172 research outputs found
Federal mandates and mortgage supply : regression discontinuity analyses of the community reinvestment and GSE Acts.
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Economics, 2008.Includes bibliographical references.In this dissertation, I provide evidence of the causal impact on mortgage supply of the Community Reinvestment Act (CRA) and the "Government-Sponsored Enterprises (GSE) Act", laws requiring banks and the GSEs (Fannie Mae and Freddie Mac), respectively, to help improve credit access for low-income households and neighborhoods. While financial markets evolved rapidly since the early 1990's, I use discontinuities in the laws' eligibility rules to identify their effects. To implement the analyses, I use a census of mortgage applications collected under the Home Mortgage Disclosure Act. Overall, these programs appear to have had limited impact. I first analyze CRA's effect on mortgage lending in targeted neighborhoods: census tracts with a median family income (MFI) under 80% of MSA MFI. The regression discontinuity (RD) estimates suggest an overall credit supply shift of at least 2007) from 1994 and 2002 in targeted neighborhoods. In addition to CRA's direct effect on bank lending, I also find that unregulated institutions lend more in targeted tracts ("crowd-in"). Further analysis suggests that information spillovers from increased bank lending helps generate crowd-in. In Chapter 2, I examine CRA's effect on home purchase mortgage lending to households with income under 80% of the MSA MFI. In both Chapters 1 and 2, I find CRA's impact is concentrated in the largest MSAs, where enforcement is most intense. The RD estimates indicate that CRA caused a 6% increase in large MSA bank home purchase lending at the cutoff.(cont.) Unlike in Chapter 1, there is no theoretical basis for crowd-in and none is found. Nor do I find that banks crowd-out unregulated institutions. Finally, I measure the impact of one of the three goals established under the GSE Act. Under this goal the GSEs target census tracts with MFI under 90% of MSA MFI. The RD estimates suggest this goal led to a 3-4% increase in GSE purchases, and increased GSE-eligible originations by 2-3% at the cutoff. Unlike previous research, I find no evidence that the GSEs crowd-out FHA and subprime loans. The results imply a lower bound of the goal's impact of $2.4 billion between 1997 and 2002.Ph.D
The 2009 HMDA data: the mortgage market in a time of low interest rates and economic distress
Mortgages ; Home Mortgage Disclosure Act
The 2008 HMDA data: the mortgage market during a turbulent year
The data that mortgage lending institutions reported for 2008 under the Home Mortgage Disclosure Act of 1975 (HMDA) reflect the ongoing difficulties in the housing and mortgage markets. This article presents a number of key findings from a review of the 2008 HMDA data. In particular, it documents a reduction in lending activity that was experienced by all groups of borrowers, highlights the Federal Housing Administration's greatly expanded role in the mortgage market, and examines how atypical changes in the interest rate environment affected the incidence of reported higher-priced lending in 2008 relative to earlier years.Mortgages ; Home Mortgage Disclosure Act
Eustachian tube dysfunction: A diagnostic accuracy study and proposed diagnostic pathway.
BACKGROUND AND AIMS: Eustachian tube dysfunction (ETD) is a commonly diagnosed disorder of Eustachian tube opening and closure, which may be associated with severe symptoms and middle ear disease. Currently the diagnosis of obstructive and patulous forms of ETD is primarily based on non-specific symptoms or examination findings, rather than measurement of the underlying function of the Eustachian tube. This has proved problematic when selecting patients for treatment, and when designing trial inclusion criteria and outcomes. This study aims to determine the correlation and diagnostic value of various tests of ET opening and patient reported outcome measures (PROMs), in order to generate a recommended diagnostic pathway for ETD. METHODS: Index tests included two PROMs and 14 tests of ET opening (nine for obstructive, five for patulous ETD). In the absence of an accepted reference standard two methods were adopted to establish index test accuracy: expert panel diagnosis and latent class analysis. Index test results were assessed with Pearson correlation and principle component analysis, and test accuracy was determined. Logistic regression models assessed the predictive value of grouped test results. RESULTS: The expert panel diagnosis and PROMs results correlated with each other, but not with ET function measured by tests of ET opening. All index tests were found to be feasible in clinic, and acceptable to patients. PROMs had very poor specificity, and no diagnostic value. Combining the results of tests of ET function appeared beneficial. The latent class model suggested tympanometry, sonotubometry and tubomanometry have the best diagnostic performance for obstructive ETD, and these are included in a proposed diagnostic pathway. CONCLUSIONS: ETD should be diagnosed on the basis of clinical assessment and tests of ET opening, as PROMs have no diagnostic value. Currently diagnostic uncertainty exists for some patients who appear to have intermittent ETD clinically, but have negative index test results.M.S. received funding from the Cambridge Hearing Trus
Eustachian tube dysfunction: A diagnostic accuracy study and proposed diagnostic pathway
<div><p>Background and aims</p><p>Eustachian tube dysfunction (ETD) is a commonly diagnosed disorder of Eustachian tube opening and closure, which may be associated with severe symptoms and middle ear disease. Currently the diagnosis of obstructive and patulous forms of ETD is primarily based on non-specific symptoms or examination findings, rather than measurement of the underlying function of the Eustachian tube. This has proved problematic when selecting patients for treatment, and when designing trial inclusion criteria and outcomes. This study aims to determine the correlation and diagnostic value of various tests of ET opening and patient reported outcome measures (PROMs), in order to generate a recommended diagnostic pathway for ETD.</p><p>Methods</p><p>Index tests included two PROMs and 14 tests of ET opening (nine for obstructive, five for patulous ETD). In the absence of an accepted reference standard two methods were adopted to establish index test accuracy: expert panel diagnosis and latent class analysis. Index test results were assessed with Pearson correlation and principle component analysis, and test accuracy was determined. Logistic regression models assessed the predictive value of grouped test results.</p><p>Results</p><p>The expert panel diagnosis and PROMs results correlated with each other, but not with ET function measured by tests of ET opening. All index tests were found to be feasible in clinic, and acceptable to patients. PROMs had very poor specificity, and no diagnostic value. Combining the results of tests of ET function appeared beneficial. The latent class model suggested tympanometry, sonotubometry and tubomanometry have the best diagnostic performance for obstructive ETD, and these are included in a proposed diagnostic pathway.</p><p>Conclusions</p><p>ETD should be diagnosed on the basis of clinical assessment and tests of ET opening, as PROMs have no diagnostic value. Currently diagnostic uncertainty exists for some patients who appear to have intermittent ETD clinically, but have negative index test results.</p></div
The acceptability of three vaccine injections given to infants during a single clinic visit in South Africa
BACKGROUND: The Expanded Programme on Immunisation (EPI) has increased the number of antigens and injections
administered at one visit. There are concerns that more injections at a single immunisation visit could decrease
vaccination coverage. We assessed the acceptability and acceptance of three vaccine injections at a single immunisation
visit by caregivers and vaccinators in South Africa.
METHODS: A mixed methods exploratory study of caregivers and vaccinators at clinics in two provinces of South
Africa was conducted. Quantitative and qualitative data were collected using questionnaires as well as observations
of the administration of three-injection vaccination sessions.
RESULTS: The sample comprised 229 caregivers and 98 vaccinators. Caregivers were satisfied with the vaccinators’ care
(97 %) and their infants receiving immunisation injections (93 %). However, many caregivers, (86 %) also felt that
three or more injections were excessive at one visit. Caregivers had limited knowledge of actual vaccines provided,
and reasons for three injections. Although vaccinators recognised the importance of informing caregivers about
vaccination, they only did this sometimes. Overall, acceptance of three injections was high, with 97 % of caregivers
expressing willingness to bring their infant for three injections again in future visits despite concerns about the
pain and discomfort that the infant experienced. Many (55 %) vaccinators expressed concern about giving three
injections in one immunisation visit. However, in 122 (95 %) observed three-injection vaccination sessions, the
vaccinators administered all required vaccinations for that visit. The remaining seven vaccinations were not completed
because of vaccine stock-outs.
CONCLUSIONS: We found high acceptance by caregivers and vaccinators of three injections. Caregivers’ poor
understanding of reasons for three injections resulted from limited information sharing by vaccinators for caregivers.
Acceptability of three injections may be improved through enhanced vaccinator-caregiver communication, and
improved management of infants’ pain. Vaccinator training should include evidence-informed ways of communicating
with caregivers and reducing injection pain. Strategies to improve acceptance and acceptability of three injections
should be rigorously evaluated as part of EPI’s expansion in resource-limited countries.IS
A call for an immediate ceasefire and peaceful end to the Russian aggression against Ukraine
The Lancet–SIGHT Commission condemns the Russian Government's aggression against Ukraine and its attacks on civilians and civilian infrastructure, including health workers and hospitals. We support the March 2, 2022 UN General Assembly (UNGA) resolution ES-11/1 that “deplores in the strongest terms the aggression by the Russian Federation”. The indiscriminate use of weaponry violates international humanitarian law and has caused catastrophic health impacts, especially on children, older people, and disabled persons, and social and economic disruptions that will be long lasting. There are nuclear risks, both from Russian attacks on Ukrainian nuclear facilities and the potential for nuclear weapons use. There is a further risk that Russia might use chemical or biological weapons. We call for an immediate ceasefire and the appointment of a mediator to facilitate negotiations for a sustainable and peaceful settlement on the basis of international law to end the conflict. We urge the global health community to deliver humanitarian assistance impartially to all those affected by and fleeing the war; document atrocities committed against civilians and the devastating impacts of the war; counter disinformation about the conflict; and advocate for a peaceful settlement. We also call for an end to the repression of those in Russia protesting the war.http://www.thelancet.comhj2023Economic
Acute otitis externa: Consensus definition, diagnostic criteria and core outcome set development.
OBJECTIVE: Evidence for the management of acute otitis externa (AOE) is limited, with unclear diagnostic criteria and variably reported outcome measures that may not reflect key stakeholder priorities. We aimed to develop 1) a definition, 2) diagnostic criteria and 3) a core outcome set (COS) for AOE. STUDY DESIGN: COS development according to Core Outcome Measures in Effectiveness Trials (COMET) methodology and parallel consensus selection of diagnostic criteria/definition. SETTING: Stakeholders from the United Kingdom. SUBJECTS AND METHODS: Comprehensive literature review identified candidate items for the COS, definition and diagnostic criteria. Nine individuals with past AOE generated further patient-centred candidate items. Candidate items were rated for importance by patient and professional (ENT doctors, general practitioners, microbiologists, nurses, audiologists) stakeholders in a three-round online Delphi exercise. Consensus items were grouped to form the COS, diagnostic criteria, and definition. RESULTS: Candidate COS items from patients (n = 28) and literature (n = 25) were deduplicated and amalgamated to a final candidate list (n = 46). Patients emphasised quality-of-life and the impact on daily activities/work. Via the Delphi process, stakeholders agreed on 31 candidate items. The final COS covered six outcomes: pain; disease severity; impact on quality-of-life and daily activities; patient satisfaction; treatment-related outcome; and microbiology. 14 candidate diagnostic criteria were identified, 8 reaching inclusion consensus. The final definition for AOE was 'diffuse inflammation of the ear canal skin of less than 6 weeks duration'. CONCLUSION: The development and adoption of a consensus definition, diagnostic criteria and a COS will help to standardise future research in AOE, facilitating meta-analysis. Consulting former patients throughout development highlighted deficiencies in the outcomes adopted previously, in particular concerning the impact of AOE on daily life
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