once daily in people living with HIV (PLWH) aged 60 and older. Additionally, to address the call for prospective neuropsychiatric toxicodynamic data, we evaluate changes in sleep quality and cognitive function after switching to abacavir (ABC)/lamivudine (3TC)/DTG, over 6 months in this population.
Methods
PLWH aged≥60years with HIV-RNA<50copies/mL on any non-DTG based antiretroviral combination were switched to ABC/3TC/DTG. On day 28, 24-hour PK sampling was undertaken. Steady-state PK parameters were compared to a published historical control population aged≤50years. Six validated sleep questionnaires and neurocognitive (Cogstate®) testing were administered pre-switch and over 180 days (NCT02509195).
Results
Forty-three participants were enrolled; 40 completed the PK phase. Overall, five discontinued (two due adverse events, both sleep related, 4.6%). DTG maximum concentration (Cmax) was significantly higher in patients≥60 versus controls (GM 4246ng/mL versus 3402ng/mL, p=0.005). In those who completed day 180 (n=38), sleep impairment was higher at day 28 (PSQI median global score 5.0 versus 6.0 p=0.02) but not at day 90 or 180. Insomnia, daytime function, fatigue test scores did not change statistically over time.
Conclusion
DTG Cmax was significantly higher in older PLWH. Our data provides clinicians with key information on the safety of prescribing DTG in older PLWH
Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses
Introduction: The rising global burden of metabolic disease impacts the control of endemic tuberculosis (TB) in many regions, as persons with diabetes mellitus (DM) are up to three times more likely to develop active TB than those without DM. Active TB can also promote glucose intolerance during both acute infection and over a longer term, potentially driven by aspects of the immune response. Identifying patients likely to have persistent hyperglycemia following TB treatment would enable closer monitoring and care, and an improved understanding of underlying immunometabolic dysregulation.
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Methods: We measured the relationship of plasma cytokine levels, T cell phenotypes and functional responses with the change in hemoglobin A1c (HbA1c) before and after treatment of pulmonary TB in a prospective observational cohort in Durban, South Africa. Participants were stratified based on stable/increased HbA1c (n = 16) versus decreased HbA1c (n = 46) levels from treatment initiation to 12 month follow-up.
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Results: CD62 P-selectin was up- (1.5-fold) and IL-10 downregulated (0.85-fold) in plasma among individuals whose HbA1c remained stable/increased during TB treatment. This was accompanied by increased pro-inflammatory TB-specific IL-17 production (Th17). In addition, Th1 responses were upregulated in this group, including TNF-α production and CX3CR1 expression, with decreased IL-4 and IL-13 production. Finally, the TNF-α+ IFNγ+ CD8+ T cells were associated with stable/increased HbA1c. These changes were all significantly different in the stable/increased HbA1c relative to the decreased HbA1c group.
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Discussion: Overall, these data suggest that patients with stable/increased HbA1c had an increased pro-inflammatory state. Persistent inflammation and elevated T cell activity in individuals with unresolved dysglycemia following TB treatment may indicate failure to fully resolve infection or may promote persistent dysglycemia in these individuals, and further studies are needed to explore potential mechanisms
Galaxy Zoo: Are Bars Responsible for the Feeding of Active Galactic Nuclei at 0.2 < z < 1.0?
We present a new study investigating whether active galactic nuclei (AGN)
beyond the local universe are preferentially fed via large-scale bars. Our
investigation combines data from Chandra and Galaxy Zoo: Hubble (GZH) in the
AEGIS, COSMOS, and GOODS-S surveys to create samples of face-on, disc galaxies
at 0.2 < z < 1.0. We use a novel method to robustly compare a sample of 120 AGN
host galaxies, defined to have 10^42 erg/s < L_X < 10^44 erg/s, with inactive
control galaxies matched in stellar mass, rest-frame colour, size, Sersic
index, and redshift. Using the GZH bar classifications of each sample, we
demonstrate that AGN hosts show no statistically significant enhancement in bar
fraction or average bar likelihood compared to closely-matched inactive
galaxies. In detail, we find that the AGN bar fraction cannot be enhanced above
the control bar fraction by more than a factor of two, at 99.7% confidence. We
similarly find no significant difference in the AGN fraction among barred and
non-barred galaxies. Thus we find no compelling evidence that large-scale bars
directly fuel AGN at 0.2<z<1.0. This result, coupled with previous results at
z=0, implies that moderate-luminosity AGN have not been preferentially fed by
large-scale bars since z=1. Furthermore, given the low bar fractions at z>1,
our findings suggest that large-scale bars have likely never directly been a
dominant fueling mechanism for supermassive black hole growth.Comment: 13 pages, 5 figures, 2 tables, accepted by MNRA
Global patterns of diapycnal mixing from measurements of the turbulent dissipation rate
The authors present inferences of diapycnal diffusivity from a compilation of over 5200 microstructure profiles. As microstructure observations are sparse, these are supplemented with indirect measurements of mixing obtained from (i) Thorpe-scale overturns from moored profilers, a finescale parameterization applied to (ii) shipboard observations of upper-ocean shear, (iii) strain as measured by profiling floats, and (iv) shear and strain from full-depth lowered acoustic Doppler current profilers (LADCP) and CTD profiles. Vertical profiles of the turbulent dissipation rate are bottom enhanced over rough topography and abrupt, isolated ridges. The geography of depth-integrated dissipation rate shows spatial variability related to internal wave generation, suggesting one direct energy pathway to turbulence. The global-averaged diapycnal diffusivity below 1000-m depth is O(10?4) m2 s?1 and above 1000-m depth is O(10?5) m2 s?1. The compiled microstructure observations sample a wide range of internal wave power inputs and topographic roughness, providing a dataset with which to estimate a representative global-averaged dissipation rate and diffusivity. However, there is strong regional variability in the ratio between local internal wave generation and local dissipation. In some regions, the depth-integrated dissipation rate is comparable to the estimated power input into the local internal wave field. In a few cases, more internal wave power is dissipated than locally generated, suggesting remote internal wave sources. However, at most locations the total power lost through turbulent dissipation is less than the input into the local internal wave field. This suggests dissipation elsewhere, such as continental margins
UV Spectropolarimetry of Narrow-line Radio Galaxies
We present the results of UV spectropolarimetry (2000 - 3000A) and far-UV
spectroscopy (1500 - 2000A) of two low-redshift narrow-line radio galaxies
(NLRGs) taken with the Faint Object Spectrograph onboard the Hubble Space
Telescope (HST). Spectropolarimetry of several NLRGs has shown that, by the
presence of broad permitted lines in polarized flux spectrum, they have hidden
quasars seen through scattered light. Imaging polarimetry has shown that NLRGs
including our targets often have large scattering regions of a few kpc to >~10
kpc scale. This has posed a problem about the nature of the scatterers in these
radio galaxies. Their polarized continuum has the spectral index similar to or
no bluer than that of quasars, which favors electrons as the dominant
scattering particles. The large scattering region size, however, favors dust
scattering, because of its higher scattering efficiency compared to electrons.
In this paper, we investigate the polarized flux spectrum over a wide
wavelength range, combining our UV data with previous optical/infrared
polarimetry data. We infer that the scattering would be often caused by opaque
dust clouds in the NLRGs and this would be a part of the reason for the
apparently grey scattering. In the high-redshift radio galaxies, these opaque
clouds could be the proto-galactic subunits inferred to be seen in the HST
images. However, we still cannot rule out the possibility of electron
scattering, which could imply the existence of a large gas mass surrounding
these radio galaxies.Comment: 25 pages, 21 figures. To appear in Ap
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