An international treaty to implement a global compute cap for advanced artificial intelligence

This paper presents an international treaty to reduce risks from the development of advanced artificial intelligence (AI). The main provision of the treaty is a global compute cap: a ban on the development of AI systems above an agreed-upon computational resource threshold. The treaty also proposes the development and testing of emergency response plans, negotiations to establish an international agency to enforce the treaty, the establishment of new communication channels and whistleblower protections, and a commitment to avoid an AI arms race. We hope this treaty serves as a useful template for global leaders as they implement governance regimes to protect civilization from the dangers of advanced artificial intelligence

Multinational AGI Consortium (MAGIC): A Proposal for International Coordination on AI

This paper proposes a Multinational Artificial General Intelligence Consortium (MAGIC) to mitigate existential risks from advanced artificial intelligence (AI). MAGIC would be the only institution in the world permitted to develop advanced AI, enforced through a global moratorium by its signatory members on all other advanced AI development. MAGIC would be exclusive, safety-focused, highly secure, and collectively supported by member states, with benefits distributed equitably among signatories. MAGIC would allow narrow AI models to flourish while significantly reducing the possibility of misaligned, rogue, breakout, or runaway outcomes of general-purpose systems. We do not address the political feasibility of implementing a moratorium or address the specific legislative strategies and rules needed to enforce a ban on high-capacity AGI training runs. Instead, we propose one positive vision of the future, where MAGIC, as a global governance regime, can lay the groundwork for long-term, safe regulation of advanced AI

Spectrometer for X-ray emission experiments at FERMI free-electron-laser

A portable and compact photon spectrometer to be used for photon in-photon out experiments, in particular x-ray emission spectroscopy, is presented. The instrument operates in the 25\u2013800 eV energy range to cover the full emissions of the FEL1 and FEL2 stages of FERMI. The optical design consists of two interchangeable spherical varied-lined-spaced gratings and a CCD detector. Different input sections can be accommodated, with/without an entrance slit and with/without an additional relay mirror, that allow to mount the spectrometer in different end-stations and at variable distances from the target area both at synchrotron and at free-electron-laser beamlines. The characterization on the Gas Phase beamline at ELETTRA Synchrotron (Italy) is presented

Psychological treatments and psychotherapies in the neurorehabilitation of pain. Evidences and recommendations from the italian consensus conference on pain in neurorehabilitation

BACKGROUND: It is increasingly recognized that treating pain is crucial for effective care within neurological rehabilitation in the setting of the neurological rehabilitation. The Italian Consensus Conference on Pain in Neurorehabilitation was constituted with the purpose identifying best practices for us in this context. Along with drug therapies and physical interventions, psychological treatments have been proven to be some of the most valuable tools that can be used within a multidisciplinary approach for fostering a reduction in pain intensity. However, there is a need to elucidate what forms of psychotherapy could be effectively matched with the specific pathologies that are typically addressed by neurorehabilitation teams. OBJECTIVES: To extensively assess the available evidence which supports the use of psychological therapies for pain reduction in neurological diseases. METHODS: A systematic review of the studies evaluating the effect of psychotherapies on pain intensity in neurological disorders was performed through an electronic search using PUBMED, EMBASE, and the Cochrane Database of Systematic Reviews. Based on the level of evidence of the included studies, recommendations were outlined separately for the different conditions. RESULTS: The literature search yielded 2352 results and the final database included 400 articles. The overall strength of the recommendations was medium/low. The different forms of psychological interventions, including Cognitive-Behavioral Therapy, cognitive or behavioral techniques, Mindfulness, hypnosis, Acceptance and Commitment Therapy (ACT), Brief Interpersonal Therapy, virtual reality interventions, various forms of biofeedback and mirror therapy were found to be effective for pain reduction in pathologies such as musculoskeletal pain, fibromyalgia, Complex Regional Pain Syndrome, Central Post-Stroke pain, Phantom Limb Pain, pain secondary to Spinal Cord Injury, multiple sclerosis and other debilitating syndromes, diabetic neuropathy, Medically Unexplained Symptoms, migraine and headache. CONCLUSIONS: Psychological interventions and psychotherapies are safe and effective treatments that can be used within an integrated approach for patients undergoing neurological rehabilitation for pain. The different interventions can be specifically selected depending on the disease being treated. A table of evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation is also provided in the final part of the pape

What is the role of the placebo effect for pain relief in neurorehabilitation? Clinical implications from the Italian consensus conference on pain in neurorehabilitation

Background: It is increasingly acknowledged that the outcomes of medical treatments are influenced by the context of the clinical encounter through the mechanisms of the placebo effect. The phenomenon of placebo analgesia might be exploited to maximize the efficacy of neurorehabilitation treatments. Since its intensity varies across neurological disorders, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCP) summarized the studies on this field to provide guidance on its use. Methods: A review of the existing reviews and meta-analyses was performed to assess the magnitude of the placebo effect in disorders that may undergo neurorehabilitation treatment. The search was performed on Pubmed using placebo, pain, and the names of neurological disorders as keywords. Methodological quality was assessed using a pre-existing checklist. Data about the magnitude of the placebo effect were extracted from the included reviews and were commented in a narrative form. Results: 11 articles were included in this review. Placebo treatments showed weak effects in central neuropathic pain (pain reduction from 0.44 to 0.66 on a 0-10 scale) and moderate effects in postherpetic neuralgia (1.16), in diabetic peripheral neuropathy (1.45), and in pain associated to HIV (1.82). Moderate effects were also found on pain due to fibromyalgia and migraine; only weak short-term effects were found in complex regional pain syndrome. Confounding variables might have influenced these results. Clinical implications: These estimates should be interpreted with caution, but underscore that the placebo effect can be exploited in neurorehabilitation programs. It is not necessary to conceal its use from the patient. Knowledge of placebo mechanisms can be used to shape the doctor-patient relationship, to reduce the use of analgesic drugs and to train the patient to become an active agent of the therapy

What is the role of the placebo effect for pain relief in neurorehabilitation? Clinical implications from the Italian Consensus Conference on Pain in Neurorehabilitation

Background: It is increasingly acknowledged that the outcomes of medical treatments are influenced by the context of the clinical encounter through the mechanisms of the placebo effect. The phenomenon of placebo analgesia might be exploited to maximize the efficacy of neurorehabilitation treatments. Since its intensity varies across neurological disorders, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCP) summarized the studies on this field to provide guidance on its use. Methods: A review of the existing reviews and meta-analyses was performed to assess the magnitude of the placebo effect in disorders that may undergo neurorehabilitation treatment. The search was performed on Pubmed using placebo, pain, and the names of neurological disorders as keywords. Methodological quality was assessed using a pre-existing checklist. Data about the magnitude of the placebo effect were extracted from the included reviews and were commented in a narrative form. Results: 11 articles were included in this review. Placebo treatments showed weak effects in central neuropathic pain (pain reduction from 0.44 to 0.66 on a 0-10 scale) and moderate effects in postherpetic neuralgia (1.16), in diabetic peripheral neuropathy (1.45), and in pain associated to HIV (1.82). Moderate effects were also found on pain due to fibromyalgia and migraine; only weak short-term effects were found in complex regional pain syndrome. Confounding variables might have influenced these results. Clinical implications: These estimates should be interpreted with caution, but underscore that the placebo effect can be exploited in neurorehabilitation programs. It is not necessary to conceal its use from the patient. Knowledge of placebo mechanisms can be used to shape the doctor-patient relationship, to reduce the use of analgesic drugs and to train the patient to become an active agent of the therapy

Pubblica amministrazione e Sud: i nuovi contenuti del divario

Nel corso del tempo si è sviluppata una crescente attenzione ai “nuovi contenuti” del divario di sviluppo del Mezzogiorno con il resto del Paese, che riguardano la pluralità dei servizi essenziali a regolamentazione nazionale e locale, e l’efficienza delle Amministrazioni pubbliche. Ad essi va aggiunta una sostanziale inefficienza dell’ambiente normativo in cui operano le imprese, e stati di attivazione differenziati dei processi di digitalizzazione delle PA, che comunque scontano un generale ritardo nello stato di attuazione. L’azione della PA, tuttavia, sembra essere fortemente orientata a produrre una rottura rispetto a questi andamenti, ed un miglioramento del livello di trasparenza ed efficienza dell’azione amministrativa è già osservabile. Il rischio è che tempi di sperimentazione troppo lunghi e risultati differenziati tra Centro-Nord e Mezzogiorno determinino la sostanziale inefficacia degli interventi progettati

Taking control: Policies to address extinction risks from advanced AI

This paper provides policy recommendations to reduce extinction risks from advanced artificial intelligence (AI). First, we briefly provide background information about extinction risks from AI. Second, we argue that voluntary commitments from AI companies would be an inappropriate and insufficient response. Third, we describe three policy proposals that would meaningfully address the threats from advanced AI: (1) establishing a Multinational AGI Consortium to enable democratic oversight of advanced AI (MAGIC), (2) implementing a global cap on the amount of computing power used to train an AI system (global compute cap), and (3) requiring affirmative safety evaluations to ensure that risks are kept below acceptable levels (gating critical experiments). MAGIC would be a secure, safety-focused, internationally-governed institution responsible for reducing risks from advanced AI and performing research to safely harness the benefits of AI. MAGIC would also maintain emergency response infrastructure (kill switch) to swiftly halt AI development or withdraw model deployment in the event of an AI-related emergency. The global compute cap would end the corporate race toward dangerous AI systems while enabling the vast majority of AI innovation to continue unimpeded. Gating critical experiments would ensure that companies developing powerful AI systems are required to present affirmative evidence that these models keep extinction risks below an acceptable threshold. After describing these recommendations, we propose intermediate steps that the international community could take to implement these proposals and lay the groundwork for international coordination around advanced AI

Robotics in Education: A Smart and Innovative Approach to the Challenges of the 21st Century

none3noRobotics in Education (RiE) is a broad term that refers to a variety of applications. Robots can enhance learning and teaching, but they can also help overcome impairments, whether physical or social. Even though the advantages of bringing new technologies into schools are clear, the lack of a well-established set of good practices, assessment of experiences, and tools slows down their adoption. This chapter aims to highlight the key points that emerge from the recent enhancements in RiE. First, the market and research are continuously developing new tools for school to try to meet needs and tailor products. Second, there is a wealth of formal and non-formal experiences, both in the literature and in school activities. Third, research is still validating tools and methodologies that will assess the impact of introducing robotics into education. Despite the wide availability of tools and experiences, there is still a certain degree of uncertainty about how to cope with technology in education and how to evaluate the outcomes of such activities. The increasing cross-pollination between schools and researchers from different fields is producing valuable experiences that will soon close the gap.noneScrepanti Laura; Miotti Beatrice; Monteriu' AndreaScrepanti, Laura; Miotti, Beatrice; Monteriu', Andre

Marine Seagrasses Transplantation in Confined and Coastal Adriatic Environments: Methods and Results

The anthropogenic pressures of the twentieth century have seriously endangered the Mediterranean coastal zone; as a consequence, marine seagrass habitats have strongly retreated, mostly those of Posidonia oceanica. For this reason, over time, restoration programs have been put in place through transplantation activities, with different success. These actions have also been conducted with other Mediterranean marine seagrasses. The results of numerous transplanting operations conducted in the Northern Adriatic Sea and lagoons with Cymodocea nodosa, Zostera marina and Z. noltei and in the Central and Southern Adriatic Sea with P. oceanica (only within the project Interreg SASPAS), are herein presented and compared, taking also into account the presence of extensive meadows of C. nodosa, Z. marina and Z. noltei, along the North Adriatic coasts and lagoons