2,342 research outputs found

    Industrial Policies and Growth: Lessons from International Experience

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    The application of industrial policies (IP) to direct resources to industries considered preponderant in achieving growth has been the chosen road by many emerging economies to tackle underdevelopment. Subsidized loans, variable taxes and differentiated tariffs are frequently used. Because of the successful experiences of some South Asian industrial policies, other emerging countries feel tempted of replicating the formula. However, these should be sure first that their governments have the necessary competencies. There are also two questions to ask on the role of IPs in the growth of these countries: first, Were IPs the dominant factor in the countries’ accelerated growth? The neoclassical approach offers an alternative explanation, that the Asian miracle was mainly the result of strong macroeconomic policies implemented. The second question is: Can the problems of some Asian economies in the 1990s be explained by the prolonged application of IPs? This article finds evidence to support that economic growth was due to strong macroeconomic foundations, such as fiscal discipline, controlled inflation and adequate real exchange rate levels. These variables were the driving forces that created high levels of saving and investment. On the other hand, the implementation of IPs is difficult in a globalized world where the regulations of international trade have become very important.

    Higgs-regularized three-loop four-gluon amplitude in N=4 SYM: exponentiation and Regge limits

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    We compute the three-loop contribution to the N=4 supersymmetric Yang-Mills planar four-gluon amplitude using the recently-proposed Higgs IR regulator of Alday, Henn, Plefka, and Schuster. In particular, we test the proposed exponential ansatz for the four-gluon amplitude that is the analog of the BDS ansatz in dimensional regularization. By evaluating our results at a number of kinematic points, and also in several kinematic limits, we establish the validity of this ansatz at the three-loop level. We also examine the Regge limit of the planar four-gluon amplitude using several different IR regulators: dimensional regularization, Higgs regularization, and a cutoff regularization. In the latter two schemes, it is shown that the leading logarithmic (LL) behavior of the amplitudes, and therefore the lowest-order approximation to the gluon Regge trajectory, can be correctly obtained from the ladder approximation of the sum of diagrams. In dimensional regularization, on the other hand, there is no single dominant set of diagrams in the LL approximation. We also compute the NLL and NNLL behavior of the L-loop ladder diagram using Higgs regularization.Comment: 45 pages, 9 figures; v3: major revision (more stringent tests, discussion of order of limits in the Regge regime

    Investigation into New Ground Based Communications Service Offerings in Response to SmallSat Trends

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    The number of NASA sponsored Small Satellite (SmallSat) missions is expected to continue to grow rapidly in the next decade and beyond. There is a growing trend towards more ambitious SmallSat missions, including formation flying (Constellation, Cluster, Trailing) SmallSats and SmallSats destined for lunar orbit and beyond. This paper will present an overview of new service offerings the NASA Near Earth Network (NEN) is currently investigating and demonstrating. It will describe the benefits that new service offerings such as Multiple Spacecraft Per Aperture (MSPA), Ground-based Phased Array (GBPA) antennas, Ground Based Electronically Steered Array (GBESA), and Ground-based Antenna Arraying (GBAA) could provide to individual or formation flying SmallSats anywhere from low-earth orbit to the Sun-Earth Lagrange point orbits. It will also present potential implementation options for future demonstrations at the NASA Goddard Space Flight Center (GSFC) Wallops Flight Facility (WFF) as well as goals and objectives of such demonstrations

    Consistent improvement with eculizumab across muscle groups in myasthenia gravis

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    Objective: To assess whether eculizumab, a terminal complement inhibitor, improves patient- and physician-reported outcomes (evaluated using the myasthenia gravis activities of daily living profile and the quantitative myasthenia gravis scale, respectively) in patients with refractory anti-acetylcholine receptor antibody-positive generalized myasthenia gravis across four domains, representing ocular, bulbar, respiratory, and limb/gross motor muscle groups. Methods: Patients with refractory anti-acetylcholine receptor antibody-positive generalized myasthenia gravis were randomized 1:1 to receive either placebo or eculizumab during the REGAIN study (NCT01997229). Patients who completed REGAIN were eligible to continue into the open-label extension trial (NCT02301624) for up to 4 years. The four domain scores of each of the myasthenia gravis activities of daily living profile and the quantitative myasthenia gravis scale recorded throughout REGAIN and through 130 weeks of the open-label extension were analyzed. Results: Of the 125 patients who participated in REGAIN, 117 enrolled in the open-label extension; 61 had received placebo and 56 had received eculizumab during REGAIN. Patients experienced rapid improvements in total scores and all four domain scores of both the myasthenia gravis activities of daily living profile and the quantitative myasthenia gravis scale with eculizumab treatment. These improvements were sustained through 130 weeks of the open-label extension. Interpretation: Eculizumab treatment elicits rapid and sustained improvements in muscle strength across ocular, bulbar, respiratory, and limb/gross motor muscle groups and in associated daily activities in patients with refractory anti-acetylcholine receptor antibody-positive generalized myasthenia gravis

    BlueFix: Using Crowd-sourced Feedback to Support Programming Students in Error Diagnosis and Repair

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    Feedback is regarded as one of the most important influences on student learning and motivation. But standard compiler feedback is designed for experts - not novice programming students, who can find it difficult to interpret and understand. In this paper we present BlueFix, an online tool currently integrated into the BlueJ IDE which is designed to assist programming students with error diagnosis and repair. Unlike existing approaches, BlueFix proposes a feedback algorithm based upon frameworks combined from the HCI and Pedagogical domains, which can provide different students with dynamic levels of support based upon their compilation behaviour. An evaluation revealed that students' viewed our tool positively and that our methodology could identify appropriate fixes for uncompilable source code with a significantly higher rate of speed and precision over related techniques in the literature

    Randomized trial of complete versus lesion-only revascularization in patients undergoing primary percutaneous coronary intervention for STEMI and Multivessel Disease

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    BACKGROUND: The optimal management of patients found to have multivessel disease while undergoing primary percutaneous coronary intervention (P-PCI) for ST-segment elevation myocardial infarction is uncertain.   OBJECTIVES: CvLPRIT (Complete versus Lesion-only Primary PCI trial) is a U.K. open-label randomized study comparing complete revascularization at index admission with treatment of the infarct-related artery (IRA) only.   METHODS: After they provided verbal assent and underwent coronary angiography, 296 patients in 7 U.K. centers were randomized through an interactive voice-response program to either in-hospital complete revascularization (n = 150) or IRA-only revascularization (n = 146). Complete revascularization was performed either at the time of P-PCI or before hospital discharge. Randomization was stratified by infarct location (anterior/nonanterior) and symptom onset (≤3 h or >3 h). The primary endpoint was a composite of all-cause death, recurrent myocardial infarction (MI), heart failure, and ischemia-driven revascularization within 12 months.   RESULTS: Patient groups were well matched for baseline clinical characteristics. The primary endpoint occurred in 10.0% of the complete revascularization group versus 21.2% in the IRA-only revascularization group (hazard ratio: 0.45; 95% confidence interval: 0.24 to 0.84; p = 0.009). A trend toward benefit was seen early after complete revascularization (p = 0.055 at 30 days). Although there was no significant reduction in death or MI, a nonsignificant reduction in all primary endpoint components was seen. There was no reduction in ischemic burden on myocardial perfusion scintigraphy or in the safety endpoints of major bleeding, contrast-induced nephropathy, or stroke between the groups.   CONCLUSIONS: In patients presenting for P-PCI with multivessel disease, index admission complete revascularization significantly lowered the rate of the composite primary endpoint at 12 months compared with treating only the IRA. In such patients, inpatient total revascularization may be considered, but larger clinical trials are required to confirm this result and specifically address whether this strategy is associated with improved survival. (Complete Versus Lesion-only Primary PCI Pilot Study [CvLPRIT]; ISRCTN70913605)

    Deer Meat as the Source for a Sporadic Case of Escherichia coli O157:H7 Infection, Connecticut1

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    We report a case of Escherichia coli O157:H7, which was acquired by eating wild White-Tailed deer (Odocoileus virginianus). DNA fingerprint analysis verified venison as the source of infection. This pediatric case emphasizes the need for dissemination of information to hunters regarding the safe handling and processing of venison
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