Frustrated phase separation in two-dimensional charged systems

We study phase separation frustrated by the long-range Coulomb interaction in two dimensional electronic systems with emphasys in the case of a metallic and an insulating phase. We find that two-dimensional systems are more prone to mesoscopic frustrated phase separation than the three dimensional ones.Comment: 15 pages, 11 figure

Impact of Anisotropic Birefringence on Measuring Cosmic Microwave Background Lensing

The power spectrum of cosmic microwave background lensing is a powerful tool for constraining fundamental physics such as the sum of neutrino masses and the dark energy equation of state. Current lensing measurements primarily come from distortions to the microwave background temperature field, but the polarization lensing signal will dominate upcoming experiments with greater sensitivity. Cosmic birefringence refers to the rotation of the linear polarization direction of microwave photons propagating from the last scattering surface to us, which can be induced by parity-violating physics such as axion-like dark matter or primordial magnetic fields. We find that, for an upcoming CMB-S4-like experiment, if there exists the scale-invariant anisotropic birefringence with an amplitude corresponding to the current $95\%$ upper bound, the measured lensing power spectrum could be biased by up to a factor of few at small scales, $L\gtrsim 1000$. We show that the bias scales linearly with the amplitude of the scale-invariant birefringence spectrum. The signal-to-noise of the contribution from anisotropic birefringence is larger than unity even if the birefringence amplitude decreases to $\sim 5\%$ of the current upper bound. Our results indicate that a measurement and characterization of the anisotropic birefringence is important for lensing analysis in future low-noise polarization experiments.Comment: 13 pages, 5 figures, to be submitted to PR

One-shot ultraspectral imaging with reconfigurable metasurfaces

One-shot spectral imaging that can obtain spectral information from thousands of different points in space at one time has always been difficult to achieve. Its realization makes it possible to get spatial real-time dynamic spectral information, which is extremely important for both fundamental scientific research and various practical applications. In this study, a one-shot ultraspectral imaging device fitting thousands of micro-spectrometers (6336 pixels) on a chip no larger than 0.5 cm$^2$, is proposed and demonstrated. Exotic light modulation is achieved by using a unique reconfigurable metasurface supercell with 158400 metasurface units, which enables 6336 micro-spectrometers with dynamic image-adaptive performances to simultaneously guarantee the density of spectral pixels and the quality of spectral reconstruction. Additionally, by constructing a new algorithm based on compressive sensing, the snapshot device can reconstruct ultraspectral imaging information ($\Delta\lambda$/$\lambda$~0.001) covering a broad (300-nm-wide) visible spectrum with an ultra-high center-wavelength accuracy of 0.04-nm standard deviation and spectral resolution of 0.8 nm. This scheme of reconfigurable metasurfaces makes the device can be directly extended to almost any commercial camera with different spectral bands to seamlessly switch the information between image and spectral image, and will open up a new space for the application of spectral analysis combining with image recognition and intellisense

Protective Mechanism of Humanin Against Oxidative Stress in Aging-Related Cardiovascular Diseases

Physiological reactive oxygen species (ROS) are important regulators of intercellular signal transduction. Oxidative and antioxidation systems maintain a dynamic balance under physiological conditions. Increases in ROS levels destroy the dynamic balance, leading to oxidative stress damage. Oxidative stress is involved in the pathogenesis of aging-related cardiovascular diseases (ACVD), such as atherosclerosis, myocardial infarction, and heart failure, by contributing to apoptosis, hypertrophy, and fibrosis. Oxidative phosphorylation in mitochondria is the main source of ROS. Increasing evidence demonstrates the relationship between ACVD and humanin (HN), an endogenous peptide encoded by mitochondrial DNA. HN protects cardiomyocytes, endothelial cells, and fibroblasts from oxidative stress, highlighting its protective role in atherosclerosis, ischemia–reperfusion injury, and heart failure. Herein, we reviewed the signaling pathways associated with the HN effects on redox signals, including Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2), chaperone-mediated autophagy (CMA), c-jun NH2 terminal kinase (JNK)/p38 mitogen-activated protein kinase (p38 MAPK), adenosine monophosphate-activated protein kinase (AMPK), and phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)-Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3). Furthermore, we discussed the relationship among HN, redox signaling pathways, and ACVD. Finally, we propose that HN may be a candidate drug for ACVD

Large-scale Kinetic Simulations of Colliding Plasmas within a Hohlraum of Indirect Drive Inertial Confinement Fusions

The National Ignition Facility has recently achieved successful burning plasma and ignition using the inertial confinement fusion (ICF) approach. However, there are still many fundamental physics phenomena that are not well understood, including the kinetic processes in the hohlraum. Shan et al. [Phys. Rev. Lett, 120, 195001, 2018] utilized the energy spectra of neutrons to investigate the kinetic colliding plasma in a hohlraum of indirect drive ICF. However, due to the typical large spatial-temporal scales, this experiment could not be well simulated by using available codes at that time. Utilizing our advanced high-order implicit PIC code, LAPINS, we were able to successfully reproduce the experiment on a large scale of both spatial and temporal dimensions, in which the original computational scale was increased by approximately 7 to 8 orders of magnitude. When gold plasmas expand into deuterium plasmas, a kinetic shock is generated and propagates within deuterium plasmas. Simulations allow us to observe the entire progression of a strong shock wave, including its initial formation and steady propagation. Although both electrons and gold ions are collisional (on a small scale compared to the shock wave), deuterium ions seem to be collisionless. This is because a quasi-monoenergetic spectrum of deuterium ions can be generated by reflecting ions from the shock front, which then leads to the production of neutrons with unusual broadening due to beam-target nuclear reactions. This work displays an unprecedented kinetic analysis of an existing experiment, shedding light on the mechanisms behind shock wave formation. It also serves as a reference for benchmark simulations of upcoming new simulation codes and may be relevant for future research on mixtures and entropy increments at plasma interfaces