4,559 research outputs found

    Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.

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    In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs) and synaptonemal complexes. Here, we show that levels of ESCO2, acSMC3, and the pro-cohesion factor sororin increase on meiotic chromosomes as homologs synapse. These proteins are less abundant on the largely unsynapsed sex chromosomes, whose sister chromatid cohesion appears weaker throughout the meiotic prophase. Using three distinct conditional Esco2 knockout mouse strains, we demonstrate that ESCO2 is essential for male gametogenesis. Partial depletion of ESCO2 in prophase I spermatocytes delays chromosome synapsis and further weakens cohesion along sex chromosomes, which show extensive separation of AEs into single chromatids. Unsynapsed regions of autosomes are associated with the sex chromatin and also display split AEs. This study provides the first evidence for a specific role of ESCO2 in mammalian meiosis, identifies a particular ESCO2 dependence of sex chromosome cohesion and suggests support of autosomal synapsis by acSMC3-stabilized cohesion

    Strange matter in core-collapse supernovae

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    We discuss the possible impact of strange quark matter on the evolution of core-collapse supernovae with emphasis on low critical densities for the quark-hadron phase transition. For such cases the hot proto-neutron star can collapse to a more compact hybrid star configuration hundreds of milliseconds after core-bounce. The collapse triggers the formation of a second shock wave. The latter leads to a successful supernova explosion and leaves an imprint on the neutrino signal. These dynamical features are discussed with respect to their compatibility with recent neutron star mass measurements which indicate a stiff high density nuclear matter equation of state.Comment: 8 pages, 3 figures, Invited talk at the "Strangeness in Quark Matter" conference, 18-24 September 2011, Polish Academy of Arts and Sciences, Cracow, Polan

    Experimental quantum verification in the presence of temporally correlated noise

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    Growth in the complexity and capabilities of quantum information hardware mandates access to practical techniques for performance verification that function under realistic laboratory conditions. Here we experimentally characterise the impact of common temporally correlated noise processes on both randomised benchmarking (RB) and gate-set tomography (GST). We study these using an analytic toolkit based on a formalism mapping noise to errors for arbitrary sequences of unitary operations. This analysis highlights the role of sequence structure in enhancing or suppressing the sensitivity of quantum verification protocols to either slowly or rapidly varying noise, which we treat in the limiting cases of quasi-DC miscalibration and white noise power spectra. We perform experiments with a single trapped 171^{171}Yb+^{+} ion as a qubit and inject engineered noise (∝σz\propto \sigma^z) to probe protocol performance. Experiments on RB validate predictions that the distribution of measured fidelities over sequences is described by a gamma distribution varying between approximately Gaussian for rapidly varying noise, and a broad, highly skewed distribution for the slowly varying case. Similarly we find a strong gate set dependence of GST in the presence of correlated errors, leading to significant deviations between estimated and calculated diamond distances in the presence of correlated σz\sigma^z errors. Numerical simulations demonstrate that expansion of the gate set to include negative rotations can suppress these discrepancies and increase reported diamond distances by orders of magnitude for the same error processes. Similar effects do not occur for correlated σx\sigma^x or σy\sigma^y errors or rapidly varying noise processes, highlighting the critical interplay of selected gate set and the gauge optimisation process on the meaning of the reported diamond norm in correlated noise environments.Comment: Expanded and updated analysis of GST, including detailed examination of the role of gauge optimization in GST. Full GST data sets and supplementary information available on request from the authors. Related results available from http://www.physics.usyd.edu.au/~mbiercuk/Publications.htm

    EROs found behind lensing clusters: II.Empirical properties, classification, and SED modelling based on multi-wavelength observations

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    We study the properties and nature of extremely red galaxies (ERO, R-K>5.6) found behind two lensing clusters and compare them with other known galaxy populations. New HST/ACS observations, Spitzer IRAC and MIPS, and Chandra/ACIS observations of the two lensing clusters Abell 1835 and AC114 contemplate our earlier optical and near-IR observations and have been used to study extremely red objects (EROs) in these deep fields. We have found 6 and 9 EROs in Abell 1835 and AC114. Several (7) of these objects are undetected up to the I and/or z band, and are hence ``optical'' drop-out sources. The photometric redshifts of most of our sources (80%) are z~0.7-1.5. According to simple colour-colour diagrams the majority of our objects would be classified as hosting old stellar populations. However, there are clear signs of dusty starbursts for several among them. These objects correspond to the most extreme ones in R-K colour. We estimate a surface density of (0.97+-0.31) arcmin-2 for EROs with (R-K>5.6) at K<20.5. Among our 15 EROs 6 (40 %) also classify as distant red galaxies (DRGs). 11 of 13 EROs with available IRAC photometry also fulfil the selection criteria for IRAC selected EROs (IEROs) of Yan et al. (2004). SED modelling shows that ~ 36 % of the IEROs in our sample are luminous or ultra-luminous infrared galaxies ((U)LIRG). Some very red DRGs are found to be very dusty starbursts, even (U)LIRGs, as also supported by their mid-IR photometry. No indication for AGNs is found, although faint activity cannot be excluded for all objects. From mid-IR and X-ray data 5 objects are clearly classified as starbursts. The derived properties are quite similar to those of DRGs and IEROs, except for 5 extreme objects in terms of colours, for which a very high extinction (Av>3) is found.Comment: 20 pages, 10 figures, accepted for publication in A&

    Pushing 1D CCSNe to explosions: model and SN 1987A

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    We report on a method, PUSH, for triggering core-collapse supernova explosions of massive stars in spherical symmetry. We explore basic explosion properties and calibrate PUSH such that the observables of SN1987A are reproduced. Our simulations are based on the general relativistic hydrodynamics code AGILE combined with the detailed neutrino transport scheme IDSA for electron neutrinos and ALS for the muon and tau neutrinos. To trigger explosions in the otherwise non-exploding simulations, we rely on the neutrino-driven mechanism. The PUSH method locally increases the energy deposition in the gain region through energy deposition by the heavy neutrino flavors. Our setup allows us to model the explosion for several seconds after core bounce. We explore the progenitor range 18-21M⊙_{\odot}. Our studies reveal a distinction between high compactness (HC) and low compactness (LC) progenitor models, where LC models tend to explore earlier, with a lower explosion energy, and with a lower remnant mass. HC models are needed to obtain explosion energies around 1 Bethe, as observed for SN1987A. However, all the models with sufficiently high explosion energy overproduce 56^{56}Ni. We conclude that fallback is needed to reproduce the observed nucleosynthesis yields. The nucleosynthesis yields of 57−58^{57-58}Ni depend sensitively on the electron fraction and on the location of the mass cut with respect to the initial shell structure of the progenitor star. We identify a progenitor and a suitable set of PUSH parameters that fit the explosion properties of SN1987A when assuming 0.1M⊙_{\odot} of fallback. We predict a neutron star with a gravitational mass of 1.50M⊙_{\odot}. We find correlations between explosion properties and the compactness of the progenitor model in the explored progenitors. However, a more complete analysis will require the exploration of a larger set of progenitors with PUSH.Comment: revised version as accepted by ApJ (results unchanged, text modified for clarification, a few references added); 26 pages, 20 figure

    Manifolds associated with (Z2)n(Z_2)^n-colored regular graphs

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    In this article we describe a canonical way to expand a certain kind of (Z2)n+1(\mathbb Z_2)^{n+1}-colored regular graphs into closed nn-manifolds by adding cells determined by the edge-colorings inductively. We show that every closed combinatorial nn-manifold can be obtained in this way. When n≀3n\leq 3, we give simple equivalent conditions for a colored graph to admit an expansion. In addition, we show that if a (Z2)n+1(\mathbb Z_2)^{n+1}-colored regular graph admits an nn-skeletal expansion, then it is realizable as the moment graph of an (n+1)(n+1)-dimensional closed (Z2)n+1(\mathbb Z_2)^{n+1}-manifold.Comment: 20 pages with 9 figures, in AMS-LaTex, v4 added a new section on reconstructing a space with a (Z2)n(Z_2)^n-action for which its moment graph is a given colored grap

    Quantum simulation of the Klein paradox with trapped ions

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    We report on quantum simulations of relativistic scattering dynamics using trapped ions. The simulated state of a scattering particle is encoded in both the electronic and vibrational state of an ion, representing the discrete and continuous components of relativistic wave functions. Multiple laser fields and an auxiliary ion simulate the dynamics generated by the Dirac equation in the presence of a scattering potential. Measurement and reconstruction of the particle wave packet enables a frame-by-frame visualization of the scattering processes. By precisely engineering a range of external potentials we are able to simulate text book relativistic scattering experiments and study Klein tunneling in an analogue quantum simulator. We describe extensions to solve problems that are beyond current classical computing capabilities.Comment: 3 figures, accepted for publication in PR
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