62 research outputs found
Preterm gut microbiota and metabolome following discharge from intensive care
The development of the preterm gut microbiome is important for immediate and longer-term health following birth. We aimed to determine if modifications to the preterm gut on the neonatal intensive care unit (NICU) impacted the gut microbiota and metabolome long-term. Stool samples were collected from 29 infants ages 1â3 years post discharge (PD) from a single NICU. Additional NICU samples were included from 14/29 infants. Being diagnosed with disease or receiving increased antibiotics while on the NICU did not significantly impact the microbiome PD. Significant decreases in common NICU organisms including K. oxytoca and E. faecalis and increases in common adult organisms including Akkermansia sp., Blautia sp., and Bacteroides sp. and significantly different Shannon diversity was shown between NICU and PD samples. The metabolome increased in complexity, but while PD samples had unique bacterial profiles we observed comparable metabolomic profiles. The preterm gut microbiome is able to develop complexity comparable to healthy term infants despite limited environmental exposures, high levels of antibiotic administration, and of the presence of serious disease. Further work is needed to establish the direct effect of weaning as a key event in promoting future gut health
Criteria and Indicators to Define Priority Areas for Biodiversity Conservation in Vietnam
Balancing biodiversity conservation with land use for agricultural production is a major societal challenge. Conservation activities must be prioritized since funds and resources for conservation are insufficient in the context of current threats, and conservation competes with other societal priorities. In order to contribute to conservation priority-setting literature, we applied an environmental model, PressureâStateâResponse (PSR), to develop a set of criteria for identifying priority areas for biodiversity conservation in Vietnam. Our empirical data have been compiled from 185 respondents and categorized into three groups: Governmental Administration and Organizations, Universities and Research Institutions, and Protected Areas. The Analytic Hierarchy Process (AHP) theory was used to identify the weight of all criteria. Our results show that the priority levels for biodiversity conservation identified by these three factors are 41% for âPressureâ, 26% for âStateâ, and 33% for âResponseâ. Based on these three factors, seven criteria and seventeen indicators were developed to determine priority areas for biodiversity conservation. Besides, our study also reveals that the groups of Governmental Administration and organizations and Protected Areas put a focus on the âPressureâ factor, while the group of Universities and Research Institutions emphasized the importance of the âResponseâ factor in the evaluation process. We suggest that these criteria and indicators be used to identify priority areas for biodiversity conservation in Vietnam
Improved Cauchy radius for scalar and matrix polynomials
We improve the Cauchy radius of both scalar and matrix polynomials, which is
an upper bound on the moduli of the zeros and eigenvalues, respectively, by
using appropriate polynomial multipliers.Comment: 12 page
Landbedeckung in Sachsen, 1961-1979 (Teil 1): Erfassung von VerÀnderungen in der Landbedeckung in Sachsen 1961-1979: Analyse anhand historischer CORONA- Spionageaufnahmen und tiefer neuronaler Netze (Teil 1)
Inhalt des Berichtes ist es, methodische Grundlagen zu schaffen, welche fĂŒr die Landbedeckungskartierung und -klassifizierung aus Satellitenbildern verwendet werden können. Das Ziel ist es, trotz wechselnder Datenquellen eine einheitliche und vergleichbare Datengrundlage aufzubauen. Es wurde dabei eine lange Zeitreihe, welche in der Mitte der 1960er Jahre startet, als Geodatensatz erstellt und auf erste AnwendungsfĂ€lle getestet. Der Bericht ist nach den beiden grundsĂ€tzlich unterschiedlichen methodischen AnsĂ€tzen in zwei Teile aufgetrennt: Teil 1 ist die Schriftenreihe des LfULG, Heft 6/2023 âLandbedeckung in Sachsen 1961-1979â; Teil 2 ist die Schriftenreihe des LfULG, Heft 7/2023 âLandbedeckung in Sachsen 1985 â 2020. Die Veröffentlichung richtet sich sowohl an das Fachpublikum als auch an Laien, die sich fĂŒr die Fernerkundung interessieren.
Redaktionsschluss: 30.11.202
Stool bacterial load in preterm infants with necrotising enterocolitis
Resected gut tissue in necrotising enterocolitis (NEC) has a higher bacterial load than controls. Quantitative PCR was performed on longitudinal NEC and control stool samples (n = 72). No significant difference in the total bacterial load was found between samples at diagnosis compared to controls or temporally within NEC
Development of the preterm gut microbiome in twins at risk of necrotising enterocolitis and sepsis
The preterm gut microbiome is a complex dynamic community influenced by genetic and environmental factors and is implicated in the pathogenesis of necrotising enterocolitis (NEC) and sepsis. We aimed to explore the longitudinal development of the gut microbiome in preterm twins to determine how shared environmental and genetic factors may influence temporal changes and compared this to the expressed breast milk (EBM) microbiome. Stool samples (n = 173) from 27 infants (12 twin pairs and 1 triplet set) and EBM (n = 18) from 4 mothers were collected longitudinally. All samples underwent PCR-DGGE (denaturing gradient gel electrophoresis) analysis and a selected subset underwent 454 pyrosequencing. Stool and EBM shared a core microbiome dominated by Enterobacteriaceae, Enterococcaceae, and Staphylococcaceae. The gut microbiome showed greater similarity between siblings compared to unrelated individuals. Pyrosequencing revealed a reduction in diversity and increasing dominance of Escherichia sp. preceding NEC that was not observed in the healthy twin. Antibiotic treatment had a substantial effect on the gut microbiome, reducing Escherichia sp. and increasing other Enterobacteriaceae.
This study demonstrates related preterm twins share similar gut microbiome development, even within the complex environment of neonatal intensive care. This is likely a result of shared genetic and immunomodulatory factors as well as exposure to the same maternal microbiome during birth, skin contact and exposure to EBM. Environmental factors including antibiotic exposure and feeding are additional significant determinants of community structure, regardless of host genetics
<scp>ReSurveyEurope</scp>: A database of resurveyed vegetation plots in Europe
AbstractAimsWe introduce ReSurveyEurope â a new data source of resurveyed vegetation plots in Europe, compiled by a collaborative network of vegetation scientists. We describe the scope of this initiative, provide an overview of currently available data, governance, data contribution rules, and accessibility. In addition, we outline further steps, including potential research questions.ResultsReSurveyEurope includes resurveyed vegetation plots from all habitats. Version 1.0 of ReSurveyEurope contains 283,135 observations (i.e., individual surveys of each plot) from 79,190 plots sampled in 449 independent resurvey projects. Of these, 62,139 (78%) are permanent plots, that is, marked in situ, or located with GPS, which allow for high spatial accuracy in resurvey. The remaining 17,051 (22%) plots are from studies in which plots from the initial survey could not be exactly relocated. Four data sets, which together account for 28,470 (36%) plots, provide only presence/absence information on plant species, while the remaining 50,720 (64%) plots contain abundance information (e.g., percentage cover or coverâabundance classes such as variants of the BraunâBlanquet scale). The oldest plots were sampled in 1911 in the Swiss Alps, while most plots were sampled between 1950 and 2020.ConclusionsReSurveyEurope is a new resource to address a wide range of research questions on fineâscale changes in European vegetation. The initiative is devoted to an inclusive and transparent governance and data usage approach, based on slightly adapted rules of the wellâestablished European Vegetation Archive (EVA). ReSurveyEurope data are ready for use, and proposals for analyses of the data set can be submitted at any time to the coordinators. Still, further data contributions are highly welcome.</jats:sec
- âŠ