"Wenn die Prosa abgetan ist, kann die Poesie um so lustiger gedeihen" : Goethes Lebensführung im Spiegel seiner Haushaltsbücher

Goethe lebte auf großem Fuß, das belegen seine akribisch geführten Haushaltsbücher aus der Weimarer Zeit. Großzügig war er, wenn es um die fürstliche Bewirtung seiner Gäste, seine zahlreichen Reisen und die Neuanschaffungen für seine Sammlungen ging. Bescheidener lebte er im engeren Familienkreis. Geprägt von den bürgerlichen Prinzipien seines Frankfurter Elternhauses war ihm die sorgfältige Kostenkontrolle immer ein Anliegen, die Ordnung seiner privaten Finanzwirtschaft stellte für ihn die Basis seines Lebenswerks dar

Investigation of the Current Levels of Dust-to-Binder Ratio on Durability of Asphalt Mixtures

Durability refers to the resistance of Asphalt Concrete (AC) to several forms of cracking. It is the goal of State Highway Agencies (SHAs) and local authorities alike, to maintaining adequate durability and ensure good pavement performance. Since the early 2000s, escalating asphalt binder costs have significantly increased the use of reclaimed asphalt pavement (RAP) within AC mixtures. This increase, although cost effective and environmentally conscious, has detrimentally affected AC durability. Optimization of RAP and the regulation of AC durability is currently being addressed during the design and construction of AC pavements through Quality Control (QC) and Quality Assurance (QA) testing. With that being said, AC mixtures produced in the field commonly experience a loss of durability compared to laboratory designed AC mixtures. This loss of durability is frequently thought to be attributed to mixture adjustments and material inconsistencies caused during production and can occur within agencies whose specifications do not include multiple production volumetric requirements. One volumetric requirement that is thought to significantly affect AC durability is Dust Proportion (DP). Mixture DP is notable due to its ability to effectively regulate detrimental AC mixture fines compared to current practices.The purpose of this study was to investigate current DP levels and their impact on mixture performance. AC mixture durability, as well as stability, were evaluated using the Indirect Tensile Cracking (Ideal-CT), Texas Overlay (OT), Indirect Tensile Strength (IDT), and Hamburg Wheel Track (HWTT) tests. Comparisons between field mix lab compacted (FMLC), lab mix lab compacted (LMLC), and a modified DP lab mix lab compacted (1.6 LMLC) AC mixture were analyzed. Results from this study showed that the relationship between the number of cycles till failure determined from the OT test and the CTindex determined from the Ideal-CT test were highly correlated. Mixture properties including the DP, effective binder, total binder, absorbed binder, and film thickness were also determined to significantly affect the IDT and Ideal-CT testing results. Results from this study allowed the researchers to better understand how mixture fluctuations during AC production and deviations from the mixture design affected AC performance. A DP specification and specification language regarding other volumetric properties and performance tests were recommended based on the findings of this study. This research shall serve as a guide to help other local and state regulatory agencies with AC durability concerns

The Effects of Increasing Running Speed on vGRF and Asymmetry

Biomechanical and physiological parameters related to running performance are usually studied separately. However, evaluating both aspects together could be beneficial in improving athletic performance. The purpose of this study was to observe the change in peak vGRF and asymmetry as speed increases, while observing physiological responses during a O2maxtest. Data from athlete monitoring of 12 cross-country and triathlon athletes were analyzed. The athlete monitoring protocol included three unweighted countermovement jumps and a O2maxtest performed by the athletes. The athletes had an average O2maxof 53.4 ± 7.7 mL/kg/min, while their average vGRF asymmetry throughout the O2maxtestwas 1.38 ± 0.68%. A strong, positive correlation was found between average vGRF and average blood lactate (r=0.93), indicating that as vGRF increased so did blood lactate. It was concluded that physiological and biomechanical parameters are related in athletic performance. Therefore, athlete monitoring should include analysis of both physiological and biomechanical parameters in order to form a more well-rounded analysis of athlete performance

Informe previo de los estudios geoquímicos y mineralógicos del yacimiento estratiforme de W de Mina Susana (Santa Comba, NO de España) con una contribución a la prospección química

[Resumen] La mineralización estratiforme de scheelita está ligada a una serie de metasedimentitas ricas en anfiboles que se encuentra como "100.tejón" en un granito estéril de dos micas. Para la prospección geoquímica de otros "lentejones", Cr, Co, Ni, Cu y Zn, que están relacionados con los sulfuros y las concentraciones lenticulares de anfiboles en las metasedimentitas, pueden servir como elementos precursores.[Resumen] La mineralización estratiforme de scheelita está ligada a una serie de metasedimentitas ricas en anfiboles que se encuentra como "100.tejón" en un granito estéril de dos micas. Para la prospección geoquímica de otros "lentejones", Cr, Co, Ni, Cu y Zn, que están relacionados con los sulfuros y las concentraciones lenticulares de anfiboles en las metasedimentitas, pueden servir como elementos precursores.[Abstract] The stratiform scheelite mineralization is bounded to a suite of amphibole-rich metasediments lying lenticularly in a two-mica granite. Cr, Co, Ni, Cu and Zn are concentrated in sulfides and amphiboles of the metasediments and can be used as indicator elements in geochemical exploration for other lentils of metasediments[Zusammenfassung] Die stratiforme Scheelit-Vererzung ist aneine Serie amphibolreicher Metasedimentitegebunden, die als Linse in einem tauben Zweiglimmergrani t ansteht. Bei der geochemischen Prospektion weiterer Linsen lassen sich Cr, Co, Ni, Cu und Zn, die in den Sulfiden und Amphibolen der Metasedimentite konzentriert sind, als Pfadfinderelemente verwende

Distance Labs

This capstone paper is a compilation of the information we discovered during our research on the topic of distance lab environments for online computing courses. We provide our research, our findings, and our supporting evidence to answer the following question: How can La Salle University deliver a comparable hands-on learning experience for its online student population without requiring the students to attend on-campus? Initially, our research suggests a solution for the Economic Crime Forensics (ECF) courses; however, it will benefit all lab related computing courses at La Salle University. This paper will show: (a) that the goal of using a distance lab for the Economic Crime Forensics (ECF) courses is obtainable, and how it will benefit students by completing the lab assignments in the computing courses; (b) our literature review; (c) and our research findings from several sources. Our research includes discussions with La Salle University Faculty; sample sessions with three public cloud computing services: CloudShare ProPlus, Skytap, and Amazon Web Services (AWS); and implementations from schools using a private cloud service on-campus with the IBM Virtual Computing Lab Initiative (VCL) Model including how Higher Education is using commercially available virtualization software from VMWare (VCloud) on top of their own architecture

Inhibition of 11β-hydroxysteroid dehydrogenase and its effect on epithelial sodium transport

Recently the hitherto accepted concept of mechanism(s) of interaction between (cortico)steroid hormones and target cells has been modified and extended. Thus, as proposed in the case of estrogen receptors, unoccupied and hormone occupied receptors exclusively reside in the nuclear compartment [1], In intact cells there is no translocation of hormone-receptor complex from cytoplasm to nuclei [2]. In enucleated preparations unoccupied receptors could be localized in the nuclear compartment.The second notion which has attracted attention is the presence of corticosteroid metabolizing enzymes in many target tissues. It is most likely that such enzymes are included in the control of the cellular response to corticosteroid hormone signals [3, 4]. An important enzyme system, 11β-hydroxy-steroid-dehydrogenase (11-HSD, E.C. 1.1.1.146), has recently been implicated in mediating mineralocorticoid specificity of corticosteroid receptors [5–7].1 It is this concept we address in the present paper. In experiments with rat renal microsomal fractions we have tested the inhibitory effects of steroidal inhibitors on both the apparent oxidative and reductive activity of 11-HSD. Subsequently, isolated rat rectal epithelium has been used in the attempt to test whether or not inhibition of 11-HSD might modify the apparent mineralocorticoid activity of the endogenous rat glucocorticoid corticosterone