Natural variability of lotic Mediterranean ecosystems or wildfire perturbations: who will win?

This study evaluates the impacts of wildfires in lotic Mediterranean ecosystems. It was carried out at Monchique ridge after big wildfires occurred during 2002 and 2003. Deferential impacts were evaluated comparing historical results obtained before the wildfires (1999 and 2001), with the post fire ones (2006 and 2007). Physical and chemical parameters of the water, habitat morphology, diatoms, macrophytes, macroinvertebrates and fishes were evaluated at 10 collecting places, before and after wildfires. High recovering rates were observed to the vegetation, but it is still possible to found fire impacts over macrophytes and river morphology. Wildfires, contributed to canopy decrease and, consequently to the growth of plants that usually are controlled by shadow. As a result, vegetation biodiversity tend to increase. River banks tend also to be invaded by terrestrial plants. Higher post fires recover rates were observed to the more aquatic communities (diatoms, macroinvertebrates and fishes). For those communities, comparing spring situations before and after the fires no substantial differences were observed. Sometimes differences between consecutive years are even higher. So it can be concluded that magnitude of wildfire impacts is less than the natural inter-annual variability of Mediterranean rivers. Long-term effects of forest fires, resulting from large woody debries, were also detected by morphological alterations, like debries dams. Habitat diversity increase and impacts on aquatic communities are expected

Foeniculum vulgare Essential Oils: Chemical Composition, Antioxidant and Antimicrobial Activities

The essential oils from Foeniculum vulgare commercial aerial parts and fruits were isolated by hydrodistillation, with different distillation times (30 min, I h, 2 h and 3 h), and analyzed by GC and GC-MS. The antioxidant ability was estimated using four distinct methods. Antibacterial activity was determined by the agar diffusion method. Remarkable differences, and worrying from the quality and safety point of view, were detected in the essential oils. trans-Anethole (31-36%), alpha-pinene (14-20%) and limonene (11-13%) were the main components of the essentials oil isolated from F. vulgare dried aerial parts, whereas methyl chavicol (= estragole) (79-88%) was dominant in the fruit oils. With the DPPH method the plant oils showed better antioxidant activity than the fruits oils. With the TBARS method and at higher concentrations, fennel essential oils showed a pro-oxidant activity. None of the oils showed a hydroxyl radical scavenging capacity >50%, but they showed an ability to inhibit 5-lipoxygenase. The essential oils showed a very low antimicrobial activity. In general, the essential oils isolated during 2 h were as effective, from the biological activity point of view, as those isolated during 3 h.info:eu-repo/semantics/publishedVersio

Comparative evolutionary genomics of the HADH2 gene encoding Aβ-binding alcohol dehydrogenase/17β-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10)

BACKGROUND: The Aβ-binding alcohol dehydrogenase/17β-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10) is an enzyme involved in pivotal metabolic processes and in the mitochondrial dysfunction seen in the Alzheimer's disease. Here we use comparative genomic analyses to study the evolution of the HADH2 gene encoding ABAD/HSD10 across several eukaryotic species. RESULTS: Both vertebrate and nematode HADH2 genes showed a six-exon/five-intron organization while those of the insects had a reduced and varied number of exons (two to three). Eutherian mammal HADH2 genes revealed some highly conserved noncoding regions, which may indicate the presence of functional elements, namely in the upstream region about 1 kb of the transcription start site and in the first part of intron 1. These regions were also conserved between Tetraodon and Fugu fishes. We identified a conserved alternative splicing event between human and dog, which have a nine amino acid deletion, causing the removal of the strand β(F). This strand is one of the seven strands that compose the core β-sheet of the Rossman fold dinucleotide-binding motif characteristic of the short chain dehydrogenase/reductase (SDR) family members. However, the fact that the substrate binding cleft residues are retained and the existence of a shared variant between human and dog suggest that it might be functional. Molecular adaptation analyses across eutherian mammal orthologues revealed the existence of sites under positive selection, some of which being localized in the substrate-binding cleft and in the insertion 1 region on loop D (an important region for the Aβ-binding to the enzyme). Interestingly, a higher than expected number of nonsynonymous substitutions were observed between human/chimpanzee and orangutan, with six out of the seven amino acid replacements being under molecular adaptation (including three in loop D and one in the substrate binding loop). CONCLUSION: Our study revealed that HADH2 genes maintained a reasonable conserved organization across a large evolutionary distance. The conserved noncoding regions identified among mammals and between pufferfishes, the evidence of an alternative splicing variant conserved between human and dog, and the detection of positive selection across eutherian mammals, may be of importance for further research on ABAD/HSD10 function and its implication in the Alzheimer's disease

Carelessness and Affect in an Intelligent Tutoring System for Mathematics

We investigate the relationship between students’ affect and their frequency of careless errors while using an Intelligent Tutoring System for middle school mathematics. A student is said to have committed a careless error when the student’s answer is wrong despite knowing the skill required to provide the correct answer. We operationalize the probability that an error is careless through the use of an automated detector, developed using educational data mining, which infers the probability that an error involves carelessness rather than not knowing the relevant skill. This detector is then applied to log data produced by high-school students in the Philippines using a Cognitive Tutor for scatterplots. We study the relationship between carelessness and affect, triangulating between the detector of carelessness and field observations of affect. Surprisingly, we find that carelessness is common among students who frequently experience engaged concentration. This finding implies that a highly engaged student may paradoxically become overconfident or impulsive, leading to more careless errors. In contrast, students displaying confusion or boredom make fewer careless errors. Further analysis over time suggests that confused and bored students have lower learning overall. Thus, their mistakes appear to stem from a genuine lack of knowledge rather than carelessness

Goat Kidding Dataset

The detection of kidding in production animals is of the utmost importance, given the frequency of problems associated with the process, and the fact that timely human help can be a safeguard for the well-being of the mother and kid. The continuous human monitoring of the process is expensive, given the uncertainty of when it will occur, so the establishment of an autonomous mechanism that does so would allow calling the human responsible who could intervene at the opportune moment. The present dataset consists of data from the sensorization of 16 pregnant and two non-pregnant Charnequeira goats, during a period of four weeks, the kidding period. The data include measurements from neck to floor height, measured by ultrasound and accelerometry data measured by an accelerometer existing at the monitoring collar. Data was continuously sampled throughout the experiment every 10 s. The goats were monitored both in the goat shelter (day and night) and during the grazing period in the pasture. The births of the animals were also registered, both in terms of the time at which they took place, but also with details regarding how they took place and the number of offspring, and notes were also added.info:eu-repo/semantics/publishedVersio

Sheep Nocturnal Activity Dataset

Monitoring sheep’s behavior is of paramount importance, because deviations from normal patterns may indicate nutritional, thermal or social stress, changes in reproductive status, health issues, or predator attacks. The night period, despite being a more restful period in which animals are theoretically sleeping and resting, represents approximately half of the life cycle of animals; therefore, its study is of immense interest. Wearable sensors have become a widely recognized technique for monitoring activity, both for their precision and the ease with which the sensorized data can be analyzed. The present dataset consists of data from the sensorization of 18 Serra da Estrela sheep, during the nocturnal period between 18 November 2021 and 16 February 2022. The data contain measurements taken by ultrasound and accelerometry of the height from neck to ground, as well as measurements taken by an accelerometer in the monitoring collar. Data were collected every 10 s when the animals were in the shelter. With the collection of data from various sensors, active and inactive periods can be identified throughout the night, quantifying the number and average time of those periods.info:eu-repo/semantics/publishedVersio

¿Consumen más drogas los adolescentes con déficit en habilidades sociales?

Durante la adolescencia es común que se manifiesten conductas de riesgo para la salud entre las que destaca el uso de drogas. El déficit en habilidades sociales es uno de los factores de riesgo señalado por los modelos teóricos sobre el inicio del consumo. El objetivo de este estudio es aportar datos empíricos sobre la relación entre las habilidades sociales y el consumo de sustancias psicoactivas en población adolescente española. Se pretende además examinar las diferencias en este factor de riesgo en función de la edad y el sexo. Participaron 1.688 estudiantes españoles de secundaria con edades comprendidas entre 13 y 17 años que informaron sobre sus hábitos de consumo y su competencia social. Los resultados indicaron una clara relación entre las habilidades sociales y el consumo de sustancias. La conducta antisocial está asociada al consumo de alcohol y cannabis. Los varones puntúan en mayor medida en conducta agresiva/ antisocial, orgullo/arrogancia y soledad/ansiedad social. Los resultados confirman la importancia de prevenir el consumo de sustancias de forma selectiva con adolescentes que presenten conductas sociales inadecuadasDuring adolescence risk behaviors for health are common, including drug use. A deficit in social skills is one of the risk factors identified by the theoretical models of initiation to consumption. The aim of this study is to provide empirical data on the relationship between social skills and the use of psychoactive substances in Spanish adolescents. It also aims to examine the differences in this risk factor in terms of age and sex. 1,688 high school Spanish students aged between 13 and 17 years reported their consumption habits and their social competence. The results indicated a clear relationship between social skills and substance use. Antisocial behavior is associated with alcohol and cannabis. Males scored more on aggressive/antisocial behavior, pride/arrogance and loneliness/social anxiety. The results confirm the importance of selectively preventing consumption of substances among adolescents with inappropriate social behavior

Can the integration of multiple biomarkers and sediment geochemistry aid solving the complexity of sediment risk assessment?: a case study with a benthic fish

Surveying toxicity of complex geochemical media as aquatic sediments often yields results that are either difficult to interpret or even contradictory to acknowledged theory. Multi-level biomarkers were investigated in a benthic fish exposed to estuarine sediments through laboratory and in situ bioassays, to evaluate their employment either in ecological risk assessment or in more mechanistic approaches to assess sediment-bound toxicity. Biomarkers reflecting lesions (such as genotoxicity or histopathology), regardless of their low or absent specificity to contaminants, are efficient in segregating exposure to contaminated from uncontaminated sediments even when classical biomarkers like CYP1A and metallothionein induction are inconclusive. Conversely, proteomics and gene transcription analyses provided information on the mechanics of toxicity and aided explaining response variation as a function of metabolic imbalance and impairment of defences against insult. In situ bioassays, although less expedite and more affected by confounding factors, produced data better correlated to overall sediment contamination.info:eu-repo/semantics/publishedVersio

Developing a new simulation and visualization platform for researching aspects of mobile network performance

Nowadays, mobile networks represent one of the most innovative and challenging technological and research-oriented fields of work. The growth on user subscriptions and the advances introduced by Artificial Intelligence (AI) and Internet of Things (IoT), greatly enhanced the complexity and potential of communication networks. The increase on variety of devices and exchanged mobile data traffic resulted in demanding requirements for the network providers. As networks tend to scale and data to increase, some problems start to arise. Traffic congestion, packet loss and high latency being some examples. Therefore, it is important to introduce powerful tools and methods to tackle these challenges. On this perspective, several studies have highlighted AI systems, mainly Machine Learning (ML) algorithms, as the most promising methods, in the context of wireless networks, by improving the overall performance and efficiency. This work proposes to integrate several network optimization algorithms, already developed, in a common and unified visualization platform. These algorithms were developed in C# and Python and some of them use supervised and unsupervised ML techniques. The proposed solution includes multi-threading processes to deal with concurrent simulations, a proxy to communicate between platforms and a dynamic visual interface.info:eu-repo/semantics/publishedVersio

Telemedicine in COPD: An Overview by Topics

Introduction: COPD is a major cause of morbidity and mortality worldwide and carries a huge and growing economic and social burden. Telemedicine might allow the care of patients with limited access to health services and improve their self-management. During the COVID-19 pandemic, patient's safety represents one of the main reasons why we might use these tools to manage our patients. The authors conducted a literature search in MEDLINE database. The retrieval form of the Medical Subject Headings (Mesh) was ((Telemedicine OR Tele-rehabilitation OR Telemonitoring OR mHealth OR Ehealth OR Telehealth) AND COPD). We only included systematic reviews, reviews, meta-analysis, clinical trials and randomized-control trials, in the English language, with the selected search items in title or abstract, and published from January 1st 2015 to 31st May 2020 (n = 56). There was a positive tendency toward benefits in tele-rehabilitation, health-education and self-management, early detection of COPD exacerbations, psychosocial support and smoking cessation, but the heterogeneity of clinical trials and reviews limits the extent to which this value can be understood. Telemonitoring interventions and cost-effectiveness had contradictory results. The literature on teleconsultation was scarce during this period. The non-inferiority tendency of telemedicine programmes comparing to conventional COPD management seems an opportunity to deliver quality healthcare to COPD patients, with a guarantee of patient's safety, especially during the COVID-19 outbreak.info:eu-repo/semantics/publishedVersio