4,279 research outputs found
On the localized phase of a copolymer in an emulsion: supercritical percolation regime
In this paper we study a two-dimensional directed self-avoiding walk model of
a random copolymer in a random emulsion. The copolymer is a random
concatenation of monomers of two types, and , each occurring with
density 1/2. The emulsion is a random mixture of liquids of two types, and
, organised in large square blocks occurring with density and ,
respectively, where . The copolymer in the emulsion has an energy
that is minus times the number of -matches minus times the
number of -matches, where without loss of generality the interaction
parameters can be taken from the cone . To make the model mathematically tractable, we assume that the
copolymer is directed and can only enter and exit a pair of neighbouring blocks
at diagonally opposite corners.
In \cite{dHW06}, it was found that in the supercritical percolation regime , with the critical probability for directed bond percolation on
the square lattice, the free energy has a phase transition along a curve in the
cone that is independent of . At this critical curve, there is a transition
from a phase where the copolymer is fully delocalized into the -blocks to a
phase where it is partially localized near the -interface. In the present
paper we prove three theorems that complete the analysis of the phase diagram :
(1) the critical curve is strictly increasing; (2) the phase transition is
second order; (3) the free energy is infinitely differentiable throughout the
partially localized phase.Comment: 43 pages and 10 figure
On the localized phase of a copolymer in an emulsion: supercritical percolation regime
Article / Letter to editorMathematisch Instituu
Interdisciplinary (retail) research: The business of geography and the geography of business
NoAt the 2005 British Academy of Management conference several well-known economic
geographers, including Neil Wrigley, Gordon Clark, and Susan Christopherson, called
for management researchers to engage with economic geographers on interrelated
geographical and managerial issues in the study of (retail) firms. In this commentary
we reflect upon the present geography -management interface.We begin by considering
the term `interdisciplinary research' and its relationship to any management - geography interface. This is followed by a context-specific discussion of international retailing and the role of research on the retail transnational corporation (TNC) in developing an interdisciplinary agenda. This commentary represents an initial more business and management focused response to the call from geography academics for more/better interdisciplinary research at the geography - management interface
Missense mutations at homologous positions in the fourth and fifth laminin A G-like domains of eyes shut homolog cause autosomal recessive retinitis pigmentosa
Purpose: To describe two novel mutations in the eyes shut homolog (EYS) gene in two families with autosomal recessive
retinitis pigmentosa (arRP) from Pakistan and Indonesia.
Methods: Genome-wide linkage and homozygosity mapping were performed using single nucleotide polymorphism microarray analysis in affected members of the two arRP families. Sequence analysis was performed to identify genetic changes in protein coding exons of EYS.
Results: In the Indonesian and Pakistani families, homozygous regions encompassing the EYS gene at 6q12 were identified, with maximum LOD scores of 1.8 and 3.6, respectively. Novel missense variants in the EYS gene (p.D2767Y and p.D3028Y) were found in the Pakistani and Indonesian families, respectively, that co-segregate with the disease phenotype. Interestingly, the missense variants are located at the same homologous position within the fourth and fifth laminin A G-like domains of EYS.
Conclusions: To date, mostly protein-truncating mutations have been described in EYS, while only few patients have been described with pathogenic compound heterozygous missense mutations. The mutations p.D2767Y and p.D3028Y described in this study affect highly conserved residues at homologous positions in laminin A G-like domains and support the notion that missense mutations in EYS can cause arRP
Occurrence (1956) of Haemoproteus sacharovi and Plasmodium relictum in a Central Iowa Pigeon Colony
Naturally occurring infections of Plasmodium relictum and H aemoproteus sacharovi in pigeons of Central Iowa have recently been reported (Becker, Hollander and Pattillo, 1956). In that survey, involving pigeons of all ages, both microscopic examination of stained blood films and isodiagnosis were employed, but the examination of blood films stained in Giemsa was the sole procedure relied upon in the 1956 survey. The birds concerned were young, ranging in age from two to eight weeks. All belonged to the Central Iowa colony to which reference was made in the previous paper. A total of 114 blood films was examined, distributed by dates as follows: June 29, 32; July 21, 23; September 8, 33; September 18, 26. There were a few duplications among the birds examined on September 8 and September 18. The average ages (in weeks) of the squabs on the four dates were as follows: June 29, 4.7; July 21, 3.7; September 8, 3.6; September 18, 4.4. There were, in addition, two other young squabs which will be discussed later
Rimonabant improves cardiometabolic risk factors in overweight/obese patients with poorly controlled type 2 diabetes (HbA(1c)>= 8%) on monotherapy with metformin or sulfonylureas
peer reviewe
Properties of additive functionals of Brownian motion with resetting
We study the distribution of additive functionals of reset Brownian motion, a
variation of normal Brownian motion in which the path is interrupted at a given
rate and placed back to a given reset position. Our goal is two-fold: (1) For
general functionals, we derive a large deviation principle in the presence of
resetting and identify the large deviation rate function in terms of a
variational formula involving large deviation rate functions without resetting.
(2) For three examples of functionals (positive occupation time, area and
absolute area), we investigate the effect of resetting by computing
distributions and moments, using a formula that links the generating function
with resetting to the generating function without resetting.Comment: 23 pages, 4 figure
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