Over-reassurance and undersupport after a 'false alarm': a systematic review of the impact on subsequent cancer symptom attribution and help seeking

This literature review examined research into the impact of a previous 'all-clear' or non-cancer diagnosis following symptomatic presentation ('false alarm') on symptom attribution and delays in help seeking for subsequent possible cancer symptoms

Decision-making methods in engineering design: a designer-oriented approach

The use of decisional methods for the solution of engineering design problems has to be tackled on a "human" viewpoint. Hence, fundamental is the identification of design issues and needs that become a designer oriented viewpoint. Decision-based methods are systematically classified in MCDM methods, Structured Design methods and Problem Structuring methods. The results are organised in order to provide a first reference for the designer in a preliminary selection of decision-based methods. The paper shows the heterogeneous use of decision-based methods, traditionally expected to solve only some specific design problems, which have been used also in different design contexts. Moreover, several design issues, which emerged from the review process, have been pointed out and discussed accordingly. This review provided useful results for the enlargement of the state of the art on Decision Based Design methods in engineering design contexts

Evidence for impurity-induced frustration in La2CuO4

Zero-field muon spin rotation and magnetization measurements were performed in La2Cu{1-x}MxO4, for 0<x< 0.12, where Cu2+ is replaced either by M=Zn2+ or by M=Mg2+ spinless impurity. It is shown that while the doping dependence of the sublattice magnetization (M(x)) is nearly the same for both compounds, the N\'eel temperature (T_N(x)) decreases unambiguously more rapidly in the Zn-doped compound. This difference, not taken into account within a simple dilution model, is associated with the frustration induced by the Zn2+ impurity onto the Cu2+ antiferromagnetic lattice. In fact, from T_N(x) and M(x) the spin stiffness is derived and found to be reduced by Zn doping more significantly than expected within a dilution model. The effect of the structural modifications induced by doping on the exchange coupling is also discussed.Comment: 4 pages, 4 figure

The effect of using diesel-biodiesel-bioethanol blends on the fuel feed pump of a small-scale internal combustion engine

Biofuels represent an environmental-friendly and feasible alternative to fossil fuels for internal combustion engines. The use of diesel-biodiesel-bioethanol fuel blends (ternary blends) is one of the most interesting solutions in terms of fossil fuels substitution. They provide an improvement of exhausts gas emissions without any significant sacrifices in terms of energy-conversion efficiency. However, engine operation may be affected by the fuel substitution especially in the auxiliary mechanical fuel-feed systems, traditionally designed for low-density and high-viscosity fossil fuels. In the proposed work, two easy-to-use experimental-based mathematical models have been obtained by using the response surface method to assess the behaviour of fuel feed-pumps when biofuels blends are used. Density and mass flow-rates have been measured for several fuel mixtures and at different temperatures. The proposed equations are intended to be used as a practical tool, based on the optimal behaviour of the fuel feed-pump, in order to choose the best ternary fuel-mixture composition and/or predict/infer the engine performances under non-tested conditions (i.e., other mixtures' compositions and temperatures, however within the inquired domain)

Magnetic order in double-layer manganites (La(1-z)Pr(z))1.2Sr1.8Mn2O7: intrinsic properties and role of the intergrowths

We report on an investigation of the double-layer manganite series (La(1-z)Pr(z))1.2Sr1.8Mn2O7 (0 <= z <= 1), carried out on single crystals by means of both macroscopic magnetometry and local probes of magnetism (muSR, 55Mn NMR). Muons and NMR demonstrate an antiferromagnetically ordered ground state at non-ferromagnetic compositions (z >= 0.6), while more moderate Pr substitutions (0.2 <= z <= 0.4) induce a spin reorientation transition within the ferromagnetic phase. A large magnetic susceptibility is detected at {Tc,TN} < T < 250K at all compositions. From 55Mn NMR spectroscopy, such a response is unambiguously assigned to the intergrowth of a ferromagnetic pseudocubic phase (La(1-z)Pr(z))(1-x)Sr(x)MnO3, with an overall volume fraction estimated as 0.5-0.7% from magnetometry. Evidence is provided for the coupling of the magnetic moments of these inclusions with the magnetic moments of the surrounding (La(1-z)Pr(z))1.2Sr1.8Mn2O7 phase, as in the case of finely dispersed impurities. We argue that the ubiquitous intergrowth phase may play a role in the marked first-order character of the magnetic transition and the metamagnetic properties above Tc reported for double-layer manganites.Comment: 11 pages, 9 figures. Submitted to Phys. Rev.

Evidence for impurity-induced frustration in La2CuO4

Zero-field muon spin rotation and magnetization measurements were performed in La2Cu{1-x}MxO4, for 0<x< 0.12, where Cu2+ is replaced either by M=Zn2+ or by M=Mg2+ spinless impurity. It is shown that while the doping dependence of the sublattice magnetization (M(x)) is nearly the same for both compounds, the N\'eel temperature (T_N(x)) decreases unambiguously more rapidly in the Zn-doped compound. This difference, not taken into account within a simple dilution model, is associated with the frustration induced by the Zn2+ impurity onto the Cu2+ antiferromagnetic lattice. In fact, from T_N(x) and M(x) the spin stiffness is derived and found to be reduced by Zn doping more significantly than expected within a dilution model. The effect of the structural modifications induced by doping on the exchange coupling is also discussed.Comment: 4 pages, 4 figure

A MILP algorithm for the optimal sizing of an off-grid hybrid renewable energy system in South Tyrol

The exploitation of renewable energy sources through sustainable energy technologies are taking the field to decrease the pollutions' emissions into the Earth's environment. To offset the limitations of such resources, hybrid energy systems are becoming fundamental in grid-connected applications as well as in off-grid ones. However, the unsteady behavior of renewable sources, such as Sun and Wind, complicates the prediction of the energy production's trend. The main factors and components involved in the design of hybrid energy systems are: (i) type of generators, (ii) their optimal number, (iii) storage systems and (iv) optimal management strategies. All of them have to be considered simultaneously to develop the optimal solution aimed at either reducing the dependence from fossil fuels or granting the supply of energy. In this paper, a methodology based on the Mixed Integer Linear Programming (MILP) is presented and adopted to meet the electric demand of a mountain lodge located in a remote area in South-Tyrol (Italy). The methodology has been developed implementing an algorithm through the Matlab ©software. The algorithm is capable of evaluating the optimal size of a hybrid off-grid Solar–Wind system with battery storage in order to replace an Internal Combustion Engine (ICE) fueled by diesel. Keywords: Hybrid off-grid energy system, Mixed integer linear programming, Matlab©, Optimization algorithm, Renewable energ

Comparing perceived clarity of information on overdiagnosis used for breast and prostate cancer screening in England: an experimental survey.

OBJECTIVES: 'Overdiagnosis', detection of disease that would never have caused symptoms or death, is a public health concern due to possible psychological and physical harm but little is known about how best to explain it. This study evaluated public perceptions of widely used information on the concept to identify scope for improving communication methods. DESIGN: Experimental survey carried out by a market research company via face-to-face computer-assisted interviews. SETTING: Interviews took place in participants' homes. PARTICIPANTS: 2111 members of the general public in England aged 18-70 years began the survey; 1616 were eligible for analysis. National representativeness was sought via demographic quota sampling. INTERVENTIONS: Participants were allocated at random to receive a brief description of overdiagnosis derived from written information used by either the NHS Breast Screening Programme or the prostate cancer screening equivalent. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was how clear the information was perceived to be (extremely/very clear vs less clear). Other measures included previous exposure to screening information, decision-making styles and demographic characteristics (eg, education). Binary logistic regression was used to assess predictors of perceived clarity. RESULTS: Overdiagnosis information from the BSP was more likely to be rated as more clear compared with the prostate screening equivalent (adjusted OR: 1.43, 95% CI 1.17 to 1.75; p=0.001). Participants were more likely to perceive the information as more clear if they had previously encountered similar information (OR: 1.77, 1.40 to 2.23; p<0.0005) or a screening leaflet (OR: 1.35, 1.04 to 1.74; p=0.024) or had a more 'rational' decision-making style (OR: 1.06, 1.02 to 1.11; p=0.009). CONCLUSIONS: Overdiagnosis information from breast screening may be a useful template for communicating the concept more generally (eg, via organised campaigns). However, this information may be less well-suited to individuals who are less inclined to consider risks and benefits during decision-making