6,121 research outputs found
El ingenioso Hidalgo don Quijote de la Mancha: un acercamiento a través de Gianni Rodari
El trabajo que se presenta a continuación es una propuesta para trabajar una obra de gran importancia para la literatura universal, El Ingenioso Hidalgo Don Quijote de la Mancha, a través de la aplicación de las técnicas propuestas por Gianni Rodari descritas en la Gramática de la Fantasía con el objetivo de integrar el juego en la enseñanza pedagógica de la literatura debido a que la escuela incluye muy poco el juego en su quehacer cotidiano puesto que se ha considerado que no es fundamental para el desarrollo del individuo a pesar de las muchas teorías que argumentan sus aportes a nivel pedagógico y además porque los métodos utilizados en Colombia para la enseñanza de la literatura no son apropiados ya que privilegian la parte gramatical y sintáctica así como los métodos que sesgan la parte estética y creativa de la mismaThe work presented below is a proposal to work a work of great importance to world literature, The Ingenious Hidalgo Don Quixote, through the application of the techniques proposed by Gianni Rodari described in the Grammar of Fantasy with the aim of integrating the game in the pedagogical teaching literature because the school has very little play in their daily work since it has been considered that it is not essential for the development of the individual despite the many theories that argue their contributions to educational level and because the methods used in Colombia for the teaching of literature are not appropriate because grammatical and syntactical favor part and the methods that skew the aesthetic and creative part of i
Potential protective role of reactive astrocytes in the periventricular parenchyma in congenital hydrocephalus
Background
Cerebrospinal fluid accumulation in hydrocephalus produces an elevation of intraventricular pressure with pathological consequences on the periventricular brain parenchyma including ischemia, oedema, oxidative stress, and accumulation of metabolic waste products. Here we studied in the hyh mouse, an animal model of congenital hydrocephalus, the role of reactive astrocytes in this clinical degenerative condition.
Materials and Methods
Wild type and hydrocephalic hyh mice at 30 days of postnatal age were used. Three metabolites related to the oxidative and neurotoxic conditions were analysed in ex vivo samples (glutathione, glutamine and taurine) using High Resolution Magic Angle Spinning (HR-MAS). Glutathione synthetase and peroxidase, glutamine synthetase, kidney-type glutaminase (KGA), and taurine/taurine transporter were immunolocated in brain sections.
Results
Levels of the metabolites were remarkably higher in hydrocephalic conditions. Glutathione peroxidase and synthetase were both detected in the periventricular reactive astrocytes and neurons. Taurine was mostly found free in the periventricular parenchyma and in the reactive astrocytes, and the taurine transporter was mainly present in the neurons located in such regions. Glutamine synthetase was found in reactive astrocytes. Glutaminase was also detected in the reactive astrocytes and in periventricular neurons. These results suggest a possible protective response of reactive astrocytes against oxidative stress and neurotoxic conditions.
Conclusions
Astrocyte reaction seems to trigger an anti-oxidative and anti-neurotoxic response in order to ameliorate pathological damage in periventricular areas of the hydrocephalic mice.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. PI15-00619 to AJJ
Thermochemical Energy Storage with Integrated District Heat Production—A Case Study of Swede
The implementation of electricity-charged thermochemical energy storage (TCES) using high-temperature solid cycles would benefit the energy system by enabling the absorption of variable renewable energy (VRE) and its conversion into dispatchable heat and power. Using a Swedish case study, this paper presents a process for TCES-integrated district heating (DH) production, assesses its technical suitability, and discusses some practical implications and additional implementation options. The mass and energy flows of a biomass plant retrofitted with an iron-based redox loop are calculated for nine specific scenarios that exemplify its operation under electricity generation mixes that differ with respect to variability and price. In addition, the use of two types of electrolyzers (low-temperature and high-temperature versions) is investigated. The results show that for the Swedish case, the proposed scheme is technically feasible and capable of covering the national DH demand by making use of the existing DH plants, with an estimated process energy efficiency (electricity to heat) of 90%. The results also show that for a retrofit of the entire Swedish DH fleet, the required inventories of iron are approximately 2.8 Mt for the intermediate scenario, which represents 0.3% and 11.0% of the national reserves and annual metallurgical production rates of the national industry, respectively. In addition to the dispatchable heat, the process generates a significant amount of nondispatchable heat, especially for the case that employs low-temperature electrolyzers. This added generation capacity allows the process to cover the heat demand while decreasing the maximum capacity of the charging side computed herein
Thermochemical Energy Storage with Integrated District Heat Production—A Case Study of Swede
The implementation of electricity-charged thermochemical energy storage (TCES) using high-temperature solid cycles would benefit the energy system by enabling the absorption of variable renewable energy (VRE) and its conversion into dispatchable heat and power. Using a Swedish case study, this paper presents a process for TCES-integrated district heating (DH) production, assesses its technical suitability, and discusses some practical implications and additional implementation options. The mass and energy flows of a biomass plant retrofitted with an iron-based redox loop are calculated for nine specific scenarios that exemplify its operation under electricity generation mixes that differ with respect to variability and price. In addition, the use of two types of electrolyzers (low-temperature and high-temperature versions) is investigated. The results show that for the Swedish case, the proposed scheme is technically feasible and capable of covering the national DH demand by making use of the existing DH plants, with an estimated process energy efficiency (electricity to heat) of 90%. The results also show that for a retrofit of the entire Swedish DH fleet, the required inventories of iron are approximately 2.8 Mt for the intermediate scenario, which represents 0.3% and 11.0% of the national reserves and annual metallurgical production rates of the national industry, respectively. In addition to the dispatchable heat, the process generates a significant amount of nondispatchable heat, especially for the case that employs low-temperature electrolyzers. This added generation capacity allows the process to cover the heat demand while decreasing the maximum capacity of the charging side computed herein
Data on the diagnosis of the management of the primary waste from electrical and electronic equipment in health care institutions in Barranquilla, Colombia
Economic and technological development advances exponentially, and the implementation of new technologies in the health sector has become a source of waste for electrical and electronic equipment (WEEE). Electrical and electronic equipment must be replaced periodically, either due to a technological update or to improve medical treatments, which ultimately leads to the generation of this type of waste. This work aimed to conduct exploratory research on the current situation of the handling of this type of waste in Barranquilla, Colombia, considering the limited information related to the management of biomedical WEEE in the city. Sixty health care institutions (HCIs), including hospitals and clinics, odontological centres and ophthalmological centres, participated favourably in the surveys concerning the management of WEEE. Through this work, it was possible to establish a working staff level of knowledge on WEEE disposal and the framework for the management and temporary collection of this waste. Therefore, the data are useful for proposing strategies for the integral management of electrical and electronic waste in both small and large populations
Force-Velocity Profile of Competitive Kayakers: Evaluation of a Novel Single Kayak Stroke Test
The assessment of the force-velocity (F-V) profile in athletes may have important applications for training prescription, injury management, and fatigue monitoring. This study aimed to assess whether a novel single kayak stroke test (SKST) is able to provide the F-V relationship variables (maximum force, maximum velocity and maximum power) of competitive kayakers with acceptable reliability and external validity. Six female (age: 20.3 ± 3.7 years) and eight male (age: 20.8 ± 2.4 years) elite kayakers performed the SKST, bench press, bench pull, and short Wingate kayak test. The individual F-V relationships were highly linear [median r (range): left stroke = 0.986 (0.897 - 0.998); right stroke = 0.987 (0.971 - 0.999)]. The reliability of the F-V relationship parameters obtained during the SKST was high (within-session: CV ≤ 4.48% and ICC ≥ 0.93; between-session: CV ≤ 8.06% and ICC ≥ 0.65). The validity of the F-V relationship parameters obtained during the SKST was generally very high for maximum power (r range = 0.825 - 0.975), high for maximum force during both the bench press and the bench pull (r range = 0.751 - 0.831), and high or moderate for maximal velocity during the bench pull (r = 0.770 - 0.829) and the bench press (r = 0.355 - 0.471), respectively. The SKST can be considered a feasible procedure for testing the maximal upper-body muscle mechanical capacities of kayakers
Producción más limpia como alternativa de desarrollo sostenible de las explotaciones de arcilla en la vereda las casitas del municipio de Valledupar
Con el desarrollo de esta investigación se estudia la implementación de la estrategia preventiva de producción más limpia, como alternativa de desarrollo sostenible de las explotaciones de arcilla en la vereda las casitas del municipio de Valledupar, apuntando a la concienciación frente al deterioro de la vegetación, la disponibilidad del recurso hídrico y la pérdida de valor del suelo de esta comunidad. La herramienta de producción más limpia está orientada hacia procesos productivos, productos y servicio; con el fin de fortalecer la competitividad empresarial mediante innovaciones tecnológicas, reducción de costos y disminución de riesgos en aspectos de seguridad, salud humana y medio ambiente.Declaración: EL AUTOR-ESTUDIANTE, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto, la obra es de su exclusiva autoría y tiene la titularidad sobre la misma. PARÁGRAFO: en caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL ESTUDIANTE-AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la Fundación Universitaria del Área Andina actúa como un tercero de buena fe
Improving the understanding of web user behaviors through machine learning analysis of eye-tracking data
Eye-tracking techniques are widely used to analyze user behavior. While eye-trackers collect valuable quantitative data, the results are often described in a qualitative manner due to the lack of a model that interprets the gaze trajectories generated by routine tasks, such as reading or comparing two products. The aim of this work is to propose a new quantitative way to analyze gaze trajectories (scanpaths) using machine learning. We conducted a within-subjects study (N = 30) testing six different tasks that simulated specific user behaviors in web sites (attentional, comparing two images, reading in different contexts, and free surfing). We evaluated the scanpath results with three different classifiers (long short-term memory recurrent neural network—LSTM, random forest, and multilayer perceptron neural network—MLP) to discriminate between tasks. The results revealed that it is possible to classify and distinguish between the 6 different web behaviors proposed in this study based on the user’s scanpath. The classifier that achieved the best results was the LSTM, with a 95.7% accuracy. To the best of our knowledge, this is the first study to provide insight about MLP and LSTM classifiers to discriminate between tasks. In the discussion, we propose practical implications of the study results
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