We study phase separation frustrated by the long-range Coulomb interaction in
two dimensional electronic systems with emphasys in the case of a metallic and
an insulating phase. We find that two-dimensional systems are more prone to
mesoscopic frustrated phase separation than the three dimensional ones.Comment: 15 pages, 11 figure

Ewa Ellis

Hongbo Cai

Keitaro Mitamura

Paolo Bruzzone

Stephen C. Strom

Thomas Lehmann

Toshio Miki

English

arXiv

Hepatocyte transplantation has been proposed as a method to support patients with liver insufficiency. There are three main areas where the transplantation of isolated hepatocytes has been proposed and used for clinical therapy. Cell transplantation has been used: 1) for temporary metabolic support of patients in end-stage liver failure awaiting whole organ transplantation, 2) as a method to support liver function and facilitate regeneration of the native liver in cases of fulminant hepatic failure, and 3) in a manner similar to gene therapy, as a "cellular therapy" for patients with genetic defects in vital liver functions. We will briefly review the basic research that leads to clinical hepatocyte transplantation, the published clinical experience with this experimental technique, and some possible future uses of hepatocyte transplantation

Open Access Repository

Hepatocyte transplantation: clinical experience and potential for future use.

Hepatocyte transplantation has been proposed as a method to support patients with liver insufficiency. There are three main areas where the transplantation of isolated hepatocytes has been proposed and used for clinical therapy. Cell transplantation has been used: 1) for temporary metabolic support of patients in end-stage liver failure awaiting whole organ transplantation, 2) as a method to support liver function and facilitate regenera- tion of the native liver in cases of fulminant hepatic failure, and 3) in a manner similar to gene therapy, as a “cellular therapy” for patients with genetic defects in vital liver functions. We will briefly review the basic research that leads to clinical hepatocyte transplantation, the published clinical experience with this experimental technique, and some possible future uses of hepatocyte transplantation. In The Lancet today, Jacob Lavee and colleagues1 describe a new law recently approved by Israel’s Parliament. The law will become eff ective in January, 2010, and will grant donor-card holders priority in organ allocation, with the aim of increasing the number of organ donations and reducing the length of transplantation waiting lists

S. C. Strom

H. Cai

E. Ellis

T. Lehmann

K. Mitamura

T. Miki

BRUZZONE, Paolo

Archivio della ricerca- Università di Roma La Sapienza

HEPATOCYTE TRANSPLANTATION: CLINICAL EXPERIENCE AND POTENTIAL FOR FUTURE USE

We study phase-separation frustrated (FPS) by the long-range Coulomb interaction in two-dimensional electronic systems with emphasis to the case of a metallic and an insulating phase. In the mixed phase, the system self-organizes in terms of mesoscopic inhomogeneities of one phase hosted by the other phase. We analyze the cases of circular drops and alternating stripes. As a first approximation, we consider the density inside each inhomogeneity as constant and in some cases, we test the accuracy of this assumption by a more involved local density approximation. We find that the transition from the uniform phase to the frustrated phase-separated phase changes order depending upon its geometric arrangement. Contrary to what was found in three-dimensional systems, there is no upper bound for the size of inhomogeneities. This difference stands on the different role of the long-range Coulomb interaction and screening in two- and three-dimensional systems. We conclude that two-dimensional systems are more prone to mesoscopic FPS. Â© 2006 The American Physical Society

Frustrated phase separation in two-dimensional charged systems

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