84 research outputs found

    Proceso de diseño en red de guías docentes basadas en la nueva configuración del crédito en el segundo curso de la Diplomatura en Trabajo Social de la Universidad de Alicante

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    En esta comunicación, los profesores y profesoras que elaboraron la Memoria Final del Trabajo de la Red dan cuenta sumariamente del trabajo realizado para el diseño de nuevas Guías Docentes por la Red de Investigación en Docencia Universitaria “Red de Estudio de la Docencia de Calidad en Trabajo Social. REDCATS-Segundo curso”, constituida en el marco del Programa de Redes de Investigación en Docencia Universitaria (I.C.E.) durante el curso 2003-2004 en la Universidad de Alicante. El énfasis de la comunicación está puesto en el proceso seguido por la red para la adaptación de las programaciones docentes y el diseño de las nuevas Guías docentes de las asignaturas implicadas, de acuerdo con los criterios de convergencia educativa europea y la concepción actual de los créditos ECTS. Este proceso no ha estado exento de incidencias, que recogemos como dificultadores y facilitadores principales que han sido encontrados en dicho proceso de diseño de las Guías Docentes. Por último, el trabajo concluye con una serie de propuestas de mejora para el futuro.In this paper, the authors, professors of Alicante’s University, give account of the work made within the framework of the Program of Research Networks on University Teaching (I.C.E.) during 2003-2004 academic year in order to design new Educational Guides (Syllabus). The authors are members of the Research Network on University Teaching "Red de Estudio de la Docencia de Calidad en Trabajo Social. REDCATS-Segundo curso". The emphasis of the paper is to put on the process followed by the network for the adaptation of the educational programmes and the design of the new educational guides, in agreement with the criteria of European Educative Convergence and the present conception of ECTS credits. This process does not have been free of incidences, that we gather like main obstacles and facilities that the authors have been found in this process. Finally, the work concludes with a series of proposals of improvement for the future

    Proceso de diseño en red de guías docentes basadas en la nueva configuración del crédito en el segundo curso de la diplomatura en trabajo social de la Universidad de Alicante

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    Proceso de diseño en red de guías docentes basadas en la nueva configuración del crédito en el segundo curso de la diplomatura en trabajo social de la Universidad de Alicant

    Gamma-ray Astrophysics in the MeV Range: the ASTROGAM Concept and Beyond

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    The energy range between about 100 keV and 1 GeV is of interest for a vast class of astrophysical topics. In particular, (1) it is the missing ingredient for understanding extreme processes in the multi-messenger era; (2) it allows localizing cosmic-ray interactions with background material and radiation in the Universe, and spotting the reprocessing of these particles; (3) last but not least, gamma-ray emission lines trace the formation of elements in the Galaxy and beyond. In addition, studying the still largely unexplored MeV domain of astronomy would provide for a rich observatory science, including the study of compact objects, solar- and Earth-science, as well as fundamental physics. The technological development of silicon microstrip detectors makes it possible now to detect MeV photons in space with high efficiency and low background. During the last decade, a concept of detector ("ASTROGAM") has been proposed to fulfil these goals, based on a silicon hodoscope, a 3D position-sensitive calorimeter, and an anticoincidence detector. In this paper we stress the importance of a medium size (M-class) space mission, dubbed "ASTROMEV", to fulfil these objectives

    Experiencia de aplicación de guías docentes adaptadas a los criterios de convergencia educativa en educación superior para el segundo curso de la Diplomatura de Trabajo Social

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    La red “Red de Docencia de Calidad en Trabajo Social (REDCATS-Segundo curso)”, constituida en el curso 2003-2004 para diseñar las guías docentes de las asignaturas de segundo curso de la Diplomatura de Trabajo Social, tuvo continuidad durante el curso 2004-2005, con cambios en su composición, para aplicar los contenidos diseñados en las guías docentes de las asignaturas, y evaluar los resultados obtenidos. Para ello contó con el apoyo del Instituto de Ciencias de la Educación (Universidad de Alicante), a través de su Programa de Investigación Docente en Redes 2004-2005. En esta comunicación se da cuenta de los aspectos principales de la aplicación de las guías docentes durante el curso 2004-2005. Para ello, se hace un recorrido por: · El proceso de trabajo seguido por la red y por las asignaturas durante el curso 2004-2005. · Los resultados obtenidos, en términos de: rendimiento académico del alumnado; tiempo invertido y grado de dificultad encontrado; instrumentos de trabajo elaborados por la red (portafolio discente y docente). · Las conclusiones derivadas de la experiencia en las asignaturas, en las que se recogen tanto la visión de los estudiantes como la del profesorado. · Las propuestas de mejora de experiencias futuras.The research network named "Red de Estudio de la Docencia de Calidad en Trabajo Social (REDCATS-Segundo curso)", started its work in the 2003-2004 academic year with the aim of design the educational guides of the second year of the Bachelor in Social Work. The work has had continuity during 2004-2005 to apply the contents designed in the educational guides (syllabus) and to evaluate the results. In this task, the research network had the support of the Education’s Sciences Institute (University of Alicante), through its Research Networks Program in University Teaching 2004-2005. In this paper the network gives account of the main aspects of the application of the educational guides occurs during the 2004-2005 academic year. So, we explain: · The process of work followed by the network during that period. · The obtained results, in terms of: academic yield of the pupils; inverted time and degree of difficulty found; instruments of work elaborated by the network (student and teaching portfolio). · The conclusions of this experience, were we include both the vision of the students and the teaching staff perspective. · The proposals of improvement for future experiences

    A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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    The mycorrhiza-dependent defensin MtDefMd1 of Medicago truncatula acts during the late restructuring stages of arbuscule-containing cells.

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    Different symbiotic and pathogenic plant-microbe interactions involve the production of cysteine-rich antimicrobial defensins. In Medicago truncatula, the expression of four MtDefMd genes, encoding arbuscular mycorrhiza-dependent defensins containing an N-terminal signal peptide and exhibiting some differences to non-symbiotic defensins, raised over the time of fungal colonization. Whereas the MtDefMd1 and MtDefMd2 promoters were inactive in cells containing young arbuscules, cells with fully developed arbuscules displayed different levels of promoter activities, indicating an up-regulation towards later stages of arbuscule formation. MtDefMd1 and MtDefMd2 expression was absent or strongly down-regulated in mycorrhized ram1-1 and pt4-2 mutants, known for defects in arbuscule branching or premature arbuscule degeneration, respectively. A ~97% knock-down of MtDefMd1/MtDefMd2 expression did not significantly affect arbuscule size. Although overexpression of MtDefMd1 in arbuscule-containing cells led to an up-regulation of MtRam1, encoding a key transcriptional regulator of arbuscule formation, no morphological changes were evident. Co-localization of an MtDefMd1-mGFP6 fusion with additional, subcellular markers revealed that this defensin is associated with arbuscules in later stages of their life-cycle. MtDefMd1-mGFP6 was detected in cells with older arbuscules about to collapse, and ultimately in vacuolar compartments. Comparisons with mycorrhized roots expressing a tonoplast marker indicated that MtDefMd1 acts during late restructuring processes of arbuscule-containing cells, upon their transition into a post-symbiotic state

    Insights into the complex role of GRAS transcription factors in the arbuscular mycorrhiza symbiosis

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    Abstract To improve access to limiting nutrients, the vast majority of land plants forms arbuscular mycorrhizal (AM) symbioses with Glomeromycota fungi. We show here that AM-related GRAS transcription factors from different subgroups are upregulated during a time course of mycorrhization. Based on expression studies in mutants defective in arbuscule branching (ram1-1, with a deleted MtRam1 GRAS transcription factor gene) or in the formation of functional arbuscules (pt4-2, mutated in the phosphate transporter gene MtPt4), we demonstrate that the five AM-related GRAS transcription factor genes MtGras1, MtGras4, MtGras6, MtGras7, and MtRad1 can be differentiated by their dependency on MtRAM1 and MtPT4, indicating that the network of AM-related GRAS transcription factors consists of at least two regulatory modules. One module involves the MtRAM1- and MtPT4-independent transcription factor MtGRAS4 that activates MtGras7. Another module is controlled by the MtRAM1- and MtPT4-dependent transcription factor MtGRAS1. Genome-wide expression profiles of mycorrhized MtGras1 knockdown and ram1-1 roots differ substantially, indicating different targets. Although an MtGras1 knockdown reduces transcription of AM-related GRAS transcription factor genes including MtRam1 and MtGras7, MtGras1 overexpression alone is not sufficient to activate MtGras genes. MtGras1 knockdown roots display normal fungal colonization, with a trend towards the formation of smaller arbuscules

    Sequence analyses of of AM-dependent defensins MtDefMd1-4 and AM-unrelated defensins.

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    <p>Secondary structures of MtDefMd1-4 and AM-unrelated defensin-like proteins of <i>M</i>. <i>truncatula</i> (A), a representation of their three-dimensional structures (B and C), as well as surface electrostatics (D and E) are shown. Predicted signal peptides were removed from the mature amino acid sequences. Consecutively, the defensins were aligned based on their secondary structures. Background colorisation of the amino acids (in A) indicate hydrophobicity in a scale from red to blue (red: high hydrophobicity). A conserved aspartic acid in the C-terminal region of MtDefMds is marked with a grey triangel. For the bi-domain defensin MtDef5, the domains MtDef5A (including a 7 amino acid linker towards the MtDef5B domain) and MtDef5B are shown. After modelling the three-dimensional structures of the MtDefMd1-4, MtDef4 and MtDef5A/B defensins, they were visualized (B and C) and their surface electrostatics were calculated (D and E). The region congruent to the γ-core motif is indicated with arrows. The following proteins were used for comparisons in addition to MtDefMd1-4: MtDef5 A [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0191841#pone.0191841.ref065" target="_blank">65</a>], MtDef5 B [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0191841#pone.0191841.ref065" target="_blank">65</a>]and MtDef4 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0191841#pone.0191841.ref030" target="_blank">30</a>].</p
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