Power Allocation and Cooperative Diversity in Two-Way Non-Regenerative Cognitive Radio Networks

In this paper, we investigate the performance of a dual-hop block fading cognitive radio network with underlay spectrum sharing over independent but not necessarily identically distributed (i.n.i.d.) Nakagami-$m$ fading channels. The primary network consists of a source and a destination. Depending on whether the secondary network which consists of two source nodes have a single relay for cooperation or multiple relays thereby employs opportunistic relay selection for cooperation and whether the two source nodes suffer from the primary users' (PU) interference, two cases are considered in this paper, which are referred to as Scenario (a) and Scenario (b), respectively. For the considered underlay spectrum sharing, the transmit power constraint of the proposed system is adjusted by interference limit on the primary network and the interference imposed by primary user (PU). The developed new analysis obtains new analytical results for the outage capacity (OC) and average symbol error probability (ASEP). In particular, for Scenario (a), tight lower bounds on the OC and ASEP of the secondary network are derived in closed-form. In addition, a closed from expression for the end-to-end OC of Scenario (a) is achieved. With regards to Scenario (b), a tight lower bound on the OC of the secondary network is derived in closed-form. All analytical results are corroborated using Monte Carlo simulation method

Quality of life in people with diabetes: a systematic review of studies in Iran.

Evaluation of health-related quality of life (HRQoL) among people with diabetes has been growing in Iran over the last decade. The main aim of the current study was to systematically review the characteristics of these studies and examine quality of their findings. Persian (SID, Magiran) and English (Pubmed, Medline, Web of Science, CINAHL, Scopus, PsycINFO and ERIC) databases were systematically searched using the search terms: "diabetes" AND "quality of life" AND "Iran". The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. A total of 46 studies passed the inclusion criteria and were included in the review. The included studies were conducted in 20 out of 30 provinces of the country. Most studies investigated HRQoL among people with type 2 diabetes. The Short Form Health Survey (SF-36) and WHO quality of life instruments (WHOQOL) were the main instruments used in these studies. Studies showed that people with diabetes had lower HRQoL than people without diabetes. Better socioeconomic status and better control of cardiovascular risk factors were associated with better HRQoL among the patients with diabetes. In general, the predictors of HRQoL among Iranian patients were similar to their international counterparts implying that diabetes patients share many common features. The reviewed studies suffer from major methodological and reporting flaws which limit validity and generalizability of their findings

Assessment of the Synergism Effect of Imatinib and Temozolomide on Serum Levels and Activities of Matrix Metalloproteinases 2 and 9 (MMP2, 9) in U87-Mg Glioma Cell Line

Introduction: One of the most dangerous brain tumors is Glioblastoma multiforme (GBM).The MMPs are very important biomarker in pathologic conditions and be known as metastatic factor. Temozolomide is an oral alkylating agent, and has a good effect on GBM. Gefitinib is a low–molecular weight tyrosine kinase inhibitor that is used in tratmeant of tumor. Methods and Results: The human GBM cell line, U87 mg was obtained from Pasteur Institute of Iran. Cells grown in RPMI 1640 supplemented with 10% fetal bovine serum in a humidified incubator at 370C with 5% CO2. Cell viability after treatment, was measured by MTT test. MMP-2, MMP-9, Quantikine® ELISA kits (R&D systems, Minneapolis, USA) were used to measure supernatants MMPs. Effect of the drugs on the enzyme  activity of MMP-2 and MMP-9 was assessed by gelatin zymography. Synergism of Temozolomide and Imatinib can reduce the IC50 of temozolomide. Our results show that combination of Imatinib and Temozolomide decreased the level and activity of MMP-2 and MMP-9 in supernatant of culture medium versus to control cells when only Temozolomide or Imatinib was added to their culture medium. Conclusion: Combination of Imatinib as a tyrosine kinase inhibitor and Temozolomide as an alkylating agent is more potent than Temozolomide and it can reduce IC50 and decrease level and activitity of MMP-2 and MMP-9.The current strategies for treatment of glioblastoma are not beneficial enough. Combination therapy probably can reduce the dose of drug, cost of treatment, adverse effects and increase the survival rate of life

The effect of motor imaginary combined with Transcranial Direct Current Stimulation (TDCS) on balance in middle-aged women with high fall risk : a double-blind randomized controlled trial

Introduction. The risk of falling and its subsequent injuries increases with aging. Impaired balance and gait are important contributing factors to the increased risk of falling. A wide range of methods was examined to improve balance, but these interventions might produce small effects or be inapplicable for this population. The current study aimed at investigating the effect of motor imaginary (MI) training combined with transcranial direct current stimulation (tDCS) over the cerebellum on balance in middle-aged women with high fall risk. Methods. Thirty subjects aged 40-65 years old were divided into two groups including intervention (n=15) and sham control (n=15). The participants completed a 4-week program 3 times per week. The intervention group performed MI training combined with tDCS over the cerebellum, and the control group performed MI training combined with sham tDCS over the cerebellum. Static and dynamic balance were measured at baseline and after completing the 4-week program using balance error scoring system (BESS) and Y balance testing, respectively. Result. A one-way analysis of covariance and paired t-tests were used to analyze the data. Significant improvement was observed in both balance tests in the intervention group after the implementation of the 4-week intervention program compared to the control group. The within-group analysis showed that both static and dynamic balance improved significantly from the baseline values only in the intervention group (p0.05). Conclusion. The results of the study indicate that MI training combined with tDCS over the cerebellum can lead to balance improvement in middle-aged women with high fall risk. © 2023 Esmaeil Mozafaripour et al

The effective major factors on customer perceived value in service context: The application of ANFIS method

The purpose of the research is to further explore the understanding of the major factors influencing on service customer perceived value by undertaking Adaptive Neuro-Fuzzy Inference System (ANFIS) method in fuzzy inference system (FIS). A total of 162 questionnaires were distributed to educational institute customers. In this research effective major factors on customer perceived value are brand image, company image, employee trust, company trust, service quality and costs. The results show that in the field of education, the company image and the costs are the most effective elements on the customer perceived value. Also employee trust and service quality have positive effects on the customer perceived value, but they were not very most. Thus educative services institutes must concentrate more on the company image and costs reduction in order to increase the customer perceived value.

Protective effects of licorice extract on ovarian morphology, oocyte maturation, and embryo development in PCOS-induced mice: An experimental study

Background: Polycystic ovary syndrome (PCOS) is an oxidative state resulting in ovarian dysfunction. Licorice is one of the natural antioxidants used for the treatment of infertility. Objective: To evaluate the effect of licorice extract on ovarian morphology, oocyte maturation, and embryo development in PCOS-induced mice. Materials and Methods: thirty-two female NMIR mice were divided into four groups (n = 8/each): control group receiving no treatment (group I); PCOS group injected with estradiol valerate once daily for 21 days (group II); and experimental groups receiving either 100 mg/kg (group III) or 150 mg/kg (group IV) licorice by gavage along with estradiol valerate once daily for 3 wk. Serum levels of the testosterone and estrogen were measured using ELISA kit. Histological study of ovaries was evaluated, and oocyte maturation, fertilization rate, and embryo development were determined after in vitro maturation. Results: Experimental groups (III, IV) had significantly higher testosterone and estradiol levels compared to the PCOS group (p ≤ 0.001). A significant increase in the number of healthy follicles (primary, preantral follicles) (p = 0.001), corpus luteum (p = 0.001) with significant decrease in the number of atretic follicles (primary, preantral, cystic follicles) (p ≤ 0.001) was seen in the experimental groups. Increase in the fertilization rate (p ≤ 0.001) and blastocyst stage embryos (p = 0.02, p = 0.004) were observed in the experimental groups. Conclusions: It appears that the two doses (100 mg and 150 mg) of licorice could decrease ovarian cyst and improve the fertilization rate of oocyte and embryo development in PCOS mice. However, there was no statistically significant difference between the two experimental groups. Key words: Polycystic ovary syndrome, Mice, Licorice, Histology, In vitro maturation, In vitro fertilization

The effective major factors on customer perceived value in service context: The application of ANFIS method

The purpose of the research is to further explore the understanding of the major factors influencing on service customer perceived value by undertaking Adaptive Neuro-Fuzzy Inference System (ANFIS) method in fuzzy inference system (FIS). A total of 162 questionnaires were distributed to educational institute customers. In this research effective major factors on customer perceived value are brand image, company image, employee trust, company trust, service quality and costs. The results show that in the field of education, the company image and the costs are the most effective elements on the customer perceived value. Also employee trust and service quality have positive effects on the customer perceived value, but they were not very most. Thus educative services institutes must concentrate more on the company image and costs reduction in order to increase the customer perceived value.

Effects of fennel, asafetida and ginseng ethanolic extracts on growth and proliferation of mouse breast cancer 4T1 cell lines

Background: The 4T1 cells tumor growth and metastatic pattern in BALB/c mice very closely mimic human breast cancer. These herbal remedies used in traditional folk medicine have been the source of many medically beneficial drugs. The aim of the current study was to evaluate the anti-proliferative activity of the asafoetida, ginseng and fennel ethanolic extracts on mouse breast cancer 4T1 cell-line invitro.Method: in this experimental study, Asafoetida, gensing and fennel were extracted; 4T1 mouse mammary tumor cell line were cultured in 48-well flat bottom plate in density of 50x103 per well in 100 µl RPMI1640 medium then different dilutions of each extract (25 , 50, 100, 200, 500, and 2000 μg/ml) were added to cell culture. Cells then were incubated at 37 oC for 24 hours. After 24 h, cell Proliferation was determined by the BRDU assay . dataset of experiments were collected and analysed with SPSS19 software. Significant level of Data was Examined with one-way ANOVA method and

Study of Pluto's Atmosphere Based on 2020 Stellar Occultation Light Curve Results

On 6 Jun 2020, Pluto's stellar occultation was successfully observed at a ground-based observatory and Pluto's atmospheric parameters were investigated. We used an atmospheric model of Pluto (DO15), assuming a spherical and transparent pure N2 atmosphere. Using ray-tracing code the stellar occultation light curve was satisfactorily fitted to this model. We found that Pluto's atmospheric pressure at the reference radius of 1215 km is 6.72+_0.21 {\mu}bar. Our estimated pressure shows a continuation of the increasing pressure studied in 2016 consistent with a seasonal volatile transport model. We concluded that the N2 condensation processes in the Sputnik Planitia glacier are increasing due to the heating of the N2 ice in this basin. This study's result was shown on the diagram of the annual evolution of atmospheric pressure.Comment: 4 figures, 2 table