Can Gravity Distinguish Between Dirac and Majorana Neutrinos?

We show that spin-gravity interaction can distinguish between Dirac and Majorana neutrino wave packets propagating in a Lense-Thirring background. Using time-independent perturbation theory and gravitational phase to generate a perturbation Hamiltonian with spin-gravity coupling, we show that the associated matrix element for the Majorana neutrino differs significantly from its Dirac counterpart. This difference can be demonstrated through significant gravitational corrections to the neutrino oscillation length for a two-flavour system, as shown explicitly for SN1987A.Comment: 4 pages, 2 figures; minor changes of text; typo corrected; accepted in Physical Review Letter

Lower Neutrino Mass Bound from SN1987A Data and Quantum Geometry

A lower bound on the light neutrino mass $m_\nu$ is derived in the framework of a geometrical interpretation of quantum mechanics. Using this model and the time of flight delay data for neutrinos coming from SN1987A, we find that the neutrino masses are bounded from below by $m_\nu\gtrsim 10^{-4}-10^{-3}$eV, in agreement with the upper bound $m_\nu\lesssim$ $({\cal O}(0.1) - {\cal O} (1))$ eV currently available. When the model is applied to photons with effective mass, we obtain a lower limit on the electron density in intergalactic space that is compatible with recent baryon density measurements.Comment: 22 pages, 3 figure

Use of thyroid hormones in hypothyroid and euthyroid patients: A survey of members of the Endocrine Society of Australia

\ua9 2024 The Authors. Clinical Endocrinology published by John Wiley & Sons Ltd.Objective: Hypothyroidism is a common endocrine condition usually managed with levothyroxine (LT4). However, controversy remains around the use of liothyronine (LT3). We aimed to investigate the practices of Australian endocrinologists when managing patients with hypothyroidism, their use of LT3 + LT4 combination therapy and use of thyroid hormones in euthyroid patients. Design and Participants: Members of the Endocrine Society of Australia (ESA) were invited to participate in an online questionnaire. Measurements: We analysed questionnaires that had complete demographic data. Results: Eighty-seven questionnaires fulfilled the criteria. LT4 was used as first line treatment for hypothyroidism by all respondents. Only 45% reported that their patients were dispensed the brand of LT4 that they recommend. LT3 (alone or in combination) was prescribed by 44% in their clinical practice. Although 49% of respondents would consider LT3 + LT4 in patients with normal TSH who had ongoing symptoms of hypothyroidism, the inability of LT4 to restore normal physiology was ranked the least likely explanation for persistent symptoms and only 32% would consider it for themselves if they were diagnosed with hypothyroidism. The majority (55%), in accordance with evidence, would not prescribe thyroid hormone to euthyroid individuals but 39% would consider use in euthyroid female infertility with high levels of thyroid antibodies and 11% in euthyroid patients with a simple goitre growing over time. LT4 use in pregnancy was variable among members. Conclusions: Australian endocrinologists mostly follow international guidelines when prescribing thyroid hormone therapy and many prescribe combination LT3 and LT4 therapy, particularly for patients who remain symptomatic on LT4 monotherapy. Prescribing practices are largely similar to other countries who have completed similar questionnaires

Incentive or Habit Learning in Amphibians?

Toads (Rhinella arenarum) received training with a novel incentive procedure involving access to solutions of different NaCl concentrations. In Experiment 1, instrumental behavior and weight variation data confirmed that such solutions yield incentive values ranging from appetitive (deionized water, DW, leading to weight gain), to neutral (300 mM slightly hypertonic solution, leading to no net weight gain or loss), and aversive (800 mM highly hypertonic solution leading to weight loss). In Experiment 2, a downshift from DW to a 300 mM solution or an upshift from a 300 mM solution to DW led to a gradual adjustment in instrumental behavior. In Experiment 3, extinction was similar after acquisition with access to only DW or with a random mixture of DW and 300 mM. In Experiment 4, a downshift from DW to 225, 212, or 200 mM solutions led again to gradual adjustments. These findings add to a growing body of comparative evidence suggesting that amphibians adjust to incentive shifts on the basis of habit formation and reorganization

Spin-gravity coupling and gravity-induced quantum phases

External gravitational fields induce phase factors in the wave functions of particles. The phases are exact to first order in the background gravitational field, are manifestly covariant and gauge invariant and provide a useful tool for the study of spin-gravity coupling and of the optics of particles in gravitational or inertial fields. We discuss the role that spin-gravity coupling plays in particular problems.Comment: 18 pages, 1 figur

A simple synthesis of N-perfluoroacylated and N-acylated glycals of neuraminic acid with a cyclic aminic substituent at the 4\u3b1 position as possible inhibitors of sialidases

A simple protocol for the synthesis of N-perfluoroacylated and N-acylated glycals of neuraminic acid, having a secondary cyclic amines (morpholine or piperidine) at the 4\u3b1 position, has been set-up, starting from peracetylated N-acetylneuraminic acid methyl ester that undergoes, sequencially to its direct N-transacylation followed by a C-4 amination, a \u3b2-elimination, and a selective hydrolysis of the ester functions, without affecting the sensitive perfluorinated amid

The Cosmic-Ray Proton and Helium Spectra measured with the CAPRICE98 balloon experiment

A new measurement of the primary cosmic-ray proton and helium fluxes from 3 to 350 GeV was carried out by the balloon-borne CAPRICE experiment in 1998. This experimental setup combines different detector techniques and has excellent particle discrimination capabilities allowing clear particle identification. Our experiment has the capability to determine accurately detector selection efficiencies and systematic errors associated with them. Furthermore, it can check for the first time the energy determined by the magnet spectrometer by using the Cherenkov angle measured by the RICH detector well above 20 GeV/n. The analysis of the primary proton and helium components is described here and the results are compared with other recent measurements using other magnet spectrometers. The observed energy spectra at the top of the atmosphere can be represented by (1.27+-0.09)x10^4 E^(-2.75+-0.02) particles (m^2 GeV sr s)^-1, where E is the kinetic energy, for protons between 20 and 350 GeV and (4.8+-0.8)x10^2 E^(-2.67+-0.06) particles (m^2 GeV nucleon^-1 sr s)^-1, where E is the kinetic energy per nucleon, for helium nuclei between 15 and 150 GeV nucleon^-1.Comment: To be published on Astroparticle Physics (44 pages, 13 figures, 5 tables

A Multicentric, Single Arm, Prospective, Stratified Clinical Investigation to Confirm MammoWave’s Ability in Breast Lesions Detection

Novel techniques, such as microwave imaging, have been implemented in different prototypes and are under clinical validation, especially for breast cancer detection, due to their harmless technology and possible clinical advantages over conventional imaging techniques. In the prospective study presented in this work, we aim to investigate through a multicentric European clinical trial (ClinicalTrials.gov Identifier NCT05300464) the effectiveness of the MammoWave microwave imaging device, which uses a Huygens-principle-based radar algorithm for image reconstruction and comprises dedicated image analysis software. A detailed clinical protocol has been prepared outlining all aspects of this study, which will involve adult females having a radiologist study output obtained using conventional exams (mammography and/or ultrasound and/or magnetic resonance imaging) within the previous month. A maximum number of 600 volunteers will be recruited at three centres in Italy and Spain, where they will be asked to sign an informed consent form prior to the MammoWave scan. Conductivity weighted microwave images, representing the homogeneity of the tissues’ dielectric properties, will be created for each breast, using a conductivity = 0.3 S/m. Subsequently, several microwave image parameters (features) will be used to quantify the images’ non-homogenous behaviour. A selection of these features is expected to allow for distinction between breasts with lesions (either benign or malignant) and those without radiological findings. For all the selected features, we will use Welch’s t-test to verify the statistical significance, using the gold standard output of the radiological study review

Pseudo-unitary symmetry and the Gaussian pseudo-unitary ensemble of random matrices

Employing the currently discussed notion of pseudo-Hermiticity, we define a pseudo-unitary group. Further, we develop a random matrix theory which is invariant under such a group and call this ensemble of pseudo-Hermitian random matrices as the pseudo-unitary ensemble. We obtain exact results for the nearest-neighbour level spacing distribution for (2 X 2) PT-symmetric Hamiltonian matrices which has a novel form, s log (1/s) near zero spacing. This shows a level repulsion in marked distinction with an algebraic form in the Wigner surmise. We believe that this paves way for a description of varied phenomena in two-dimensional statistical mechanics, quantum chromodynamics, and so on.Comment: 9 pages, 2 figures, LaTeX, submitted to the Physical Review Letters on August 20, 200