On the development of a web-based toolkit for supporting reviews of the quality and contents of iStar requirements models(iStar要求仕様モデルのクオリティとコンテンツ検証用のオンラインツールキットの開発について）

信州大学(Shinshu university)博士（工学）ThesisMEJRI　HAJER. On the development of a web-based toolkit for supporting reviews of the quality and contents of iStar requirements models(iStar要求仕様モデルのクオリティとコンテンツ検証用のオンラインツールキットの開発について）. 信州大学, 2017, 博士論文. 博士（工学）, 甲第677号, 平成29年09月30日授与.doctoral thesi

Insights on How to Enhance the Detection of Modeling Errors by iStar Novice Learners

When teaching a new paradigm which involves practical training to a large group of students, it often becomes time-consuming and impractical for a single instructor to give advice on an individual basis on how to correct errors being made and the need for computer-aided assistants arises.  In this work, we focus on the i* (iStar) framework which is being used to teach requirements engineering and modeling techniques to undergraduate and graduate students in the classroom.  We proposed and developed an online tool for automating the work of checking the design constructs used in i* diagrams so that novice learners could detect and correct errors on their own without the assistance of a human expert nearby.  Although the tool was useful in showing novice learners how to edit their models to make them free of syntax errors, there were a number of situations in which they could not recognize the semantical design flaws and defects of a model using the feedback from the tool.  In this paper, we give examples of the errors we observed and recommend a new tool which will automatically generate a human understandable textual annotation of the main model elements and the relationships connecting them to assist beginners as well as non-technical stakeholders involved in the requirement decisions of a system with detecting simple misrepresentations of information of this type that need to be rectified in the model. 

Pleistocenne marine paleoshorelines along the eastern coast of Tunisia : IRSL chronology, paleoenvironments and tectonic regime

Sur la côte du Sahel tunisien, les dépôts littoraux pléistocènes sont organisés en trois formations marines distinctes : Douira, Réjiche et Chebba définies par Paskoff et Sanlaville (1976) et redéfinies ultérieurement par Mahmoudi (1988) en unités lithostratigraphiques Douira, Khniss et Rejiche. Cependant, il n’a pas toujours été aisé de préciser la chronostratigraphie, la répartition géographique, et le rapport tectonique/eustatisme au cours du Pléistocène moyen et supérieur. La présente thèse se propose d’établir des subdivisions chronostratigraphiques régionales en s’appuyant sur la méthode de datation par luminescence IRSL. Les âges IRSL obtenus pour l’ensemble des dépôts littoraux pléistocènes (marins, lagunaires et dunaires) du Cap Bon oriental, du Sahel et du SE tunisien, s’échelonnent entre 335 ka et 66 ka. Ils se répartissent en six ensembles corrélés aux MIS 9, MIS 7, MIS 6/5, MIS 5.5, MIS 5.3/5.1 indifférencié et MIS 4. Ces âges IRSL démontrent qu’au Sahel, les dépôts marins littoraux pré-tyrrhéniens attribués à l’unité Douira sont corrélatifs de deux hauts niveaux marins interglaciaires distincts corrélables au MIS 9 et au MIS 7. Les âges IRSL des dépôts littoraux tyrrhéniens de la côte Est tunisienne (unités de Khniss et de Rejiche au Sahel), jusqu’ici attribués au MIS 5.5, s’inscrivent dans une chronologie beaucoup plus longue qui s’étend de la transition du MIS 6/5.5 au MIS 4. L’analyse tectonique de détail des populations de plans striés et des systèmes de joints qui affectent les unités littorales du Pléistocène moyen et supérieur (MIS 9 à MIS 4) a permis de préciser le régime tectonique et de déterminer les différents tenseurs de contrainte. Ceux-ci ont été classés et comparés en fonction des données chronostratigraphiques. Les nouvelles données lithostratigraphiques, chronologiques, sédimentologiques et tectoniques acquises dans le cadre de cette thèse sont ensuite replacées dans le contexte plus large de la Méditerranée occidentale.Along the coast of the Tunisian Sahel, the Pleistocene littoral deposits are organized into three distinct marine formations: Douira, Rejiche and Chebba defined by Paskoff and Sanlaville (1976) and later redefined by Mahmoudi (1988) in terms of lithostratigraphic units Douira, Khniss and Réjiche. However, the chronostratigraphy, the distribution and the relationship between tectonics and eustatism during the Middle and Upper Pleistocene remained so far problematic. The present thesis offers to establish regional chronostratigraphic subdivisions by means of IRSL luminescence dating. The IRSL ages of the Pleistocene littoral deposits (marine, lagoonal and eolian) from the eastern Cap Bon peninsula, the Sahel area and Southeastern Tunisia, are ranging between 335 ka and 66 ka. They are subdivided into six units correlative with MIS 9, MIS 7, MIS 6/5, MIS 5.5, MIS 5.3/5.1 and MIS 4. These IRSL ages demonstrate that the pre-tyrrhenian littoral deposits assigned to the Douira unit belong to two distinct marine interglacial high stands correlative of MIS 9 and MIS 7. The IRSL results of the Tyrrhenian littoral deposits from eastern Tunisia (Khniss and Rejiche units), so far assigned to MIS 5.5, are consistent with a longer chronology that extends from the MIS 6/5 transition to MIS 4. The detailed tectonic analysis of fault populations and joint sets data affecting these Middle and Upper Pleistocene littoral units (MIS 9 to MIS 4) enabled to specify the tectonic regime. It also helped to ascertain the different stress tensors. The latter were classified and compared with each other according to the chronostratigraphic data. The new lithostratigraphic, chronological, sedimentological and tectonic data obtained in this thesis are then replaced in the context of the western Mediterranean basin

Datation IRSL des dépôts lagunaires pléistocènes de la côte orientale de la Tunisie

Les séquences littorales du Pléistocène supérieur et moyen préservées le long de la côte orientale de Tunisie, renferment plusieurs niveaux lagunaires représentés par des dépôts limoneux souvent pédogénéisés. Ces dépôts fournissent d’importants repères chronostratigraphiques et constituent de précieux indicateurs pour la reconstitution des paléoenvironnements et l’histoire des zones humides.Cependant, ces dépôts lagunaires pléistocènes, signalés dans différentes parties du littoral tunisien, sont restés, en comparaison avec les formations marines franches, peu étudiés et surtout mal ou non datés. Etant dépourvus de matériel datable par la méthode U-Th et étant inaccessibles à la méthode 14C, leur âge n’avait pu jusqu’ici être précisé.Dans le cadre de la présente étude, une méthode de datation alternative est mise en œuvre : la méthode de luminescence et plus particulièrement la méthode IRSL (« Infra Red Stimulated Luminesence ») qui est ici appliquée aux grains de feldspaths détritiques du sédiment lagunaire. Nous présentons ici les dates IRSL obtenues sur des dépôts lagunaires préservés au sein de quatre séquences littorales de référence pour le dernier interglaciaire (stade isotopique marin ou SIM 5 ; 130-74 ka). Il s’agit des séquences d’Hergla, de Khniss et de Chebba au Sahel et de la séquence de Sidi Yati sur l’Île de Jerba. Ces dates IRSL sont ensuite comparées à l’âge IRSL d’un dépôt lagunaire du SIM 7 préservé à Dar Oufa au Cap Bon oriental (MEJRI et al., 2014).Cette étude chronologique démontre l’existence de deux épisodes lagunaires distincts au sein des séquences littorales attribuées au SIM 5. Ces nouvelles données IRSL fournissent ainsi un nouvel éclairage sur la chronostratigraphie des séquences littorales de Tunisie orientale attribuées au SIM 5.Several lagoonal deposits, mainly consisting of pedogenised loamy sediment, are preserved within the Upper and Middle Pleistocene coastal sequences along the eastern coast of Tunisia. These deposits provide important chronostratigraphic markers and significant indicators for the reconstruction of paleoenvironments and the wetlands history.Outcrops of these lagoonal deposits are widely distributed along the Tunisian coast but they remain poorly known and dated in comparison with the marine deposits. Given the absence of material datable by the U/Th method and the inapplicability of the 14C method, their age has not yet been clearly established.In the present study, an alternative dating method is performed : the luminescence dating method, and more particularly the IRSL method (“Infra Red Stimulated Luminesence”) which is applied herein to the feldspar detrital grains of the lagoonal sediments. We present herein the IRSL dates obtained on lagoonal deposits preserved within four Last Interglacial (MIS 5, 130-74 ka) key littoral sequences : the Hergla, Khniss and Chebba sequences in the Sahel area and the Sidi Yati sequence on the Jerba island. These IRSL data will be compared with the IRSL age obtained for the SIM 7 lagoonal deposit preserved at Dar Oufa along the eastern coast of the Cap Bon Peninsula (MEJRI et al., 2014).This chronological study demonstrates the existence of two separate lagoonal episodes within the coastal sequences assigned to MIS 5. Hence, this IRSL dating investigation provides new insight into the chronostratigraphy of the MIS 5 coastal sequences of eastern Tunisia

Privacy and Intelligent Virtual Assistants Usage across Generations

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Management of Kounis syndrome: two case reports

Abstract Background Kounis syndrome corresponds to the occurrence of myocardial injury following an allergic insult. This syndrome is infrequent, and is not well known. In consequence, it is usually misdiagnosed leading to inappropriate treatment. The current literature is limited to case studies and there are no international recommendations concerning this topic. Case presentation We discussed, through two case reports, the clinical presentation and the management of a 60-year-old North African man and a 45-year-old North African man presenting with chest pain suggesting acute coronary syndrome following anaphylactic reaction. Triggering factors were a drug in the first case and herbal dermal exposure in the second. A clinical examination and electrocardiogram revealed anaphylactic reaction associated with myocardial infarction. Appropriate management of these two life-threatening conditions allowed an improvement in our patients’ condition and their transfer to specialized units. Conclusions Although Kounis syndrome is a rare phenomenon, physicians should be aware of its physiopathological mechanisms in order to treat it appropriately. The difficulty lies in the fact that the treatment of either of the two associated entities may worsen the other injury

Assessment of Coastal Vulnerability to Erosion Risk Using Geospatial and Remote Sensing Methods (Case of Jerba Island, Tunisia)

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Mise en évidence par la luminescence des feldspaths de deux hauts niveaux marins interglaciaires du Pléistocène moyen (MIS 7 et MIS 9) le long de la côte orientale de la Tunisie (Sahel)

La méthode de datation IRSL sur feldspaths alcalins (200-250 μm) est appliquée aux deux unités marines sableuses, dépourvues de Strombes et d’oolithes, de la Formation Douira, unité morphostratigraphique caractéristique du Pléistocène moyen marin du Sahel tunisien. Les âges IRSL de ces deux unités marines, obtenus à El Hajeb, à proximité de la localité type de Douira au Sahel, confirment l’âge pré-tyrrhénien de la Formation Douira. Ils démontrent par ailleurs, pour la première fois, l’existence au sein de cette formation, de deux hauts niveaux marins distincts, corrélatifs des MIS 7 et 9. Ces deux unités marines sableuses sont séparées à El Hajeb, par une surface d’érosion majeure et à Réjiche, par un limon continental pédogénéisé témoignant d’un épisode de bas niveau marin qui pourrait être corrélé au MIS 8. Nous proposons donc ici de subdiviser cette Formation Douira en deux membres, inférieur et supérieur, attribués respectivement aux MIS 9 et 7. Ces deux hauts niveaux marins sont contemporains des hauts niveaux lacustres du sud-ouest tunisien et de Libye ainsi que des sapropèles du bassin méditerranéen.The IRSL dating method is applied to alkali feldspar grains (200-250 μm) from the two sandy marine units of the Douira Formation, a Middle Pleistocene morphostratigraphic marine unit specific to the Tunisian Sahel area. This formation is devoid of Strombus bubonius and ooids. The IRSL ages of both marine units, obtained at El Hajeb, close to the type locality of Douira in the Sahel area, confirm the pre-tyrrhenian age of the Douira Formation. Moreover, they demonstrate, for the first time, the presence of two successive interglacial high sea-level events within the Douira Formation, correlative of MIS 7 and MIS 9. These sandy marine units are separated, at El Hajeb, by a major erosional surface and, at Rejiche, by a continental pedogenised loamy deposit related to a low sea-level event that might be assigned to MIS 8. We therefore suggest herein to subdivide the Douira Formation into two members, a lower and an upper member correlated respectively with MIS 9 and 7. Both high sea-level stands coincide with the development of extensive Middle Pleistocene paleolakes in south-western Tunisia and Libya and the formation of sapropels in the Mediterranean basin

Immunological characterization of a non-toxic peptide conferring protection against the toxic fraction (AahG50) of the Androctonus australis hector venom.

KAaH1 and KAaH2 are non-toxic peptides, isolated from the venom of the Androctonus australis hector (Aah) scorpion. In a previous study, we showed these peptides to be the most abundant (approximately 10% each) in the toxic fraction (AahG50) of the Aah venom. KAaH1 and KAaH2 showed high sequence identities (approximately 60%) with birtoxin-like peptides, which likewise are the major peptidic components of Parabuthus transvaalicus scorpion venom. Here, we report the immunological characterization of KAaH1 and KAaH2. These peptides were found to be specifically recognized by polyclonal antibodies raised against AahII, the most toxic peptide of Aah venom, and represents the second antigenic group, including toxins from different scorpion species in the world. Moreover, KAaH1 partially inhibits AahII binding to its specific antibody, suggesting some common epitopes between these two peptides. The identification of possible key antigenic residues in KAaH1 was deduced from comparison of its 3-D model with the experimental structure of AahII. Two clusters of putative antigenically important residues were found at the exposed surface; one could be constituted of V3 and D53, the other of D10, T15 and Y16. Polyclonal antibodies raised against KAaH1 in mice were found to cross-react with both AahII and AahG50, and neutralizing 5LD(50)/ml of the toxic fraction. Mice vaccinated with KAaH1 were protected against a challenge of 2LD(50) of AahG50 fraction. All these data suggest that KAaH1 has clear advantages over the use of the whole or part of the venom. KAaH1 is not toxic and could produce sera-neutralizing scorpion toxins, not only from Aah venom, but also toxins of other venoms from Buthus, Leiurus, or Parabuthus scorpion species presenting antigenically related toxins

Parsonage–Turner syndrome of the brachial plexus secondary to COVID‐19 vaccine: A case report

Abstract Parsonage–Turner syndrome (PTS) is a peripheral inflammatory neuropathy of unknown etiology. We present a rare case of a 50‐year‐old male patient with PTS post‐COVID‐19 BNT162b2 mRNA vaccine. Symptoms occurred 15 days after the second dose. He was treated with corticosteroids, analgesics, and physical rehabilitation with a partial recovery