13 research outputs found

    Evaluation of Formation Damage and Assessment of Well Productivity of Oredo Field, Edo State, Nigeria

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    Formation damage canincurconsiderable cost for remediation and deferred production. Thorough understanding of the formation damage mechanisms, stringent measures for its control and prevention, and effective and efficient treatments are the keys for optimum production strategies for oil and gas fields. WELL 4X was investigated in this study to properly diagnosed and evaluate productivity in OREDO FIELD and Bottom Hole Pressure survey was used from Bottom Hole Pressure analysis in addition to the information of the well production history and reservoir data available to determine and assess the extent of the formation damage in the well. The WELL 4X was stimulated using Acid Foam Diversion Techniques to enhance reservoir productivity and increase economic operations. The stimulation job done on the well showed a peak increase of production from 850 bbl/day to 3200 b/d before it declined to 2150 bbl/day, and finally maintained an average stabilized rate of 2000 bbl/day. It has to be established that the treatment method on WELL 4X using Acid Foam Diversion Techniques and the Bottom Hole Pressure survey conducted on the WELL 4X in OREDO FIELD is found to be efficient in the determination and evaluation of formation damage

    Pharyngeal carriage of Neisseria species in the African meningitis belt.

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    OBJECTIVES: Neisseria meningitidis, together with the non-pathogenic Neisseria species (NPNs), are members of the complex microbiota of the human pharynx. This paper investigates the influence of NPNs on the epidemiology of meningococcal infection. METHODS: Neisseria isolates were collected during 18 surveys conducted in six countries in the African meningitis belt between 2010 and 2012 and characterized at the rplF locus to determine species and at the variable region of the fetA antigen gene. Prevalence and risk factors for carriage were analyzed. RESULTS: A total of 4694 isolates of Neisseria were obtained from 46,034 pharyngeal swabs, a carriage prevalence of 10.2% (95% CI, 9.8-10.5). Five Neisseria species were identified, the most prevalent NPN being Neisseria lactamica. Six hundred and thirty-six combinations of rplF/fetA_VR alleles were identified, each defined as a Neisseria strain type. There was an inverse relationship between carriage of N. meningitidis and of NPNs by age group, gender and season, whereas carriage of both N. meningitidis and NPNs was negatively associated with a recent history of meningococcal vaccination. CONCLUSION: Variations in the prevalence of NPNs by time, place and genetic type may contribute to the particular epidemiology of meningococcal disease in the African meningitis belt

    Pharyngeal carriage of Neisseria species in the African meningitis belt.

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    OBJECTIVES: Neisseria meningitidis, together with the non-pathogenic Neisseria species (NPNs), are members of the complex microbiota of the human pharynx. This paper investigates the influence of NPNs on the epidemiology of meningococcal infection. METHODS: Neisseria isolates were collected during 18 surveys conducted in six countries in the African meningitis belt between 2010 and 2012 and characterized at the rplF locus to determine species and at the variable region of the fetA antigen gene. Prevalence and risk factors for carriage were analyzed. RESULTS: A total of 4694 isolates of Neisseria were obtained from 46,034 pharyngeal swabs, a carriage prevalence of 10.2% (95% CI, 9.8-10.5). Five Neisseria species were identified, the most prevalent NPN being Neisseria lactamica. Six hundred and thirty-six combinations of rplF/fetA_VR alleles were identified, each defined as a Neisseria strain type. There was an inverse relationship between carriage of N. meningitidis and of NPNs by age group, gender and season, whereas carriage of both N. meningitidis and NPNs was negatively associated with a recent history of meningococcal vaccination. CONCLUSION: Variations in the prevalence of NPNs by time, place and genetic type may contribute to the particular epidemiology of meningococcal disease in the African meningitis belt.MenAfriCar was funded by the Wellcome Trust (086546/Z/08/Z) and the Bill and Melinda Gates Foundation (51251). Kanny Diallo holds a Wellcome Trust Training Fellowship in Public Health and Tropical Medicine.This is the final version of the article. It first appeared from Elsevier via https://doi.org/10.1016/j.jinf.2016.03.01

    Conflicts over farmland and its socioeconomic effects on rural residents of Southwestern Nigeria

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    Land is increasingly becoming a source of conflicts in Nigeria and Africa at large where land access had traditionally been characterised as relatively unrestricted. This paper examined conflicts over farmland and its socio economic effects on the rural residents of southwestern Nigeria. Multi-stage sampling technique was used to select 160 respondents for the study. Data were collected through a structured questionnaire and analysed using descriptive statistics. Findings revealed that the major causes of conflict over farmland in the area were failure to respect boundary (x 1.66± 0.58), contesting for the inheritance of land boundary (x 1.65±0.65) and abandonment of the previously accepted rules of access to and use of land (x 1.09± 0.63). Farmland conflicts terminates the social interaction and peaceful co-existence of people (x 1.65±0.48), causing mistrust among members (x 1.61±0.49), destruction of goods and property (x 1.57± 0.50) and loss of life (x 1.55±0.57). It was concluded based on the findings that conflict over farmland had negative effects on the socio-economic activities of the rural residents. Consequently, the study recommends that individual and community farm boundaries must be respected.There must be an effective system of land administration of management to reduce frequent challenges of land ownership. Inheritors should be loyal to the agreement made with their progenitors on the use of land and public education/enlightenment programmes must be strengthening to reduce the adverse effect of conflicts over farmland

    Use of endogenous knowledge in treating pests and diseases of small ruminants in Obokun government area of Osun State

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    This paper examined the use of endogenous knowledge in treating pests and diseases of goats and sheep in Obokun Local Government Area of Osun State. Multi stage sampling technique was used to select one hundred and twenty rearers of small ruminants in the study area. Data were collected through a structured interview schedule and analysed using frequency counts and chi-square. Majority (88.3%) of the respondents were female, while 60.0% had one form of education or the other. The mean age was 50.7±16.5years. The most used method in treating pests of small ruminants were adding shea butter oil and salt in treating mange̅ 1.23 ± 0.67 , hand picking of tick ̅ 1.08 ± 0.76 and rubbing the body of animal with palm kernel oil and salt for lice 0.45 ± 0.77 , while those of diseases include treating helminthiasis with lime orange and grinded pawpaw seed ̅ 1.51 ± 0.63 , using solution of charcoal and bitter leaf for diarrhoea̅ 1.30 ± 0.64 , and treating catarrh with tobacco snuff and pepper ̅ 1.26 ± 0.63 . Larger proportion (71.7%) of the respondents were categorized as high level users of endogenous methods. Educational level, marital status and sex do not significantly affect the level of use of endogenous knowledge. Endogenous knowledge is still relevant in managing common pest and diseases of small ruminants in the rural areas. It is therefore recommended that the knowledge be documented and incorporated in preventive and curative medicine for ease of passage from generation to generation so as to prevent it from extinction

    Nutritional rickets in young Nigerian children in the Sahel Savanna

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    (East African Medical Journal 2001: 78 (11): 568-575

    Methods for identifying Neisseria meningitidis carriers: a multi-center study in the African meningitis belt.

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    OBJECTIVE: Detection of meningococcal carriers is key to understanding the epidemiology of Neisseria meningitidis, yet no gold standard has been established. Here, we directly compare two methods for collecting pharyngeal swabs to identify meningococcal carriers. METHODS: We conducted cross-sectional surveys of schoolchildren at multiple sites in Africa to compare swabbing the posterior pharynx behind the uvula (U) to swabbing the posterior pharynx behind the uvula plus one tonsil (T). Swabs were cultured immediately and analyzed using molecular methods. RESULTS: One thousand and six paired swab samples collected from schoolchildren in four countries were analyzed. Prevalence of meningococcal carriage was 6.9% (95% CI: 5.4-8.6%) based on the results from both swabs, but the observed prevalence was lower based on one swab type alone. Prevalence based on the T swab or the U swab alone was similar (5.2% (95% CI: 3.8-6.7%) versus 4.9% (95% CI: 3.6-6.4%) respectively (p=0.6)). The concordance between the two methods was 96.3% and the kappa was 0.61 (95% CI: 0.50-0.73), indicating good agreement. CONCLUSIONS: These two commonly used methods for collecting pharyngeal swabs provide consistent estimates of the prevalence of carriage, but both methods misclassified carriers to some degree, leading to underestimates of the prevalence

    The diversity of meningococcal carriage across the african meningitis belt and the impact of vaccination with a group a meningococcal conjugate vaccine

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    Background. Study of meningococcal carriage is essential to understanding the epidemiology of Neisseria meningitidis infection. Methods. Twenty cross-sectional carriage surveys were conducted in 7 countries in the African meningitis belt; 5 surveys were conducted after introduction of a new serogroup A meningococcal conjugate vaccine (MenAfriVac). Pharyngeal swab specimens were collected, and Neisseria species were identified by microbiological and molecular techniques. Results. A total of 1687 of 48 490 participants (3.4%; 95% confidence interval [CI], 3.2%-3.6%) carried meningococci. Carriage was more frequent in individuals aged 5-14 years, relative to those aged 15-29 years (adjusted odds ratio [OR], 1.41; 95% CI, 1.25-1.60); in males, relative to females (adjusted OR, 1.17; 95% CI, 1.10-1.24); in individuals in rural areas, relative to those in urban areas (adjusted OR, 1.44; 95% CI, 1.28-1.63); and in the dry season, relative to the rainy season (adjusted OR, 1.54; 95% CI, 1.37-1.75). Forty-eight percent of isolates had genes encoding disease-associated polysaccharide capsules; genogroup W predominated, and genogroup A was rare. Strain diversity was lower in countries in the center of the meningitis belt than in Senegal or Ethiopia. The prevalence of genogroup A fell from 0.7% to 0.02% in Chad following mass vaccination with MenAfriVac. Conclusions. The prevalence of meningococcal carriage in the African meningitis belt is lower than in industrialized countries and is very diverse and dynamic, even in the absence of vaccination
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