2,901 research outputs found

    Empirical rheology and pasting properties of soft-textured durum wheat (Triticum turgidum ssp. durum) and hard-textured common wheat (T. aestivum)

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    Puroindoline (PIN) proteins are the molecular basis for wheat kernel texture classification and affect flour milling performance. This study investigated the effect of PINs on empirical rheology and pasting properties in Triticum turgidum ssp. durum and Triticum aestivum. Soft wheat (cv. Alpowa), durum wheat (cv. Svevo) and their derivatives in which PINs were deleted (Hard Alpowa) or expressed (cv. Soft Svevo). Presence of PINs affected flour particle size and damaged starch. PINs increased the pasting temperature and breakdown viscosity, while the effect on peak viscosity and setback were not consistent. Presence of PINs was negatively associated with GlutoPeak gluten aggregation energy and farinograph dough stability, suggesting a weakening of the gluten matrix. As regards dough extensibility, the role of PINs was evident only in common wheat: 5DS distal end deletion increased the resistance to extension, without affecting the dough extensibility. This study showed PINs to have different impact on pasting and rheological properties of T. aestivum and T. turgidum ssp. durum flours

    Conservative, special-relativistic smoothed particle hydrodynamics

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    We present and test a new, special-relativistic formulation of Smoothed Particle Hydrodynamics (SPH). Our approach benefits from several improvements with respect to earlier relativistic SPH formulations. It is self-consistently derived from the Lagrangian of an ideal fluid and accounts for special-relativistic "grad-h terms". In our approach, we evolve the canonical momentum and the canonical energy per baryon and thus circumvent some of the problems that have plagued earlier formulations of relativistic SPH. We further use a much improved artificial viscosity prescription which uses the extreme local eigenvalues of the Euler equations and triggers selectively on a) shocks and b) velocity noise. The shock trigger accurately monitors the relative density slope and uses it to fine-tune the amount of artificial viscosity that is applied. This procedure substantially sharpens shock fronts while still avoiding post-shock noise. If not triggered, the viscosity parameter of each particle decays to zero. None of these viscosity triggers is specific to special relativity, both could also be applied in Newtonian SPH. The performance of the new scheme is explored in a large variety of benchmark tests where it delivers excellent results. Generally, the grad-h terms deliver minor, though worthwhile, improvements. The scheme performs close to perfect in supersonic advection tests, but also in strong relativistic shocks, usually considered a particular challenge for SPH, the method yields convincing results. For example, due to its perfect conservation properties, it is able to handle Lorentz-factors as large as γ=50  000\gamma= 50 \; 000 in the so-called wall shock test. Moreover, we find convincing results in a rarely shown, but challenging test that involves so-called relativistic simple waves and also in multi-dimensional shock tube tests.Comment: 39 pages, 19 figures, Journal of Computational Physics in press, reference upate

    Structural consequences of the interaction of puroindolines with gluten proteins

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    The effect of puroindolines (PINs) on structural characteristics of wheat proteins was investigated in Triticum turgidum ssp. durum (cv. Svevo) and Triticum aestivum (cv. Alpowa) and in their respective derivatives in which PIN genes were expressed (Soft Svevo) or the distal end of the short arm of chromosome 5D was deleted and PINs were not expressed (Hard Alpowa). The presence of PINs decreased the amount of cold-SDS extractable proteins and the accessibility of protein thiols to specific reagents, but resulted in facilitated solvation of gluten proteins, as detected by tryptophan fluorescence measurements carried out on minimally mixed flour/water mixtures. We propose that PINs and gluten proteins are interacting in the grain or flour prior to mixing. Hydrophobic interactions between PINs and some of the gluten proteins modify the pattern of interactions among gluten proteins, thus providing an additional mechanistic rationale for the effects of PINs on kernel hardness

    A Minimal Intervention to Promote Smoke-Free Homes among 2-1-1 Callers: North Carolina Randomized Effectiveness Trial

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    This study examined the extent to which delivery of the minimal Smoke-Free Homes intervention by trained 2-1-1 information and referral specialists had an effect on the adoption of home smoking bans in low-income households. A randomized controlled trial was conducted among 2-1-1 callers (n = 500) assigned to control or intervention conditions. 2-1-1 information and referral specialists collected baseline data and delivered the intervention consisting of 3 mailings and 1 coaching call; university-based data collectors conducted follow-up interviews at 3 and 6 months post-baseline. Data were collected from June 2013 through July 2014. Participants were mostly female (87.2%), African American (61.4%), and smokers (76.6%). Participants assigned to the intervention condition were more likely than controls to report a full ban on smoking in the home at both 3- (38.1% vs 19.3%, p = < .001) and 6-month follow-up (43.2% vs 33.2%, p = .02). The longitudinal intent-to-treat analysis showed a significant intervention effect over time (OR = 1.31, p = .001), i.e. OR = 1.72 at 6 months. This study replicates prior findings showing the effectiveness of the minimal intervention to promote smoke-free homes in low-income households, and extends those findings by demonstrating they can be achieved when 2-1-1 information and referral specialists deliver the intervention. Findings offer support for this intervention as a generalizable and scalable model for reducing secondhand smoke exposure in homes

    Cancer control needs of 2-1-1 callers in Missouri, North Carolina, Texas, and Washington

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    Innovative interventions are needed to connect underserved populations to cancer control services. With data from Missouri, North Carolina, Texas, and Washington this study a) estimated the cancer control needs of callers to 2-1-1, an information and referral system used by underserved populations, b) compared rates of need to state and national data, and c) examined receptiveness to needed referrals. From October 2009 to March 2010 callers’ (N = 1408) cancer control needs were assessed in six areas: breast, cervical, and colorectal cancer screening, HPV vaccination, smoking, and smoke-free homes using Behavioral Risk Factor Surveillance System (BRFSS) survey items. Standardized estimates were compared to state and national rates. Nearly 70% of the sample had at least one cancer control need. Needs were greater for 2-1-1 callers compared to state and national rates, and callers were receptive to referrals. 2-1-1 could potentially be a key partner in efforts to reduce cancer disparities

    Simultaneous multiwavelength observations of the Low/Hard State of the X-ray transient source SWIFT J1753.5-0127

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    We report the results of simultaneous multiwavelength observations of the X-ray transient source SWIFT J1753.5-0127 performed with INTEGRAL, RXTE, NTT, REM and VLA on 2005 August 10-12. The source, which underwent an X-ray outburst since 2005 May 30, was observed during the INTEGRAL Target of Opportunity program dedicated to new X-ray novae located in the Galactic Halo. Broad-band spectra and fast timing variability properties of SWIFT J1753.5-0127 are analyzed together with the optical, near infra-red and radio data. We show that the source was significantly detected up to 600 keV with Comptonization parameters and timing properties typical of the so-called Low/Hard State of black hole candidates. We build a spectral energy distribution and we show that SWIFT J1753.5-0127 does not follow the usual radio/X-ray correlation of X-ray binaries in the Low/Hard State. We give estimates of distance and mass. We conclude that SWIFT J1753.5-0127 belongs to the X-ray nova class and that it is likely a black hole candidate transient source of the Galactic Halo which remained in the Low/Hard State during its main outburst. We discuss our results within the context of Comptonization and jet models.Comment: Accepted for publication in ApJ, 25 pages, 4 tables, 11 figures (3 in color

    Dissemination of Strongyloides stercoralis in a patient with systemic lupus erythematosus after initiation of albendazole: a case report

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    <p>Abstract</p> <p>Introduction</p> <p><it>Strongyloides stercoralis </it>infection affects hundreds of millions of people worldwide. As immigration rates and international travel increase, so does the number of cases of strongyloidiasis in the United States. Although described both in immigrant and in immunosuppressed populations, hyperinfection and dissemination of <it>S. stercoralis </it>following the initiation of antiparasitic medication is a previously unreported phenomenon.</p> <p>Case presentation</p> <p>Here we describe the case of a 38-year-old immunocompromised woman with systemic lupus erythematosus, who developed disseminated disease following treatment with albendazole (400 mg every 12 hours). Notably the patient was receiving oral prednisone (10 mg once daily), azathioprine (50 mg twice daily), and hydroxychloroquine (400 mg daily) at the time of hospitalization. The patient was subsequently treated successfully with ivermectin (200 mcg/kg daily).</p> <p>Conclusion</p> <p>The reader should be aware that dissemination of <it>S. stercoralis </it>can occur even after the initiation of antiparasitic medication.</p
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