126 research outputs found
Expanding the Paradigms of Plant Pathogen Life History and Evolution of Parasitic Fitness beyond Agricultural Boundaries
- Author
- A Alonso
- A Baakza
- A Casadevall
- A Casadevall
- A Collmer
- A Idnurum
- A Schouten
- ACR da Silva
- AT Cruz
- AY Peleg
- B Huber
- BA McDonald
- BD Sun
- Benoit Moury
- BN Lee
- BPHJ Thomma
- C Albert-Weissenberger
- C Hof
- C Pruzzo
- C Ratledge
- CA Da Silva
- CE Morris
- CE Morris
- Cindy E. Morris
- CL Bender
- CO Jarrett
- CR Rausch
- D Palmero Llamas
- D Prusky
- D Vereecke
- D White
- David C. Sands
- DL Arnold
- EJ Cother
- F Thieme
- FH Yildiz
- G Del Sorbo
- G Greub
- G Reguera
- GA Cangelosi
- GD Franc
- Glenn F. Rall
- GY Liu
- H Ilves
- H Nikaido
- H Schoonbeek
- HH Divon
- HJ Schoonbeek
- HP Bais
- I Bjedov
- IK Toth
- J Frohlich-Nowoisky
- J Nechwatal
- J Tans-Kersten
- JC Setubal
- JD Castello
- JD Castello
- JJ Mes
- JL Martinez
- JL Parke
- JL Reedy
- K Ikeda
- KS Bell
- L Hall-Stoodley
- L Keller
- L Rohmer
- LH Hwang
- Linda L. Kinkel
- LW Burgess
- M Lindeberg
- M Schrettl
- M Viaud
- Marc Bardin
- MD Bolton
- MD Harrison
- MJ Larkin
- MJ Pallen
- ML Berbee
- ML Putnam
- NJ McCarter-Zorner
- OR Azmi
- P Reignault
- P Sanchez
- PH Thrall
- Philippe C. Nicot
- QA Mandeel
- R Baker
- R de Jonge
- R Loria
- RA Etzel
- RC Fillhart
- RF Vesonder
- RHY Jiang
- RJ St. Leger
- S Kamoun
- S Manulis
- S Sonjak
- SJ Gould
- SL Annis
- T Rouxel
- WA Oleszek
- YK Han
- Z Hubálek
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2009
- Field of study
International audienc
Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption
- Author
- A Champigneulle
- A Hoffman
- A Nizet
- A Oksche
- A Raes
- A Rojek
- AI Masyuk
- AJ Rouch
- AK Ahrabi
- AK Bhunia
- AK Hughes
- B Mandon
- B Mandon
- B Yang
- B Yang
- BA Jackson
- BD Welch
- BK Kishore
- BK Kishore
- BK Tamarappoo
- BK Yoder
- BM Christensen
- BS Magenheimer
- BW McDill
- BWM Balkom Van
- C Boccalandro
- C Boulter
- C Helies-Toussaint
- C Li
- C Li
- C Lopez-Rodriguez
- C Sette
- CA Ecelbarger
- CA Ecelbarger
- CJ Davidow
- CJ Ward
- CJ Ward
- CL Chou
- CM Turner
- CM Turner
- CR Kennedy
- CW Bourque
- D Brown
- D Brown
- D Lorenz
- D Marples
- D Marples
- D Marples
- D Prie
- D Sun
- D Wenkert
- DE Kohan
- DJ Lloyd
- DL Beene
- DL Xu
- E Klussmann
- E Kusano
- E Schlatter
- E Sohara
- EC Aromataris
- EF Fleming
- EJ Kamsteeg
- EJ Kamsteeg
- EJ Kamsteeg
- EJ Kamsteeg
- EJ Kamsteeg
- EM Schwiebert
- EM Schwiebert
- F Mattia De
- F Mattia De
- F Qian
- F Umenishi
- FA Belibi
- FD Smith
- G Kang
- G Kang
- G Procino
- G Tamma
- G Tamma
- G Tamma
- G Tamma
- G Tamma
- G Valenti
- G Valenti
- G Valenti
- GM Fick
- H Lu
- H Nonoguchi
- H Nonoguchi
- H Nonoguchi
- H Simon
- H Xiong
- HA Lu
- I Jo
- I Teitelbaum
- J Frokiaer
- J Garvin
- J Hughes
- J Rooij de
- JC Hay
- JD Hoffert
- JD Hoffert
- JD Hoffert
- JG Verbalis
- JH Earm
- JH Robben
- JH Robben
- JJ Carlisle Michel
- JL Bos
- JL Gooch
- JM Sands
- JM Sands
- JS Han
- JW Barclay
- JY Chu
- K Fushimi
- K Hanaoka
- K Hanaoka
- K Kasono
- K Kim
- K Tomita
- KA Hillman
- KA Hillman
- KA Strait
- KL Dodge-Kafka
- KP Yip
- KP Yip
- L Bankir
- L Li
- L Pang
- L Tsiokas
- LA Lapierre
- LN Nejsum
- LS Barak
- M Birnbaumer
- M Bisceglia
- M Bustamante
- M Herrera
- M Ikeda
- M Ikeda
- M Kuwahara
- M Yamaki
- M Yasui
- M Zelenina
- MA Bailey
- MA Dillingham
- MA Knepper
- MD Breyer
- MD Breyer
- ME Alfie
- ME Phillips
- ME Phillips
- Michelle Boone
- MJ McKinley
- MN Helms
- N Fujita
- N Marr
- N Marr
- N Marr
- NH Garcia
- P Fernandez-Llama
- P Fernandez-Llama
- P Fernandez-Llama
- P Koulen
- Peter M. T. Deen
- PG Charest
- PI Nedvetsky
- PMT Deen
- R Bouley
- R Bouley
- R Hermosilla
- R Mangoo-Karim
- R Oishi
- R Sandford
- R Sun
- RJ Unwin
- RL Hebert
- RL Hebert
- RL Hebert
- RL Hebert
- RM Edwards
- RM Edwards
- RM Edwards
- RM Hays
- S Gonzalez-Perrett
- S Gouraud
- S Homma
- S Nagao
- S Nielsen
- S Nielsen
- S Nielsen
- S Nielsen
- S Nielsen
- S Puri
- S Takeda
- S Wang
- SC Parnell
- SH Lin
- SM Mulders
- SM Mulders
- SM Nauli
- SP Nadler
- SP Nadler
- SP Nadler
- SZ Li
- T Inoue
- T Katsura
- T Katsura
- T Mochizuki
- T Rieg
- T Yamaguchi
- T Yamaguchi
- T Yamaguchi
- TE Jonassen
- TE Jonassen
- TH Kwon
- TH Kwon
- TP Dousa
- TX Sun
- U Hasler
- US Jeon
- V Henn
- V Ralevic
- V Sauzeau
- VE Torres
- VE Torres
- VH Gattone
- VH Gattone
- W Lu
- W Lu
- W Rosenthal
- W Wang
- WC Putnam
- X Guo
- X Wang
- Y Ando
- Y Ando
- Y Asahina
- Y Cai
- Y Ge
- Y Ge
- Y Ge
- Y Huan
- Y Li
- Y Maeda
- Y Maeda
- Y Matsumura
- Y Noda
- Y Noda
- Y Pan
- Y Sakairi
- Y Wu
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2008
- Field of study
To prevent dehydration, terrestrial animals and humans have developed a sensitive and versatile system to maintain their water homeostasis. In states of hypernatremia or hypovolemia, the antidiuretic hormone vasopressin (AVP) is released from the pituitary and binds its type-2 receptor in renal principal cells. This triggers an intracellular cAMP signaling cascade, which phosphorylates aquaporin-2 (AQP2) and targets the channel to the apical plasma membrane. Driven by an osmotic gradient, pro-urinary water then passes the membrane through AQP2 and leaves the cell on the basolateral side via AQP3 and AQP4 water channels. When water homeostasis is restored, AVP levels decline, and AQP2 is internalized from the plasma membrane, leaving the plasma membrane watertight again. The action of AVP is counterbalanced by several hormones like prostaglandin E2, bradykinin, dopamine, endothelin-1, acetylcholine, epidermal growth factor, and purines. Moreover, AQP2 is strongly involved in the pathophysiology of disorders characterized by renal concentrating defects, as well as conditions associated with severe water retention. This review focuses on our recent increase in understanding of the molecular mechanisms underlying AVP-regulated renal water transport in both health and disease
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells.
- Author
- Aanensen DM
- Abudahab K
- Adams A
- Adams H
- Adeniji K
- Afifi S
- Aggarwal D
- Agranoff D
- Agwuh K
- Ahmad SSY
- Ahmed KA
- Aigrain L
- Ail D
- Alcolea-Medina A
- Aldera EL
- Alegria A
- Alex B
- Alikhan N-F
- Allara E
- Allen S
- Amato R
- Andrikopoulos P
- Angus B
- Angyal A
- Annett T
- Aplin S
- Ariani CV
- Armstrong JA
- Asad H
- Ash A
- Ashfield P
- Ashford F
- Ashish A
- Ashworth M
- Asiimwe IG
- Atkinson D
- Atkinson L
- Attwood SW
- Auckland C
- Aydin A
- Bach B
- Baillie JK
- Baker DJ
- Baker P
- Bakshi S
- Balcazar CE
- Ball J
- Barclay WS
- Bari S
- Barlow G
- Barlow SL
- Barnass S
- Barrett JC
- Barrett N
- Barrow M
- Barton E
- Bashton M
- Bassett AR
- Bassford C
- Basude S
- Batra R
- Baxter C
- Baxter D
- Bayzid N
- Beadsworth M
- Beaver C
- Beckett AH
- Beckwith SM
- Bedford L
- Beer R
- Beggs A
- Bellis KL
- Bernatoniene J
- Berridge J
- Berry C
- Berry L
- Bertolusso B
- Best A
- Best N
- Betteridge E
- Bibby D
- Bicknell K
- Binns D
- Birchley A
- Bird PW
- Bishop C
- Blacow R
- Blakey V
- Blane B
- Bogaert D
- Bolt F
- Bonfield J
- Bonner S
- Bonsall D
- Booth L
- Boswell T
- Bosworth A
- Bothma P
- Bourgeois Y
- Boyd O
- Bradley DT
- Breen C
- Brennan B
- Bresner C
- Breuer J
- Bridgett S
- Brittain-Long R
- Bronner IF
- Brooks E
- Broos A
- Brown JR
- Brown R
- Bucca G
- Buchan SL
- Buck D
- Bull M
- Bullock K
- Bulteel N
- Burden T
- Burns PJ
- Burtenshaw A
- Burton-Fanning S
- Byaruhanga T
- Byott M
- Campbell S
- Carabelli AM
- Cargill JS
- Carlile M
- Carlucci N
- Carracedo AD
- Carson G
- Caruth V
- Carvalho SF
- Casey A
- Cass E
- Castigador A
- Catalan J
- Catterall BWA
- Chadwick D
- Chadwick D
- Chalker V
- Chaloner NJ
- Chambler D
- Chand M
- Chand M
- Chappell JG
- Charalampous T
- Chatterton W
- Chaudhry Y
- Chechi K
- Chee N
- Child J
- Chukkambotla S
- Churcher CM
- Clark G
- Clark JJ
- Clark T
- Clarke EA
- Clarke P
- Clohisey S
- Cogger BJ
- Cole K
- Cole S
- Cole S
- Collini P
- Collins J
- Colquhoun R
- Connor M
- Connor TR
- Cook KF
- Cooke GS
- Coombes J
- Cooper L
- Corden S
- Cormie C
- Correia GDS
- Cortes N
- Cosgrove C
- Cotic M
- Cotton S
- Cottrell S
- Coupland L
- Cox A
- Cox H
- Cox M
- Craine N
- Crawford L
- Cross A
- Crown MR
- Crudgington D
- Cumley N
- Cupitt J
- Curran MD
- Curran T
- Cutino-Moguel M-T
- da Silva Filipe A
- da Silva Filipe A
- Dabrera G
- Dalton J
- Darby AC
- Dark P
- Davidson RK
- Davies A
- Davies RM
- Davis C
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- Dawson C
- de Angelis D
- De Lacy E
- de Oliveira Martins L
- de Silva TI
- Debebe J
- Denton-Smith R
- Dervisevic S
- Dervisevic S
- Dewar R
- Dey J
- Dias J
- Dincarslan O
- Dobie D
- Docherty AB
- Donegan C
- Dong D
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- Donnison P
- Donohue C
- Dorman MJ
- Douthwaite S
- Downing F
- Driscoll M
- Drummond A
- du Plessis L
- Duckworth N
- Dumas M-E
- Dunachie S
- Dunn C
- Dunning J
- DuRand I
- Durham J
- Dushianthan A
- Dyer P
- Dyer T
- Eastick K
- Easton LJ
- Eccles R
- Edgeworth J
- Edwards S
- El Bouzidi K
- Eldirdiri S
- Ellaby N
- Elliott A
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- Eltringham G
- Ensell L
- Erkiert MJ
- Essex S
- Evans A
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- Everson W
- Eziefula C
- Fairley DJ
- Fallon K
- Fanaie A
- Farr BW
- Fearn C
- Fegan C
- Feltwell T
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- Fisher LWS
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- Foulkes BH
- Foulser L
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- Frampton D
- Francois S
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- Georgana I
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- Girgis ST
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- Gkrania-Klotsas E
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- Goldsmith A
- Goldstein EJ
- Golubchik T
- Gomes AN
- Gonçalves S
- Goodfellow IG
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- Gourtovaia M
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- Holden MTG
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- Impey R
- Irish-Tavares D
- Iturriza-Gomara M
- Izuagbe R
- Jackson B
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- Jackson DK
- Jackson KA
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- Jahun AS
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- Kaliappan A
- Kasipandian V
- Kay GL
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- Keating S
- Keatley J-P
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- Kenyon A
- Kermack LM
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- Kerslake I
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- Koduri G
- Koshy C
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- Koukorava C
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- Lefteri D
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- Lensing SV
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- Lillie PJ
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- Lindsey BB
- Linnett V
- Lister MM
- Little J
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- Loveson KF
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- Lucaci AO
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- Mack A
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- Maclean A
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- Mahanama AIK
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- Moll RJ
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- Monahan IM
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- Papakonstantinou D
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- Publication venue
- iScience
- Publication date
- 01/01/2021
- Field of study
We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of recognition by epitope-specific T cells assessed by IFN-γ and cytotoxic killing assays. Complete loss of T cell responsiveness was seen due to Q213K in the A∗01:01-restricted CD8+ ORF3a epitope FTSDYYQLY207-215; due to P13L, P13S, and P13T in the B∗27:05-restricted CD8+ nucleocapsid epitope QRNAPRITF9-17; and due to T362I and P365S in the A∗03:01/A∗11:01-restricted CD8+ nucleocapsid epitope KTFPPTEPK361-369. CD8+ T cell lines unable to recognize variant epitopes have diverse T cell receptor repertoires. These data demonstrate the potential for T cell evasion and highlight the need for ongoing surveillance for variants capable of escaping T cell as well as humoral immunity.This work is supported by the UK Medical Research Council (MRC); Chinese Academy of Medical Sciences(CAMS) Innovation Fund for Medical Sciences (CIFMS), China; National Institute for Health Research (NIHR)Oxford Biomedical Research Centre, and UK Researchand Innovation (UKRI)/NIHR through the UK Coro-navirus Immunology Consortium (UK-CIC). Sequencing of SARS-CoV-2 samples and collation of data wasundertaken by the COG-UK CONSORTIUM. COG-UK is supported by funding from the Medical ResearchCouncil (MRC) part of UK Research & Innovation (UKRI),the National Institute of Health Research (NIHR),and Genome Research Limited, operating as the Wellcome Sanger Institute. T.I.d.S. is supported by a Well-come Trust Intermediate Clinical Fellowship (110058/Z/15/Z). L.T. is supported by the Wellcome Trust(grant number 205228/Z/16/Z) and by theUniversity of Liverpool Centre for Excellence in Infectious DiseaseResearch (CEIDR). S.D. is funded by an NIHR GlobalResearch Professorship (NIHR300791). L.T. and S.C.M.are also supported by the U.S. Food and Drug Administration Medical Countermeasures Initiative contract75F40120C00085 and the National Institute for Health Research Health Protection Research Unit (HPRU) inEmerging and Zoonotic Infections (NIHR200907) at University of Liverpool inpartnership with Public HealthEngland (PHE), in collaboration with Liverpool School of Tropical Medicine and the University of Oxford.L.T. is based at the University of Liverpool. M.D.P. is funded by the NIHR Sheffield Biomedical ResearchCentre (BRC – IS-BRC-1215-20017). ISARIC4C is supported by the MRC (grant no MC_PC_19059). J.C.K.is a Wellcome Investigator (WT204969/Z/16/Z) and supported by NIHR Oxford Biomedical Research Centreand CIFMS. The views expressed are those of the authors and not necessarily those of the NIHR or MRC
ICAR: endoscopic skull‐base surgery
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- Wigand ME
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- Yilmazlar S
- Yin ZZ
- Yin ZZ
- Yiotakis I
- Yonezawa K
- Yoo F
- Yoshida E
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- Youssef AS
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- Zanation AM
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- Publication venue
- Publication date
- 01/07/2019
- Field of study
n/
Carbon balance for different management practices for fast growing tree species planted on former pastureland in southern Europe: a case study using the CO2Fix model
- Author
- A Merino
- A Repo
- AE Lugo
- Agustín Merino
- AL Cowie
- AP O’Grady
- B Lemma
- BA Olsson
- BH Jong de
- BR Parresol
- C Jourdan
- C Pérez-Cruzado
- C Pérez-Cruzado
- C Pérez-Cruzado
- C Pérez-Cruzado
- César Pérez-Cruzado
- DP Rasse
- DW Johnson
- DW Johnson
- DW Johnson
- E Alvarez
- EG Jobbágy
- F Castedo-Dorado
- F Castedo-Dorado
- F Holzleitner
- F Solla-Gullón
- G Scarascia-Mugnozza
- GJ Nabuurs
- GJ Nabuurs
- GJ Nabuurs
- GMJ Mohren
- Godefridus M. J. Mohren
- GR Blake
- H Böttcher
- HA Wit de
- HS Helmisaari
- I Profft
- J Brañas
- J Liski
- J Matala
- J McKechnie
- JD Knoepp
- JJ Landsberg
- KG Mattson
- KI Paul
- L Nutto
- M Aguiló
- M Kaul
- M Lindner
- M Mund
- MA Balboa-Murias
- MD Korzukhin
- ME Harmon
- MJ Swift
- OQ Hendrickson
- OR Masera
- PJ Sands
- PJ Smethurst
- R Jandl
- R Lal
- R Lal
- R Rodríguez
- R Rodríguez
- RA Gill
- Roque Rodríguez-Soalleiro
- S Monni
- S Pérez
- S Pérez
- SC Resh
- T Groen
- T Karjalainen
- T Karjalainen
- T Karjalainen
- T Palosuo
- T Palosuo
- T Räisänen
- TA Black
- U Diéguez-Aranda
- UNFCCC
- WM Post
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Long-Baseline Neutrino Facility (LBNF) and Deep Underground Neutrino Experiment (DUNE) Conceptual Design Report Volume 1: The LBNF and DUNE Projects
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- Acciarri R
- Acero MA
- Adamowski M
- Adams C
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- Adamson P
- Adhikari S
- Ahmad Z
- Albright CH
- Alion T
- Amador E
- Anderson J
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- Andreopoulos C
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- Anghel I
- Anjos JD
- Ankowski A
- Antonello M
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- Aristizabal D
- Arrieta-Diaz E
- Aryal K
- Asaadi J
- Asner D
- Athar MS
- Auger M
- Aurisano A
- Aushev V
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- Baibussinov B
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- Baller B
- Ballett P
- Bambah B
- Bansal M
- Bansal S
- Barker GJ
- Barletta WA
- Barr G
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- Bartoszek L
- Bashyal A
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- Bay F
- Beacom J
- Behera BR
- Bellettini G
- Bellini V
- Beltramello O
- Benetti PA
- Bercellie A
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- Berns H
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- Bertolucci S
- Bhandari B
- Bhatnagar V
- Bhuyan B
- Bian J
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- Bishai M
- Blackburn T
- Blake A
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- Blaufuss E
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- Boffelli F
- Boissevain J
- Bolognesi S
- Bolton T
- Bonesini M
- Boone T
- Booth C
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- Bourguille B
- Boyd SB
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- Brandt A
- Bremer J
- Brice S
- Bromberg C
- Brooijmans G
- Brown G
- Brown R
- Brunetti G
- Bu X
- Buchanan N
- Budd H
- Bugg B
- Calafiura P
- Calligarich E
- Calvo E
- Camilleri L
- Campanelli M
- Cantini C
- Carls B
- Carr R
- Cascella M
- Castromonte C
- CatanoMur E
- Cavanna F
- Centro S
- CerveraVillanueva A
- Chandratre VB
- Chatterjee A
- Chattopadhyay S
- Chattopadhyay S
- Chaussard L
- Chembra S
- Chen H
- Chen K
- Chen M
- Cherdack D
- Chi C
- Childress S
- Choubey S
- Choudhary BC
- Christodoulou G
- Christofferson C
- Church E
- Cianci D
- Cline D
- Coan T
- Cocco A
- Coelho J
- Cole P
- Collin G
- Conrad JM
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- Corey R
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- Cranshaw J
- Crivelli P
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- Curioni A
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- deJong JK
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- Densham C
- Dharmapalan R
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- Dolph J
- Drake G
- Duchesneau D
- Duvernois M
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- Eberly B
- Edgecock R
- Edmunds D
- Elliott S
- Elnimr M
- Emery S
- Endress E
- Eno S
- Ereditato A
- Escobar CO
- Evans J
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- Verdugo A
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- Vieira TV
- Vignoli C
- Vilela C
- Viren B
- Vrba T
- Wachala T
- Wahl D
- Wallbank M
- Walsh N
- Wang B
- Wang H
- Wang L
- Wang T
- Warburton TK
- Warner D
- Wascko M
- Waters D
- Watson TB
- Weber A
- Weber M
- Wei W
- Weinstein A
- Wells D
- Wenman D
- Wetstein M
- White A
- Whitehead L
- Whittington D
- Wilking M
- Willhite J
- Wilson P
- Wilson RJ
- Winslow L
- Wittich P
- Wojcicki S
- Wong HH
- Wood K
- Worcester E
- Worcester M
- Wu S
- Xin T
- Yanagisawa C
- Yang S
- Yang T
- Yarritu K
- Ye J
- Yeh M
- Yershov N
- Yonehara K
- Yu B
- Yu J
- Zalesak J
- Zalewska A
- Zamorano B
- Zang L
- Zani A
- Zani A
- Zavala G
- Zeller G
- Zhang C
- Zhang C
- Zimmerman ED
- Zito M
- Zwaska R
- Publication venue
- Publication date
- 01/01/2016
- Field of study
This document presents the Conceptual Design Report (CDR) put forward by an international neutrino community to pursue the Deep Underground Neutrino Experiment at the Long-Baseline Neutrino Facility (LBNF/DUNE), a groundbreaking science experiment for long-baseline neutrino oscillation studies and for neutrino astrophysics and nucleon decay searches. The DUNE far detector will be a very large modular liquid argon time-projection chamber (LArTPC) located deep underground, coupled to the LBNF multi-megawatt wide-band neutrino beam. DUNE will also have a high-resolution and high-precision near detector
The Single-Phase ProtoDUNE Technical Design Report
- Author
- Abi B
- Acciarri R
- Acero MA
- Adamowski M
- Adams C
- Adams DL
- Adamson P
- Adinolfi M
- Ahmad Z
- Albright CH
- Alion T
- Anderson J
- Anderson K
- Andreopoulos C
- Andrews MP
- Andrews RA
- Anjos J dos
- Ankowski A
- Anthony J
- Antonello M
- Ariga A
- Ariga T
- Asaadi J
- Ascencio M
- Asner DM
- Athar MS
- Auger M
- Aurisano A
- Aushev V
- Autiero D
- Azfar F
- Back HO
- Back JJ
- Backhouse C
- Bai X
- Baird M
- Balantekin AB
- Balasubramanian S
- Baller B
- Ballett P
- Bambah B
- Band H
- Bansal M
- Bansal S
- Barker GJ
- Barr G
- Barros N
- Bashyal A
- Bass M
- Bautista G Diaz
- Bay F
- Bazo JL
- Beacom JF
- Behera BR
- Bellettini G
- Bellini V
- Beltramello O
- Benekos N
- Benetti PA
- Bercellie A
- Berg R Van
- Berman E
- Berns H
- Bernstein R
- Bertolucci S
- Bhatnagar V
- Bhuyan B
- Bian J
- Biery K
- Bishai M
- Bitadze A
- Blackburn T
- Blake A
- Blaszczyk FDM
- Blaufuss E
- Blazey GC
- Blennow M
- Blucher E
- Bocean V
- Boffelli F
- Boissevain J
- Bolognesi S
- Bolton T
- Bonesini M
- Bonis I De
- Boone T
- Booth C
- Bordoni S
- Bour P
- Bourguille B
- Boyd SB
- Boyden D
- Brailsford D
- Brandt A
- Bremer J
- Brice SJ
- Bromberg C
- Brooijmans G
- Brown G
- Brunetti G
- Buchanan N
- Budd H
- Bueno L Molina
- Cadenas JJ Gomez
- Caicedo DA Martinez
- Calafiura P
- Calatayud A
- Calligarich E
- Calvo E
- Camilleri L
- Campanelli M
- Campo A Olivares Del
- Cantini C
- Carls B
- Cascella M
- Catano-Mur E
- Cavaili-Sforza M
- Cavanna F
- Centro S
- Cervi T
- Chalifour M
- Chappuis A
- Chatterjee A
- Chattopadhyay S
- Chattopadhyay S
- Chaussard L
- Chembra S
- Chen H
- Chen M
- Cherdack D
- Chi C
- Childress S
- Choubey S
- Choudhary BC
- Christodoulou G
- Christofferson C
- Church E
- Coan TE
- Cocco A
- Cole P
- Collin G
- Conrad JM
- Convery M
- Corey R
- Corwin L
- Crespo-Anadón JI
- Crivelli P
- Cronin-Hennessy D
- Crowley C
- Curioni A
- Cussans D
- Dale D
- Davenne T
- Davies GS
- Davies J
- Dawson J
- De K
- Decowski MP
- Dedin-Neto P
- Delbart A
- Delepine D
- Delgado M
- Demuth D
- Dennis S
- Densham C
- Dharmapalan R
- Dhingra N
- Diamantopoulou M
- Diaz E Arrieta
- Diaz JS
- Ding P
- Diwan M
- Djurcic Z
- Dolinski MJ
- Drake G
- Duchesneau D
- Dutta D
- Duvernois M
- Duyang H
- Dwyer DA
- Dye S
- Dyshkant AS
- Dytman S
- Eads M
- Eberly B
- Edmunds D
- Elliott S
- Ellsworth WM
- Elnimr M
- Emery S
- Eno S
- Ereditato A
- Escobar CO
- Evans JJ
- Fahey K
- Falcone A
- Falk L
- Farbin A
- Farnese C
- Farzan Y
- Fasoli M
- Fava A
- Felix J
- Fernandez A Aranda
- Fernandez-Martinez E
- Fields L
- Filthaut F
- Finch A
- Fitton M
- Fleming BT
- Forest T
- Fowler J
- Fox W
- Freeman J
- Freestone J
- Friant D
- Fried J
- Friedland A
- Fuess S
- Fujikawa B
- Gago A
- Gallagher H
- Galvin S
- Galymov S
- Gamble T
- Gandhi R
- Gao S
- Garcia-Gamez D
- Gardiner S
- Gastler D
- Gendotti A
- Gibin D
- Gil-Botella I
- Gill R
- Giri AK
- Goeldi D
- Gold M
- Gollapinni S
- Gomes RA
- Goodman MC
- Gorbunov D
- Goswami S
- Gouvea A De
- Graf N
- Graf N
- Graham M
- Gramelini E
- Gran R
- Grant C
- Grant N
- Greco V
- Greenlee H
- Greenler L
- Groh M
- Grzelak K
- Guardincerri E
- Guarino V
- Guedes GP
- Guenette R
- Guglielmi A
- Guthikonda KK
- Guzzo MM
- Habig AT
- Hackenburg A
- Hackenburg RW
- Hadavand H
- Haenni R
- Hahn A
- Haigh MD
- Haines T
- Hamernik T
- Hamilton P
- Handler T
- Hans S
- Harris D
- Hartnell J
- Hasegawa T
- Hatcher R
- Hatzikoutelis A
- Hays S
- Hazen E
- Headley M
- Heavey A
- Heeger KM
- Heise J
- Hennessy K
- Henry S
- Hernandez-Garcia J
- Hewes J
- Higuera A
- Hill T
- Himmel A
- Holanda PC de
- Holin A
- Hoppe EW
- Horikawa S
- Horton-Smith G
- Hostert M
- Hourlier A
- Howard B
- Howell J
- Hugon J
- Hurh P
- Huston J
- Hylen J
- Insler J
- Introzzi G
- Ioannisian A
- Izmaylov A
- Jaffe DE
- James C
- James E
- Jang CH
- Jediny F
- Jen C
- Jhingan A
- Jiménez S
- Johnson M
- Johnson R
- Johnstone J
- Jong P De
- Joshi J
- Jostlein H
- Jung CK
- Junk T
- Kaboth A
- Kadenko I
- Kamyshkov Y
- Karagiorgi G
- Karasavvas D
- Karyotakis Y
- Kaur P
- Kayser B
- Kazaryan N
- Kearns E
- Keener PT
- Kemp E
- Kendziora C
- Ketchum W
- Kettell SH
- Khabibullin M
- Khotjantsev A
- Kirby B
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- Ko YJ
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- Kocaman B
- Koerner LW
- Kohn S
- Koizumi G
- Kopylov A
- Kordosky M
- Kormos L
- Kose U
- Kostelecký VA
- Kramer M
- Kreslo I
- Kriesel K
- Kropp W
- Kudenko Y
- Kudryavtsev VA
- Kulagin S
- Kumar A
- Kumar J
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- Kutter T
- Lande K
- Lane C
- Lang K
- Langford T
- Lanni F
- Laundrie A
- Le T
- Learned J
- Lebrun P
- Lee D
- Lee WM
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- Link J
- Liptak Z
- Lissauer D
- Littenberg L
- Littlejohn BR
- Liu J
- Liu Q
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- Lockwitz S
- Lockyer N
- Loew T
- Lokajicek M
- LoMonaco L
- Long K
- Loo K
- Lopez JP
- Lorca D
- LoSecco JM
- Louis W
- Luethi M
- Luk KB
- Lundin T
- Luo X
- Lurgio P De
- Lux T
- Lykken J
- Maalampi J
- Machado AA
- Macias CT
- Macier JR
- MacLellan R
- Magill S
- Mahler G
- Mahn K
- Malek M
- Mammoliti F
- Mandal SK
- Mandodi S
- Manly S
- Mann A
- Marchionni A
- Marciano W
- Marfatia D
- Mariani C
- Maricic J
- Marino AD
- Marshak M
- Marshall CM
- Marshall J
- Marteau J
- Martin-Albo J
- Masud M
- Matsuno S
- Matthews J
- Mauger C
- Mavrokoridis K
- Mazza R
- Mazzacane A
- Mazzucato E
- McCauley N
- McCluskey E
- McConkey N
- McDonald KT
- McFarland KS
- McGivern C
- McGowan AM
- McGrew C
- McGuinness SR
- McKeown R
- McNulty D
- McTaggart R
- Mefodiev A
- Mehta P
- Mei D
- Mena O
- Menary S
- Mendez DP
- Mendez H
- Menegolli A
- Menendez P Fernandez
- Meng G
- Messier M
- Metcalf W
- Mewes M
- Meyer H
- Miao T
- Milincic R
- Miller W
- Mills G
- Mineev O
- Miranda OG
- Mishra CS
- Mishra SR
- Mitrica B
- Mladenov D
- Mocioiu I
- Moffat K
- Mohanta R
- Mokhov N
- Monarca J Barranco
- Montanari C
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- Moon J
- Mooney M
- Moore CD
- Morgan B
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- Mossey C
- Motta H da
- Moura CA
- Mousseau J
- Mualem L
- Muether M
- Mufson S
- Murphy S
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- Nakajima Y
- Naples D
- Navarro J
- Navas-Nicolás D
- Nelson J
- Nessi M
- Newbold D
- Newcomer M
- Nguyen KTT
- Nichol R
- Nicholls TC
- Niner E
- Norman A
- Norris B
- Novakova P
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- Nowak E
- Nowak J
- Nunes MS
- O'Keeffe H
- Oliveira MA Leigui de
- Oliveira R
- Olivier A
- Onishchuk Y
- Ovsjannikova T
- Pakvasa S
- Palamara O
- Paley J
- Palomares C
- Pantic E
- Paolone V
- Papadimitriou V
- Paramesvaran S
- Park J
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- Pawloski G
- Payne D
- Peeters SJM
- Pennacchio E
- Perdue GN
- Peres OLG
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- Perkin JD
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- Petukhov A
- Picchi P
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- Plunkett R
- Poling R
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- Potekhin M
- Potenza R
- Potukuchi B
- Poudel S
- Pozimski J
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- Przewlocki P
- Pumulo N
- Pushka D
- Qian X
- Raaf JL
- Raboanary R
- Radeka V
- Rademacker J
- Radics B
- Radovic A
- Rakhno I
- Rakotondramanana HT
- Rakotondravohitra L
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- Rameika R
- Ramsey J
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- Raselli G
- Ratoff P
- Rebel B
- Regenfus C
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- Reitzner SD
- Remoto A
- Renshaw A
- Rescia S
- Rice L
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- Riesselmann K
- Rivera D
- Robinson M
- Rochester L
- Rodrigues OB
- Rodrigues P
- Roe B
- Rohr C Rudolph von
- Roser RM
- Ross-Lonergan M
- Rossella M
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- Rubbia A
- Rubbia C
- Rucinski R
- Russell B
- Ruterbories D
- Saakyan R
- Sachdev K
- Sahu N
- Sala P
- Samios N
- Sanchez F
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- Sands WR
- Sankar S Uma
- Santana S
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- Santos LM
- Santucci G
- Saoulidou N
- Savage G
- Scaramelli A
- Scarpelli A
- Schaffer T
- Schellman H
- Schlabach P
- Schmitz D
- Schneps J
- Scholberg K
- Schukraft A
- Segreto E
- Sehrawat S
- Sepulveda-Quiroz JA
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- Snopok P
- Sobczyk J
- Sobel H
- Soderberg M
- Solomey N
- Sondheim W
- Sorel M
- Sousa A
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- Spanu M
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- Spooner NJC
- Stancari M
- Stefan D
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- Steiner HM
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- Stoica S
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- Strait M
- Strauss T
- Striganov S
- Sulej R
- Sullivan G
- Sun Y
- Suter L
- Sutera CM
- Svoboda R
- Szczerbinska B
- Szelc AM
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- Talaga R
- Tariq S
- Tatar E
- Tayloe R
- Terao K
- Thiesse M
- Thompson LF
- Thomson M
- Thorn C
- Thorpe M
- Tian X
- Tiedt D
- Timm SC
- Todd J
- Tonazzo A
- Tope T
- Torres FR
- Torti M
- Tortola M
- Tortorici F
- Toups M
- Touramanis C
- Trevor J
- Tripathi M
- Tropin I
- Trzaska WH
- Tsai Y
- Tsang KV
- Tsaris A
- Tsenov R
- Tufanli S
- Tull C
- Turner J
- Tzanov M
- Tziaferi E
- Uchida Y
- Urheim J
- Usher T
- Vagins MR
- Vahle P
- Valdiviesso GA
- Valerio L
- Vallari Z
- Valle J
- Varanini F
- Varner G
- Vasseur G
- Vaziri K
- Velev G
- Ventura S
- Verdugo A
- Vermeulen MA
- Vernon E
- Viant T
- Vieira TV
- Vignoli C
- Vihonen S
- Vilela C
- Villanueva A Cervera
- Viren B
- Vokac P
- Vrba T
- Vries JJ de
- Wachala T
- Wahl D
- Wallbank M
- Wang B
- Wang H
- Wang T
- Warburton TK
- Warner D
- Wascko M
- Water R Van de
- Waters D
- Weber A
- Weber M
- Wei W
- Weinstein A
- Wenman D
- Wetstein M
- White A
- Whitehead LH
- Whittington D
- Wilking MJ
- Willhite J
- Wilson P
- Wilson RJ
- Wittich P
- Wolcott J
- Wong HH
- Wongjirad T
- Wood K
- Wood LS
- Worcester E
- Worcester M
- Wu S
- Xu W
- Yanagisawa C
- Yang S
- Yang T
- Ye J
- Yeh M
- Yershov N
- Yonehara K
- Yu B
- Yu J
- Zalesak J
- Zambelli L
- Zamorano B
- Zang L
- Zani A
- Zaremba K
- Zeller GP
- Zhang C
- Zhang C
- Zhou Y
- Zimmerman ED
- Zito M
- Zuklin J
- Zutshi V
- Zwaska R
- Publication venue
- Publication date
- 01/01/2017
- Field of study
ProtoDUNE-SP is the single-phase DUNE Far Detector prototype that is under construction and will be operated at the CERN Neutrino Platform (NP) starting in 2018. ProtoDUNE-SP, a crucial part of the DUNE effort towards the construction of the first DUNE 10-kt fiducial mass far detector module (17 kt total LAr mass), is a significant experiment in its own right. With a total liquid argon (LAr) mass of 0.77 kt, it represents the largest monolithic single-phase LArTPC detector to be built to date. It's technical design is given in this report
Long-Baseline Neutrino Facility (LBNF) and Deep Underground Neutrino Experiment (DUNE) Conceptual Design Report, Volume 4 The DUNE Detectors at LBNF
- Author
- Acciarri R
- Acero MA
- Adamowski M
- Adams C
- Adams DL
- Adamson P
- Adhikari S
- Ahmad Z
- Albright CH
- Alion T
- Amador E
- Anderson J
- Anderson K
- Andreopoulos C
- Andrews M
- Andrews R
- Anghel I
- Anjos JD
- Ankowski A
- Antonello M
- ArandaFernandez A
- Ariga A
- Ariga T
- Aristizabal D
- Arrieta-Diaz E
- Aryal K
- Asaadi J
- Asner D
- Athar MS
- Auger M
- Aurisano A
- Aushev V
- Autiero D
- Avila M
- Back JJ
- Bai X
- Baibussinov B
- Baird M
- Balantekin AB
- Baller B
- Ballett P
- Bambah B
- Bansal M
- Bansal S
- Barker GJ
- Barletta WA
- Barr G
- Barros N
- Bartoszek L
- Bashyal A
- Bass M
- Bay F
- Beacom J
- Behera BR
- Bellettini G
- Bellini V
- Beltramello O
- Benetti PA
- Bercellie A
- Bergevin M
- Berman E
- Berns H
- Bernstein R
- Bertolucci S
- Bhandari B
- Bhatnagar V
- Bhuyan B
- Bian J
- Biery K
- Bishai M
- Blackburn T
- Blake A
- Blaszczyk FDM
- Blaufuss E
- Bleakley B
- Blucher E
- Bocean V
- Boffelli F
- Boissevain J
- Bolognesi S
- Bolton T
- Bonesini M
- Boone T
- Booth C
- Bordoni S
- Borysova M
- Bourguille B
- Boyd SB
- Brailsford D
- Brandt A
- Bremer J
- Brice S
- Bromberg C
- Brooijmans G
- Brown G
- Brown R
- Brunetti G
- Bu X
- Buchanan N
- Budd H
- Bugg B
- Calafiura P
- Calligarich E
- Calvo E
- Camilleri L
- Campanelli M
- Cantini C
- Carls B
- Carr R
- Cascella M
- Castromonte C
- CatanoMur E
- Cavanna F
- Centro S
- CerveraVillanueva A
- Chandratre VB
- Chatterjee A
- Chattopadhyay S
- Chattopadhyay S
- Chaussard L
- Chembra S
- Chen H
- Chen K
- Chen M
- Cherdack D
- Chi C
- Childress S
- Choubey S
- Choudhary BC
- Christodoulou G
- Christofferson C
- Church E
- Cianci D
- Cline D
- Coan T
- Cocco A
- Coelho J
- Cole P
- Collin G
- Conrad JM
- Convery M
- Corey R
- Corwin L
- Cranshaw J
- Crivelli P
- Cronin-Hennessy D
- Curioni A
- Cushing J
- Dale D
- Das SR
- Davenne T
- Davies GS
- Davies J
- Dawson J
- De K
- Decowski M
- deGouvea A
- deJong JK
- deJong P
- Delbart A
- DeLurgio P
- Densham C
- Dharmapalan R
- Dhingra N
- Diamantopoulou M
- Diaz JS
- DiazBautista G
- DiLuise S
- Diwan M
- Djurcic Z
- Dolph J
- Drake G
- Duchesneau D
- Duvernois M
- Duyang H
- Dwyer DA
- Dye S
- Dytman S
- Eberly B
- Edgecock R
- Edmunds D
- Elliott S
- Elnimr M
- Emery S
- Endress E
- Eno S
- Ereditato A
- Escobar CO
- Evans J
- Falcone A
- Falk L
- Farbin A
- Farnese C
- Farzan Y
- Fava A
- Favilli L
- Felde J
- Felix J
- Fernandes S
- Fields L
- Finch A
- Fitton M
- Fleming B
- Forest T
- Fowler J
- Fox W
- Fried J
- Friedland A
- Fuess S
- Fujikawa B
- Gago A
- Gallagher H
- Galymov S
- Gamble T
- Gandhi R
- Garcia-Gamez D
- Gardiner S
- Garvey G
- Gehman VM
- Gendotti A
- Geronimo GD
- Ghag C
- Ghoshal P
- Gibin D
- Gil-Botella I
- Gill R
- Girardelli D
- Giri A
- Glavin S
- Goeldi D
- Golapinni S
- Gold M
- Gomes RA
- GomezCadenas JJ
- Goodman MC
- Gorbunov D
- Goswami S
- Graf N
- Graf N
- Graham M
- Gramelini E
- Gran R
- Grant C
- Grant N
- Greco V
- Greenlee H
- Greenler L
- Greenley C
- Groh M
- Grullon S
- Grundy T
- Grzelak K
- Guardincerri E
- Guarino V
- Guarnaccia E
- Guedes GP
- Guenette R
- Guglielmi A
- Habig AT
- Hackenburg A
- Hackenburg RW
- Hadavand H
- Haenni R
- Hahn A
- Haigh MD
- Haines T
- Hamernik T
- Handler T
- Hans S
- Harris D
- Hartnell J
- Hasegawa T
- Hatcher R
- Hatzikoutelis A
- Hays S
- Hazen E
- Headley M
- Heavey A
- Heeger K
- Heise J
- Hennessy K
- Hewes J
- Higuera A
- Hill T
- Himmel A
- Hogan M
- Holanda P
- Holin A
- Honey W
- Horikawa S
- Horton-Smith G
- Howard B
- Howell J
- Hurh P
- Huston J
- Hylen J
- Imlay R
- Insler J
- Introzzi G
- Ioanisyan D
- Ioannisian A
- Iwamoto K
- Izmaylov A
- Jackson C
- Jaffe DE
- James C
- James E
- Jediny F
- Jen C
- Jhingan A
- Jiménez S
- Jo JH
- Johnson M
- Johnson R
- Johnstone J
- Jones BJ
- Joshi J
- Jostlein H
- Jung CK
- Junk T
- Kaboth A
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- Publication venue
- Publication date
- Field of study
A description of the proposed detector(s) for DUNE at LBN
The Single-Phase ProtoDUNE Technical Design Report
- Author
- Abi B
- Acciarri R
- Acero MA
- Adamowski M
- Adams C
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- Kamyshkov Y
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- Karasavvas D
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- Kaur P
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- Kazaryan N
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- Keener PT
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- Khabibullin M
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- Kirby B
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- Kobilarcik T
- Kocaman B
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- Koizumi G
- Kopylov A
- Kordosky M
- Kormos L
- Kose U
- Kostelecký VA
- Kramer M
- Kreslo I
- Kriesel K
- Kropp W
- Kudenko Y
- Kudryavtsev VA
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- Liptak Z
- Lissauer D
- Littenberg L
- Littlejohn BR
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- Liu Q
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- Lockyer N
- Loew T
- Lokajicek M
- LoMonaco L
- Long K
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- Maricic J
- Marino AD
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- Marshall CM
- Marshall J
- Marteau J
- Martin-Albo J
- Masud M
- Matsuno S
- Matthews J
- Mauger C
- Mavrokoridis K
- Mayilyan D
- Mazza R
- Mazzacane A
- Mazzucato E
- McCauley N
- McCluskey E
- McConkey N
- McDonald KT
- McFarland KS
- McGivern C
- McGowan AM
- McGrew C
- McGuinness SR
- McKeown R
- McNulty D
- McTaggart R
- Mefodiev A
- Mehta P
- Mei D
- Mena O
- Menary S
- Mendez DP
- Mendez H
- Menegolli A
- Meng G
- Messier M
- Metcalf W
- Mewes M
- Meyer H
- Miao T
- Milincic R
- Miller W
- Mills G
- Mineev O
- Miranda OG
- Mishra CS
- Mishra SR
- Mitrica B
- Mladenov D
- Mocioiu I
- Moffat K
- Mohanta R
- Mokhov N
- Monarca JB
- Montanari C
- Montanari D
- Moon J
- Mooney M
- Moore CD
- Morgan B
- Morris C
- Morse W
- Mossey C
- Motta HD
- Moura CA
- Mousseau J
- Mualem L
- Muether M
- Mufson S
- Murphy S
- Musser J
- Nakajima Y
- Naples D
- Navarro J
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- Nelson J
- Nessi M
- Newbold D
- Newcomer M
- Nguyen KTT
- Nichol R
- Nicholls TC
- Niner E
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- Norris B
- Novakova P
- Novella P
- Nowak E
- Nowak J
- Nunes MS
- O'Keeffe H
- Oliveira MALD
- Oliveira R
- Olivier A
- Onishchuk Y
- Ovsjannikova T
- Pakvasa S
- Palamara O
- Paley J
- Palomares C
- Pantic E
- Paolone V
- Papadimitriou V
- Paramesvaran S
- Park J
- Parke S
- Parsa Z
- Pascoli S
- Pasternak J
- Pater J
- Patterson RB
- Patton SJ
- Patzak T
- Paulos B
- Paulucci L
- Pavlovic Z
- Pawloski G
- Payne D
- Peeters SJM
- Pennacchio E
- Perdue GN
- Peres OLG
- Periale L
- Perkin JD
- Petridis K
- Petti R
- Petukhov A
- Picchi P
- Pietropaolo F
- Plonski P
- Plunkett R
- Poling R
- Popovic M
- Pordes S
- Potekhin M
- Potenza R
- Potukuchi B
- Poudel S
- Pozimski J
- Prats JC
- Prokofiev O
- Pruthi N
- Przewlocki P
- Pumulo N
- Pushka D
- Qian X
- Raaf JL
- Raboanary R
- Radeka V
- Rademacker J
- Radics B
- Radovic A
- Rakhno I
- Rakotondramanana HT
- Rakotondravohitra L
- Ramachers YA
- Rameika R
- Ramsey J
- Rappoldi A
- Raselli G
- Ratoff P
- Rebel B
- Regenfus C
- Reichenbacher J
- Reitzner SD
- Remoto A
- Renshaw A
- Rescia S
- Rice L
- Rielage K
- Riesselmann K
- Rivera D
- Robinson M
- Rochester L
- Rodrigues OB
- Rodrigues P
- Roe B
- Rohr CRV
- Roser RM
- Ross-Lonergan M
- Rossella M
- Roy S
- Rubbia A
- Rubbia C
- Rucinski R
- Russell B
- Ruterbories D
- Saakyan R
- Sachdev K
- Sahu N
- Sala P
- Samios N
- Sanchez F
- Sanchez LE
- Sanchez MC
- Sands WR
- Sankar SU
- Santana S
- Santorelli R
- Santos LM
- Santucci G
- Saoulidou N
- Savage G
- Scaramelli A
- Scarpelli A
- Schaffer T
- Schellman H
- Schlabach P
- Schmitz D
- Schneps J
- Scholberg K
- Schukraft A
- Segreto E
- Sehrawat S
- Sepulveda-Quiroz JA
- Sergiampietri F
- Sexton K
- Sexton-Kennedy L
- Shaevitz MH
- Shahsavarani S
- Shanahan P
- Sharma R
- Sharma RK
- Shaw T
- Shooltz D
- Shrock R
- Simos N
- Sinclair J
- Sinev G
- Singh I
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- Singh V
- Sippach FW
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- Smolik J
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- Snider E
- Snopok P
- Sobczyk J
- Sobel H
- Soderberg M
- Solomey N
- Sondheim W
- Sorel M
- Sousa A
- Soustruznik K
- Spanu M
- Spitz J
- Spooner NJC
- Stancari M
- Stefan D
- Stefanik A
- Steiner HM
- Stewart J
- Stock J
- Stoica S
- Stone J
- Strait J
- Strait M
- Strauss T
- Striganov S
- Sulej R
- Sullivan G
- Sun Y
- Suter L
- Sutera CM
- Svoboda R
- Szczerbinska B
- Szelc AM
- Söldner-Rembold S
- Talaga R
- Tariq S
- Tatar E
- Tayloe R
- Terao K
- Thiesse M
- Thompson LF
- Thomson M
- Thorn C
- Tian X
- Tiedt D
- Timm SC
- Todd J
- Tonazzo A
- Tope T
- Torres FR
- Torti M
- Tortola M
- Tortorici F
- Toups M
- Touramanis C
- Trevor J
- Tripathi M
- Tropin I
- Trzaska WH
- Tsai Y
- Tsang KV
- Tsaris A
- Tsenov R
- Tufanli S
- Tull C
- Turner J
- Tzanov M
- Tziaferi E
- Uchida Y
- Urheim J
- Usher T
- Vagins MR
- Vahle P
- Valdiviesso GA
- Valerio L
- Vallari Z
- Valle J
- Varanini F
- Varner G
- Vasseur G
- Vaziri K
- Velev G
- Ventura S
- Verdugo A
- Vermeulen MA
- Vernon E
- Viant T
- Vieira TV
- Vignoli C
- Vihonen S
- Vilela C
- Villanueva AC
- Viren B
- Vokac P
- Vrba T
- Vries JJD
- Wachala T
- Wahl D
- Wallbank M
- Wang B
- Wang H
- Wang T
- Warburton TK
- Warner D
- Wascko M
- Water RVD
- Waters D
- Weber A
- Weber M
- Wei W
- Weinstein A
- Wengin X
- Wenman D
- Wetstein M
- White A
- Whitehead LH
- Whittington D
- Wilking MJ
- Willhite J
- Wilson P
- Wilson RJ
- Wittich P
- Wolcott J
- Wong HH
- Wongjirad T
- Wood K
- Wood LS
- Worcester E
- Worcester M
- Wu S
- Yanagisawa C
- Yang S
- Yang T
- Ye J
- Yeh M
- Yershov N
- Yonehara K
- Yu B
- Yu J
- Zalesak J
- Zambelli L
- Zamorano B
- Zang L
- Zani A
- Zaremba K
- Zeller GP
- Zhang C
- Zhang C
- Zhou Y
- Zimmerman ED
- Zito M
- Zuklin J
- Zutshi V
- Zwaska R
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ProtoDUNE-SP is the single-phase DUNE Far Detector prototype that is under construction and will be operated at the CERN Neutrino Platform (NP) starting in 2018. ProtoDUNE-SP, a crucial part of the DUNE effort towards the construction of the first DUNE 10-kt fiducial mass far detector module (17 kt total LAr mass), is a significant experiment in its own right. With a total liquid argon (LAr) mass of 0.77 kt, it represents the largest monolithic single-phase LArTPC detector to be built to date. It's technical design is given in this report
Personal non-commercial use only. The Journal of Rheumatology ClinicalTrials.gov identifier NCT00139776
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- 30/04/2020
- Field of study
ABSTRACT. Objective. To determine whether "continuous" celecoxib is more efficacious than "intermittent" use in preventing osteoarthritis (OA) flares of the knee and/or hip. Methods. A double-blind, randomized, multicenter international study comparing efficacy and safety of continuous (daily) versus intermittent (as required during predefined OA flare) celecoxib 200 mg/day in 858 subjects, aged 18-80 years. The study consisted of 3 periods: (I) screening/washout visit; (II) open-label run-in with celecoxib; and (III) 22-week blinded treatment. Only subjects whose OA flares resolved in Period 2 (without subsequent flare) were randomized. The primary endpoint, number of flares per time of exposure during Period III (number of flares per month), was compared using analysis of variance with treatment as the independent variable. Acetaminophen was available as rescue medication. Results. Of 875 subjects randomized to treatment, 858 subjects received treatment. At randomization > 70% were female; mean age 58.6 years; mean disease duration 6.5 years; total Western Ontario and McMaster Universities Osteoarthritis Index mean score 25.8; ~45% had hypertension; and ~20% were using aspirin (for cardiovascular prophylaxis). Subjects receiving continuous treatment reported 42% fewer OA flares/month than intermittent users (p < 0.0001) or 2.0 fewer OA flares over 22 weeks. Statistical and clinically meaningful benefits in secondary outcomes were also evident with continuous treatment. There were no differences in adverse events (AE) or newonset/aggravated hypertension. Conclusion. Continuous treatment with celecoxib 200 mg/day was significantly more efficacious than intermittent use in preventing OA flares of the hip and knee, without an increase in overall AE, including gastrointestinal disorders and hypertension, during 22 weeks of treatment
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