Modelo econometrico sectorial de la economia portuguesa e impacto positivo del comercio exterior

Se analiza la evolucion de la economia portuguesa en el periodo 1946-99, distinguiendo las etapas de apertura exterior de las etapas de autarquia, y evaluando el importante papel dinamizador de la apertura comercial al exterior para la economia portuguesa. Se estima un modelo macroeconometrico para el periodo 1951-92 que pone de manifiesto la importancia de las relaciones intersectoriales y el impacto positivo del comercio exterior sobre el desarrollo industrial y el crecimiento economico This article presents an analysis of the evolution of the Portuguese economy for the period 1950-99, with an special reference to the stages of openness to foreign trade and its positive impact on economic growth. A macroeconometric model is estimated for the period 1951-92, having into account intersectoral relations and the positive impact of external trade on industry and economic development.

Shape theory and mathematical design of a general geometric kernel through regular stratified objects

This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This dissertation focuses on the mathematical design of a unified shape kernel for geometric computing, with possible applications to computer aided design (CAM) and manufacturing (CAM), solid geometric modelling, free-form modelling of curves and surfaces, feature-based modelling, finite element meshing, computer animation, etc. The generality of such a unified shape kernel grounds on a shape theory for objects in some Euclidean space. Shape does not mean herein only geometry as usual in geometric modelling, but has been extended to other contexts, e. g. topology, homotopy, convexity theory, etc. This shape theory has enabled to make a shape analysis of the current geometric kernels. Significant deficiencies have been then identified in how these geometric kernels represent shapes from different applications. This thesis concludes that it is possible to construct a general shape kernel capable of representing and manipulating general specifications of shape for objects even in higher-dimensional Euclidean spaces, regardless whether such objects are implicitly or parametrically defined, they have ‘incomplete boundaries’ or not, they are structured with more or less detail or subcomplexes, which design sequence has been followed in a modelling session, etc. For this end, the basic constituents of such a general geometric kernel, say a combinatorial data structure and respective Euler operators for n-dimensional regular stratified objects, have been introduced and discussed

Evolucion de la Economia Portuguesa, 1946-2000: crecimiento, salarios y empleo

This article presents an analysis of the evolution of the Portuguese economy during the second half of the 20th century, having into account the stages of its evolution, and a comparison with Ireland, Spain and other European countries. We stand out the positive impact of human capital and EU membership for industrial development and external trade of Portugal. We present some econometric models to analyse the evolution of real value-added and employment in non-agrarian sectors during the periods 1990-99 and 1960-2000. In spite of the positive trends it is outstanding that the Portuguese economy needs to foster human capital and industrial development in order to increase real wages and income per inhabitant, following the model of the Irish economy.

La evaluación del lenguaje: incidencia evolutiva en el género y en el medio

[ES] En este estudio nos proponemos señalar la importancia de la comunicación oral en la infancia, analizar la adquisición de la competencia comunicativa y lingüística de los niños. Asimismo describir las principales alteraciónes en la adquisición, desarrollo y organización del lenguaje, para ello hicimos un análisis y revisión de las técnicas de evaluación del lenguaje infantil. Hemos elegido una prueba, la Prueba de Lenguaje Oral de Navarra – Revisada (PLON-R) y procedimos a su adaptación y baremación en la población portuguesa, con una muestra de 504 niños, según criterios de edades, género y entorno social (Rural/Urbano). Nos planteamos dos objetivos, el primero detectar mediante una técnica de evaluación las principales dificultades en el desarrollo del lenguaje y el nivel que el niño pueda manifestar en su expresión lingüística. La segunda, adecuar los resultados a un sistema informático para obtener la adecuada información sobre la necesidad, o no, de mejorar su expresión lingüística. Nuestra investigación ha planteado tres hipótesis. Una de incidencia evolutiva en la prontitud de adquisición del lenguaje en los niños de tres años de edad. La segunda hipótesis planteamos la diferencia evolutiva entre niños y niñas (3,4, 5 y 6 años de edad) en la adquisición de su expresión lingüística. La tercera hipótesis ha tenido en cuenta el ámbito de procedencia de los niños (Medio Rural/Urbano) y analizar posibles diferencias

TRIM25 targets p300 for degradation

p300 is an important transcriptional co-factor. By stimulating the transfer of acetyl residues onto histones and several key transcription factors, p300 enhances transcriptional initiation and impacts cellular processes including cell proliferation and cell division. Despite its importance for cellular homeostasis, its regulation is poorly understood. We show that TRIM25, a member of the TRIM protein family, targets p300 for proteasomal degradation. However, despite TRIM25’s RING domain and E3 activity, degradation of p300 by TRIM25 is independent of TRIM25-mediated p300 ubiquitination. Instead, TRIM25 promotes the interaction of p300 with dynein, which ensures a microtubule-dependent transport of p300 to cellular proteasomes. Through mediating p300 degradation, TRIM25 affects p300-dependent gene expression

Protein intake and obesity in schoolchildren

[resumo]Resumo de comunicação apresentada em: 16th European Congress on Obesity - ECO 2008; 2008 Mai 14-17; Genebra, Suíça

A Rodential Reckoning: A Case Report and Systematic Review of Streptobacillary Endocarditis

Introduction: Endocarditis is a rare, often fatal complication of rat bite fever caused by Streptobacillus moniliformis. Only 39 cases have been reported (including this case) as of 2022. We describe a case and aim to perform this entity’s first systematic literature review. Methods: We performed a systematic review in CENTRAL, EMBASE, MEDLINE, SciELO, and LILACS. The terms used were terms used were (but not limited to) rat bite fever, Streptobacillus moniliformis, Spirillum minus, and endocarditis. We included all abstracts and articles with patients with echocardiographic or histologicproven endocarditis. In case of discordance, a third reviewer was involved. Our protocol was submitted to PROSPERO (CRD42022334092). We also performed searches for studies on the reference list of included articles. Results: We retrieved 108 and included 36 abstracts and articles. A total of 39 patients (including our report) were identified. The mean age was 41.27, and 61.5% were males. The most common findings were fever, murmur, arthralgias, fatigue, splenomegaly, and rash. Underlying heart disease was present in 33%. Exposure to rats was noted in 71.8% of patients, with 56.4% recalling a rat bite. Anemia was seen in 57%, leukocytosis in 52%, and elevated inflammatory markers in 58% that had lab work performed. The mitral valve was most affected, followed by the aortic, tricuspid, and pulmonary valves. Surgical intervention was required in 14 (36%) cases. Of those, 10 required valve replacement. Death was reported in 36% of cases. Unfortunately, the literature available is limited to case series and reports. Conclusion: Our review allows clinicians to suspect better, diagnose, and manage Streptobacillary endocarditis

Sodium and potassium urinary excretion and dietary intake: a cross-sectional analysis in adolescents

Background: Hypertension is the leading cause for heart disease and stroke, for mortality and morbidity worldwide, and a high sodium-to-potassium intake ratio is considered a stronger risk factor for hypertension than sodium alone. Objective: This study aims to evaluate sodium and potassium urinary excretion, and assess the food sources of these nutrients in a sample of Portuguese adolescents. Design: A cross-sectional study with a sample of 250 Portuguese adolescents. Sodium and potassium excretion were measured by one 24-h urinary collection, and the coefficient of creatinine was used to validate completeness of urine collections. Dietary sources of sodium and potassium were assessed using a 24-h dietary recall. Results: Valid urine collections were provided by 200 adolescents (118 girls) with a median age of 14.0 in both sexes (p 0.295). Regarding sodium, the mean urinary excretion was 3,725 mg/day in boys and 3,062 mg/day in girls (pB0.01), and 9.8% of boys and 22% of girls met the World Health Organization (WHO) recommendations for sodium intake. Concerning potassium, the mean urinary excretion was 2,237 mg/day in boys and 1,904 mg/day in girls (pB0.01), and 6.1% of boys and 1.7% of girls met theWHOrecommendations for potassium intake. Major dietary sources for sodium intake were cereal and cereal products (41%), meat products (16%), and milk and milk products (11%); and for potassium intake, main sources were milk and milk products (21%), meat products (17%), and vegetables (15%). Conclusions: Adolescents had a high-sodium and low-potassium diet, well above the WHO recommendations. Health promotion interventions are needed in order to decrease sodium and increase potassium intake

Body mass index categories and attained height in Portuguese adults

Objective: To analyze the associations between height and BMI categories in a Portuguese representative sample. Methods: This is a cross-sectional study with a representative sample of 32,644 Portuguese adults (52.4% females). Sociodemographic and lifestyle characteristics were obtained along with self-reported height and weight. We performed generalized linear models to assess the differences in attained height across BMI categories; analyses were adjusted for age, gender, education, family income per month, proxy reporting information, dietary patterns, and smoking. Results: BMI categories included underweight and normal weight (46.4%), overweight (37.6%), obese class I and II (15.2%), and obese class III (0.8%). Adults with normal weight had a significantly higher height (females +7 cm and males +5 cm) when compared to obese class III. As BMI categories increased, height decreased. In females and males, after adjusting for confounders, estimates of attained height decreased when compared to the unadjusted model (beta = -0.049, 95% CI = -0.050; -0.049 and beta = -0.030, 95% CI = -0.031; -0.029, respectively), although they remained still significant. Conclusion: Our results suggest a significant difference in attained height between BMI categories. Future intervention programs aiming at preventing overweight and obesity should monitor sociodemographic, health and environmental conditions that affect attained height potential.- (undefined

Results of a school-based asthma assessment from the upKids questionnaire validation study

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