Digital Envelope System Based on Optimized NTRU (Number Theory Research Unit) and RC6 Algorithm

With the rapid development of technologies, more data are generated and transmitted in the medical, commercial, and military fields, which may include some sensitive information. So, security is essential to transfer the important information securely over the communication channels. To fulfill the information security requirements, many security systems were proposed in many research areas. On the other hand, many cryptographic algorithms are analyzed and optimized to evaluate better performance according to their requirements. This work proposes digital envelope system in order to meet the security requirement such as confidentiality. To create digital envelope system, the original message is encrypted by using Rivest Cipher-6(RC6) with the help of secret key. Then, that secret key is encrypted by using the ONTRU (Optimized Number Theory Research Unit) with the help of Receiver’s public key.  Moreover, this work also focuses on the optimization of NTRU to obtain better execution time for the digital envelope system. According to the analytical results, it is found that ONTRU is faster than NTRU. The basic idea behind this paper is to provide a good, faster digital envelope system

Detection of East/Central/South African Genotype of Chikungunya Virus in Myanmar, 2010

In 2010, chikungunya virus of the East Central South African genotype was isolated from 4 children in Myanmyar who had dengue-like symptoms. Phylogenetic analysis of the E1 gene revealed that the isolates were closely related to isolates from China, Thailand, and Malaysia that harbor the A226V mutation in this gene

2015年にミャンマー国で発生したデング熱流行の臨床、ウイルス学、疫学解析

Hospital-based surveillance was conducted at two widely separated regions in Myanmar during the 2015 dengue epidemic. Acute phase serum samples were collected from 332 clinically diagnosed dengue patients during the peak season of dengue cases. Viremia levels were measured by quantitative real-time PCR and plaque assays using FcγRIIA-expressing and non-FcγRIIA-expressing BHK cells to specifically determine the infectious virus particles. By serology and molecular techniques, 280/332 (84・3%) were confirmed as dengue patients. All four serotypes of dengue virus (DENV) were isolated from among 104 laboratory-confirmed patients including two cases infected with two DENV serotypes. High percentage of primary infection was noted among the severe dengue patients. Patients with primary infection or DENV IgM negative demonstrated significantly higher viral loads but there was no significant difference among the severity groups. Viremia levels among dengue patients were notably high for a long period which was assumed to support the spread of the virus by the mosquito vector during epidemic. Phylogenetic analyses of the envelope gene of the epidemic strains revealed close similarity with the strains previously isolated in Myanmar and neighboring countries. DENV-1 dominated the epidemic in 2015 and the serotype (except DENV-3) and genotype distributions were similar in both study sites.長崎大学学位論文 学位記番号:博(医歯薬)甲第984号 学位授与年月日:平成29年9月20日Author: A. K. KYAW, M. M. NGWE TUN, M. L. MOI, T. NABESHIMA, K. T. SOE, S. M. THWE, A. A. MYINT, K. T. T. MAUNG, W. AUNG, D. HAYASAKA, C. C. BUERANO, K. Z. THANT and K. MORITACitation: Epidemiology & Infection, 145(9), pp.1886-1897; 2017Nagasaki University (長崎大学)課程博

Febrile illness in Asia: gaps in epidemiology, diagnosis and management for informing health policy

There is increasing evidence on the aetiology and management of fevers in Asia, the importance of which has risen with declines in malaria incidence.To conduct a narrative review of the epidemiology and management of fevers in South and South-East Asia and to highlight gaps in our knowledge that impair evidence-based health policy decisions.A narrative review of papers published since 2012 of developments in fever epidemiology, diagnosis and treatment in South and South-East Asia. The papers that the authors felt were pivotal, from their personal perspectives, are discussed.We identified 100 studies. Among thirty studies (30%) including both children and adults that investigated three or more pathogens, dengue was reported the most frequently, by 15 (50%), followed by leptospirosis by 8 (27%), scrub typhus by 7 (23%) and Salmonella Typhi by 6 (20%). Among four studies investigating three or more pathogens in children, dengue and Staphylococcus aureus were the most frequent, followed by non-typhoidal Salmonella spp., Streptococcus pneumoniae, Salmomella Typhi, and scrub typhus. Increased awareness that rickettsial pathogens are common but will not respond to cephalosporins and that alternatives, such as tetracyclines, are required is needed.Many key gaps remain and consensus guidelines for study design are needed to aid comparative understanding of the epidemiology of fevers. More investment in developing accurate and affordable diagnostic tests for rural Asia and independent evaluation of those on the market are needed. Treatment algorithms, including simple biomarker assays, appropriate for empirical therapy of fevers in different areas of rural Asia should be a major aim of fever research. Enhanced antimicrobial resistance (AMR) surveillance and openly accessible databases of geography-specific AMR data would inform empirical and specific therapy policy. More investment in innovative strategies facilitating infectious disease surveillance in remote rural communities would be an important component of poverty reduction and improving public health