20 research outputs found

    Identidad no binaria y la emisión de títulos y certificaciones oficiales con validez nacional en la UNMDP

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    El presente trabajo se propone analizar las implicancias relacionadas con el reconocimiento de la identidad de género, y en particular, de la incorporación de una tercera opción a la categoría "sexo", para la emisión de titulaciones, diplomas y analíticos finales. A partir de la aprobación de la ley 26.743 que reconoce la identidad de género y promulgación del decreto 476/21, que incorpora una tercera opción, no binaria, a la diferenciación masculino-femenino, se genera la necesidad de hacer efectivo este reconocimiento mediante la posibilidad de registrar adecuadamente la información de quienes opten por ejercer estos derechos, así como la posibilidad de emitir la documentación solicitada en concordancia con estas opciones. Para las Universidades Nacionales, uno de los mayores desafíos se relaciona con la emisión de títulos, diplomas y certificaciones oficiales con reconocimiento oficial y validez nacional en los que se refleje este reconocimiento.Fil: Nasarov, Valeria Anabel. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina

    Шаг в водородо-углеродную энергетику

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    Well-known and mid-19-th century widely spread methods of converting solid fuel being considered as ‘‘inconvenient” for usage into so called “universal” gaseous fuel have become non- profitable due to emergence oi cheap natural gas.The paper contains a proposal to reanimate old and half-forgotten gasification methods on the basis of new and higher technological level, namely: continuous decomposition of high temperature water steam by solid fuel carbon with production of gas-generator gas consisting basically of two fuel gases - hydrogen and carbon monoxide (HCM).Хорошо известные и широко распространенные в середине XIX ст. методы преобразования «неудобных» в использовании твердых топлив в более «универсальное» газообразное стали нерентабельны с появлением дешевого природного газа.Предлагается «реанимация» старых методов газификации на новом, более высоком техническом уровне: непрерывным разложением высокотемпературного водяного пара углеродом твердого топлива с получением газогенераторного газа, состоящего в основном из двух горючих газов: водорода и угарного газа

    Step into Hydrogen- and Carbon Power Engineering

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    Well-known and mid-19-th century widely spread methods of converting solid fuel being considered as ‘‘inconvenient” for usage into so called “universal” gaseous fuel have become non- profitable due to emergence oi cheap natural gas.The paper contains a proposal to reanimate old and half-forgotten gasification methods on the basis of new and higher technological level, namely: continuous decomposition of high temperature water steam by solid fuel carbon with production of gas-generator gas consisting basically of two fuel gases - hydrogen and carbon monoxide (HCM)

    Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties

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    Despite the strong evidence linking the aggregation of the Huntingtin protein (Htt) to the pathogenesis of Huntington’s disease (HD), the mechanisms underlying Htt aggregation and neurodegeneration remain poorly understood. Herein, we investigated the ultrastructural properties and protein composition of Htt cytoplasmic and nuclear inclusions in mammalian cells and primary neurons overexpressing mutant exon1 of the Htt protein. Our findings provide unique insight into the ultrastructural properties of cytoplasmic and nuclear Htt inclusions and their mechanisms of formation. We show that Htt inclusion formation and maturation are complex processes that, although initially driven by polyQ-dependent Htt aggregation, also involve the polyQ and PRD domain-dependent sequestration of lipids and cytoplasmic and cytoskeletal proteins related to HD dysregulated pathways; the recruitment and accumulation of remodeled or dysfunctional membranous organelles, and the impairment of the protein quality control and degradation machinery. We also show that nuclear and cytoplasmic Htt inclusions exhibit distinct biochemical compositions and ultrastructural properties, suggesting different mechanisms of aggregation and toxicity.LMN
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