Tamarind water catalyzed improved synthesis of 2,2ʹ-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives: A green approach

294-299The reaction of 5,5-dimethyl-1,3-cyclohexanedione (dimedone) with various aromatic aldehydes catalyzed by tamarind water produces 2,2ʹ-arylmethylenebis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives in 85-98% yield under water bath heating at 60°C. Xanthene derivatives as cyclized products have not been obtained by this procedure. This method provides several advantages such as environmental friendliness, high yields and simple work-up procedure. The product is purified by simple filtration followed by crystallization with ethanol and drying processes

Tamarind water catalyzed improved synthesis of 2,2ʹ-arylmethylenebis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives: A green approach

The reaction of 5,5-dimethyl-1,3-cyclohexanedione (dimedone) with various aromatic aldehydes catalyzed by tamarindwater produces 2,2ʹ-arylmethylenebis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives in 85-98% yield underwater bath heating at 60°C. Xanthene derivatives as cyclized products have not been obtained by this procedure.This method provides several advantages such as environmental friendliness, high yields and simple work-up procedure.The product is purified by simple filtration followed by crystallization with ethanol and drying processes

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Tamarind fruit juice as a natural catalyst: An excellent catalyst for efficient and green synthesis of bis-, tris-, and tetraindolyl compounds in water

763-768An efficient and greener synthesis of bis-, and tris(indolyl)-methanes and synthesis of di-bis(indolyl)methanes have been accomplished <i style="mso-bidi-font-style: normal">via two-component one pot condensation between substituted aldehydes and indoles using aqueous tamarind fruit juice as a natural catalysts. The use of water as reaction medium makes this process totally nonpolluting having several advantages such as mild reaction conditions, simple work-up procedures and reduces environmental impact

A green synthesis of amino Schiff bases using mango water as a natural catalyst under hand grinding technique

522-526The application of edible fruit juice in organic synthesis has attracted the interest of chemists, particularly from the view of green chemistry. A series of amino Schiff bases have been prepared in good to excellent yield from the condensation of 1,2-diaminobenzenes with various aromatic aldehydes in presence of mango water as a natural acid catalyst under hand grinding technique. The reaction is green and economically viable. The product is purified by simple filtration followed by crystallisation with ethanol and drying processes

Facile formation of bis(3-indolyl)methylarenes by iodine-catalyzed reaction of indole with ⍺,⍺'-bis(arylmethylene)ketones and ⍺-substituted arylmethyleneketones in dry ethanol

2056-2059Bis(3-indolyl)methylarenes are obtained in good yield by reaction of indole with ⍺,⍺-bis(arylmethylene)ketones and ⍺-substituted arylmethyleneketones in dry ethanol using catalytic amount of molecular iodine at room temperature. A plausible mechanism for formation of these products has been suggested

Iodine-catalysed conjugate addition of indole with <img src='/image/spc_char/alpha.gif' border=0> -cinnamylideneketones: Formation of <img src='/image/spc_char/beta.gif' border=0>-(3-indolyl)-<img src='/image/spc_char/alpha.gif' border=0> ,<img src='/image/spc_char/beta.gif' border=0>-dihydro-<img src='/image/spc_char/alpha.gif' border=0> -cinnamylideneketones and bis(3- indolyl)methylbenzene

619-623-(3-Indolyl)- ,-dihydro- -cinnamylideneketones and bis(3-indolyl)methylbenzene have been obtained in moderate to good yield by conjugate addition of indole with -cinnamylidene­ketones under mild reaction condition in dry ethanol using iodine as catalyst. The structures of the products have been established from their spectral data

Facile Condensation of Aromatic Aldehydes with Chroman-4-ones and 1-Thiochroman-4-ones Catalysed by Amberlyst-15 under Microwave Irradiation Condition

Different aromatic aldehydes and cinnamaldehyde undergo cross-aldol condensation with chroman-4-ones and1-thiochroman-4-ones in the presence of amberlyst-15 under microwave irradiation in solvent free condition to afford rapidly the corresponding E-3-arylidene and E-3-cinnamylidene derivatives, respectively, in high yield. This process is simple, efficient and environmentally benign

Amberlyst-15 catalyzed acetylation of heteroaromatics with acetic anhydride under solvent free conditions

198-200Amberlyst-15 has been found to be an efficient reusable hetero­geneous catalyst for acetylation of indole, 2-methylindole and pyrrole with acetic anhydride under solvent free conditions

trans-2-Phenyl-4-thiophenoxy-3,4-dihydro-2H-1-benzothiopyran

Iodine-catalyzed cyclocondensation of cinnamaldehyde and thiophenol yields rapidly trans-2-phenyl-4-thiophenoxy-3,4-dihydro-2H-1-benzothiopyran in excellent yield with very high diastereoselectivity