Enhancing extensive reading with data-driven learning

This paper investigates using data-driven learning (DDL) as a means of stimulating greater lexicogrammatical knowledge and reading speed among lower proficiency learners in an extensive reading program. For 16 weekly 90-minute sessions, an experimental group (12 students) used DDL materials created from a corpus developed from the Oxford Bookworms Graded Readers, while a control group (10 students) had no DDL input. Both classes were required to read a minimum of 200,000 words during the course. An embedded-experiment design (Edmonds & Kennedy, 2017) was adopted consisting of both qualitative and quantitative forms of investigation. Quantitative data from the Vocabulary Levels Test by Nation and Beglar (2007) and a C-test (Klein-Braley & Raatz, 1984) constructed from an upper-level Bookworms reader found statistically significant lexicogrammatical improvements for both groups, but greater improvement took place within the control group. Qualitative data derived from a repertory grid analysis of student constructs revealed several possible reasons for the experimental group’s lack of engagement with DDL. The study concludes that careful attention to students’ learning preferences and a softening of the DDL approach may ensure better results with lower proficiency learners

SB46-20/21: Resolution Establishing the ASUM Legislative Priorities

SB46-20/21: Resolution Establishing the ASUM Legislative Priorities. This resolution passed on a 19Y-1N-0A vote during the December 3, 2020 meeting of the Associated Students of the University of Montana (ASUM)

Red coralline algae assessed as marine pH proxies using 11B MAS NMR

Reconstructing pH from biogenic carbonates using boron isotopic compositions relies on the assumption that only borate, and no boric acid, is present. Red coralline algae are frequently used in palaeoenvironmental reconstruction due to their widespread distribution and regular banding frequency. Prior to undertaking pH reconstructions using red coralline algae we tested the boron composition of the red coralline alga Lithothamnion glaciale using high field NMR. In bulk analysed samples, thirty percent of boron was present as boric acid. We suggest that prior to reconstructing pH using coralline algae 1) species-specific boron compositions and 2) within-skeleton special distributions of boron are determined for multiple species. This will enable site selective boron analyses to be conducted validating coralline algae as palaeo-pH proxies based on boron isotopic compositions

The moral and sentimental work of the clinic: the case of genetic syndromes

This paper reports on the genetics clinic and examines the wider functions it provides for parents who have a child with learning disabilities that may be associated with an underlying genetic cause. It derives from an ethnographic study of one clinical genetics team within a UK clinical genetics service and their clinical caseload, specifically their cases of genetic syndromes associated with dysmorphology, a speciality within clinical genetics. Dysmorphology is the medical study of abnormal forms in the human and is concerned with the identification and classification of a variety of congenital malformations. Our analysis of the clinical consultations and subsequent interviews with parents indicate that obtaining a genetic diagnosis and classification of their child’s problems was not the sole function of these consultations. In addition, the clinic provides parents with moral absolution from having ‘caused’ their child’s problems and is an important site for the sentimental and celebratory focus on the child. Thus, the role of the clinical genetics service is not merely to assemble a diagnosis from the available information and to provide a source of expert opinion on the causes of the condition, but to provide reassurance to parents who might otherwise blame themselves (or be blamed by others) for their child’s condition. An important aspect of these consultations was the sentimental work of repairing the child, providing a sphere in which the development and behaviour of the child is discussed in favourable terms, and given assurances of ‘normal’ parenting and family life, often in marked contrast to their experience in the wider public world. Thus, the work of establishing diagnostic categories also allows important moral and sentimental work to be accomplished within the clinic

Kinscapes, timescapes and genescapes: families living with genetic risk

This article synthesises recent research examining how families live with genetic risk and the processes of genetic decision-making and disclosure among family members who have been or are at risk of transmitting a familial genetic condition. Its aim is to generate substantive theory that can inform our understanding of the interactional processes at work in the distribution of mutual knowledge and awareness of genetic risk in families. The article is structured around three interrelated concepts. Kinscape refers to the constellation of relations and relatedness that are recognised practically; timescape to the multiple temporal frames of social relations and their transformation and genescape to the constellation of knowledge, belief and practice surrounding genetic inheritance. All three concepts are simultaneously natural and cultural. Their intersections create the conditions of kinship and genetics

The Polarizing Impact of Science Literacy and Numeracy on Perceived Climate Change Risks

Seeming public apathy over climate change is often attributed to a deficit in comprehension. The public knows too little science, it is claimed, to understand the evidence or avoid being misled. Widespread limits on technical reasoning aggravate the problem by forcing citizens to use unreliable cognitive heuristics to assess risk. An empirical study found no support for this position. Members of the public with the highest degrees of science literacy and technical reasoning capacity were not the most concerned about climate change. Rather, they were the ones among whom cultural polarization was greatest. This result suggests that public divisions over climate change stem not from the public’s incomprehension of science but from a distinctive conflict of interest: between the personal interest individuals have in forming beliefs in line with those held by others with whom they share close ties and the collective one they all share in making use of the best available science to promote common welfare

COVID-19 and Prisoners’ Rights

As COVID-19 continues to spread rapidly across the country, the crowded and unsanitary conditions in prisons, jails, juvenile detention, and immigration detention centers leave incarcerated individuals especially vulnerable. This chapter will discuss potential avenues for detained persons and their lawyers seeking to use the legal system to obtain relief, including potential release, during this extraordinary, unprecedented crisis

Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus

Regions of highly repetitive DNA, such as those found in the nucleolus, show a self-organization that is marked by spatial segregation and frequent self-interaction. The mechanisms that underlie the sequestration of these sub-domains are largely unknown. Using a stochastic, bead-spring representation of chromatin in budding yeast, we find enrichment of protein-mediated, dynamic chromosomal cross-links recapitulates the segregation, morphology and self-interaction of the nucleolus. Rates and enrichment of dynamic crosslinking have profound consequences on domain morphology. Our model demonstrates the nucleolus is phase separated from other chromatin in the nucleus and predicts that multiple rDNA loci will form a single nucleolus independent of their location within the genome. Fluorescent labeling of budding yeast nucleoli with CDC14-GFP revealed that a split rDNA locus indeed forms a single nucleolus. We propose that nuclear sub-domains, such as the nucleolus, result from phase separations within the nucleus, which are driven by the enrichment of protein-mediated, dynamic chromosomal crosslinks

Analysis of whole exome sequencing with cardiometabolic traits using family-based linkage and association in the IRAS Family Study

Family-based methods are a potentially powerful tool to identify trait-defining genetic variants in extended families, particularly when used to complement conventional association analysis. We utilized two-point linkage analysis and single variant association analysis to evaluate whole exome sequencing (WES) data from 1,205 Hispanic Americans (78 families) from the Insulin Resistance Atherosclerosis Family Study. WES identified 211,612 variants above the minor allele frequency threshold of ≥0.005. These variants were tested for linkage and/or association with 50 cardiometabolic traits after quality control checks. Two-point linkage analysis yielded 10,580,600 LOD scores with 1,148 LOD scores ≥3, 183 LOD scores ≥4, and 29 LOD scores ≥5. The maximal novel LOD score was 5.50 for rs2289043:T\u3eC, in UNC5C with subcutaneous adipose tissue volume. Association analysis identified 13 variants attaining genome-wide significance (pT in APOA5, and triglyceride levels (p=3.67×10-10). Overall, there was a 5.2-fold increase in the number of informative variants detected by WES compared to exome chip analysis in this population, nearly 30% of which were novel variants relative to dbSNP build 138. Thus, integration of results from two-point linkage and single-variant association analysis from WES data enabled identification of novel signals potentially contributing to cardiometabolic traits

The Tragedy of the Risk-Perception Commons: Culture Conflict, Rationality Conflict, and Climate Change

31 pagesThe conventional explanation for controversy over climate change emphasizes impediments to public understanding: limited popular knowledge of science, the inability of ordinary citizens to assess technical information, and the resulting widespread use of unreliable cognitive heuristics to assess risk. A large survey of U.S. adults (N = 1540) found little support for this account. On the whole, the most scien- tifically literate and numerate subjects were slightly less likely, not more, to see climate change as a serious threat than the least scientifically literate and numerate ones. More importantly, greater scientific literacy and numeracy were associated with greater cultural polarization: respondents predisposed by their values to dismiss climate change evidence became more dismissive, and those predisposed by their values to credit such evidence more concerned, as science literacy and numeracy increased. We suggest that this evidence reflects a conflict between two levels of rationality: the individual level, which is characterized by the citizens’ effective use of their knowledge and reasoning capacities to form risk perceptions that express their cultural commitments; and the collective level, which is characterized by citizens’ failure to converge on the best available scientific evidence on how to promote their common welfare. Dispelling this “tragedy of the risk-perception commons,” we argue, should be understood as the central aim of the science of science communication