Energy Management through Bio-gas Based Electricity Generation System during Load Shedding in Rural Areas

The scarcity of energy especially electrical energy is an acute problem and hinders the modern economic development of a country. Most of the time only a small percentage of peoples have access to use continuous electricity supply. But in this modern era, all types of arena like economies, households and companies have extensive demand for electricity which is due to industrialization, extensive urbanization, population growth, rising standard of living and modernization of the agricultural sector of a country. Electricity generation from bio-gas plant through cowdungs of a dairy firm can mitigate the electricity demand to some extends in rural areas, where biogas plant will act act as a backup supply especially during load shedding. This research paper proposed an electricity generation system from bio-gas, which can work as a secondary source of the electricity for all electrical appliances of a particular area in a cost effective manner

Low Electric Treatment activates Rho GTPase via Heat Shock Protein 90 and Protein Kinase C for Intracellular Delivery of siRNA

Low electric treatment (LET) promotes intracellular delivery of naked siRNA by altering cellular physiology. However, which signaling molecules and cellular events contribute to LET-mediated siRNA uptake are unclear. Here, we used isobaric tags in relative and absolute quantification (iTRAQ) proteomic analysis to identify changes in the levels of phosphorylated proteins that occur during cellular uptake of siRNA promoted by LET. iTRAQ analysis revealed that heat shock protein 90 (Hsp90)α and myristoylated alanine-rich C-kinase substrate (Marcks) were highly phosphorylated following LET of NIH 3T3 cells, but not untreated cells. Furthermore, the levels of phosphorylated Hsp90α and protein kinase C (PKC)γ were increased by LET both with siRNA and liposomes having various physicochemical properties used as model macromolecules, suggesting that PKCγ activated partly by Ca2+ influx as well as Hsp90 chaperone function were involved in LET-mediated cellular siRNA uptake. Furthermore, LET with siRNA induced activation of Rho GTPase via Hsp90 and PKC, which could contribute to cellular siRNA uptake accompanied by actin cytoskeleton remodeling. Collectively, our results suggested that LET-induced Rho GTPase activation via Hsp90 and PKC would participate in actin-dependent cellular uptake of siRNA

Iontophoresis of Biological Macromolecular Drugs

Over the last few decades, biological macromolecular drugs (e.g., peptides, proteins, and nucleic acids) have become a significant therapeutic modality for the treatment of various diseases. These drugs are considered superior to small-molecule drugs because of their high specificity and favorable safety profiles. However, such drugs are limited by their low oral bioavailability and short half-lives. Biological macromolecular drugs are typically administrated via invasive methods, e.g., intravenous or subcutaneous injections, which can be painful and induce needle phobia. Noninvasive transdermal delivery is an alternative administration route for the local and systemic delivery of biological macromolecular drugs. However, a challenge with the noninvasive transdermal delivery of biological macromolecular drugs is the outermost layer of the skin, known as the stratum corneum, which is a physical barrier that restricts the entry of extraneous macromolecules. Iontophoresis (IP) relies on the application of a low level of electricity for transdermal drug delivery, in order to facilitate the skin permeation of hydrophilic and charged molecules. The IP of several biological macromolecular drugs has recently been investigated. Herein, we review the IP-mediated noninvasive transdermal delivery of biological macromolecular drugs, their routes of skin permeation, their underlying mechanisms, and their advance applications

Collaborative-based web recommender system for community-driven homestay programmes

A Homestay Programme (HP) is a kind of tourism initiative where local residents welcome tourists to stay and interact with them and experience the community’s daily activities and culture, including an option for lodging. The effects of HPs on the community are reflected in the development of the economy, social capital, infrastructure and environment. Hence, a HP promotes community-based tourism (CBT) and acts as a catalyst for rural community development. Most HPs are located in the rural areas, and thus, are directly linked to showcasing the various Malaysian cultures. Although homestay tourism is a growing industry in developing countries, there are some challenges faced in operating the Malaysian HPs since this CBT does not seem to be flourishing in a similar manner as the other tourism initiatives. All of these challenges have led to the main cause that is, lack of promotion and marketing due to the inability of homestay operators to utilize technology. Therefore, to overcome this, an enhanced Collaborative-Based Web Recommender (CBWR) system that meets certain criteria for an effective and efficient homestay service delivery is developed based on the user and item approach. This CBWR system acts as a database network that serves as an intermediary between users (visitors) and the service providers, who are the HP operator. Furthermore, this CBWR can also create a partnership between the homestay database and the homestay recommender website by capturing the users’ details and storing it, which is done by the profiler. Consequently, the profiler recommends several websites that suit to the user’s request. All these operations are carried out simultaneously to boost the functions of the CBWR system. Hence, this research contributes to the development of a specific unique web database and a CBWR system, which is adopted from collaborative algorithm. In addition, the CBWR system provides a supportive recommender algorithm which is carried out in a web enabling environment in real time. This enables users to find the available personalized website and unique HPs with their signature products and services

Factors affecting cryptocurrency adoption in digital market of Malaysia

Cryptocurrency plays an important role in today's digital currency environment. Improving cryptocurrency adoption is important for consumers and practitioners, as it improves understanding, enhances behavior, attitude, trust, and increases satisfaction. Though the lack of cryptocurrency adoption is a significant issue that arises in the digital market, cryptocurrency adoption is crucial to the support of technology capability facilitated with appropriate behavioral intention too. Considering the fact, this study intended to investigate the impact of cryptocurrency adoption in the digital market in Malaysia. This empirical study examined the role of trust (TR), social influence (SI), cryptocurrency transaction transparency (CTT), technology awareness (TA), facilitating conditions (FC), performance expectancy (PE), attitude (AT), customer satisfaction on behavioral intention (BI) and cryptocurrency adoption (CA). The study also intended to examine the role of behavioral intention as a mediator in the context of cryptocurrency adoption. In line with the research objectives, systematic random sampling was used in this study. Cross-sectional data were collected using a questionnaire at the cryptocurrency consumer of Malaysia, which produced a total of 349 usable responses. The study employed Partial Least Squares Structural Equation Modelling (PLS-SEM) for data analysis. Findings o the study revealed that TR, SI, CTT, TA, and FC positively affect CA (dependent variable) through the mediation of behavioral intention (BI) in Malaysia's digital market. On the other hand, PE, AT, and CS negatively affect cryptocurrency adoption in Malaysia's digital market. Future researchers may replicate the study in different countries in a different industry context and integrate similar constructs to broaden the current body of knowledge

La relación entre el tipo de cambio, los términos de intercambio y el empleo en Turquía

The objective of this paper is to analyze the impact of real exchange rate (RER) on employment and real wage using quarterly disaggregated data (ISIC Rev 4 classification) composed of 19 industries in Turkey from 2010 to 2017. This study employed the Fixed Effect Model, where industry-specific effects are used to control heterogeneity within the industry. The results reflect that currency appreciation negatively affects employment, though insignificant, whereas it has a remarkably positive impact on real wage. Although the terms of trade have no visible impact on employment and real wages, the study uniquely finds that the effects of the larger industries on employment are distinctly adverse. Nevertheless, the interaction between currency appreciation and the top 25 per cent larger industries indicates a moderate increase in employment. The findings reflect that the appreciation of the domestic currency causes employment to decrease at the industry level. The originality of this paper includes the effects of the terms of trade and interaction with currency appreciation in larger industries using the Fixed Effect Model approach.El objetivo de este artículo es analizar el impacto del tipo de cambio real (TCR) en el empleo y el salario real utilizando datos desagregados trimestrales (clasificación ISIC Rev 4) compuestos por 19 industrias en Turquía de 2010 a 2017. Se empleó un modelo de efectos fijos, donde los efectos específicos de la industria se utilizan para controlar la heterogeneidad dentro de aquella. Los resultados reflejan que la apreciación de la moneda afecta negativamente al empleo, aunque de manera insignificante, mientras que tiene un impacto notablemente positivo en el salario real. Aunque los términos de intercambio no tienen un impacto visible en el empleo y los salarios reales, el estudio encuentra de manera única que los efectos de las industrias más grandes en el empleo son claramente adversos. No obstante, la interacción entre la apreciación de la moneda y el 25 % de las principales industrias más grandes indica un aumento moderado del empleo. Los hallazgos reflejan que la apreciación de la moneda nacional hace que el empleo disminuya en la industria. La originalidad de este documento incluye los efectos de los términos de intercambio y la interacción con la apreciación de la moneda en industrias más grandes utilizando el enfoque del modelo de efectos fijos

Relationship between Personality Traits of the Urban Poor Concerning Solid Waste Management and Household Income and Education

This study analyzes the relationship between knowledge, attitude, and behaviour of the urban poor householders concerning solid waste management systems and monthly household income and education. To attain the objective, the study employed statistical techniques such as t-tests of equality of means, one-way ANOVA, chi-squared „likelihood ratio“ test and simple descriptive statistics. The findings show that the urban poor communities with low income and education have been proven to behave in ways matching with and conducive to environment-friendly solid waste management, for instance, by practicing recycling and waste source reduction. This study also proves that the urban low-income communities generally have a very proactive role from a sound environmental management perspective, as they are the main recyclers and source-reducers of solid waste. The study suggests that policies should be formulated to focus on promoting knowledge, education, skills, and empowerment of the urban poor as means of promoting their living conditions

Wave Retail Banking Effect on Customer Satisfaction in Retail Supply Chain in Bangladesh

Abstract-Purpose: The purpose of this study is a clarification of changes of supply chain management (SCM) in public organizations and the nature of change management (CM). The paper also examines and demonstrate the trust influencing CM in technology adoption in Bangladesh pubic organizations. The aim of this paper is, consequently, to identify precarious success factors for CM. Theory: In this study we focus on the adoption of technology such as the Technology Acceptance Model (TAM), highlighted the need to broaden the scope of theoretical mechanisms. Method: In this study, we obtained the empirical data necessary to validate the theoretical framework. In total of 460 self-administered questionnaires were used to derive public sector responses in Bangladesh in their perceptions of trust and aspects of change management. Originality: This study an outline of CM in TA projects is recognized based on the literature review and empirical evidence. Significance: This study will enhance the service and management of public organization. Besides that, it will provide quality service for public organization. Finally, it will introduce technology supply chain in organization management. Outline: the paper concludes with a presentation of the study’s, framework and contributions as well as the stream of upcoming research

Challenges of Warehouse Operations: A Case Study in Retail Supermarket

The research represents a case study on Bangladesh retail supermarket. The study demonstrates the intricacies of warehouse management practice. It elaborates the dynamics of retail supply chain and the spiral affects how warehouse can play a significant role. In addition to this, the study identifies external factors, market trends, and possible barriers which influence the overall performance of warehouse operation. The paper is based on secondary data that encompassed three major retail chains in Bangladesh. The paper also reveals opportunities to improve warehouse performances in terms of planning, design and operation. The authors demonstrate some recommendations for industry practitioners to achieve a higher level of productivity in warehouse managemen