90 research outputs found
COMPLEX ESTIMATION OF BRONCHOPULMONARY SYSTEM IN PATIENTS WITH HODGKINS LYMPHOMA
One of the important problems with patients with Hodgkin's lymphoma is lung injury, caused both by a tumor effect and the influence of chemoradiotherapy. Before the treatment an obstructive lung function pattern connected with tumor substrate has been revealed in 38% of cases. After chemoradiotherapy the restrictive lung pattern was shown in 14% of the patients and mixed lung pattern was seen in 12% of the cases, which were caused by the development of pneumosclerosis and emphysema
Gradients of Taxonomic Diversity among Local Floras in the Russian Arctic
Latitudinal and longitudinal changes in taxonomic variables were analyzed in 319 local floras in the Russian Arctic. Within the studied segment of latitudinal gradient, most changes can be described in terms of linear regression with negative coefficients (a number of species, genera and families), or positive coefficients (a proportion of the leading families and genera). However, the mean number of species in a family or genus almost does not change with increasing latitude, although it slightly increases as one moves eastward. The proportion of monocots does not correlate with latitude, but slightly decreases as one moves eastward. Proportions of various families change asynchronously. Although correlation with longitude was less pronounced, mean species richness was specific to many subprovinces, even within a certain subzone. These differences reflect both the diversity of landscapes and the history of flora formation.
Keywords: the Arctic, local floras, latitudinal and longitudinal gradient, floristic subprovince
ΠΠΠ’ΠΠΠΠΠΠ¦ΠΠ― ΠΠΠΠΠΠΠ‘Π’ΠΠΠ Π¦ΠΠ’ΠΠΠΠΠΠΠΠΠΠ Π£Π‘ΠΠΠ ΠΠΠ€ΠΠΠ¦ΠΠ Π£ ΠΠΠ’ΠΠ ΠΠΠΠΠ¨ΠΠΠ ΠΠΠΠ ΠΠ‘Π’Π
The results of a laboratory examination of 520 children aged 1β3 years are presented. The examination was conducted to determine the DNA of cytomegalovirus in children with acute cytomegalovirus infection in various biological media by polymerase chain reaction. The differences in the virus sheddingΒ into the blood, saliva, and urine are established: the median of the viral load for saliva is 4.9 lg copies of DNA/ml, the blood 3.4 lg copies of DNA/ml, urine β 3.85 lg copies of DNA/ml. The cut of extreme values of the viral load are determined with the help of mathematical modeling which determine the clinical probability of developing acute CMV infection which allows for more accurate and timely assignment of etiotropic therapy.ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ 520 Π΄Π΅ΡΠ΅ΠΉ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 1β3 Π»Π΅Ρ. ΠΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΎΡΡ Ρ ΡΠ΅Π»ΡΡ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡΒ ΠΠΠ ΡΠΈΡΠΎΠΌΠ΅Π³Π°Π»ΠΎΠ²ΠΈΡΡΡΠ° Π² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ΅Π΄Π°Ρ
, ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΠΏΠΎΠ»ΠΈΠΌΠ΅ΡΠ°Π·Π½ΠΎΠΉ ΡΠ΅ΠΏΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ Ρ Π΄Π΅ΡΠ΅ΠΉ, Ρ ΠΎΡΡΡΠΎΠΉ ΡΠΈΡΠΎΠΌΠ΅Π³Π°Π»ΠΎΠ²ΠΈΡΡΡΠ½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π² ΡΠΎΡΠΌΠ΅ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ½ΠΎΠ½ΡΠΊΠ»Π΅ΠΎΠ·Π°.Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Ρ ΡΠ°Π·Π»ΠΈΡΠΈΡ Π²ΠΈΡΡΡΠΎΠ²ΡΠ΄Π΅Π»Π΅Π½ΠΈΡ Π² ΠΊΡΠΎΠ²Ρ, ΡΠ»ΡΠ½Ρ, ΠΈ ΠΌΠΎΡΡ: ΠΌΠ΅Π΄ΠΈΠ°Π½Π° Π²ΠΈΡΡΡΠ½ΠΎΠΉ Π½Π°Π³ΡΡΠ·ΠΊΠΈ Π΄Π»Ρ ΡΠ»ΡΠ½Ρ ΡΠΎΡΡΠ°Π²Π»ΡΠ΅Ρ 4,9 lg ΠΊΠΎΠΏΠΈΠΉ ΠΠΠ/ΠΌΠ», ΠΊΡΠΎΠ²ΠΈ β 3,4 lg ΠΊΠΎΠΏΠΈΠΉ ΠΠΠ/ΠΌΠ», ΠΌΠΎΡΠΈΒ β 3,85 lg ΠΊΠΎΠΏΠΈΠΉ ΠΠΠ/ΠΌΠ». Π‘ ΠΏΠΎΠΌΠΎΡΡΡ ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Ρ Β«ΠΏΠΎΡΠΎΠ³ΠΎΠ²ΡΠ΅Β» Π·Π½Π°ΡΠ΅Π½ΠΈΡ Π²ΠΈΡΡΡΠ½ΠΎΠΉ Π½Π°Π³ΡΡΠ·ΠΊΠΈ, ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡΠΈΠ΅Β ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΡΡ Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΡ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΎΡΡΡΠΎΠΉ Π¦ΠΠΠ, ΡΡΠΎ Π΄Π°Π΅Ρ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ Π±ΠΎΠ»Π΅Π΅ ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΈ ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ Π½Π°Π·Π½Π°ΡΠ΅Π½ΠΈΡ ΡΡΠΈΠΎΡΡΠΎΠΏΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ
Π‘ΠΠ£Π§ΠΠ ΠΠΠ€Π€Π£ΠΠΠΠ Π-ΠΠ Π£ΠΠΠΠΠΠΠ’ΠΠ§ΠΠΠ ΠΠΠΠ€ΠΠΠ« Π‘ Π€Π£ΠΠΠ¦ΠΠΠΠΠΠ¬ΠΠ ΠΠΠΠ§ΠΠΠ«ΠΠ ΠΠΠ’Π ΠΠΠΠ«ΠΠ ΠΠ£Π’ΠΠ¦ΠΠ―ΠΠ Π ΠΠΠΠ Π’Π 53
Background. the presence of functionally significant intron mutations in the TP53 gene was demonstratedΒ in experiments in vitro and on samples of patients with some variants of non-Hodgkinβs lymphomas. to date,Β the studies of TP53 in tumor tissue of patients with diffuse large B-cell lymphoma (dlBCl) have been focusedΒ on the mutations in 5β8 exons of the gene. For these reasons, further studies of the spectrum of changes inΒ the intron sequences of the TP53 gene and the determination of their functional effect in dlBCl are required.Description. We present two case reports that are of interest as the cases for detection of functionallyΒ significant intron TP53 mutations in dlBCl tissue, first published in the Russian scientific literature. the firstΒ clinical case of dlBCl was clinically characterized by extranodal tumor at the onset of the disease, severeΒ symptoms of tumor intoxication, high paraclinical tumor activity, and early hemoblastosis recurrence. theΒ second case of dlBCl was characterized by initially massive tumor lesion, rapidly progressive course of theΒ disease, severe symptoms of tumor intoxication, high paraclinical tumor activity and poor response to therapyΒ with subsequent generalization of lymphoma. Conclusion. Mutations in the TP53 gene are the driver of theΒ tumor process, serve not only as a marker of aggressive tumor progression, but also as an independentΒ predictor of reduced sensitivity to treatment. the presented clinical cases show that an in-depth analysis ofΒ the results of the TP53 sequencing in tumors and functional assessment of all detected changes, includingΒ changes in the introns of the gene and involving in silico analysis techniques, are necessary.Β Β ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ. Π½Π°Π»ΠΈΡΠΈΠ΅ Π² Π³Π΅Π½Π΅ Π’Π 53 ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎ Π·Π½Π°ΡΠΈΠΌΡΡ
ΠΈΠ½ΡΡΠΎΠ½Π½ΡΡ
ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π±ΡΠ»ΠΎ ΠΏΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π½ΠΎ Π² ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Ρ
in vitro ΠΈ Π½Π° Π²ΡΠ±ΠΎΡΠΊΠ°Ρ
Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΎΡΠ΄Π΅Π»ΡΠ½ΡΠΌΠΈ Π²Π°ΡΠΈΠ°Π½ΡΠ°ΠΌΠΈ Π½Π΅Ρ
ΠΎΠ΄ΠΆΠΊΠΈΠ½ΡΠΊΠΈΡ
Π»ΠΈΠΌΡΠΎΠΌ. ΠΠΎ Π½Π°ΡΡΠΎΡΡΠ΅Π³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ ΠΏΡΠΈ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠΈ Π’Π 53 Π² ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ
Π΄ΠΈΡΡΡΠ·Π½ΠΎΠΉΒ Π-ΠΊΡΡΠΏΠ½ΠΎΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠΉ Π»ΠΈΠΌΡΠΎΠΌΠΎΠΉ (ΠΠΠΊΠΊΠ») ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»ΠΈ ΡΠΎΡΡΠ΅Π΄ΠΎΡΠΎΡΠ΅Π½Ρ Π½Π° ΠΏΠΎΠΈΡΠΊΠ΅ ΠΌΡΡΠ°ΡΠΈΠΉ Π² 5β8Β ΡΠΊΠ·ΠΎΠ½Π°Ρ
Π³Π΅Π½Π°. ΠΠΎ ΡΡΠΈΠΌ ΠΏΡΠΈΡΠΈΠ½Π°ΠΌ ΡΡΠ΅Π±ΡΡΡΡΡ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠΈΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠΏΠ΅ΠΊΡΡΠ° ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π² ΠΈΠ½ΡΡΠΎΠ½Π½ΡΡ
Β ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡΡ
Π³Π΅Π½Π° Π’Π 53 ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΈΡ
ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΠ΅ΠΊΡΠ° ΠΏΡΠΈ ΠΠΠΊΠΊΠ». ΠΠΏΠΈΡΠ°Π½ΠΈΠ΅.Β Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ Π΄Π²Π° ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΡ, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡ ΠΈΠ½ΡΠ΅ΡΠ΅Ρ ΠΊΠ°ΠΊ Π²ΠΏΠ΅ΡΠ²ΡΠ΅Β ΠΏΡΠ±Π»ΠΈΠΊΡΠ΅ΠΌΡΠ΅ Π² ΡΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ Π½Π°ΡΡΠ½ΠΎΠΉ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ΅ ΡΠ»ΡΡΠ°ΠΈ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎ Π·Π½Π°ΡΠΈΠΌΡΡ
ΠΈΠ½ΡΡΠΎΠ½Π½ΡΡ
Β ΠΌΡΡΠ°ΡΠΈΠΉ Π’Π 53 Π² ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ ΠΠΠΊΠΊΠ». ΠΠ΅ΡΠ²ΡΠΉ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠ»ΡΡΠ°ΠΉ ΠΠΠΊΠΊΠ» Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΠΎΠ²Π°Π»ΡΡΒ ΡΠΊΡΡΡΠ°Π½ΠΎΠ΄Π°Π»ΡΠ½ΡΠΌ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΡΠΌ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΠ΅ΠΌ Π² Π΄Π΅Π±ΡΡΠ΅ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ, Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΡΠΌΠΈ ΡΠΈΠΌΠΏΡΠΎΠΌΠ°ΠΌΠΈ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠΉΒ ΠΈΠ½ΡΠΎΠΊΡΠΈΠΊΠ°ΡΠΈΠΈ, Π²ΡΡΠΎΠΊΠΎΠΉ ΠΏΠ°ΡΠ°ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ, ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΡΠ°Π½Π½Π΅Π³ΠΎ ΡΠ΅ΡΠΈΠ΄ΠΈΠ²Π° Π³Π΅ΠΌΠΎΠ±Π»Π°ΡΡΠΎΠ·Π° Ρ ΡΠΊΡΡΡΠ°Π½ΠΎΠ΄Π°Π»ΡΠ½ΡΠΌ ΠΎΡΠ°Π³ΠΎΠΌ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ Π² Π·Π°Π±Π°ΡΡΠ΅ΡΠ½ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ, ΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΡΠΌ ΠΊ Π»Π΅ΡΠ΅Π½ΠΈΡ. ΠΡΠΎΡΠΎΠΉΒ ΠΎΠΏΠΈΡΠ°Π½Π½ΡΠΉ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠ»ΡΡΠ°ΠΉ ΠΠΠΊΠΊΠ» Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΠΎΠ²Π°Π»ΡΡ ΠΈΡΡ
ΠΎΠ΄Π½ΠΎ ΠΌΠ°ΡΡΠΈΠ²Π½ΡΠΌ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΡΠΌ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΠ΅ΠΌ,Β Π±ΡΡΡΡΠΎΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΡΡΡΠΈΠΌ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ΠΌ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ, Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΡΠΌΠΈ ΡΠΈΠΌΠΏΡΠΎΠΌΠ°ΠΌΠΈ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠΉ ΠΈΠ½ΡΠΎΠΊΡΠΈΠΊΠ°ΡΠΈΠΈ,Β Π²ΡΡΠΎΠΊΠΎΠΉ ΠΏΠ°ΡΠ°ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΈ ΠΏΠ»ΠΎΡ
ΠΈΠΌ ΠΎΡΠ²Π΅ΡΠΎΠΌ Π½Π° ΡΠ΅ΡΠ°ΠΏΠΈΡ Ρ ΠΏΠΎΡΠ»Π΅Π΄ΡΡΡΠ΅ΠΉ Π³Π΅Π½Π΅ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠ΅ΠΉ Π»ΠΈΠΌΡΠΎΠΌΡ. ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΡΡΠ°ΡΠΈΠΈ Π² Π³Π΅Π½Π΅ Π’Π 53 ΡΠ²Π»ΡΡΡΡΡ Π΄ΡΠ°ΠΉΠ²Π΅ΡΠΎΠΌ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°,Β ΡΠ»ΡΠΆΠ°Ρ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ ΠΌΠ°ΡΠΊΠ΅ΡΠΎΠΌ Π°Π³ΡΠ΅ΡΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ, Π½ΠΎ ΠΈ Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΡΠΌ ΠΏΡΠ΅Π΄ΠΈΠΊΡΠΎΡΠΎΠΌ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡΒ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΊ Π»Π΅ΡΠ΅Π½ΠΈΡ. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΠ΅ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ»ΡΡΠ°ΠΈ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ, ΡΡΠΎ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΡ ΡΠ³Π»ΡΠ±Π»Π΅Π½Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ²Β ΡΠ΅ΠΊΠ²Π΅Π½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π’Π 53 ΠΏΡΠΈ ΠΎΠΏΡΡ
ΠΎΠ»ΡΡ
ΠΈ ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½Π°Ρ ΠΎΡΠ΅Π½ΠΊΠ° Π²ΡΠ΅Ρ
Π²ΡΡΠ²Π»ΡΠ΅ΠΌΡΡ
ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ Π² ΠΈΠ½ΡΡΠΎΠ½Π°Ρ
Π³Π΅Π½Π° ΠΈ Ρ ΠΏΡΠΈΠ²Π»Π΅ΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π°Π½Π°Π»ΠΈΠ·Π° in silico.Β
ΠΠ°ΡΠ΅ΡΡΠ²ΠΎ ΠΆΠΈΠ·Π½ΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ Π½Π΅Ρ ΠΎΠ΄ΠΆΠΊΠΈΠ½ΡΠΊΠΈΠΌΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠΌΠΈ Π»ΠΈΠΌΡΠΎΠΌΠ°ΠΌΠΈ
.
ΠΠ°Π³Π½ΠΈΡΠΎΠΌΠ΅ΡΡΠΈΡ, Π°ΠΊΡΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈ ΠΈΠ½Π΅ΡΡΠΈΠ°Π»ΡΠ½ΡΠ΅ ΡΠ΅Ρ Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π² Π·Π΄ΡΠ°Π²ΠΎΠΎΡ ΡΠ°Π½Π΅Π½ΠΈΠΈ
Introduction. The problem of localization of moving objects inside buildings becomes more urgent in healthcare. Tracking the movements of patients in real time allows one to provide them with timely medical support in case of sharp deterioration in their vital signs. It is especially important to track the location of patients undergoing a surgery, since the risk of death due to postoperative complications for them is extremely high. Using indoor-positioning technologies in telemedicine systems can solve the problem, thereby reducing the mortality rate of patients and improving the quality of medical care.Aim. To study the applicability of magnetometry, inertial and acoustic technologies for patientβs localization in a hospital.Materials and methods. The analysis of domestic and foreign scientific sources devoted to indoor-positioning based on the above technologies was carried out. Material published not earlier than 2016, was chosen for the analysis. Most of the papers were published in journals with impact-factor not lower than 3.Results. After analyzing the information received, it was concluded that none of the technologies can be used independently. Inertial sensors possess high accuracy, but over time, the measurement error increases. There-fore, the sensors need to regular correction. Indoor-positioning based on geomagnetism is hampered by interference that can be induced by the operation of magnetic resonance imaging scanners and X-ray equipment, which are usually used in medical facilities. Active magnetometry does not allow to keep track of moving objects due to specific of hardware used. Ultrasound-based positioning can be complicated by ultrasonography apparatuses interference. Using an audible sound creates noise pollution and exerts a negative impact on patientβs health. Also, acoustic technologies are unable to provide a secure communication channel for data exchange.Conclusion. It is recommended to combine the reviewed positioning technologies with other technologies in order to correct the indicated disadvantages.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΌΠ΅ΡΡΠΎΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΡ
ΠΎΠ±ΡΠ΅ΠΊΡΠΎΠ² Π² Π·Π°ΠΊΡΡΡΡΡ
ΠΏΠΎΠΌΠ΅ΡΠ΅Π½ΠΈΡΡ
ΠΎΠ±ΡΠ΅ΡΠ°Π΅Ρ Π²ΡΠ΅ Π±ΠΎΠ»ΡΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ Π² ΡΡΠ΅ΡΠ΅ Π·Π΄ΡΠ°Π²ΠΎΠΎΡ
ΡΠ°Π½Π΅Π½ΠΈΡ. Π‘Π»Π΅ΠΆΠ΅Π½ΠΈΠ΅ Π·Π° ΠΏΠ΅ΡΠ΅ΠΌΠ΅ΡΠ΅Π½ΠΈΡΠΌΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π² ΡΠ΅ΠΆΠΈΠΌΠ΅ ΡΠ΅Π°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ ΠΈΠΌ ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΡΡ ΠΏΠΎΠΌΠΎΡΡ ΠΏΡΠΈ ΡΠ΅Π·ΠΊΠΎΠΌ ΡΡ
ΡΠ΄ΡΠ΅Π½ΠΈΠΈ ΠΆΠΈΠ·Π½Π΅Π½Π½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ. ΠΡΠΎΠ±Π΅Π½Π½ΠΎ Π²Π°ΠΆΠ½ΠΎ ΠΎΡΡΠ»Π΅ΠΆΠΈΠ²Π°ΡΡ ΠΌΠ΅ΡΡΠΎΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΠΏΠ΅ΡΠ΅Π½Π΅ΡΡΠΈΡ
Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π°, ΡΠ°ΠΊ ΠΊΠ°ΠΊ ΡΠΈΡΠΊ Π½Π°ΡΡΡΠΏΠ»Π΅Π½ΠΈΡ ΡΠΌΠ΅ΡΡΠΈ Π²ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΡ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ Π΄Π»Ρ Π½ΠΈΡ
ΠΊΡΠ°ΠΉΠ½Π΅ Π²ΡΡΠΎΠΊ. ΠΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΠΈΡΡΠ΅ΠΌ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΡΠ΅ΡΠΈΡΡ ΡΠΊΠ°Π·Π°Π½Π½ΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ, ΡΠ΅ΠΌ ΡΠ°ΠΌΡΠΌ ΡΠ½ΠΈΠ·ΠΈΠ² ΡΡΠΎΠ²Π΅Π½Ρ ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΈ ΠΏΠΎΠ²ΡΡΠΈΠ² ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠ³ΠΎ ΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°Π½ΠΈΡ.Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ. ΠΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΡΠΈΠΌΠ΅Π½ΠΈΠΌΠΎΡΡΠΈ ΠΌΠ°Π³Π½ΠΈΡΠΎΠΌΠ΅ΡΡΠΈΠΈ, ΠΈΠ½Π΅ΡΡΠΈΠ°Π»ΡΠ½ΡΡ
ΠΈ Π°ΠΊΡΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π΄Π»Ρ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° Π² Π·Π΄Π°Π½ΠΈΠΈ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΈ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΎΡΠ΅ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΈ Π·Π°ΡΡΠ±Π΅ΠΆΠ½ΡΡ
Π½Π°ΡΡΠ½ΡΡ
ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ², ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π½ΡΡ
Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠΌΡ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π½Π° Π±Π°Π·Π΅ ΠΏΠ΅ΡΠ΅ΡΠΈΡΠ»Π΅Π½Π½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ. ΠΠΊΠ»ΡΡΠ΅Π½Π½ΡΠ΅ Π² ΠΎΠ±Π·ΠΎΡ ΡΠ°Π±ΠΎΡΡ ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Ρ Π½Π΅ ΡΠ°Π½Π΅Π΅ 2016 Π³. ΠΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²ΠΎ ΠΈΠ· Π½ΠΈΡ
ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΎ Π² ΠΆΡΡΠ½Π°Π»Π°Ρ
Ρ impact-ΡΠ°ΠΊΡΠΎΡΠΎΠΌ Π½Π΅ Π½ΠΈΠΆΠ΅ 3.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ Π°Π½Π°Π»ΠΈΠ·Π° ΡΠ΄Π΅Π»Π°Π½ Π²ΡΠ²ΠΎΠ΄ ΠΎ ΡΠΎΠΌ, ΡΡΠΎ Π½ΠΈ ΠΎΠ΄Π½Π° ΠΈΠ· ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π½Π½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π½Π΅ ΠΌΠΎΠΆΠ΅Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡΡΡ ΡΠ°ΠΌΠΎΡΡΠΎΡΡΠ΅Π»ΡΠ½ΠΎ. ΠΠ½Π΅ΡΡΠΈΠ°Π»ΡΠ½ΡΠ΅ Π΄Π°ΡΡΠΈΠΊΠΈ ΠΎΠ±Π»Π°Π΄Π°ΡΡ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΠΎΡΠ½ΠΎΡΡΡΡ, Π½ΠΎ ΡΠΎ Π²ΡΠ΅ΠΌΠ΅Π½Π΅ΠΌ ΠΏΠΎΠ³ΡΠ΅ΡΠ½ΠΎΡΡΡ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΠΉ Π²ΠΎΠ·ΡΠ°ΡΡΠ°Π΅Ρ, ΠΏΠΎΡΡΠΎΠΌΡ ΠΎΠ½ΠΈ Π½ΡΠΆΠ΄Π°ΡΡΡΡ Π² ΠΏΠΎΡΡΠΎΡΠ½Π½ΠΎΠΉ ΠΊΠΎΡΡΠ΅ΠΊΡΠΈΡΠΎΠ²ΠΊΠ΅. ΠΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π½Π° Π±Π°Π·Π΅ Π³Π΅ΠΎΠΌΠ°Π³Π½ΠΈΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ»Ρ Π·Π°ΡΡΡΠ΄Π½ΡΠ΅ΡΡΡ ΠΏΠΎΠΌΠ΅Ρ
Π°ΠΌΠΈ, Π²ΡΠ·ΡΠ²Π°Π΅ΠΌΡΠΌΠΈ ΡΠ°Π±ΠΎΡΠΎΠΉ Π°ΠΏΠΏΠ°ΡΠ°ΡΠΎΠ² ΠΌΠ°Π³Π½ΠΈΡΠ½ΠΎ-ΡΠ΅Π·ΠΎΠ½Π°Π½ΡΠ½ΠΎΠΉ ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΠΈ ΠΈ ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠ²ΡΠΊΠΈΠΌΠΈ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠ°ΠΌΠΈ, ΠΏΠΎΠ²ΡΠ΅ΠΌΠ΅ΡΡΠ½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΡΡΠΈΠΌΠΈΡΡ Π² ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΡΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡΡ
. ΠΠΊΡΠΈΠ²Π½Π°Ρ ΠΌΠ°Π³Π½ΠΈΡΠΎΠΌΠ΅ΡΡΠΈΡ ΡΠ°ΠΊΠΆΠ΅ ΠΈΠΌΠ΅Π΅Ρ ΡΡΠ΄ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΊΠΎΠ², Π·Π°ΡΡΡΠ΄Π½ΡΡΡΠΈΡ
Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠ΅ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅. ΠΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π½Π° Π±Π°Π·Π΅ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠ° ΠΌΠΎΠΆΠ΅Ρ ΠΎΡΠ»ΠΎΠΆΠ½ΡΡΡΡΡ ΠΏΠΎΠΌΠ΅Ρ
Π°ΠΌΠΈ, Π²ΠΎΠ·Π½ΠΈΠΊΠ°ΡΡΠΈΠΌΠΈ Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΠ°Π±ΠΎΡΡ Π°ΠΏΠΏΠ°ΡΠ°ΡΠΎΠ² Π£ΠΠ. ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ»ΡΡΠΈΠΌΠΎΠ³ΠΎ Π·Π²ΡΠΊΠ° ΡΠΎΠ·Π΄Π°Π΅Ρ ΡΡΠΌΠΎΠ²ΠΎΠ΅ Π·Π°Π³ΡΡΠ·Π½Π΅Π½ΠΈΠ΅ ΠΈ Π½Π΅Π³Π°ΡΠΈΠ²Π½ΠΎ Π²Π»ΠΈΡΠ΅Ρ Π½Π° Π·Π΄ΠΎΡΠΎΠ²ΡΠ΅ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ². ΠΠΎΠΌΠΈΠΌΠΎ ΡΡΠΎΠ³ΠΎ Π°ΠΊΡΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π½Π΅ ΡΠΏΠΎΡΠΎΠ±Π½Ρ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΡΡ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΡΠΉ ΠΊΠ°Π½Π°Π» ΡΠ²ΡΠ·ΠΈ Π΄Π»Ρ ΠΎΠ±ΠΌΠ΅Π½Π° Π΄Π°Π½Π½ΡΠΌΠΈ.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π Π΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π½ΠΎ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°ΡΡ ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π½Π½ΡΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Ρ Π΄ΡΡΠ³ΠΈΠΌΠΈ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠΌΠΈ Π² ΡΠ΅Π»ΡΡ
ΡΡΡΡΠ°Π½Π΅Π½ΠΈΡ ΠΎΠ±ΠΎΠ·Π½Π°ΡΠ΅Π½Π½ΡΡ
Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΊΠΎΠ²
Π Π°Π΄ΠΈΠΎΡΠ°ΡΡΠΎΡΠ½ΡΠ΅ ΡΠ΅Ρ Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π² Π·Π΄ΡΠ°Π²ΠΎΠΎΡ ΡΠ°Π½Π΅Π½ΠΈΠΈ
Introduction. Localization of objects position in closed space plays an important role in many areas of human activity, including medicine. Using indoor-positioning technologies as a part of telemedicine systems allows one to improve the quality of medical care and to reduce mortality of patients. Therefore, indoor-positioning technologies contribute to achieve the goals outlined in the Russian Federation government`s program "Healthcare development". Aim. To study the applicability of modern radiofrequency technologies for localization of patients inside a hospital building. Materials and methods. Scientific sources devoted to indoor-positioning based on radiofrequency technologies were analyzed. The methods used included: - bibliographic retrieval; - selection and verification of sources based on their relevance; - analysis of sources by methods of deconstruction and comparative analysis . Results. The result of the analysis indicated that radiofrequency positioning technologies allow one to locate objects using radio waves properties. The disadvantage of the technology is the penetration of radio signal through walls and floors. Given this, it is necessary to use complex algorithms to detect an object with accuracy to a specific room. Despite this disadvantage, radiofrequency technologies can be used for positioning in medical facilities since they are easy in deployment and service. Also, they are used in ready-made commercial solutions. ZigBee technology is an exception because it does not allow one to track moving objects in real-time. Conclusion. Based on the study it was concluded that BLE technology is the most suitable for indoor-positioning in medical facilities. It is energy-efficient, it has sufficiently fast data transfer rate, good communication radius and a large range of ready-made communication equipment. It is also worth noting that most wireless medical sensors exchange data via the BLE interface.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΌΠ΅ΡΡΠΎΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΎΠ±ΡΠ΅ΠΊΡΠΎΠ² Π² Π·Π°ΠΊΡΡΡΠΎΠΌ ΠΏΠΎΠΌΠ΅ΡΠ΅Π½ΠΈΠΈ ΠΈΠ³ΡΠ°Π΅Ρ Π±ΠΎΠ»ΡΡΡΡ ΡΠΎΠ»Ρ Π²ΠΎ ΠΌΠ½ΠΎΠ³ΠΈΡ
ΡΡΠ΅ΡΠ°Ρ
Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ ΠΈ Π² ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Π΅. ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΠΈΡΡΠ΅ΠΌ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΏΠΎΠ²ΡΡΠΈΡΡ ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ ΠΎΠΊΠ°Π·Π°Π½ΠΈΡ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΠΏΠΎΠΌΠΎΡΠΈ ΠΈ ΡΠ½ΠΈΠ·ΠΈΡΡ ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΡΡΠΎ ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΡΠ΅Ρ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ ΡΠ΅Π»Π΅ΠΉ, ΠΎΠ±ΠΎΠ·Π½Π°ΡΠ΅Π½Π½ΡΡ
Π² Π³ΠΎΡΡΠ΄Π°ΡΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠ΅ Π ΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ Π€Π΅Π΄Π΅ΡΠ°ΡΠΈΠΈ "Π Π°Π·Π²ΠΈΡΠΈΠ΅ Π·Π΄ΡΠ°Π²ΠΎΠΎΡ
ΡΠ°Π½Π΅Π½ΠΈΡ". Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ. ΠΠ½Π°Π»ΠΈΠ· ΠΏΡΠΈΠΌΠ΅Π½ΠΈΠΌΠΎΡΡΠΈ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
ΡΠ°Π΄ΠΈΠΎΡΠ°ΡΡΠΎΡΠ½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΌΠ΅ΡΡΠΎΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° Π² Π·Π΄Π°Π½ΠΈΠΈ ΡΡΠ°ΡΠΈΠΎΠ½Π°ΡΠ°. ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π Ρ
ΠΎΠ΄Π΅ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΡΡΡΡΡ Π½Π°ΡΡΠ½ΡΠ΅ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΈ, ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π½ΡΠ΅ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠΌΡ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π½Π° Π±Π°Π·Π΅ ΡΠ°Π΄ΠΈΠΎΡΠ°ΡΡΠΎΡΠ½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ. ΠΡΠΏΠΎΠ»ΡΠ·ΡΠ΅ΠΌΡΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ Π²ΠΊΠ»ΡΡΠ°ΡΡ Π² ΡΠ΅Π±Ρ: β Π±ΠΈΠ±Π»ΠΈΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΏΠΎΠΈΡΠΊ; β ΠΎΡΠ±ΠΎΡ ΠΈ ΠΏΡΠΎΠ²Π΅ΡΠΊΡ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ² Ρ ΡΡΠ΅ΡΠΎΠΌ ΠΈΡ
Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΠΈ, ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΡ ΡΠ΅ΠΌΠ°ΡΠΈΠΊΠ΅ ΠΈ Π°Π²ΡΠΎΡΠΈΡΠ΅ΡΠ½ΠΎΡΡΠΈ; β Π°Π½Π°Π»ΠΈΠ· ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ² Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π΄Π΅ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΠΈ ΠΈ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π°. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π Π΅Π·ΡΠ»ΡΡΠ°Ρ Π°Π½Π°Π»ΠΈΠ·Π° ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°Π΅Ρ, ΡΡΠΎ ΡΠ°Π΄ΠΈΠΎΡΠ°ΡΡΠΎΡΠ½ΡΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡ ΠΌΠ΅ΡΡΠΎΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ ΠΎΠ±ΡΠ΅ΠΊΡΠΎΠ², ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΡ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΡΠ°Π΄ΠΈΠΎΠ²ΠΎΠ»Π½. ΠΡΠ½ΠΎΠ²Π½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΠΊ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π·Π°ΠΊΠ»ΡΡΠ°Π΅ΡΡΡ Π² ΡΠΎΠΌ, ΡΡΠΎ ΠΈΠ·-Π·Π° ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΡ ΡΠ°Π΄ΠΈΠΎΡΠΈΠ³Π½Π°Π»ΠΎΠ² ΡΠΊΠ²ΠΎΠ·Ρ ΡΡΠ΅Π½Ρ ΠΈ ΠΏΠ΅ΡΠ΅ΠΊΡΡΡΠΈΡ ΠΏΡΠΈΡ
ΠΎΠ΄ΠΈΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡ ΡΠ»ΠΎΠΆΠ½ΡΠ΅ Π²ΡΡΠΈΡΠ»ΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ Π°Π»Π³ΠΎΡΠΈΡΠΌΡ Π΄Π»Ρ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΈΡ ΠΎΠ±ΡΠ΅ΠΊΡΠ° Ρ ΡΠΎΡΠ½ΠΎΡΡΡΡ Π΄ΠΎ ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠΌΠ΅ΡΠ΅Π½ΠΈΡ. ΠΠ΅ΡΠΌΠΎΡΡΡ Π½Π° Π΄Π°Π½Π½ΡΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΠΊ, ΡΠ°Π΄ΠΈΠΎΡΠ°ΡΡΠΎΡΠ½ΡΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΌΠΎΠ³ΡΡ ΠΏΡΠΈΠΌΠ΅Π½ΡΡΡΡΡ Π΄Π»Ρ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π² ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΡΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡΡ
, ΡΠ°ΠΊ ΠΊΠ°ΠΊ ΠΎΠ½ΠΈ ΠΏΡΠΎΡΡΡ Π² ΡΠ°Π·Π²Π΅ΡΡΡΠ²Π°Π½ΠΈΠΈ ΠΈ ΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°Π½ΠΈΠΈ ΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΡΡΡΡ Π² Π³ΠΎΡΠΎΠ²ΡΡ
ΠΊΠΎΠΌΠΌΠ΅ΡΡΠ΅ΡΠΊΠΈΡ
ΡΠ΅ΡΠ΅Π½ΠΈΡΡ
. ΠΡΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡ ZigBee, ΡΠ°ΠΊ ΠΊΠ°ΠΊ ΠΎΠ½Π° Π½Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΎΡΡΠ»Π΅ΠΆΠΈΠ²Π°ΡΡ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΠ΅ ΠΎΠ±ΡΠ΅ΠΊΡΡ Π² ΡΠ΅ΠΆΠΈΠΌΠ΅ ΡΠ΅Π°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ. ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ° ΠΎΡΠ½ΠΎΠ²Π΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ΄Π΅Π»Π°Π½ Π²ΡΠ²ΠΎΠ΄ ΠΎ ΡΠΎΠΌ, ΡΡΠΎ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡ BLE ΡΠ²Π»ΡΠ΅ΡΡΡ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ΡΡΠ΅ΠΉ Π΄Π»Ρ ΠΏΠΎΠ·ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π² ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΡΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡΡ
, ΡΠ°ΠΊ ΠΊΠ°ΠΊ ΠΎΠ½Π° ΠΎΠ±Π»Π°Π΄Π°Π΅Ρ Π½ΠΈΠ·ΠΊΠΈΠΌ ΡΠ½Π΅ΡΠ³ΠΎΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΠ΅ΠΌ, Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΠΊΠΎΡΠΎΡΡΡΡ ΠΏΠ΅ΡΠ΅Π΄Π°ΡΠΈ Π΄Π°Π½Π½ΡΡ
, Ρ
ΠΎΡΠΎΡΠΈΠΌ ΡΠ°Π΄ΠΈΡΡΠΎΠΌ ΡΠ²ΡΠ·ΠΈ ΠΈ Π±ΠΎΠ»ΡΡΠΈΠΌ Π²ΡΠ±ΠΎΡΠΎΠΌ Π³ΠΎΡΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΎΠ±ΠΎΡΡΠ΄ΠΎΠ²Π°Π½ΠΈΡ. Π’Π°ΠΊΠΆΠ΅ ΡΡΠΎΠΈΡ ΠΎΡΠΌΠ΅ΡΠΈΡΡ, ΡΡΠΎ Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²ΠΎ Π±Π΅ΡΠΏΡΠΎΠ²ΠΎΠ΄Π½ΡΡ
ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
Π΄Π°ΡΡΠΈΠΊΠΎΠ² ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΡΡ ΠΎΠ±ΠΌΠ΅Π½ Π΄Π°Π½Π½ΡΠΌΠΈ ΡΠ΅ΡΠ΅Π· ΠΈΠ½ΡΠ΅ΡΡΠ΅ΠΉΡ BLE
ΠΡΠ΅Π½ΠΊΠ° Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΠΌΠ°ΡΡ-ΡΡΠ΅ΠΊΠ΅ΡΠΎΠ² Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ ΡΠΈΡΡΠ΅ΠΌ Π΄Π»Ρ ΡΠ΄Π°Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π° ΠΎΠ±ΡΠ΅Π³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π² ΡΠ΅ΠΆΠΈΠΌΠ΅ ΡΠ΅Π°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ
Introduction. The development of telemedicine systems intended to remotely monitor the health status of patients constitutes one of the most promising areas of contemporary science. Particularly relevant is the use of such systems to track the health of surgically treated patients. Since such patients are mobile, sensors measuring vital signs should not cause any discomfort in regular use. Thus, wearable smart trackers can be used for these purposes.Aim. The paper aims to study the possibility of using smart trackers in a telemedicine system for monitoring patient health.Materials and methods. In the study, a series of measurements was performed using GSMIN WR 41 smart bracelets in order to estimate their accuracy when measuring pulse, blood pressure, and oxygen saturation for different research subjects at rest and during intense physical exercises. In addition, the average measurement interval of the smart bracelet was determined; the operation of the smart bracelet in the telemedicine system for monitoring vital signs was considered.Results. The studies show that an average error in the measurement of vital signs (except for systolic pressure) using the smart bracelet does not exceed 10 %. In order to avoid the high error in measuring systolic pressure, an algorithm for assessing the general health of patients was developed. In addition, it is shown that the smart bracelet can detect an abrupt change in the vital signs of patients, with the average time of their measurement and data transmission to the server of the telemedicine system coming to 45 seconds.Conclusion. The study results indicate that smart bracelets can be used to remotely monitor the health of patients in real-time. These findings are confirmed by the telemedicine system designed on the basis of the smart bracelets considered in the paper.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠ΄Π½ΠΎΠΉ ΠΈΠ· ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΠΎΠ±Π»Π°ΡΡΠ΅ΠΉ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ Π½Π°ΡΠΊΠΈ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ° ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΠΈΡΡΠ΅ΠΌ, Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΡΡ
Π½Π° ΡΠ΄Π°Π»Π΅Π½Π½ΡΠΉ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ². ΠΡΠΎΠ±Π΅Π½Π½ΠΎ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠΌ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ°ΠΊΠΈΡ
ΡΠΈΡΡΠ΅ΠΌ Π΄Π»Ρ ΡΠ»Π΅ΠΆΠ΅Π½ΠΈΡ Π·Π° ΡΠΎΡΡΠΎΡΠ½ΠΈΠ΅ΠΌ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΠΏΠ΅ΡΠ΅Π½Π΅ΡΡΠΈΡ
Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π°. Π’Π°ΠΊΠΈΠ΅ ΠΏΠ°ΡΠΈΠ΅Π½ΡΡ ΠΎΠ±Π»Π°Π΄Π°ΡΡ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΡΡ, Π² ΡΠ²ΡΠ·ΠΈ Ρ ΡΡΠΈΠΌ Π΄Π°ΡΡΠΈΠΊΠΈ, ΠΈΠ·ΠΌΠ΅ΡΡΡΡΠΈΠ΅ ΠΆΠΈΠ·Π½Π΅Π½Π½ΡΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ, Π½Π΅ Π΄ΠΎΠ»ΠΆΠ½Ρ Π΄ΠΎΡΡΠ°Π²Π»ΡΡΡ Π΄ΠΈΡΠΊΠΎΠΌΡΠΎΡΡΠ° ΠΏΡΠΈ ΠΏΠΎΡΡΠΎΡΠ½Π½ΠΎΠΌ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠΈ. Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΡΠ°ΠΊΠΈΡ
Π΄Π°ΡΡΠΈΠΊΠΎΠ² Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡ Π½ΠΎΡΠΈΠΌΡΠ΅ ΡΠΌΠ°ΡΡ-ΡΡΠ΅ΠΊΠ΅ΡΡ.Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ. ΠΠ·ΡΡΠΈΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΡΠΌΠ°ΡΡ-ΡΡΠ΅ΠΊΠ΅ΡΠΎΠ² Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π° ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π ΡΠ°ΠΌΠΊΠ°Ρ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π½Π° Π±Π°Π·Π΅ ΡΠΌΠ°ΡΡ-Π±ΡΠ°ΡΠ»Π΅ΡΠΎΠ² ΠΌΠΎΠ΄Π΅Π»ΠΈ GSMIN WR 41 ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΡΡΡ ΡΠ΅ΡΠΈΡ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΠΉ Π΄Π»Ρ ΠΎΡΠ΅Π½ΠΊΠΈ ΡΠΎΡΠ½ΠΎΡΡΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΏΡΠ»ΡΡΠ°, Π΄Π°Π²Π»Π΅Π½ΠΈΡ ΠΈ ΡΠ°ΡΡΡΠ°ΡΠΈΠΈ Π½Π° ΡΠ°Π·Π½ΡΡ
ΠΈΡΠΏΡΡΡΠ΅ΠΌΡΡ
Π² ΡΠΎΡΡΠΎΡΠ½ΠΈΠΈ ΠΏΠΎΠΊΠΎΡ ΠΈ ΠΏΡΠΈ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΠΉ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π½Π°Π³ΡΡΠ·ΠΊΠ΅. Π’Π°ΠΊΠΆΠ΅ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ΅ΡΡΡ ΡΡΠ΅Π΄Π½ΠΈΠΉ ΠΈΠ½ΡΠ΅ΡΠ²Π°Π» Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΠΉ ΡΠΌΠ°ΡΡ-Π±ΡΠ°ΡΠ»Π΅ΡΠΎΠΌ ΠΈ ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΡΡΡ ΡΡΠ½ΠΊΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΌΠ°ΡΡ-Π±ΡΠ°ΡΠ»Π΅ΡΠ° Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π° ΠΆΠΈΠ·Π½Π΅Π½Π½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΡΡΡ, ΡΡΠΎ ΠΏΠΎΠ³ΡΠ΅ΡΠ½ΠΎΡΡΡ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° ΡΠΌΠ°ΡΡ-Π±ΡΠ°ΡΠ»Π΅ΡΠΎΠΌ, Π·Π° ΠΈΡΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΡΠΈΡΡΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π΄Π°Π²Π»Π΅Π½ΠΈΡ, Π² ΡΡΠ΅Π΄Π½Π΅ΠΌ Π½Π΅ ΠΏΡΠ΅Π²ΡΡΠ°Π΅Ρ 10 %. ΠΠ»Ρ ΠΊΠΎΡΡΠ΅ΠΊΡΠΈΡΠΎΠ²ΠΊΠΈ Π²ΡΡΠΎΠΊΠΎΠΉ ΠΏΠΎΠ³ΡΠ΅ΡΠ½ΠΎΡΡΠΈ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΡ ΡΠΈΡΡΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π΄Π°Π²Π»Π΅Π½ΠΈΡ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½ Π°Π»Π³ΠΎΡΠΈΡΠΌ ΠΎΡΠ΅Π½ΠΊΠΈ ΠΎΠ±ΡΠ΅Π³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°. Π’Π°ΠΊΠΆΠ΅ Π²ΡΡΡΠ½ΠΈΠ»ΠΎΡΡ, ΡΡΠΎ ΡΠΌΠ°ΡΡ-Π±ΡΠ°ΡΠ»Π΅Ρ ΡΠΏΠΎΡΠΎΠ±Π΅Π½ ΡΠ΅Π³ΠΈΡΡΡΠΈΡΠΎΠ²Π°ΡΡ ΡΠ΅Π·ΠΊΠΎΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΆΠΈΠ·Π½Π΅Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°, Π° ΡΡΠ΅Π΄Π½Π΅Π΅ Π²ΡΠ΅ΠΌΡ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΡ ΠΈ ΠΏΠ΅ΡΠ΅Π΄Π°ΡΠΈ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ Π½Π° ΡΠ΅ΡΠ²Π΅Ρ Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΡΠΎΡΡΠ°Π²Π»ΡΠ΅Ρ Π² ΡΡΠ΅Π΄Π½Π΅ΠΌ 45 Ρ.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ½Π°Π»ΠΈΠ·ΠΈΡΡΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ, ΠΌΠΎΠΆΠ½ΠΎ Π·Π°ΠΊΠ»ΡΡΠΈΡΡ, ΡΡΠΎ ΡΠΌΠ°ΡΡ-Π±ΡΠ°ΡΠ»Π΅ΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡ Π΄Π»Ρ ΡΠ΄Π°Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π° ΡΠ΅ΠΊΡΡΠ΅Π³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° Π² ΡΠ΅ΠΆΠΈΠΌΠ΅ ΡΠ΅Π°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ. ΠΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π΅Π½ΠΈΠ΅ΠΌ Π΄Π°Π½Π½ΡΡ
Π²ΡΠ²ΠΎΠ΄ΠΎΠ² ΡΠ»ΡΠΆΠΈΡ ΡΠ΅Π»Π΅ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠ°Ρ ΡΠΈΡΡΠ΅ΠΌΠ°, ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π½Π°Ρ Π½Π° Π±Π°Π·Π΅ ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΡΡ
ΡΠΌΠ°ΡΡ-Π±ΡΠ°ΡΠ»Π΅ΡΠΎΠ²
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