Evaluación de la ergonomía en la logística

Durante mucho tiempo la prevención de riesgos laborales en la empresa se ha concebido como una sucesión de operaciones aisladas y autónomas cuyo único objetivo era cumplir con el marco legal que la rodeaDepartamento de Organización de Empresas y Comercialización e Investigación de MercadosMáster en Logístic

Influence of Digitalization in Business and Industry. Analysis and Implementation of Thingsee One Device

En el proyecto se explican conceptos sobre digitalización como IoT, Cloud Services, Big Data… Así como conceptos de mercado. Estos se fusionan para lograr la digitalización del mercado. De modo práctico se llevan a cabo con un dispositivo, llamado “Thingsee One”, diferentes casos en los que se muestran los resultadosDepartamento de Química AnalíticaGrado en Ingeniería en Organización Industria

Control manual para CNC

El objetivo del proyecto es diseñar un control manual para controlar un CNC (Control Numérico por Computadora) de forma no automática. A lo largo del proyecto en primer lugar se estudiará la tarjeta HY-TB4DV-M obteniendo sus esquemas mediante ingeniería inversa para diseñar de la manera más apropiada el Control Manual aquí descrito. En segundo lugar se realizará el diseño y fabricación del prototipo para la posterior comprobación de su correcto funcionamiento. En tercer lugar se procederá a programar el prototipo mediante la plataforma Arduino dotando al proyecto de las funcionalidades y características deseadas. Por último se hará el diseño final del Control Manual para CNC a partir del prototipo optimizando las características que hayan ofrecido margen de mejora. La finalidad última de este proyecto es la fabricación y comercialización del diseño para el usuario final que desee un control manual fácil de usar e intuitivo.Departamento de Tecnología ElectrónicaIngeniero Técnico de Telecomunicación, Especialidad en Sistemas Electrónico

Técnicas de Geovisualización aplicadas al Paisaje Cultural y el Patrimonio: el caso de Atauta

La integración por un lado de la perspectiva espacial en el análisis del paisaje a través de conceptos escalares, territorio, ubicación, distancia, proximidad y lejanía, o elementos que lo configuran como objetos constructivos, vegetación..., y de otro lado el uso de las tecnologías de geovisualización y la información geográficamente referenciada, sirven de eje para abordar en el presente caso la investigación del BIC Conjunto Etnológico de bodegas de Atauta

Intense precipitation events in the Central Range of the Iberian Peninsula

Intense orographic precipitation associated with the Central Range was analysed using data of maximum accumulated precipitation in 24 h, occurring between 1958 and 2010. The 18 selected episodes were associated with a southwesterly tropospheric flow, a low-level jet, and high moisture flux at low levels. The observed moisture flux was higher than 100 (m g(s kg)−1) and the dry and wet Froude numbers were greater than 1. The selected area to study this synoptic situation was Gredos, broad and high range, which is located in the eastern part of the Central Range and generates a leeward “orographic shadow”. The effect of the Central Range on the spatial distribution of precipitation on the Iberian Peninsula plateau results in a sharp increase in precipitation in the south of the Central Range, followed by a decrease to the north of this range

A Unified Framework for Reservoir Computing and Extreme Learning Machines based on a Single Time-delayed Neuron

In this paper we present a unified framework for extreme learning machines and reservoir computing (echo state networks), which can be physically implemented using a single nonlinear neuron subject to delayed feedback. The reservoir is built within the delay-line, employing a number of “virtual” neurons. These virtual neurons receive random projections from the input layer containing the information to be processed. One key advantage of this approach is that it can be implemented efficiently in hardware. We show that the reservoir computing implementation, in this case optoelectronic, is also capable to realize extreme learning machines, demonstrating the unified framework for both schemes in software as well as in hardware

Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors

The R-RAS2 GTP hydrolase (GTPase) (also known as TC21) has been traditionally considered quite similar to classical RAS proteins at the regulatory and signaling levels. Recently, a long-tail hotspot mutation targeting the R-RAS2/TC21 Gln72 residue (Q72L) was identified as a potent oncogenic driver. Additional point mutations were also found in other tumors at low frequencies. Despite this, little information is available regarding the transforming role of these mutant versions and their relevance for the tumorigenic properties of already-transformed cancer cells. Here, we report that many of the RRAS2 mutations found in human cancers are highly transforming when expressed in immortalized cell lines. Moreover, the expression of endogenous R-RAS2Q72L is important for maintaining optimal levels of PI3K and ERK activities as well as for the adhesion, invasiveness, proliferation, and mitochondrial respiration of ovarian and breast cancer cell lines. Endogenous R-RAS2Q72L also regulates gene expression programs linked to both cell adhesion and inflammatory/immune-related responses. Endogenous R-RAS2Q72L is also quite relevant for the in vivo tumorigenic activity of these cells. This dependency is observed even though these cancer cell lines bear concurrent gain-of-function mutations in genes encoding RAS signaling elements. Finally, we show that endogenous R-RAS2, unlike the case of classical RAS proteins, specifically localizes in focal adhesions. Collectively, these results indicate that gain-of-function mutations of R-RAS2/TC21 play roles in tumor initiation and maintenance that are not fully redundant with those regulated by classical RAS oncoproteins

マスメディアおよびソーシャルメディアの利用が震災復興に与える効果 -理論的枠組み-

Peer reviewe

A GIS-supported Multidisciplinary Database for the Management of UNESCO Global Geoparks: the Courel Mountains Geopark (Spain)

[Abstract] The management of a UNESCO Global Geopark (UGGp) requires a vast wealth of miscellaneous scientific knowledge that can be successfully organised using a Geographical Information System (GIS). This paper presents a pragmatic GIS database to assist in the suitable governance of the Courel Mountains UGGp (2017) in Northwest Spain. The database is structured in 66 coverages compiled from public sources and previous works or produced through traditional mapping (combining fieldwork and photointerpretation) and GIS tools. The acquired data was later homogenised and validated by a multidisciplinary team and archived in independent coverages. Forty thematic maps illustrate the broad range of cartographic information included in the GIS database. Among them, 25 basic maps provide an overview of the UGGp and 15 new maps focus on crosscutting and technical issues. All maps illustrate the huge potential of GIS to create new resources combining coverages and adapting the legend according to their purpose and audience. The database facilitates the suitable publishing of consistent outputs (e.g., brochures, books, panels, webpages, web serves), as well as the elaboration of technical data to assist the park management. The database furnishes information on the design of education actions, touristic routes, activities and Geopark facilities. The GIS database is also a supportive tool for scientific research and provides the necessary knowledge to conduct geoconservation actions based on land use, geological hazards and the occurrence of natural and cultural heritages. Altogether, the GIS database constitutes a powerful instrument for policy-making, facilitating the identification and evaluation of alternative strategy plans.This work was developed in the framework of the Scientific Program of the Courel Mountains UGGp with the cooperation of tourism agents (A.M. Arza and A. López), roofing slate quarries (Pizarras de Villarbacú, Pizarras de Quiroga) and local people (M. Reinosa, G. Díaz, O. Álvarez). We are deeply grateful to J.R. Martínez Catalán (Universidad de Salamanca), A. Pérez-Alberti and J. Guitián (both from Universidade de Santiago de Compostela), J.R. Gutiérrez-Marco (ICOG, Universidad Complutense de Madrid/CSIC), J. Vegas (IGME-CSIC), L. González-Menéndez (IGME-CSIC), J.M. García Queijeiro (Universidade de Vigo), L. Santos and A. Grandal-D’Anglade (both from Universidade da Coruña) for their assistance supplying information involved in the database. We thank also E. de Boer for proofreading the article. DB is grant holder of Plan Andaluz de Investigación, Desarrollo e Innovación 2021, funded by Junta de Andalucí