Emission time scale of light particles in the system Xe+Sn at 50 AMeV. A probe for dynamical emission ?

Proton and deuteron correlation functions have been investigated with both impact parameter and emission source selections. The correlations of the system (129Xe + natSn) at 50 AMeV have been measured with the 4 pi INDRA which provides a complete kinematical description of each event. The emission time scale analyzed with a quantum model reveals the time sequence of the light particles emitted by the projectile-like fragment. The short and constant emission time of the proton, independent of the impact parameter, can be attributed to a preequilibrium process.Comment: 20 pages, with 11 included figures; Accepted by European Physics Journal

Utilisation de la MLVA pour décrire la dynamique des souches de Streptococcus uberis et diagnostiquer le profil épidémiologique des infections intramammaires dans les troupeaux de vaches laitières

La gestion des mammites à Streptococcus uberis nécessite l application de mesures correctives dépendantes de l épidémiologie de cette bactérie. Afin d améliorer les connaissances de l épidémiologie de cette bactérie, 19 élevages à prévalence d infection à Streptococcus uberis élevée ont été suivis pendant 7 mois. Cinq prélèvements exhaustifs de lait de quartier des vaches en lactation ont été effectués et analysés par Multi Locus VNTR Analysis afin d étudier la diversité des souches ainsi que la dynamique des infections à Streptococcus uberis. Au vu des résultats, deux voies de contamination par Streptococcus uberis existent, la contamination directe depuis l environnement et la contagion à partir de quartiers infectés. Dans une optique diagnostique, la diversité des souches de Streptococcus uberis parait intéressante pour évaluer l importance de la contagion afin d adapter les mesures correctives.NANTES-Ecole Nat.Vétérinaire (441092302) / SudocTOULOUSE-EN Vétérinaire (315552301) / SudocSudocFranceF

Taux d'admission dans les universités des étudiants en provenance des collèges de la région de Montréal

Titre de la couv.: Taux d'admission dans les universités des étudiants en provenance des collèges de la région de Montréa

Art et environnement : prolonger la question de l'habiter

ACLNNational audienceL'environnement interpelle les artistes et les conduit depuis les années 1970 à déplacer leur angle d'intervention et à porter une attention renouvelée aux paysages, aux lieux et aux manières qu'ont les sociétés humaines de les investir. Dans le cadre d'un travail portant sur l'esthétique environnementale, et à partir d'un questionnement théorique interrogeant la manière dont l'environnement intervient dans le champ esthétique, il s'agit de voir de quelle façon certains artistes mobilisent le champ de l'habiter, et d'autres le champ de l'environnement pour introduire de nouvelles modalités de relation de l'art au territoire, notamment urbain. L'étude de projets artistiques permet de repenser la problématique environnementale souvent concentrée sur des dispositifs d'ingénierie. Il s'agit de comprendre les modalités d'une approche artistique et esthétique de l'environnement à la fois sur les plans conceptuel et pratique. Notre hypothèse est que les artistes, expérimentateurs, jouent de l'environnement pour développer de nouvelles manières d'agir sur/avec ce dernier

Hoxa1 and Hoxb1 are required for pharyngeal arch artery development

International audienceHox transcription factors play critical roles during early vertebrate development. Previous studies have revealed an overlapping function of Hoxa1 and Hoxb1 during specification of the rhombomeres from which neural crest cells emerge. A recent study on Hoxa1 mutant mice documented its function during cardiovascular development, however, the role of Hoxb1 is still unclear. Here we show using single and compound Hoxa1; Hoxb1 mutant embryos that reduction of Hoxa1 gene dosage in Hoxb1-null genetic background is sufficient to result in abnormal pharyngeal aortic arch (PAA) development and subsequently in great artery defects. Endothelial cells in the 4th PAAs of compound mutant differentiate normally whereas vascular smooth muscle cells of the vessels are absent in the defective PAAs. The importance of Hoxa1 and Hoxb1, and their interaction during specification of cardiac NCCs is demonstrated. Together, our data reveal a critical role for anterior Hox genes during PAA development, providing new mechanistic insights into the etiology of congenital heart defects. (C) 2016 Elsevier Ireland Ltd. All rights reserved

New Avenue for Mid-UV-Range Detection of Underivatized Carbohydrates and Amino Acids in Capillary Electrophoresis.

International audienceCapillary electrophoresis (CE) appeared as an interesting alternative to chromatographic methods for carbohydrate analysis, but it can be difficult to implement, because of the lack of easily ionizable functions and chromophore groups. Recently, a promising method was proposed by Rovio et al. for the CE separation under extremely high alkaline conditions of neutral carbohydrates under their alcoholate form and their direct UV detection [Rovio et al. Electrophoresis2007, 28, 3129-3135; and Rovio et al. J. Chromatogr. A2008, 1185, 139-144], which is claimed to be due to the absorption of enediolate at 270 nm. Even so, most of the detected compounds in Rovio's paper (for example, sucrose) cannot give such enediolate, lacking a carbonyl group. In this work, a deeper insight was paid to the understanding of detection mechanism. In effect, unusual detection phenomena were observed in comparing reducing and nonreducing carbohydrate behaviors, which pointed to the existence of photochemical reactions in the detection window. A more systematic study of the influence of many parameters (carbohydrate nature, electrolyte pH, residence time in the detection window, and capillary diameter) was undertaken. In addition to this, most of this work was performed under cathodic (reversed) electro-osmotic flow conditions (using Polybrene-modified capillaries), to obtain much faster separations than under Rovio's conditions. This study also opens up new avenues for the detection in mid-UV range of non-UV-absorbing compounds bearing reducing moieties, such as amino acids

Analysis of HOXB1 gene in a cohort of patients with sporadic ventricular septal defect

International audienceVentricular septal defect (VSD) including outlet VSD of double outlet right ventricle (DORV) and perimembranous VSD are among the most common congenital heart diseases found at birth. HOXB1 encodes a homeodomain transcription factor essential for normal cardiac outflow tract development. The aim of the present study was to investigate the possible genetic effect of sequence variations in HOXB1 on VSD. The coding regions and splice junctions of the HOXB1 gene were sequenced in 57 unrelated VSD patients. As a result, a homozygous c.74\₈2dup (p.Pro28delinsHisSerAlaPro) variant was identified in one individual with DORV. We also identified five previously reported polymorphisms (rs35114525, rs12946855, rs14534040, rs12939811, and rs7207109) in 18 patients (12 DORV and 6 perimembranous VSD). Our study did not show any pathogenic alterations in the coding region of HOXB1 among patients with VSD. To our knowledge this is the first study investigating the role of HOXB1 in nonsyndromic VSD, which provide more insight on the etiology of this disease

Prognostic impact of O 6 -methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation

International audienc