628 research outputs found
Magnetic fields, bremsstrahlung and synchrotron emission in the flare of 24 October 1969
Magnetic fields, bremsstrahlung, and synchrotron emission in solar flare of October 24, 196
Eigenelements of a General Aggregation-Fragmentation Model
We consider a linear integro-differential equation which arises to describe
both aggregation-fragmentation processes and cell division. We prove the
existence of a solution (\lb,\U,\phi) to the related eigenproblem. Such
eigenelements are useful to study the long time asymptotic behaviour of
solutions as well as the steady states when the equation is coupled with an
ODE. Our study concerns a non-constant transport term that can vanish at
since it seems to be relevant to describe some biological processes like
proteins aggregation. Non lower-bounded transport terms bring difficulties to
find estimates. All the work of this paper is to solve this problem
using weighted-norms
DICER-LIKE2 plays a primary role in transitive silencing of transgenes in Arabidopsis.
Dicer-like (DCL) enzymes play a pivotal role in RNA silencing in plants, processing the long double-stranded RNA (dsRNA) that triggers silencing into the primary short interfering RNAs (siRNAs) that mediate it. The siRNA population can be augmented and silencing amplified via transitivity, an RNA-dependent RNA polymerase (RDR)-dependent pathway that uses the target RNA as substrate to generate secondary siRNAs. Here we report that Arabidopsis DCL2-but not DCL4-is required for transitivity in cell-autonomous, post-transcriptional silencing of transgenes. An insertion mutation in DCL2 blocked sense transgene-induced silencing and eliminated accumulation of the associated RDR-dependent siRNAs. In hairpin transgene-induced silencing, the dcl2 mutation likewise eliminated accumulation of secondary siRNAs and blocked transitive silencing, but did not block silencing mediated by primary siRNAs. Strikingly, in all cases, the dcl2 mutation eliminated accumulation of all secondary siRNAs, including those generated by other DCL enzymes. In contrast, mutations in DCL4 promoted a dramatic shift to transitive silencing in the case of the hairpin transgene and enhanced silencing induced by the sense transgene. Suppression of hairpin and sense transgene silencing by the P1/HC-Pro and P38 viral suppressors was associated with elimination of secondary siRNA accumulation, but the suppressors did not block processing of the stem of the hairpin transcript into primary siRNAs. Thus, these viral suppressors resemble the dcl2 mutation in their effects on siRNA biogenesis. We conclude that DCL2 plays an essential, as opposed to redundant, role in transitive silencing of transgenes and may play a more important role in silencing of viruses than currently thought
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Carbonates in Skeleton-poor Seas: New Insights From Cambrian and Ordovician Strata of Laurentia
Calcareous skeletons evolved as part of the greater EdiacaranβCambrian diversification of marine animals. Skeletons did not become permanent, globally important sources of carbonate sediment, however, until the Ordovician radiation. Representative carbonate facies in a Series 3 (510β501 Ma) Cambrian to Tremadocian succession from western Newfoundland, Canada, and Ordovician successions from the Ibex area, Utah, USA, show that, on average, Cambrian and Tremadocian carbonates contain much less skeletal material than do post-Tremadocian sediments. Petrographic point counts of skeletal abundance within facies and proportional facies abundance in measured sections suggest that later Cambrian successions contain on average <5% skeletal material by volume, whereas the skeletal content of post-Tremadocian Ordovician sections is closer to ~15%. A compilation of carbonate stratigraphic sections from across Laurentia confirms that post-Tremadocian increase in skeletal content is a general pattern and not unique to the two basins studied. The long interval (~40 myr) between the initial Cambrian appearance of carbonate skeletons and the subsequent Ordovician diversification of heavily skeletonized organisms provides an important perspective on the Ordovician radiation. Geochemical data increasingly support the hypothesis that later Cambrian oceans were warm and, in subsurface water masses, commonly dysoxic to anoxic. We suggest that surface waters in such oceans would have been characterized by relatively low saturation states for calcite and aragonite. Mid-Ordovician cooling would have raised oxygen concentrations in subsurface water masses, establishing more highly oversaturated surface waters. If correct, these links could provide a proximal trigger for the renewed radiation of heavily skeletonized invertebrates and algae
Distribution of Oolitic Sediment Along a Beach-to-Offshore Transect, Pigeon Cay, Cat Island, Bahamas: New Insights Into Modern Ooid Formation
Ooids are a common component of ancient carbonate rocks, but their origin and distribution in Holocene deposits and modem carbonate sands are not fully understood. Even though ooids are well documented from several localities in the Bahamian Archipelago, their occurrence on Cat Island has not been previously studied in detail. In this study we examined the composition and texture of beach sand and six sediment samples collected from the sea floor at approximately 50-meter intervals along an estimated 300 m transect at Pigeon Cay, Cat Island
Response by Sperber et al to letter regarding article, "Serum Anti-NMDA (N-Methyl-D-Aspartate)-Receptor Antibodies and Long-Term Clinical Outcome After Stroke (PROSCIS-B)"
Qualitative characterization of healthcare wastes
The biological hazard inherent in the clinical wastes should be considered during the management and treatment process as well as the disposal into the environment. In this chapter, the risks associated with the clinical wastes as well as the management of these wastes are discussed. The chapter focused on reviewing the types of healthcare wastes generated from hospitals and clinics as well as the regulations and management practices used for these wastes. Moreover, the health risk associated with the infectious agents which have the potential to be transmitted into the environment. It has appeared that the clinical wastes represent real hazards for the human health and the environment if they were not managed properly
System Dynamics Model For Hospital Waste Characterisation and Generation in Developing Countries.
Waste management policy makers always face the problem of how to predict the future amount and composition of medical solid waste, which in turn will help determine the most appropriate treatment, recycling and disposal strategy. An accurate prediction can assist in both the planning and design of medical solid waste management systems. Insufficient budget and unavailable management capacity are the main reasons for the scarcity of medical solid waste quantities and components historical records, which are so important in long-term system planning and short-term expansion programs. This paper presents a new technique, using system dynamics modelling, to predict generated medical solid waste in a developing urban area, based on a set of limited samples from Jenin District hospitals, Palestine. The findings of the model present the trend of medical solid waste generation together with its different components and indicate that a new forecasting approach may cover a variety of possible causative models and track inevitable uncertainties when traditional statistical least-squared regression methods are unable to handle such issues
Quantification of growth factors in allogenic bone grafts extracted with three different methods
CARBONATES IN SKELETON-POOR SEAS: NEW INSIGHTS FROM CAMBRIAN AND ORDOVICIAN STRATA OF LAURENTIA
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