158 research outputs found
Exposure Test on Two Surface Anticorrosion Technologies for Marine Concrete Structure
This paper is to study the effect of surface coating and silane hydrophobic agents for high performance concrete durability in a marine environment of tidal zone and splash zone by exposure test in JiaoZhou Bay. The results indicated that surface coating had good protection and coating quality after a 5-year period and the adhesive strength with concrete surface was more than 2.5 MPa. Surface coating can effectively improve chloride ion penetration resistance of concrete structures. The substrate concrete of specimen treated with silane had some chloride ion penetration, but compared with untreated concrete, chloride content of silane-treated concrete within 10 mm depth from surface was reduced by 43 and 67% in the tidal zone and the splash zone, respectively. Two surface anticorrosion measures technologies were effective in reducing the chloride erosion and improved the service life of marine concrete structure
Mixed‐cation LiCa‐LSX zeolite with minimum lithium for air separation
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141696/1/aic16032.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141696/2/aic16032_am.pd
Bridging the Gap:Cross-modal Knowledge Driven Network for Radiology Report Generation
Radiology report generation aims to generate medical reports based on given medical images, which can alleviate the workload of radiologists and has attracted significant research interest in recent years. However, existing studies have struggled to bridge the gap between the two different modalities (i.e. image and text) and generate clinically accurate reports. This is primarily due to the challenges in modelling the crossmodal mappings and the inefficiency of transferring knowledge across modalities. To address these challenges, in this paper, we propose to leverage a pre-constructed knowledge graph as a shared matrix that bridges the gap between visual and textual information, facilitating cross-modal knowledge transfer. This shared knowledge matrix effectively captures cross-modal mappings and aligns information between images and texts, thereby bridging the gap between modalities. Specifically, we propose a new module for knowledge distillation and preservation that integrates relevant knowledge representations into both visual and textual inputs, facilitating intuitive cross-modal knowledge interaction and enhancing the clinical accuracy of the generated reports. Experimental results on two benchmark datasets show the effectiveness of our method, outperforming state-of-the-arts in report generation
CL-MVSNet:Unsupervised Multi-view Stereo with Dual-level Contrastive Learning
Unsupervised Multi-View Stereo (MVS) methods have achieved promising progress recently. However, previous methods primarily depend on the photometric consistency assumption, which may suffer from two limitations: indistinguishable regions and view-dependent effects, e.g., low-textured areas and reflections. To address these issues, in this paper, we propose a new dual-level contrastive learning approach, named CL-MVSNet. Specifically, our model integrates two contrastive branches into an unsupervised MVS framework to construct additional supervisory signals. On the one hand, we present an image-level contrastive branch to guide the model to acquire more context awareness, thus leading to more complete depth estimation in indistinguishable regions. On the other hand, we exploit a scene-level contrastive branch to boost the representation ability, improving robustness to view-dependent effects. Moreover, to recover more accurate 3D geometry, we introduce an ℒ0.5 photometric consistency loss, which encourages the model to focus more on accurate points while mitigating the gradient penalty of undesirable ones. Extensive experiments on DTU and Tanks&Temples benchmarks demonstrate that our approach achieves state-of-the-art performance among all end-to-end unsupervised MVS frameworks and outperforms its supervised counterpart by a considerable margin without fine-tuning
Enzyme-mediated nitric oxide production in vasoactive erythrocyte membrane-enclosed coacervate protocells
Regulation of AChR Clustering by Dishevelled Interacting with MuSK and PAK1
AbstractAn important aspect of synapse development is the clustering of neurotransmitter receptors in the postsynaptic membrane. Although MuSK is required for acetylcholine receptor (AChR) clustering at the neuromuscular junction (NMJ), the underlying molecular mechanisms remain unclear. We report here that in muscle cells, MuSK interacts with Dishevelled (Dvl), a signaling molecule important for planar cell polarity. Disruption of the MuSK-Dvl interaction inhibits Agrin- and neuron-induced AChR clustering. Expression of dominant-negative Dvl1 in postsynaptic muscle cells reduces the amplitude of spontaneous synaptic currents at the NMJ. Moreover, Dvl1 interacts with downstream kinase PAK1. Agrin activates PAK, and this activation requires Dvl. Inhibition of PAK1 activity attenuates AChR clustering. These results demonstrate important roles of Dvl and PAK in Agrin/MuSK-induced AChR clustering and reveal a novel function of Dvl in synapse development
General synthesis of 2D rare-earth oxide single crystals with tailorable facets
Two-dimensional (2D) rare-earth oxides (REOs) are a large family of materials with various intriguing applications and precise facet control is essential for investigating new properties in the 2D limit. However, a bottleneck remains with regard to obtaining their 2D single crystals with specific facets because of the intrinsic non-layered structure and disparate thermodynamic stability of different facets. Herein, for the first time, we achieve the synthesis of a wide variety of high-quality 2D REO single crystals with tailorable facets via designing a hard-soft-acid-base couple for controlling the 2D nucleation of the predetermined facets and adjusting the growth mode and direction of crystals. Also, the facet-related magnetic properties of 2D REO single crystals were revealed. Our approach provides a foundation for further exploring other facet-dependent properties and various applications of 2D REO, as well as inspiration for the precise growth of other non-layered 2D materials
Malignant B Cells Induce the Conversion of CD4+CD25− T Cells to Regulatory T Cells in B-Cell Non-Hodgkin Lymphoma
Recent evidence has demonstrated that regulatory T cells (Treg) were enriched in the tumor sites of patients with B-cell non-Hodgkin lymphoma (NHL). However, the causes of enrichment and suppressive mechanisms need to be further elucidated. Here we demonstrated that CD4+CD25+FoxP3+CD127lo Treg were markedly increased and their phenotypes were different in peripheral blood (PB) as well as bone marrow (BM) from newly diagnosed patients with B-cell NHL compared with those from healthy volunteers (HVs). Involved lymphatic tissues also showed higher frequencies of Treg than benign lymph nodes. Moreover, the frequencies of Treg were significantly higher in involved lymphatic tissues than those from PB as well as BM in the same patients. Suppression mediated by CD4+CD25+ Treg co-cultured with allogeneic CFSE-labeled CD4+CD25− responder cells was also higher in involved lymphatic tissues from B-cell NHL than that mediated by Treg from HVs. In addition, we found that malignant B cells significantly induced FoxP3 expression and regulatory function in CD4+CD25− T cells in vitro. In contrast, normal B cells could not induce the conversion of CD4+CD25− T cells to Treg. We also showed that the PD-1/B7-H1 pathway might play an important role in Treg induction. Taken together, our results suggest that malignant B cells induce the conversion of CD4+CD25− T cells to Treg, which may play a role in the pathogenesis of B-cell NHL and represent a promising therapeutic target
Application of the Resistivity in Quality Control of Concrete Durability for the Hong Kong–Zhuhai–Macao Bridge
Engineering uses the chloride ion diffusion coefficient as the durability of concrete quality control indicators under the marine environment, due to the chloride ion diffusion coefficient and the electrical resistivity of concrete parameters are reflected in the concrete pore structure, and resistivity testing is convenient, fast advantages, the resistivity alternative chloride ion diffusion coefficient for the durability of concrete quality control has practical significance. In this paper, using concrete mix of the immersed tube tunnel in Hong Kong–Zhuhai–Macao Bridge as research object, Under the standard curing conditions (temperature 20±2°C, 95% RH or more), Through the different ages of the specimen tested, Wenner method resistivity test results are more stable than the RCM chloride diffusion coefficient of the test results. Building the relationships between resistivity and chloride diffusion coefficient, and resistivity tests the specimen which is the entire structure of retention, compared with the result of the actual measured RCM method of chloride diffusion coefficient, average value of the diffusion coefficient what is concluded by resistivity is higher than real one, using the resistivity for the durability of control indicators is conservative, more demanding of the quality of concrete materials. Therefore, using resistivity as index to monitor changes of the materials is possible
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