Pengaruh Elisitor Biotik Dan Abiotik Pada Produksi Flavonoid Melalui Kultur Jaringan Tanaman

Plant tissue culture appears to be a good alternative for production of bioactive secondary metabolites, such as flavonoids. These metabolites are naturally phenolic compounds in fruits, vegetables, seeds, bark, roots, stems, and flowers with various biological activities. Application of this method can increase secondary metabolites productivity through changes in expression of metabolic pathways, mainly by biotic and abiotic elicitors utilization. Elicitors influence secondary metabolites production through secondary pathway activation as a major response to biotic and abiotic stresses. Many studies have been being performed to find elicitors with an outstanding influence on the accumulation of flavonoids and its mechanisms. Key words: plant tissue culture, flavonoids, biotic elicitors, abiotic elicitors

Pencarian Tumbuhan Obat yang Berpotensi sebagai Antimalaria Berdasarkan Pengetahuan Etnomedisin

Malaria merupakan suatu penyakit yang disebabkan oleh beberapa parasit Plasmodium dan menjadi salah satu penyakit infeksi utama di beberapa daerah tropis seperti negara-negara Asia dan Afrika. Masalah utama dalam mengatasi malaria adalah adanya peningkatan resistensi vektor terhadap insektisida dan peningkatan resistensi parasit terhadap obat malaria, seperti klorokuin dan artemisinin. Masyarakat, khususnya para pengobat tradisional di berbagai daerah endemik tersebut telah menggunakan tumbuhan sebagai pengobatan turun-temurun untuk mengatasi demam dan gejala malaria lainnya. Fakta ini mendorong para peneliti untuk menemukan agen antimalaria baru yang terjangkau, mudah diperoleh, dan diterima secara budaya berdasarkan pengetahuan etnomedisin

Studi Etnofarmasi Penggunaan Tumbuhan Obat Oleh Suku Tengger Di Kabupaten Lumajang Dan Malang, Jawa Timur

Tengger is one of tribes in Indonesia which still conserves its tradition and culture, including local knowledge about medicinal plants remedy. Their people live in Probolinggo, Pasuruan, Lumajang, and Malang dictrict, East Java. Among the four districts, Tengger tribe in Lumajang and Malang get more influenced than the others because of Islam integration and their far location from the center of Tengger cultural rituals. Currently, young generation of Tengger tribe tend to choose conventional medicine because of their fast action and practicality. To avoid the extinction of this culture, it is need to find more information about their traditional remedy. One of methods used to explore local knowledge of medicinal plants is ethnopharmacy. Key words: ethnopharmacy, Tengger tribe, medicinal plants

Peran Studi Etnofarmasi Dalam Pencarian Tumbuhan Obat Yang Berpotensi Dikembangkan Sebagai Antidiabetes

The prevalence of diabetes mellitus has been increasing worldwide and it becomes one of the main diseases which affect human health. Many clinicians prescribe polytheraphy with two or more hypoglycemic agents to achieve better glucose control as a common practice. Patients also have to take drugs for long-term therapy with their attendant side effects in addition to their high costs. It may increase non-adherence therapy of diabetic patients. As a result, patients choose alternative treatment by using herbal medicines. To search new antidiabetic medicinal plants, we can use ethnopharmacy study as an option. This approach has been used to search locally important plant species to control diabetes mellitus in traditional medicinal systems of different cultures. Key words: ethnopharmacy, diabetes mellitus, medicinal plants

DINAMIKA COPING STRESS WANITA DEWASA AWAL YANG MENGALAMI ENDOMETRIOSIS

When a woman is a teenager, she will experience menstrual periods. Menstrual pain is normal for a woman. If the woman continues to experience more pain than usual, this is one of the symptoms of endometriosis. The pain that arises makes a person experience stress due to the disease itself. To deal with stress, it is necessary to carry out a resistance strategy, namely a stress coping strategy. The aim of the researchers was to determine the dynamics of stress coping in early adult women with endometriosis. This study uses an inductive qualitative approach with phenomenological methods. The informants in this study were individuals diagnosed with endometriosis. Data collection in this study was carried out through an interview process with two research informants. The results of this study indicate that when the two informants were diagnosed with endometriosis, the impact felt by the two informants was feeling stressed, anxious and afraid of the pain they experienced. To deal with the stress experienced by the two informants, they came up with coping strategies. In the form of focus coping problem, the two informants dealt with pain by taking medication, compressing the stomach with warm water, changing diet and lifestyle. In addition, emotional focus coping treatment by diverting to other things such as self-suggestions

ANALYSIS OF FINANCIAL PERFORMANCE BEFORE AND DURING THE COVID-19 PANDEMIC

This study aims to find out how the differences in the financial performance of the Healthcare sector companies listed on the Indonesia Stock Exchange before and after the entry of covid-19 in Indonesia. The financial performance includes net profit margin, current ratio, debt to equity ratio, and total asset turn over. The type of research used is quantitative. The population used is healthcare companies listed on the Indonesia Stock Exchange in 2017-2020 with a purposive sampling technique so that 40 data are obtained. The data analysis technique used is descriptive data analysis technique, paired sample test and Wilcoxon. The results of this study indicate that the net profit margin, debt to equity ratio, and total asset turnover have no difference before and when Covid-19 entered Indonesia. Meanwhile, the current ratio has a difference between before and when Covid-19 entered Indonesia

PERAWATAN TUBUH CALON PENGANTIN DENGAN RAMUAN TRADISIONAL MADURA SEBELUM HARI PERNIKAHAN DI RUMAH SPA KERATON SUMENEP

Abstrak Ramuan tradisional merupakan ciri khas dan kearifan lokal yang dimiliki setiap daerah. Di Madura ramuan tradisional dibuat untuk bahan perawatan tubuh calon pengantin wanita. Penelitian ini dilakukan untuk mengetahui (1) Macam-macam perawatan tubuh calon pengantin dengan ramuan tradisional Madura di rumah SPA Keraton Sumenep (2) khasiat ramuan tradisonal Madura bagi calon pengantin sebelum hari pernikahan. Jenis penelitian ini adalah penelitian deskriptif dengan metode pendekatan kualitatif menggunakan metode pengumpulan data wawancara, observasi dan dokumentasi. Metode analisis data yang digunakan dalam penelitian ini adalah metode analisis kualitatif. Teknik analisis data menggunakan reduksi data. Hasil penelitian perawatan tubuh calon pengantin adalah 1) Perawatan tubuh dari luar meliputi perawatan massage, lulur, masker, ratus, cem-ceman. Perawatan tubuh dari dalam dengan mengkonsumsi jamu paka’ dan jamu godog. Ramuan yang digunakan dalam melakukan perawatan tubuh bagi calon pengantin terbuat dari rempah-rempah, kunyit, melati, kayu manis, jeruk purut dan cengkeh (2) Khasiat ramuan tradisional Madura bagi calon pengantin wanita di Rumah SPA Keraton Sumenep adalah merawat kecantikan tubuh dan menjaga kesehatan organ intim menjelang hari pernikahan. Kata Kunci: Perawatan tubuh, Ramuan tradisional Madura, Rumah Spa Keraton Sumenep Abstract Traditional ingredients are characteristic and local wisdom of each region. In Madura traditional concoctions are made for the grooms body care ingredients. This research was conducted to determine (1) Types of body treatments for the bride and groom with traditional Madura ingredients at the Sumenep Keraton SPA home (2) the efficacy of traditional Madura herbs for the bride and groom before the wedding day. This type of research is a descriptive study with a qualitative approach using interview, observation and documentation data collection methods. The data analysis method used in this study is a qualitative analysis method. Data analysis techniques using data reduction. The results of research on the body care of the bride and groom are 1) Body treatments from outside include massage treatments, scrubs, masks, hundred, cem-ceman. Body care from the inside by consuming herbal medicine ’and godog herbal medicine. The ingredients used in body care for the bride and groom are made from spices, turmeric, jasmine, cinnamon, kaffir lime and cloves. sex organs before the wedding day. Keywords: Body care, Madura traditional ingredients, Keraton Sumenep Spa Hous

Aktivitas Penyembuhan Luka Infeksi Krim Kombinasi Daun Sirsak (Annona muricata L.) Dan Daun Sirih (Piper betle L.) Dengan Bakteri Staphylococcus aureus Pada Punggung Kelinci New Zealand White Secara In Vivo

Several types of tropical plants in Indonesia that contain anti-bacterial chemical compounds such as tannins, flavonoids and saponins, namely betel (Piper betle L.) leaves and soursop (Annona muricata L.) leaves. Objectives of the research was to determine activity of cream from soursop (Annona muricata L.) leaves ethanol extract and betel (Piper betle L.) leaves ethanol extract on the backs of rabbits infected with Staphylococcus aureus bacteria. In addition, the research conducted could also determine the stability of cream that produced and its pharmacological effects. Data analysis technique using ANOVA method, significance value did not reach 0.05. Extraction process using 70% ethanol as solvent with extraction method, namely maceration. Parameters of cream preparation were from level of storage duration for 0 days and concentration used. Then the level of cream preparation effectiveness in wounds healing could be seen from observations of wounds and pus drying time as well as edema and erythema loss. Cream preparation from combination of soursop (Annona muricata L.) leaves ethanol extract and betel (Piper betle L.) ethanol extract in formula 6 with concentration ratio of 10%: 12.5%, resulted better and faster healing rate against Staphylococcus aureus infection than other formulas. Required recovery time interval was 10 days and cream preparation had good stability

Aloe Vera: Potential to Reduce Fasting Blood Sugar Levels in Prediabetes

Prediabetes is a continuous spectrum of developmental stages before a person is diagnosed with diabetes mellitus. Considering the long-term effects of pharmacological treatment, other natural-based methods are needed. The purpose of this study was to analyze the effect of Aloe Vera Juice on the reduction of fasting blood glucose levels in patients with prediabetes in Pontianak City. A pre and post-test design study was conducted between March and July 2021 at Alianyang Public Health Center. A total of 12 subjects were identified as prediabetic at the beginning of the study through screening involved in this study. The included subjects were asked to consume 175 ml of Aloe Vera Juice for 15 consecutive days and measured their fasting blood glucose (FBG) levels on the 16th day. A paired t-test was performed to determine the difference in FBG levels before and after the treatment. Present findings revealed that the mean FBG level before intervention was 107.4 mg / dL and 92.1 mg/dL after the intervention. A statistically different FBG reduction significance was found between groups (p<0.001). Consuming Aloe vera juice regularly for 15 days has proven to lower FBG levels among prediabetics. Future studies with better adherence monitor and larger sample sizes might have resulted in better determination of the intervention's effect.