Création de Gateway par un agent intelligent

International audienceLe World Wide Web s'accroît de manière exponentielle depuis le début des années 90. Internet qui était une ressource incontestable d'information est en train de devenir un tel foisonnement d'informations qu'il devient difficile de trouver l'information recherchée. Il faut donc parallèlement à la croissance d'Internet, associer des outils de collecte et de captage de l'information de plus en plus efficace. Pour des recherches d'informations sur des thématiques précises, l'utilisation de gateway parait idéale, car il permet de rassembler tous les serveurs traitant d'un même thème. Mais le problème réside dans la construction et dans la mise à jour de ces gateways. L'avantage premier de la construction des gateways par un agent intelligent est bien évidemment le gain de temps. L'utilisation d'agents intelligents pour la création de gateways est indispensable pour les professionnels de l'information. Ces gateways seront de meilleur qualité, nécessiteront très peu de temps à leur confection, et apporteront une valeur-ajoutée sous formes d'analyses complémentaires

La méthodologie et la stratégie de recherche d'information à valeur-ajoutée sur Internet

International audienceLa croissance exponentielle que connaît Internet impose aux spécialistes de l'information une méthodologie dans leur collecte d'informations. En effet, outre le World Wide Web que tous les utilisateurs connaissent, Internet recèle d'autres sources, à savoir les listes de diffusion, les groupes de discussion... Ces sources sont également extrêmement riches en informations de toutes sortes (experts du domaine, rapports de recherche, technologie-clé...). Dans le langage documentaire, ces sources correspondent à de l'information informelle qui a dans la plupart des cas, une valeur-ajoutée indispensable dans la prise de décision. Tout ceci nécessite donc une bonne stratégie de recherche

A Multimethodological Characterization of Cannabis sativa L. Inflorescences from Seven Dioecious Cultivars Grown in Italy: The Effect of Different Harvesting Stages

The chemical profile of the female inflorescence extracts from seven Cannabis sativa L. dioecious cultivars (Carmagnola, Fibranova, Eletta Campana, Antal, Tiborszallasi, Kompolti, and Tisza) was monitored at three harvesting stages (4, 14, and 30 September), reaching from the be ginning of flowering to end of flowering/beginning of seed formation, using untargeted nuclear magnetic resonance (NMR) and targeted (ultra-high-performance liquid chromatography (UHPLC) and spectrophotometry) analyses. The tetrahydrocannabinol content was always below the legal limits (<0.6%) in all the analyzed samples. The NMR metabolite profile (sugars, organic acids, amino acids, and minor compounds) subjected to principal components analysis (PCA) showed a strong variability according to the harvesting stages: samples harvested in stage I were characterized by a high content of sucrose and myo-inositol, whereas the ones harvested in stage II showed high levels of succinic acid, alanine, valine, isoleucine, phenylalanine, and threonine. Samples harvested in stage III were characterized by high levels of glucose, fructose, choline, trigonelline, malic acid, formic acid, and some amino acids. The ratio between chlorophylls and carotenoids content indicated that all plants grew up exposed to the sun, the Eletta Campana cultivar having the highest pigment amount. Tiborszallasi cultivar showed the highest polyphenol content. The highest antioxidant activity was generally observed in stage II. All these results suggested that the Cannabis sativa L. inflorescences of each analyzed dioecious hemp cultivar presented a peculiar chemical profile affected by the harvesting stage. This information could be useful for producers and industries to harvest inflorescences in the appropriate stage to obtain samples with a peculiar chemical profile suitable for proper applications.15s

Antioxidant Properties of Aminoethylcysteine Ketimine Decarboxylated Dimer: A Review

Aminoethylcysteine ketimine decarboxylated dimer is a natural sulfur-containing compound detected in human plasma and urine, in mammalian brain and in many common edible vegetables. Over the past decade many studies have been undertaken to identify its metabolic role. Attention has been focused on its antioxidant properties and on its reactivity against oxygen and nitrogen reactive species. These properties have been studied in different model systems starting from plasma lipoproteins to specific cellular lines. All these studies report that aminoethylcysteine ketimine decarboxylated dimer is able to interact both with reactive oxygen and nitrogen species (hydrogen peroxide, superoxide anion, hydroxyl radical, peroxynitrite and its derivatives). Its antioxidant activity is similar to that of Vitamin E while higher than other hydrophilic antioxidants, such as trolox and N-acetylcysteine

Prevalence of hepatic steatosis in patients with type 2 diabetes and response to glucose-lowering treatments. A multicenter retrospective study in Italian specialist care

Type 2 diabetes (T2D) is a risk factor for metabolic dysfunction-associated fatty liver disease (MAFLD), which is becoming the commonest cause of chronic liver disease worldwide. We estimated MAFLD prevalence among patients with T2D using the hepatic steatosis index (HSI) and validated it against liver ultrasound. We also examined whether glucose-lowering medications (GLM) beneficially affected HSI

Similar effectiveness of dapagliflozin and GLP-1 receptor agonists concerning combined endpoints in routine clinical practice: A multicentre retrospective study

Aims According to cardiovascular outcome trials, some sodium-glucose contransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) are recommended for secondary cardiovascular prevention in type 2 diabetes (T2D). In this real-world study, we compared the simultaneous reductions in HbA1c, body weight and systolic blood pressure after initiation of dapagliflozin or GLP-1RA as second or a more advanced line of therapy. Materials and methods DARWIN-T2D was a retrospective multi-centre study conducted at diabetes specialist clinics in Italy that compared T2D patients who initiated dapagliflozin or GLP-1RA (exenatide once weekly or liraglutide). Data were collected at baseline and at the first follow-up visit after 3 to 12 months. The primary endpoint was the proportion of patients achieving a simultaneous reduction in HbA1c, body weight and systolic blood pressure. To reduce confounding, we used multivariable adjustment (MVA) or propensity score matching (PSM). Results Totals of 473 patients initiating dapagliflozin and 336 patients initiating GLP-1RA were included. The two groups differed in age, diabetes duration, HbA1c, weight and concomitant medications. The median follow-up was 6 months in both groups. Using MVA or PSM, the primary endpoint was observed in 30% to 32% of patients, with no difference between groups. Simultaneous reduction of HbA1c, BP and SBP by specific threshold, as well as achievement of final goals, did not differ between groups. GLP-1RA reduced HbA1c by 0.3% more than the reduction achieved with dapagliflozin. Conclusion In routine specialist care, initiation of dapagliflozin can be as effective as initiation of a GLP-1RA for attainment of combined risk factor goals

Création automatique de bases de données préformatées: Information issue de l'internet pour la Veille Technologie et l'Intelligence

International audienc

How to hold a Virtual Library Active?

During these past five years, the Internet phenomenon has been marked by a tremendous growth of users as well as the amount of available information. Since then, Internet has been inevitable for the information specialists and the network of networks has many advantages: a lower cost medium of communication, user-friendly, a world wide means of communication and exchange and mostly an open way of providing dynamically information to all. Because of its very different nature, searching information on the Internet becomes ever more harder. The user has to be familiar with index search, in order to find the right information. But the unbelievable growth of information sources available on the Internet makes these tools more and more inefficient. Actually, a new generation of index search has sprung off. These tools relieve the user of the repetitive commands associated with online browsing. These tools are called "Intelligent Agent". We propose in this article how can we use an intelligent agent to create and to hold a virtual library active

How to hold a virtual library active?

During these past five years, the Internet phenomenon has been marked by a tremendous growth of users as well as the amount of available information. Since then, Internet has been inevitable for the information specialists and the network of networks has many advantages: a lower cost medium of communication, user-friendly, a world wide means of communication and exchange and mostly an open way of providing dynamically information to all. Because of its very different nature, searching information on the Internet becomes ever more harder. The user has to be familiar with index search, in order to find the right information. But the unbelievable growth of information sources available on the Internet makes these tools more and more inefficient. Actually, a new generation of index search has sprung off. These tools relieve the user of the repetitive commands associated with online browsing. These tools are called «Intelligent Agent». We propose in this article how can we use an intelligent agent to create and to hold a virtual library activePeer reviewe