304 research outputs found
Radiomorphological Parameters of the Foot Bones During the Talus Fracture Treatment Using the Ilizarov Apparatus
Background: Talus fractures are one of the most dangerous injuries leading to serious consequences. Quite a lot of treatment methods have been proposed, but the use of the Ilizarov apparatus is relatively rare. Objective: To justify the use of the Ilizarov apparatus in the talus fracture treatment by studying radiomorphological parameters of the foot bones at different stages of follow-up. Methods: We used radiography and multislice computed tomography (MSCT) in 25 patients treated for talus injuries by the Ilizarov apparatus to study radiographic and radiomorphological features of the foot bones at different stages of follow-up. We analyzed normal parameters of the foot bones forming the ankle joint in 15 patients. Results and discussion: Dynamics of talus radiomorphology during its fracture or fracture-dislocation are characterized by a gradual increase in the bone density at the union site. The local density of the talus at the fracture site gradually increased and exceeded 500 HU in 6 months. The organotypic adjustment at the union site did not end by this time, given the architecture of the talus and the biomechanics of the foot. We observed a decrease in the total densities of the talus and calcaneus during fixation by the Ilizarov apparatus and their gradual return to normal values after removal of the apparatus. Conclusions: Talus fracture treatment by transosseous osteosynthesis using the Ilizarov apparatus makes it possible to get immediate good results, especially using a configuration with hinges allowing for early mobilization of the ankle joint and loading in the early stages of treatment
Mineral and bone metabolism in patients with idiopathic scoliosis depending on the magnitude of the deformity
Objective: Analysis of the results of the study of mineral metabolism and bone formation markers in patients with idiopathic scoliosis, depending on the magnitude of the deformity.Material and methods: Based on the retrospective single‑center study in 30 patients diagnosed with scoliosis the preoperative parameters of calcium metabolism (total and ionized calcium, parathyroid hormone, 24‑hour urine calcium), phosphorus, bone formation markers (alkaline phosphatase, osteocalcin, P1NP in the blood), deoxypyridinoline in morning urine, blood levels of 25(OH)D have been analyzed. The patients were divided into 3 groups: with a deformity of 25–40 ° (group 1), 40–60 ° (group 2) and 60–80 ° (group 3) (n = 30). The mean age in all groups was 18.5 ± 4.7.Results: In patients with idiopathic scoliosis, alkaline phosphatase and P1NP significantly exceeded normal values in the first group, which indicated a more high‑turnover type of bone remodeling with a deficient level of 25(OH)D. A higher excretion of deoxypyridinoline and a decrease in phosphorus in blood in patients with a deformity of 60–80 ° suggest a violation of the ratio of the processes of synthesis and resorption in bone tissue.Conclusion: The study of mineral metabolism and all the main markers of bone formation made it possible to obtain a more complete picture of the state of metabolic processes in bone tissue, to obtain reliable data on the effect of some of them on the nature of bone remodeling and the magnitude of spinal deformity
Orthopaedic, psychological, social and philosophical aspects of achondroplasia patients treated with the Ilizarov method
Introduction Achondroplasia is the most common skeletal dysplasia with limb shortening that can be symptomatically be treated with the Ilizarov
method developed in the 20th century. Achondroplasia patients were shown to have medical and surgical possibilities for height increase with indications
being controversial, and psychological and social implications to be considered. Objective The purpose of the study was to review our own data and
reported findings on possibilities, results and complications of Ilizarov treatment of achondroplasia patients. Material and methods Outcomes of
750 achondroplasia patients treated at the Kurgan Ilizarov Center between 1976 and 2017 were reviewed. The patients’age ranged from 4 to 23 years.
Results Long-term outcomes were followed up in all the cases. Radiography was used to assess limb elongation at follow-ups and MRI, MSCT and
US were optional. Ten-to-fifteen-year follow-ups showed persisted length gain, early osteoarthritis of the hip and knee joints due to baseline articular
changes, completely restructured femur and tibia at the distraction site, normal anatomy and area of muscle cross-section, normal structure and thickness
of tibial muscles. Social and psychological profile appeared to improve. We have data from the patients who underwent limb lengthening 30 years ago.
Many of them are employed, have family and children. Conclusion The findings suggest that achondroplasia patients, a comparatively small group of
short statured people, have good reasons to feel empowered, get social support, make parents happy and contribute to the success of the country. The
Ilizarov method has turned the idea of height increase into an accomplishment for benefits of doctors and patients being an achievement of orthopaedic
world to address orthopaedic, social, psychological and philosophical issues
Методика расчёта одно- и двухярусных микрощелевых теплообменников
Наведено методику розрахунку потужності мідного і алюмінієвого теплообмінника з мікроканалами різних розмірів. Розрахунок базується на визначенні ефективності оребрення.Power was calculated for copper and aluminum heat exchanger with microchannels of different dimensions on all height of heat exchanger. The calculation is based on the calculation of the fins.Приведена методика расчёта мощности медного и алюминиевого теплообменника с микроканалами разных размеров. Расчёт основывается на определении эффективности оребрения
Biochemical blood parameters in determining the elastic properties of the vascular wall in hypertensive patients with abdominal obesity
The article describes approaches that use parameters of biochemical laboratory markers as the basis for the indirect determination of the value of a functional parameter 'pulse wave velocity*, which characterizes the stiffness of the vessel wall. Using a mathematical model of an artificial neural network makes it possible to assess the degree of deviation of the resulting stiffness of the vessel wall from the standard value. An increase in this value is determined by the defeat of the vascular wall as a target organ that helps to clarify the stage of hypertension and optimize antihypertensive therapy in hypertensive patients with abdominal obesity.В статье описаны подходы, позволяющие использовать параметры биохимических лаб раторных маркеров в качестве основы для оценки величины функционального параметра «скорость распространения пульсовой волны», характеризующего жесткость сосудистой стенки. Использование математической модели искусственной нейронной сети дает возможность оценить степень отклонения полученного показателя жесткости сосудистой стенки от нормативного значения. При повышении этого значения определяется поражение сосудистой стенки как органа-мишени, что позволяет уточнить стадию артериальной гипертонии и провести оптимизацию антигипертензивной терапии у больных артериальной гипертонией с абдоминальным ожирением
Observation of Cabibbo-suppressed two-body hadronic decays and precision mass measurement of the baryon
The first observation of the singly Cabibbo-suppressed
and decays
is reported, using proton-proton collision data at a centre-of-mass energy of
, corresponding to an integrated luminosity of , collected with the LHCb detector between 2016 and 2018. The
branching fraction ratios are measured to be
,
. In addition, using the
decay channel, the baryon
mass is measured to be , improving the
precision of the previous world average by a factor of four.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2023-011.html (LHCb
public pages
Measurement of boson production cross-section in collisions at TeV
The first measurement of the boson production cross-section at
centre-of-mass energy TeV in the forward region is reported,
using collision data collected by the LHCb experiment in year 2017,
corresponding to an integrated luminosity of . The
production cross-section is measured for final-state muons in the
pseudorapidity range . The integrated cross-section is determined to be for the di-muon invariant
mass in the range . This result and the
differential cross-section results are in good agreement with theoretical
predictions at next-to-next-to-leading order in the strong coupling.
Based on a previous LHCb measurement of the boson production
cross-section in Pb collisions at TeV, the nuclear
modification factor is measured for the first time at this
energy. The measured values are in the forward region () and
in the backward region
(), where represents the muon rapidity in
the centre-of-mass frame.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2023-010.html (LHCb
public pages
Studies of and production in and Pb collisions
The production of and mesons is studied in proton-proton and
proton-lead collisions collected with the LHCb detector. Proton-proton
collisions are studied at center-of-mass energies of and ,
and proton-lead collisions are studied at a center-of-mass energy per nucleon
of . The studies are performed in center-of-mass rapidity
regions (forward rapidity) and
(backward rapidity) defined relative to the proton beam direction. The
and production cross sections are measured differentially as a function
of transverse momentum for and , respectively. The differential cross sections are used to
calculate nuclear modification factors. The nuclear modification factors for
and mesons agree at both forward and backward rapidity, showing
no significant evidence of mass dependence. The differential cross sections of
mesons are also used to calculate cross section ratios,
which show evidence of a deviation from the world average. These studies offer
new constraints on mass-dependent nuclear effects in heavy-ion collisions, as
well as and meson fragmentation.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://lhcbproject.web.cern.ch/Publications/p/LHCb-PAPER-2023-030.html (LHCb
public pages
Observation of the decays
This paper reports the observation of the decays using proton-proton collision data collected by the
LHCb experiment, corresponding to an integrated luminosity of
. The branching fractions of these decays are measured
relative to the normalisation channel .
The meson is reconstructed in the
decay channel and the products of branching
fractions are measured to be The first uncertainty is
statistical, the second systematic, and the third arises from the uncertainty
of the branching fraction of the
normalisation channel. The last uncertainty in the result is due to
the limited knowledge of the fragmentation fraction ratio, . The
significance for the and signals is larger than
. The ratio of the helicity amplitudes which governs the angular
distribution of the decay
is determined from the data. The ratio of the - and -wave amplitudes is
found to be and its phase rad,
where the first uncertainty is statistical and the second systematic.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2023-014.html (LHCb
public pages
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