116 research outputs found
How to Evaluate Students’ Entrepreneurial Projects? International Experience and Recommendations for Application in Russia
Quality assessment of entrepreneurship education and its’ results is an important problem in higher education. The task becomes even more relevant with the necessity of technological modernization in times of economic crisis. In particular, it is necessary to develop a system of criteria that would not only serve educational purposes, but also simulate the emerging of new market enterprises, which remains problematic so far now, despite the active measures from the government to support student initiatives. The lack of attention towards contemporary international ratings in the field of startup evaluation appears to be a significant limitation. Analysis of the related field will help with defining the criteria for entrepreneurial project assessment. The present paper aims to fill this gap. As a result, suggestions for projects’ evaluation were developed that include both financial and non-financial criteria, applicable to the student initiatives, and taking into account their specifics
Monotherapy with pixantrone in histologically confirmed relapsed or refractory aggressive B-cell non-Hodgkin lymphoma: post-hoc analyses from a phase III trial.
This post hoc analysis of a phase 3 trial explored the effect of pixantrone in patients (50 pixantrone, 47 comparator) with relapsed or refractory aggressive B-cell non-Hodgkin lymphoma (NHL) confirmed by centralized histological review. Patients received 28-d cycles of 85 mg/m(2) pixantrone dimaleate (equivalent to 50 mg/m(2) in the approved formulation) on days 1, 8 and 15, or comparator. The population was subdivided according to previous rituximab use and whether they received the study treatment as 3rd or 4th line. Median number of cycles was 4 (range, 2-6) with pixantrone and 3 (2-6) with comparator. In 3rd or 4th line, pixantrone was associated with higher complete response (CR) (23·1% vs. 5·1% comparator, P = 0·047) and overall response rate (ORR, 43·6% vs. 12·8%, P = 0·005). In 3rd or 4th line with previous rituximab (20 pixantrone, 18 comparator), pixantrone produced better ORR (45·0% vs. 11·1%, P = 0·033), CR (30·0% vs. 5·6%, P = 0·093) and progression-free survival (median 5·4 vs. 2·8 months, hazard ratio 0·52, 95% confidence interval 0·26-1·04) than the comparator. Similar results were found in patients without previous rituximab. There were no unexpected safety issues. Pixantrone monotherapy is more effective than comparator in relapsed or refractory aggressive B-cell NHL in the 3rd or 4th line setting, independently of previous rituximab
FG Sge: new multicolor photometry and short-term dust shell clearing in 2019
We present the results of a new stage of the long-term photometric study of
FG Sge which is a quickly evolving central star of the planetary nebula Hen
1-5. Our new observations carried out on the SAI MSU telescopes in the optical
() and infrared (IR) () regions in 2008-2021 and 2013-2021,
respectively, allowed us to trace the evolution of the star's brightness in
recent years. The most significant observations were performed in 2019 when the
star suffered a short clearing of the dust shell and became visible in .
Based on the spectral energy distribution of FG Sge in the 0.4-5 m
wavelength range we derived the dust shell parameters: the size of dust grains
m, the inner radius temperature K, optical
depth (), the total mass of dust
. After the short-term clearing of the
dust shell in 2019, another dust structure was ejected that resulted in the
star fading in all the observed bands. Based on the IR brightness and color
curves, we estimated the dust depth growth in 2019-2020.Comment: 17 pages, 9 figures, 3 tables. Accepted for publication in Astronomy
Letter
Energy transfer in Tm,Ho:KYW crystal and diode-pumped microchip laser operation
An investigation of Tm-Ho energy transfer in Tm(5at.%), Ho(0.4at.%):KYW single crystal by two independent techiques was performed. Based on fluorescence dynamics measurements, energy transfer parameters P71 and P28 for direct (Tm→Ho) and back (Ho→Tm) transfers, respectively, as well as equilibrium constant Θ were evaluated. The obtained results were supported by calculation of microscopic interaction parameters according to the Förster-Dexter theory for a dipoledipole interaction. Diode-pumped continuous-wave operation of Tm,Ho:KYW microchip laser was demonstrated, for the first time to our knowledge. Maximum output power of 77 mW at 2070 nm was achieved at the fundamental TEM00 mode
Anisotropic optical properties of single-crystal GdBa2Cu3O7-delta
The optical spectrum of reduced-T(c) GdBa2Cu3O7-delta has been measured for polarizations parallel and perpendicular to the ab plane. The sample was an oxygen-deficient single crystal with a large face containing the c axis. The polarized reflectance from this face was measured from 20-300 K in the spectral region from 30-3000 cm-1, with 300 K data to 30 000 cm-1. Kramers-Kronig analysis was used to determine the spectral dependence of the ab and the c components of the dielectric tensor. The optical properties are strongly anisotropic. The ab-plane response resembles that of other reduced-T(c) materials whereas the c axis, in contrast, shows only the presence of several phonons. There is a complete absence of charge carrier response along c above and below T(c). This observation allows us to set an upper limit to the free-carrier spectral weight for transport perpendicular to the CuO2 planes
Systematics of Inclusive Photon Production in 158 AGeV Pb Induced Reactions on Ni, Nb, and Pb Targets
The multiplicity of inclusive photons has been measured on an event-by-event
basis for 158 AGeV Pb induced reactions on Ni, Nb, and Pb targets. The
systematics of the pseudorapidity densities at midrapidity (rho_max) and the
width of the pseudorapidity distributions have been studied for varying
centralities for these collisions. A power law fit to the photon yield as a
function of the number of participating nucleons gives a value of 1.13+-0.03
for the exponent. The mean transverse momentum, , of photons determined
from the ratio of the measured electromagnetic transverse energy and photon
multiplicity, remains almost constant with increasing rho_max. Results are
compared with model predictions.Comment: 16 pages including 4 figure
Scaling of Particle and Transverse Energy Production in 208Pb+208Pb collisions at 158 A GeV
Transverse energy, charged particle pseudorapidity distributions and photon
transverse momentum spectra have been studied as a function of the number of
participants (N_{part}) and the number of binary nucleon-nucleon collisions
(N_{coll}) in 158 A GeV Pb+Pb collisions over a wide impact parameter range. A
scaling of the transverse energy pseudorapidity density at midrapidity as
N_{part}^{1.08 \pm 0.06} and N_{coll}^{0.83 \pm 0.05} is observed. For the
charged particle pseudorapidity density at midrapidity we find a scaling as
N_{part}^{1.07 \pm 0.04} and N_{coll}^{0.82 \pm 0.03}. This faster than linear
scaling with N_{part} indicates a violation of the naive Wounded Nucleon Model.Comment: 13 pages, 16 figures, submitted to European Physical Journal C
(revised results for scaling exponents
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