Grid Computing: A Desirable Tool for Electronic Governance

This paper explained how Government at different levels can apply Information and Communication Technology (ICT) to achieve efficiency, effectiveness, transparency and accountability in Government to Government (G2G), Government to Employee (G2E), Government to Citizen (G2C) and Government to Business (G2B).   This application is referred to as Electronic Governance (e-Governance).  The system enables citizens to make best use of automated administration processes that are accessible on-line.  Grid computing is an ideal solution to this type of administrative processes.  This paper therefore presents how Grid computing can be used to effectively and efficiently meet the yearnings of citizenry.   Generally, we demonstrated the creation of a virtual environment by using Grid technologies to a specific e-governance application on distributed resources. We presented a framework for the adoption of grid computing for                   e-governance management using Electronic Bill server (EB server), Comprehensive Welfare and Social Services server (CWSS server) and Corporation sever (C server).  Experiments were run with the Grid environment and without Grid environment by considering the number of jobs completed and the period to complete various jobs submitted for processing using MATLAB. The numbers of jobs completed by EB server by using Grid are: 20, 40, 60, 80,100 and 120 while 15, 25, 33, 60, 72 and 90 were completed without Grid under the same condition.  The numbers of jobs completed by CWSS server with Grid are: 30,50,70,90,120 and 130 while 22.5, 37.5, 52.5, 67.5 90 and 97.5 were completed without Grid.   The numbers of jobs completed by Corporation server under Grid are: 30,50,70,90,120 and 130 while 24, 40,56,72,96 and 104 were completed without Grid.   The period to complete various jobs submitted for processing by the EB server under Grid are: 18, 30, 42, 54,72 and 88minutes while 30,50,70,90,120 and 130minutes were required without Grid.  For CWSS server, the period to complete various jobs submitted for processing under Grid are: 6.5, 19.5, 32.5, 45.5, 58.5,78 and 84.5minutes while 10, 30,50,70,90,120 and 130minutes were required without Grid.  For Corporation server, the period to complete various jobs submitted for processing under Grid are:  6.4,19.2,32,44.8,57.6, 76.8 and 82.2minutes while 10,30,50,70,90 120, and 130minutes were required without Grid. The result of simulation revealed that implementing an e-Governance solution was cost effective, efficient, consistent and reduced job processing time with high quality of result and providing better services to citizens. Keywords: E-Governance, Grid Applications, Grid Computing, Grid environment, Grid Infrastructure and Grid Resource Broker

Teacher Quality Factors as Determinant of Students’ Achievement in Mathematics

This paper tries to find out the effect of teacher quality factors on students achievement in Mathematics. The teacher qualities that were considered in the study include teachers’ experience, qualification motivation interest satisfaction and teaching techniques. The data for the study were collected through the questionnaires designed for the teachers and students result collected. Analysis of variance (ANOVA) and regression analysis were used to analyze the data. It was found out that all the teacher qualities considered in the study determine the achievement of student in Mathematics to a large extent. Keywords: Teacher Quality, Achievement, Motivation, Teachers’ Qualification, Experienc

Computational Numerical Solution for Traveling Salesman Problem

This paper examined and analyzed the desire of Traveling Salesman Problem (TSP) to find the cheapest way of visiting all given set of cities and returning to the starting point.     We presented a unique decomposition approach model for TSP in which the requirements and features of practical application in communication network, road transportation and supply chains are put into consideration.  We used a Mathematical Modeling solution with the application of Ant Colony Search Algorithm (ACSA) approach for result computation.  In our approach, different Agents were created for difference purposes.   Information agent gathered information about best tour and detected the solution agent that arrived at a given point with information message containing details of where the solution agent has come from as well as best tour cost.  The place ant performs local pheromone decay on the relevant links.   This help to avoid random visit to irrelevant edges and allows the place ant to calculate the cost of tour of all place ants including the latest pheromone level on the links to each of the place ants. The solution agent uses available information to decide  which node to visit next and informs the place ant of  its decision to move to a given destination and update better tour  previously sampled while information about where to go next also obtained.  The place ant updates its pheromone value for that link using the equivalent of the algorithm for local pheromone update.  The cycle continues until solution agent arrives at its destination. The main advantage of our approach is that it permits the use of mixed integer programming and combinatorial optimization techniques to compute real optimal routing path, solving the problem in practice by returning actual shortest route with its numerical value and not the best effort result as provided by some previous models and analytical methods. The implementation was carried out using C# programming language.  Data used were generated and the performance evaluation of the model was carried out through simulation using Matlab 7.0.  The result shows that by considering all possible paths between a node as the source and another as the destination, all possible routes for a particular journey with shortest route in each case were generated. Keywords: Ant Colony, Combinatorial Optimization, Mixed Integer Programming, Pheromone, Search Algorithm and Traveling Salesman

Seatbelt use and risk of major injuries sustained by vehicle occupants during motor-vehicle crashes: A systematic review and meta-analysis of cohort studies

BackgroundIn 2004, a World Health Report on road safety called for enforcement of measures such as seatbelt use, effective at minimizing morbidity and mortality caused by road traffic accidents. However, injuries caused by seatbelt use have also been described. Over a decade after publication of the World Health Report on road safety, this study sought to investigate the relationship between seatbelt use and major injuries in belted compared to unbelted passengers.MethodsCohort studies published in English language from 2005 to 2018 were retrieved from seven databases. Critical appraisal of studies was carried out using the Scottish Intercollegiate Guidelines Network (SIGN) checklist. Pooled risk of major injuries was assessed using the random effects meta-analytic model. Heterogeneity was quantified using I-squared and Tau-squared statistics. Funnel plots and Egger's test were used to investigate publication bias. This review is registered in PROSPERO (CRD42015020309).ResultsEleven studies, all carried out in developed countries were included. Overall, the risk of any major injury was significantly lower in belted passengers compared to unbelted passengers (RR 0.47; 95%CI, 0.29 to 0.80; I-2=99.7; P=0.000). When analysed by crash types, belt use significantly reduced the risk of any injury (RR 0.35; 95%CI, 0.24 to 0.52). Seatbelt use reduces the risk of facial injuries (RR=0.56, 95% CI=0.37 to 0.84), abdominal injuries (RR=0.87; 95% CI=0.78 to 0.98) and, spinal injuries (RR=0.56, 95% CI=0.37 to 0.84). However, we found no statistically significant difference in risk of head injuries (RR=0.49; 95% CI=0.22 to 1.08), neck injuries (RR=0.69: 95%CI 0.07 to 6.44), thoracic injuries (RR 0.96, 95%CI, 0.74 to 1.24), upper limb injuries (RR=1.05, 95%CI 0.83 to 1.34) and lower limb injuries (RR=0.77, 95%CI 0.58 to 1.04) between belted and non-belted passengers.ConclusionIn sum, the risk of most major road traffic injuries is lower in seatbelt users. Findings were inconclusive regarding seatbelt use and susceptibility to thoracic, head and neck injuries during road traffic accidents. Awareness should be raised about the dangers of inadequate seatbelt use. Future research should aim to assess the effects of seatbelt use on major injuries by crash type

Inhaled carbon monoxide protects against the development of shock and mitochondrial injury following hemorrhage and resuscitation

Aims: Currently, there is no effective resuscitative adjunct to fluid and blood products to limit tissue injury for traumatic hemorrhagic shock. The objective of this study was to investigate the role of inhaled carbon monoxide (CO) to limit inflammation and tissue injury, and specifically mitochondrial damage, in experimental models of hemorrhage and resuscitation. Results: Inhaled CO (250 ppm for 30 minutes) protected against mortality in severe murine hemorrhagic shock and resuscitation (HS/R) (20% vs. 80%; P<0.01). Additionally, CO limited the development of shock as determined by arterial blood pH (7.25±0.06 vs. 7.05±0.05; P<0.05), lactate levels (7.2±5.1 vs 13.3±6.0; P<0.05), and base deficit (13±3.0 vs 24±3.1; P<0.05). A dose response of CO (25-500 ppm) demonstrated protection against HS/R lung and liver injury as determined by MPO activity and serum ALT, respectively. CO limited HS/R-induced increases in serum tumor necrosis factor-α and interleukin-6 levels as determined by ELISA (P<0.05 for doses of 100-500ppm). Furthermore, inhaled CO limited HS/R induced oxidative stress as determined by hepatic oxidized glutathione:reduced glutathione levels and lipid peroxidation. In porcine HS/R, CO did not influence hemodynamics. However, CO limited HS/R-induced skeletal muscle and platelet mitochondrial injury as determined by respiratory control ratio (muscle) and ATP-linked respiration and mitochondrial reserve capacity (platelets). Conclusion: These preclinical studies suggest that inhaled CO can be a protective therapy in HS/R; however, further clinical studies are warranted

‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services

Background: Once considered to be a disorder restricted to childhood, Attention Deficit/Hyperactivity Disorder (ADHD) is now recognised to persist into adult life. However, service provision for adults with ADHD is limited. Additionally, there is little guidance or research on how best to transition young people with ADHD from child to adult services. Method: We report the findings of a survey of 96 healthcare professionals working in children’s (Child and Adolescent Mental Health Services and Community Paediatrics) and adult services across five NHS Trusts within the East Midlands region of England to gain a better understanding of the current provision of services for young people with ADHD transitioning into adult mental health services. Results: Our findings indicate a lack of structured guidelines on transitioning and little communication between child and adult services. Child and adult services had differing opinions on what they felt adult services should provide for ADHD cases. Adult services reported feeling ill-prepared to deal with ADHD patients, with clinicians in these services citing a lack of specific knowledge of ADHD and a paucity of resources to deal with such cases. Conclusions: We discuss suggestions for further research, including the need to map the national provision of services for adults with ADHD, and provide recommendations for commissioned adult ADHD services. We specifically advocate an increase in ADHD-specific training for clinicians in adult services, the development of specialist adult ADHD clinics and greater involvement of Primary Care to support the work of generic adult mental health services in adult ADHD management

The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review

Attention deficit hyperactivity disorder (ADHD) is typically diagnosed using clinical observation and subjective informant reports. Once children commence ADHD medication, robust monitoring is required to detect partial or non-responses. The extent to which neuropsychological continuous performance tests (CPTs) and objective measures of activity can clinically aid the assessment and titration process in ADHD is not fully understood. This review describes the current evidence base for the use of CPTs and objectively measured activity to support the diagnostic procedure and medication management for children with ADHD. Four databases (PsycINFO, Medline, Allied and Complementary Medicine (AMED) and PsycARTICLES) were systematically searched to understand the current evidence base for: (1) the use of CPTs to aid clinical assessment of ADHD; (2) the use of CPTs to aid medication management; (3) the clinical utility of objective measures of activity in ADHD. Sixty relevant articles were identified. The search revealed six commercially available CPTs that had been reported on for their clinical use. There were mixed findings with regard to the use of CPTs to assess and manage medication, with contrasting evidence on their ability to support clinical decision making. There was a strong evidence base for the use of objective measures of activity to aid ADHD/non-ADHD group differentiation, which appears sensitive to medication effects and would also benefit from further research on their clinical utility. The findings suggest that combining CPTs and an objective measure of activity may be particularly useful as a clinical tool and worthy of further pursuit

A collaboratively derived international research agenda on legislative science advice

© 2019, The Author(s). The quantity and complexity of scientific and technological information provided to policymakers have been on the rise for decades. Yet little is known about how to provide science advice to legislatures, even though scientific information is widely acknowledged as valuable for decision-making in many policy domains. We asked academics, science advisers, and policymakers from both developed and developing nations to identify, review and refine, and then rank the most pressing research questions on legislative science advice (LSA). Experts generally agree that the state of evidence is poor, especially regarding developing and lower-middle income countries. Many fundamental questions about science advice processes remain unanswered and are of great interest: whether legislative use of scientific evidence improves the implementation and outcome of social programs and policies; under what conditions legislators and staff seek out scientific information or use what is presented to them; and how different communication channels affect informational trust and use. Environment and health are the highest priority policy domains for the field. The context-specific nature of many of the submitted questions—whether to policy issues, institutions, or locations—suggests one of the significant challenges is aggregating generalizable evidence on LSA practices. Understanding these research needs represents a first step in advancing a global agenda for LSA research

Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)

Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic